Glenn/AFAR Breakthroughs in Gerontology (BIG) Award

American Federation for Aging Research

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Grant amount: Up to US $200,000

Anticipated deadline: Dec 17, 2019 2:00pm PST (Letter of inquiry)

Applicant type: Faculty

Funding uses: Research

Location of project: United States

Location of residency: Anywhere in the world

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About this funder:



Sponsored by The Glenn Foundation for Medical Research, in collaboration with the American Federation for Aging Research (AFAR), the "Breakthroughs in Gerontology (BIG)" initiative provides timely support to a small number of research projects that are building on early discoveries that show translational potential for clinically-relevant strategies, treatments and therapeutics, addressing human aging and health span.

Two awards will be made. The amount and the duration of the award may be modified if during the review process or at the funding stage it is evident that such modifications would better serve the objectives of the program.

The following types of studies using one or more of these models will be considered:

  • Human subjects
  • Human cells and tissues
  • Mice or other mammals.

Proposals using other types of models (i.e. yeast, drosophila melanogaster, c. elegans, etc.) will only be considered when there is compelling justification that these studies may be directly relevant to human health and aging (or "the human condition".)

Recipients of this award are expected to attend the AFAR Grantee Conference. The purpose of the meeting is to promote scientific and personal exchanges among recent AFAR grantees and experts in aging research.

You can learn more about this opportunity by visiting the funder's website.


  • To be eligible, applicants must at the time they submit their proposal be full-time faculty members at the rank of Assistant Professor or higher.
  • A strong record of independent publication beyond the postdoctoral level is a requirement.
  • The proposed research must be conducted at any type of not-for-profit setting in the United States.
  • Former AFAR Research Grant awardees may apply.
  • Applications are reviewed based on the following criteria:
    • Qualifications and research record of the applicant
    • Quality, promise and feasibility of the proposed research
    • Translational potential and relevance to human aging and health span
    • Excellence of the research environment


  • Priority will be given to proposals that have a near-term potential for translation.


  • Individuals who are employees in the NIH Intramural program are not eligible.
  • If you are applying for a AFAR Research Grant, you may not also apply for the Glenn/AFAR BIG Award.