Best Albany County Grants for Nonprofits in Wyoming

The BJA FY 2026 Prosecuting Cold Cases Using DNA program aims to enhance public safety and justice by supporting prosecutors in the investigation and prosecution of violent cold case crimes with developed DNA profiles. This funding opportunity, provided by the US DOJ's OJP Bureau of Justice Assistance, facilitates crucial investigative and forensic activities to increase successful prosecutions and provide resolution for victims and their families. Full applications are due by November 5, 2026.

The BJA FY 2026 Veterans Treatment Court Program aims to enhance operations for veterans in the criminal justice system, focusing on reducing substance use, including opioids and alcohol. It integrates treatment for substance use and mental health disorders within a judicial framework, targeting high-risk veterans. This initiative not only addresses public safety concerns but also aims to provide necessary support and resources for veterans dealing with issues like PTSD and traumatic brain injury, fostering rehabilitation and recovery.

The OJJDP FY 2026 Juvenile Drug Treatment Court Program aims to enhance juvenile drug treatment courts (JDTCs) across the U.S. by supporting states, local courts, and Tribal governments. This initiative focuses on improving outcomes for youth dealing with substance use disorders or co-occurring mental health issues. The program underscores the commitment of the Office of Justice Programs to strengthen community safety and provide vital resources for effective intervention and support.

The OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance program aims to enhance the ability of state, Tribal, and local agencies to effectively address cases of missing and exploited children. This initiative will support multidisciplinary teams, including law enforcement and child protection personnel, to improve investigations and prosecutions. By providing essential resources and training, the program seeks to strengthen responses to protect vulnerable children and combat related public safety issues.

The OJJDP FY 2026 Community and Schools Youth Drug Prevention Program aims to combat youth substance use through comprehensive prevention strategies. This initiative invites applications from states, local governments, and nonprofit organizations to develop programs that educate and support youth in schools and community settings. By fostering collaboration with law enforcement and community coalitions, the program seeks to build capacity and implement effective interventions to protect the well-being of American youth.

The FY 2027 Department of War Multidisciplinary Research Program of the University Research Initiative (MURI) aims to fund U.S. academic teams conducting innovative research to tackle complex challenges for the Department of War. Established in 1985, MURI promotes collaboration among diverse scientific disciplines, enhancing the defense workforce and addressing critical areas of interest through multidisciplinary research efforts at U.S. universities.

The BJA FY 2026 National Center for Veterans Justice aims to enhance support for veterans in the criminal justice system. By providing specialized training and resources to law enforcement and service providers, the center will address critical gaps in veteran identification and coordination among agencies. This initiative seeks to improve outcomes for veterans experiencing issues like PTSD and military sexual trauma, ultimately strengthening public safety and ensuring effective responses to their unique needs.

Dick & Judy Hoyt Inclusion Grant

The Doug Flutie, Jr. Foundation for Autism is excited to collaborate with the Hoyt Foundation for the Dick and Judy Hoyt Grant for Inclusion. Our joint effort is driven by a shared vision of fostering a society where individuals with autism and other disabilities are embraced and valued within their communities. In tribute to the pioneering spirit of Dick and Judy Hoyt, we will be distributing $50,000 through this community grant to support people with autism and other disabilities. Successful ways grant funds can be used: 

• Side-by-side participation with non-disabled peers in a swim program, the grant provides a private lifeguard to allow individualized support to ensure an inclusive experience.
• Grant provides the purchase of a racing chair to allow an individual with a disability to run in races with non-disabled peers.
• Competitive horseback riding supported by the grant to purchase specialized equipment to allow a rider to compete against non-disabled peers.
• Grant provides the purchase of an adaptive ski prosthetic to allow an individual to participate side by side with non-disabled peers on their high school ski teams.
• Participation in dance training and competitions to allow a student with a disability to compete in a dance competition with non-disabled peers, grant lessons, and staff to assist in dance training.
• Grant provides a mobile stand to allow a student with a disability to participate side by side with non-disabled peers in the college marching band. 

