Imaging, Biomarkers and Digital Pathomics for the Early Detection of Premetastatic Aggressive Cancer (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: Nov 10, 2021 (Letter of inquiry)

Later deadlines: Dec 10, 2021 (Full proposal)

Grant amount: Unspecified amount

Fields of work: Biomedical Imaging Cancer/Oncology

Applicant type: Government Entity, Indigenous Group, Nonprofit

Funding uses: Research

Location of project: United States

Location of residency: United States

Overview:

NOTE: Letter of Intent

  • Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review.

This Funding Opportunity Announcement (FOA) will support the development and characterization of state-of-the-art projects that include imaging, biomarkers, digital pathomic and other omic data integration strategies for improving current approaches for the earliest detection of premetastatic aggressive cancer as well as identifying precancerous lesions that will subsequently demonstrate an aggressive phenotype. This FOA specifically attempts to address and improve diagnostic uncertainty in clinical decisions in a technology agnostic manner by improving sensitivity and specificity of applied tests. N-dimensional co-registered, cross-correlated imaging data integrated with multiplexed biomarker results and digital pathomics using analytic strategies such as artificial intelligence and virtual reality visualization for improving cancer research discovery are encouraged. The projects supported by this FOA will collectively participate in the existing Consortium for Imaging and Biomarkers (CIB) Research Program. The goals of the CIB are to: (1) improve diagnostic performance by developing methodology for the early identification of lethal cancer versus non-lethal disease, (2) to minimize/better manage overdiagnosis and (3) to reduce false positives and false negatives.

We've imported the main document for this grant to give you an overview. You can learn more about this opportunity by visiting the funder's website.

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This page was last reviewed July 22, 2021 and last updated May 02, 2019