Best Grants for Grassroots Organizations in American Samoa

The HEAL Initiative aims to develop non-addictive therapeutics for pain management through small molecules and biologics. This funding opportunity supports preclinical optimization, facilitating the transition of promising candidates to clinical trials. Important proposal deadlines span from January 2024 to January 2027, with optional Letters of Intent encouraged 30 days prior. The program emphasizes collaboration with NIH staff to ensure thorough project planning and monitoring, aiming to revolutionize pain treatment while ensuring safety and efficacy.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Hepatitis C (HepC) Health Equity Fund

Help with healthcare costs for hepatitis C (health equity)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type III (MPS III) Fund

Help with healthcare costs for mucopolysaccharidosis type III

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The BK℠ Scholars Program, administered by the Burger King Foundation, provides substantial scholarships to support high school seniors and restaurant team members in their pursuit of education. With awards ranging from $1,000 to $60,000, the program focuses on academic merit, community service, and financial need. The Foundation emphasizes empowerment through education, ensuring students can access opportunities that foster personal and community growth. This initiative not only honors co-founder James W. McLamore's legacy but also aims to expand educational access across North America.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Fund

Help with healthcare costs for mucopolysaccharidosis type VII

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The NIH Career Transition Award (K22) supports exceptional basic and clinical investigators in developing independent research skills through a two-phase program: an intramural appointment at NIH followed by support at an extramural institution. This award specifically aids NINDS intramural neurologist and neurosurgeon scientists in transitioning to independent academic faculty roles, fostering the engagement of clinician-scientists in both funded scientific research and clinical practices.

The BK℠ Scholars Program, initiated by the Burger King Foundation, provides scholarships ranging from $1,000 to $60,000 to support high school seniors, restaurant team members, and their dependents in pursuing post-secondary education. Established in 2000, the program aims to empower individuals through education, encouraging leadership and civic engagement while also offering emergency assistance to employees facing hardships. This initiative reflects the Foundation's commitment to education and community empowerment across North America.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Acute Myeloid Leukemia (AML) Fund

Help with healthcare costs for acute myeloid leukemia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The Advancing Research Careers (ARC) Predoctoral to Postdoctoral Transition Award (F99/K00) supports late-stage graduate students from diverse backgrounds in transitioning to postdoctoral positions. This phased award aims to facilitate doctoral dissertation completion and subsequent career development in biomedical research. Participants will engage in mentoring, networking, and professional development activities, preparing them for impactful careers that often require postdoctoral training. Key deadlines for applications span from February 2025 to January 2028.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Health Equity Fund

Help with healthcare costs for mucopolysaccharidosis type VII (health equity)

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The National Cancer Institute invites applications for the validation of biomarkers and assays for cancer detection and treatment. This funding opportunity supports both analytical and clinical validation of assays, emphasizing the importance of human samples. The program encourages multi-disciplinary collaboration and aims to enhance the performance and reproducibility of cancer assays across clinical laboratories. Applications are due by 5:00 PM local time during the designated deadlines each year.

The Equitable Excellence Scholarship® Program, administered by Scholarship America, provides 100 annual scholarships of $5,000 to high school seniors with financial need. This program aims to support students as they pursue higher education, with scholarships renewable for up to four years, totaling $20,000 per recipient. Eligible applicants must demonstrate ambition and reside in the U.S. This initiative promotes educational access and equity, celebrating 23 years of empowering students to achieve their dreams.

The NIH Career Transition Award (K22) aims to support outstanding clinician-scientists in developing independent research skills. This grant facilitates a two-phase program, starting with an intramural appointment at the NIH followed by support at an extramural institution. Designed for NINDS intramural neurologist- and neurosurgeon-scientists, it helps them transition to independent academic faculty roles, enabling them to engage in funded scientific research alongside clinical activities.

