Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed) (353369)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: May 1, 2025 (Letter of inquiry)

Later deadlines: Jun 2, 2025 (Full proposal), May 1, 2026 (Letter of inquiry), Jun 2, 2026 (Full proposal)

Grant amount: Up to US $275,000

Fields of work: Pharmacology Rare Diseases

Applicant type: Nonprofit, Government Entity, Indigenous Group, For-Profit Business

Funding uses: Research

Location of project: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico Show all

Location of residency: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico Show all

Overview:

NOTE: All applications are due by 5:00 PM local time of applicant organization.

This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development. In addition to preclinical efficacy, accompanying pharmacodynamic and pharmacokinetic studies would be supported. Therapeutic agents include small molecules, biologics or biotechnology-derived products. The goal of this NOFO is to spur therapeutic development for a variety of rare diseases by advancing projects to the point where they would attract subsequent investment supporting full Investigational New Drug (IND) application development or progression to clinical trials in the case of repurposing or repositioning.

We've imported the main document for this grant to give you an overview. You can learn more about this opportunity by visiting the funder's website.

US Dept. of Health & Human Services: National Institutes of Health (NIH)
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This page was last reviewed April 07, 2024 and last updated April 07, 2024