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Resident Research Award

Provides residents and fellows an opportunity to attend and present their scientific research at the SIR Annual Scientific Meeting. The intent is to expose young researchers who wish to further their careers in interventional radiology.

Award

Up to two recipients will receive complimentary registration and a travel stipend of $1,000.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Research Scientist Award

Recognizes the contributions and accomplishments of PhD scientists and engineers at all levels of training for their basic and preclinical research on the topic of interventional radiology.

Award

Up to two recipients will receive complimentary registration and a travel stipend of $1,000.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Dr. Gary J. Becker Young Investigator Award

Promotes excellence in academic research for members early in their careers. This award honors the founding editor of the Journal of Vascular and Interventional Radiology (JVIR) and recognizes the importance of the young investigator in developing interventional solutions for the future.

About

In 1990, SIR Foundation established the Dr. Gary J. Becker Young Investigator Award as a way to recognize promising young practitioners of interventional radiology early in their careers and encourage their pursuit of academic careers. Each year, the author of the most outstanding clinical science research paper submitted receives this distinguished award.

Award

$3,000 honorarium along with complimentary registration to the SIR Annual Scientific Meeting.

The award will be presented during the SIR Foundation Awards Ceremony at the SIR Annual Scientific Meeting.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Dr. Constantin Cope Medical Student Research Award

Introduces interested medical students to the greater interventional radiology community at the SIR Annual Scientific Meeting. Recognizes the student author of an accepted abstract that best honors the spirit of inventiveness and scientific purity.

Award

Up to two recipients will receive complimentary registration and a travel award of up to $1,000.

Dr. Barry T. Katzen Master Clinician Award

Honors an interventional radiologist who exemplifies dedication to clinical practice, patient care, diligence in their work and continuous improvement within the field and who has also made a demonstrable impact at their institution or practice as a result.

About

The Dr. Barry T. Katzen Master Clinician Award seeks to honor an interventional radiologist who exemplifies dedication to clinical practice, patient care, diligence in their work and continuous improvement within the field as well as who has made a demonstrable impact at their institution or practice as a result. This award recognizes individuals who have made significant contributions to enhancing patient outcomes and advancing the reputation and practice of interventional radiology through their hard work, commitment and, most importantly, clinical practice. The award is being given in the name of Barry T. Katzen, MD, FSIR, who pioneered clinical practice for IR in 1976 and became a vocal advocate, champion and example for colleagues of the importance of IR being a clinical discipline for advancement of the specialty.

The recipient will receive:

• Complimentary annual meeting registration
• Recognition during the SIR Annual Scientific Meeting

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Excellence in Innovation Award

Fund compelling, novel ideas that lead to improved health outcomes in IR.

About

Interventional radiologists create and introduce novel, minimally invasive procedures and devices that help solve some of our toughest medical challenges. To continue this rich history of innovation in IR, the purpose of this award is to fund compelling, novel ideas that lead to improved health outcomes in IR.

Innovation, for this purpose, is broadly defined as any use of emerging methods, new devices, new procedures or new technologies, such as artificial intelligence and nanotechnology, that display an exceptional degree of potential for transforming and advancing the specialty of interventional radiology.

The Annual Meeting Research Award Committee selects one recipient for this award each year.

The recipient will receive:

• Complimentary annual meeting registration
• Travel stipend up to $1,000
• The opportunity to present their research as well as meet peers, network with senior scientists and participate in learning opportunities at the SIR Annual Scientific Meeting
• Recognition during the SIR Annual Scientific Meeting

About the ASHFoundation

ASHFoundation supports innovators and sparks innovation in communication sciences. We give early support to promising students, researchers, and clinicians exploring bold ideas to transform the field and improve people's lives.

Artificial Intelligence in Communication Sciences and Disorders Research Grant

About

The American Speech-Language-Hearing Foundation (ASHFoundation) invites investigators to submit proposals for up to four research grants ranging from $25,000 to $50,000. The Artificial Intelligence in Communication Sciences and Disorders Research Grant (AI in CSD Research Grant) supports interdisciplinary studies that advance the ethical, clinically and scientifically grounded application and integration of artificial intelligence (AI) into communication sciences and disorders (CSD) practice and service delivery. Funding may be applied to one- or two-year studies.

