Novel Assays to Address Translational Gaps in Treatment Development (UG3/UH3 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: Sep 20, 2021 (Letter of inquiry)

Later deadlines: Oct 20, 2021 (Full proposal), Jan 21, 2022 (Letter of inquiry), Feb 21, 2022 (Full proposal)

Grant amount: Unspecified amount

Fields of work: Neuroscience Psychology

Applicant type: Organizations

Funding uses: Biomedical, Behavioral

Location of project: Anywhere in the world

Location of residency: Anywhere in the world

Overview:

NOTE:

  • Applications are due by 5pm submitter's local time. 
  • Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review.

The overall goal of this initiative is to identify neurophysiological measures potential assays for treatment development research. The funding opportunity announcement (FOA) will support efforts to optimize and evaluate measures of neurophysiological processes that are disrupted within or across mental disorders in both healthy humans and in another species relevant to the therapeutic development pipeline. The initiative will support initial proof of concept studies aimed at identifying measures for potential development as preclinical assays for evaluating potential new drug and device therapies and their targets. Data will also reveal assay measures where the performance between preclinical animal species and humans is dissimilar, thus establishing a firm basis for limiting speculative extrapolations of preclinical animal findings to humans.

The ultimate practical goal of this FOA is to improve the efficiency of the therapeutic development process by identifying coherence of measures and inconsistencies between the preclinical screening pipeline and clinical evaluation of new treatment candidates and thereby hasten the development of more effective treatments for mental disorders.

We've imported the main document for this grant to give you an overview. You can learn more about this opportunity by visiting the funder's website.

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This page was last reviewed March 12, 2019 and last updated March 12, 2019