Translational Research Initiative for Hearing (TRIH) Grant

Action on Hearing Loss


Grant amount: Up to £300,000

Next anticipated deadline: Feb 28, 2019 9:00am PST (Letter of inquiry)

Later anticipated deadlines: May 31, 2019 10:00am PDT (Full proposal)

Applicant type: Postdoctoral Researcher Working Professional Faculty

Funding uses: Research

Location of project: Anywhere in the world

Location of residency: Anywhere in the world

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Overview:

Action on Hearing Loss TRIH Grant 

Our Translational Research Initiative for Hearing (TRIH) Grant aims to help strengthen the translation of fundamental research towards patient benefit. It supports:

  • Research with a strong commercial potential that is likely to attract follow-on funding at the conclusion of the grant.
  • Studies that will facilitate and enable the progression of promising basic research towards testing in clinical trials.

Requirements

The scope of the TRIH call varies from year to year. This year, applications will be accepted in the following areas:

Small molecule, gene or cell-based approaches for the treatment of hearing loss or tinnitus.

 This can include: 

  • Studies which will enable lead optimisation and/or candidate selection.
  • Pharmacokinetics/Pharmacodynamics (PKPD) studies.
  • Safety/toxicology studies.
  • Drug repositioning/repurposing (applications must contain preliminary data supporting the proposed approach) 

Research that addresses at least one of the following “TRIH Challenge” topics

  • Validation of therapeutic targets for the treatment of hearing loss or tinnitus (applications must contain preliminary data supporting the proposed approach). 
  • Studies to strengthen confidence that a target or therapeutic approach will be applicable to human hearing loss or tinnitus. 
  • Preclinical model validation i.e. studies to increase the understanding of invivo or in-vitro model relevance to human hearing loss or tinnitus. 
  • Identification/validation of methods or outcomes that could be used for one or more of the following: 
  • Patient selection/stratification for clinical trials
  • Robust measurement of treatment responses in clinical trials. 

You can learn more about this opportunity by visiting the funder's website.

Ineligibility:

  • The TRIH Grant does not support basic research into the causes and underpinning biology of hearing loss and tinnitus or the development of devices or software.
  • Please note that as a charity, it is our policy not to fund any indirect costs or the salaries of permanent employees.
  • This year, applications will not be accepted in the following areas:
    • Basic research into the causes and underpinning biology of hearing loss and tinnitus
    • The development of devices or software
    • The optimization of current clinical protocols
    • Health service studies