Specific Objectives of the Funding Opportunity

As part of this initiative, the ASHFoundation invites proposals that implement AI technologies to transform clinical practice, education, and research in CSD. Proposals that are submitted under this funding opportunity must meet the following:

• Include interdisciplinary research teams that integrate clinicians and AI researchers,
• Address clinically relevant questions or have a clear translational potential, and
• Cover one or more of the following priority areas: AI-driven assessment and diagnosis; personalized and adaptive interventions; equitable access to care; data infrastructure for predictive analytics; technology innovation; prevention for public health; and ethical standards for AI integration.

Grant Guidelines

To advance its mission to build a responsible and equitable technology ecosystem, the Kapor Foundation makes strategic grants across three focus areas: (1) Computing Education, (2) Innovation, and (3) Governance.

Within each focus area, we fund research on critical topics at the intersection of racial equity and tech, capacity-building that strengthens coalitions and movement-building infrastructure, and policy advocacy that drives systemic change.

Funding Priorities

We fund organizations and initiatives aligned with our core focus areas:

Given advances in Al, a new vision of education is urgently needed — one that ensures students are equipped with the technical skills to build emerging technologies and the critical skills to navigate their socio-technical implications. We fund computing education initiatives across K-12, postsecondary, and alternative pathways that expand computing participation at scale, shift policy to ensure equitable access, and expand the pipeline of educators prepared to teach computing.

2. 

Al is being designed, developed, and deployed rapidly, yet the communities most affected by its impacts are largely excluded from its creation and subsequent economic benefits. We support organizations and individuals that build responsible Al technologies, leverage technology to close gaps in access and opportunity, and invest in initiatives and coalitions that advance responsible Al in the entrepreneurship and venture capital ecosystems.

3.

As Al adoption accelerates, bolder approaches to regulation are necessary to protect marginalized communities from technological harm, expand economic opportunity, and ensure the benefits of technology reach everyone. We support efforts that build awareness of key policy issues, develop policy agendas, and mobilize coalitions.

For 2026, our priority advocacy areas are: 1) computing education, 2) algorithmic bias, 3) Al safeguards for children, 4) data center development, and 5) surveillance and civil rights.

The MPPEP Phase 3 program aims to enhance processing capabilities for invasive, wild-caught catfish, benefiting both processors and fishers. By increasing processing capacity and volume, the initiative seeks to create fair wages and stable job opportunities, fostering economic growth in rural areas. This grant will support innovative strategies that ensure sustainable practices and elevate incomes within the community, thus contributing to the overall development of the meat and poultry sector.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Interventional Research Studies of Brentuximab Vedotin-Based Novel Combinations in AITL and PTCL-NOS

This competitive program is designed to support interventional InvestigatorSponsored Research aimed at generatin clinical evidence for brentuximab vedotin in novel combination approaches in angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma–not otherwise specified (PTCL-NOS).

Project Types and Area of Interest

Studies considered for Pfizer support should address key clinical and scientific gaps in the use of brentuximab vedotin in AITL and PTCL-NOS irrrespective of CD30 expression, with a focus on evaluating the safety and efficacy of novel brentuximab vedotin–based combinations with therapies available for PTCL treatment that are supported by a clear scientific rationale grounded in mechanism of action and/or disease biology.

About Disabled Veterans National FoundationThe Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability. The Disabled Veterans National Foundation (DVNF) provides critically needed support to disabled and at-risk veterans who leave the military wounded—physically or psychologically—after defending our safety and freedom.

About Grants to Provide Stability (GPS) ProgramThe Disabled Veterans National Foundation’s GPS (Grants to Provide Stability) Program is a grant program for veterans who find themselves in temporary financial setback. DVNF will provide up to $1,000 (not guaranteed) to help eligible veterans pay for rent or mortgage and essential utilities such as water or electricity. Applications are open on a monthly basis. Please note that each veteran can only be approved once per fiscal year (October – September).

Creative West

Established in 1974 as a nonprofit U.S. Regional Arts Organization (USRAO), Creative West was founded on the belief that place matters to the creative process. Fifty years later, communities of place, practice, experience, and identity remain fundamental to our work, framing our understanding of how culture is creatively produced and collectively experienced.

Creative West empowers artists and culture-makers with direct, practical resources, delivered regionally.

We offer practical, equity-centered learning experiences and funding opportunities that connect and inspire artists, culture-bearers and communities to build a more inclusive sector, strengthen the arts field, and catalyze change.

National Arts Futures Fellowship

The National Arts Futures Fellowship (NAFF) is a six-month virtual leadership development program rooted in democracy, wellness, and belonging. It calls on early and mid-career arts and culture professionals from all backgrounds to step into their power as civic leaders and cultural innovators—building the skills, networks, and vision needed to shape a future where creativity drives justice, care, and connection.

Fellows join a national network committed to strengthening public life, nurturing collective wellness, and fostering deep belonging across communities. Together, they learn, experiment, and act—advancing a shared vision of leadership that is sustainable, community-rooted, and future-focused.

Each fellow enters NAFF with a Personal Action Project (PAP)—a concrete idea they will develop and implement with support from peers, coaches, guest experts, and flexible seed funding of $250–$1,000. Projects may include launching a cultural initiative, organizing a community campaign, supporting artist-led advocacy, seeking a public leadership role, or piloting another form of civic or community action. Throughout the fellowship, each project evolves through coaching, peer feedback, strategy sessions, and real-world experimentation. Fellows conclude the program by sharing their project, leadership growth, and next steps at the National Fellows Summit.

What’s New in Cohort Two?

• Cohort Two expands NAFF from six to seven monthly sessions and adds two new elements that support fellows in moving their Personal Action Projects from development into implementation:
• Seed Funding: Fellows may request $250–$1,000 in flexible funding to test, pilot, or implement their projects during the fellowship.
• Artists Thrive Framework: Fellows will use the framework to assess their work, identify opportunities for growth, and strengthen artist-led advocacy, collaboration, and community impact.

Guiding Principles

• Democracy — Use the arts to strengthen civic participation, expand public trust, and make decision-making more accessible and inclusive.
• Wellness — Treat care, rest, and healing as strategic leadership tools for sustaining movements and communities.
• Belonging — Create spaces where leaders can thrive together across differences, build trust, and celebrate shared humanity.

What kinds of projects are supported?

Examples: Running for office, launching cultural programs, organizing campaigns, supporting policies. Projects can be local, regional, or national in scope.

About Disabled Veterans National FoundationThe Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability. The Disabled Veterans National Foundation (DVNF) provides critically needed support to disabled and at-risk veterans who leave the military wounded—physically or psychologically—after defending our safety and freedom.About Comfort Kits and Grab N' Go ProgramIn addition to our direct outreach, the DVNF also supports like-minded organizations that share our commitment to serving veterans. Approved organizations can apply to receive Comfort Kits for distribution to veterans in their communities. These kits are designed to meet the unique needs of veterans and offer critical support where they are needed most.

Quality Improvement Grant Request for Proposals

Optimizing Maternal RSV Immunization Delivery: A Systems-Based Quality Improvement Initiative to Improve Uptake, Equity, and Newborn Outcomes

Pfizer, in collaboration with the Society for Maternal-Fetal Medicine (SMFM), is pleased to announce a competitive grant opportunity to support independent Quality Improvement (QI) initiatives focused on advancing maternal immunization, with a specific emphasis on Respiratory Syncytial Virus (RSV) vaccination during pregnancy.

This initiative builds upon insights generated from the Maternal Immunization Needs Assessment (MINA) project, a multi-stakeholder collaboration that identified persistent clinical, behavioral, and system-level gaps in the delivery and uptake of maternal vaccines.

We seek to fund projects that implement measurable, evidence-based interventions to improve real-world delivery of maternal RSV immunization across healthcare systems and care settings. Proposed initiatives should aim to optimize access, strengthen provider–patient communication training and tools, enhance care coordination, and address structural and behavioral barriers impacting vaccine uptake and equity.

Pfizer Global Medical Grants (GMG) supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies. Pfizer’s GMG competitive grant program involves a publicly posted Request for Proposal (RFP) that provides detail regarding a specific area of interest, sets timelines for review and approval, and uses an expert review panel (ERP) to make final grant decisions. Organizations are invited to submit an application addressing the specific gaps in clinical practice or care as outlined in the specific RFP.

For all QI grants, the applicant (and ultimately the grantee) will be solely responsible for the design, implementation, and conduct of the proposed initiative. Pfizer will have no involvement in project development, execution, or outcomes.

About the ASHFoundation

ASHFoundation supports innovators and sparks innovation in communication sciences. We give early support to promising students, researchers, and clinicians exploring bold ideas to transform the field and improve people's lives.

Frank R. Kleffner Lifetime Clinical Career Award

The Frank R. Kleffner Lifetime Clinical Career Award recognizes an individual’s outstanding contributions to communication sciences and disorders over a period of at least 20 years. The lifetime contribution may have been in clinical service, supervision or administration of clinical service, clinical research, or any other activity that has promoted clinical excellence.

The award is given in honor of Frank R. Kleffner, a former ASHFoundation president and former ASHA president, who worked tirelessly over his lifetime until his passing in 2015 to professionalize and expand the ASHFoundation’s charitable goals.

The awardee receives a commemorative art object with a recognition plaque.

Purpose

This call for proposals (CFP) provides support to health equity research centers at MSIs to strengthen research infrastructure and capacity-building. Capacity-building will help develop staff, skills, culture, resources, and systems that enable research to happen effectively. Specific work that RWJF may fund under this CFP includes specific skill or methodology training; faculty release time; support for research assistants, advisors, and project staffing; mentoring, professional development and collaboration, and more.

Through this CFP, RWJF will expand its efforts to transform deeply rooted beliefs about which data and research methods are valued, whose perspectives are prioritized, and which populations deserve resources. By supporting the infrastructure and capacity-building needs of MSIs, this opportunity strengthens their ability to generate critical evidence and to cultivate transformative, actionable solutions toward health equity. 

RWJF believes in health equity research that is grounded in systems thinking; supports and disseminates evidence identifying and implementing structural solutions to racial and health inequities. This CFP seeks mission-aligned institutions to participate in cohort-style peer learning to advance their ability to engage in health equity research and apply for competitive funding opportunities in the future.

Although no single philanthropy can fill the gap left by federal funding cuts, this CFP demonstrates strong support for research, historically underrepresented researchers, and research centers that are positioned to pave the way toward a future where health is not a privilege, but a right.

Total Awards

• Type of Award: Awards funded under this opportunity will be structured as grants. 
• Number of Awards: Up to eight awards will be funded. 
• Amount of Award: Each award will be up to and including $350,000.
• Award Duration: Awards will be 24 months.  

Mary Kay Ash Foundation

Guided by Mary Kay Ash’s dream to enrich the lives of women everywhere, the Mary Kay Ash Foundation® raises and distributes funds to invest in breakthrough cancer research and clinical trials to find a cure for women-related cancers and ending domestic violence.

Since 1996, the Mary Kay Ash Foundation®, a 501(c)3 organization, has contributed more than $100 million to organizations aligned with its two-fold mission. In addition, the Foundation supports awareness initiatives, community outreach programs, and advocates for legislation to ensure women are healthy and safe. Through our global charitable foundations in Brazil, Canada, China and the United States, we are collectively making a deeper impact on the lives of women around the world.

Mary Kay Ash Foundation: Cancer Research Grant

The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.

Grant proposals are reviewed by a Scientific Research Review Committee comprised of notable members of the American medical and scientific community. Grants are awarded up to $100,000 (combined direct and indirect costs) for a two-year period. The Foundation anticipates funding between 10 and 15 grants annually. 

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.