The CDC's NCIPC invites research proposals to evaluate innovative approaches for preventing firearm-related violence and injuries. This initiative emphasizes the importance of data-driven solutions without infringing on legal firearm ownership rights. Funding options are available for existing data evaluations (up to $350,000/year for 2 years) or new data collection (up to $650,000/year for 3 years). Target areas include mass shootings, suicides, and crime prevention across various demographics and settings.

The NCI CURE Mentored Clinical Scientist Research Career Development Award (K08) aims to support individuals with clinical doctoral degrees in developing research careers that address national health-related needs. This program focuses on enhancing the research capabilities of underrepresented clinical scientists in cancer research, including health disparities. Awardees receive protected time for supervised research training, preparing them to compete for future research project grants. Key deadlines for applications span from February 2025 to October 2027.

The National Human Genome Research Institute (NHGRI) is launching a funding opportunity for the ancient DNA for Modern Genomics (aDMG) program. This initiative aims to create an ethical resource of ancient human DNA to enhance understanding of modern human traits and health. By leveraging both existing and new aDNA data, the program seeks innovative collaborations that integrate ancient and contemporary genomic information. Researchers with expertise in population genomics are encouraged to apply.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Chronic Lymphocytic Leukemia (CLL) Fund

Help with healthcare costs for chronic lymphocytic leukemia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See Approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The Kids to Parks Day School Grants Program offers funding up to $1,000 for Title I schools in the U.S. to enhance student engagement with parks and public lands. This initiative encourages hands-on learning experiences through outdoor activities and stewardship projects, promoting environmental education and healthy lifestyles. Eligible classrooms can apply, emphasizing student involvement in the application process. The program aims to empower students and teachers to foster a deeper connection with nature and their communities.

The Mentored Clinical Scientist Research Career Development Award (K08) supports individuals with clinical doctoral degrees to pursue intensive research training. This program focuses on developing skills in biomedical and behavioral research, addressing national health-related research needs. Key deadlines for applications span from June 2024 to February 2027, with specific dates for standard, renewal, and AIDS-related grants, ensuring that qualified candidates have ample opportunity to apply and advance their research careers.

The Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) program aims to enhance diversity in research by supporting early career investigators from underrepresented backgrounds. This initiative offers a K99/R00 career transition award for postdoctoral scholars and a UE5 cooperative agreement that provides mentorship and professional development. The program's goal is to ensure successful transitions into independent, tenure-track faculty roles in NIH mission areas, ultimately fostering a more inclusive scientific community.

The Research Opportunities for New and At-Risk Investigators (R01 Clinical Trial Optional) program invites applications that promote workforce diversity in health-related sciences. This initiative encourages researchers from underrepresented backgrounds to propose independent research projects in alignment with NIH's mission. Important deadlines for standard and renewal applications range from February 2025 to November 2027. This effort aims to enhance diversity and inclusion within the scientific community.

The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) aims to support mid-career health professionals in conducting patient-oriented research while mentoring clinical residents and junior faculty. This grant offers protected time for research, ensuring participants can focus on impactful studies and foster the next generation of clinical researchers. Key deadlines for applications range from June 2024 to February 2027, with specific dates for standard, renewal, and AIDS-related submissions.

The NIH Mentored Research Scientist Development Award (K01) aims to support early-career researchers in the biomedical, behavioral, or clinical sciences. This program provides three to five years of protected time for intensive career development, paving the way to research independence. Various NIH Institutes leverage this award to assist individuals transitioning into new fields or re-engaging with research after personal challenges. The K01 is a vital resource for cultivating the next generation of scientific leaders.

The NIH Pathway to Independence Award (K99/R00) aims to enhance the career development of promising postdoctoral researchers by transitioning them into independent faculty positions. This program supports innovative research during the critical transition phase, enabling awardees to establish successful, independent research careers. Key application deadlines span from June 2024 to February 2027, with specific dates for standard, renewal, and AIDS-related applications. This initiative is vital for fostering a new generation of NIH-supported investigators.

The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) supports mid-career health professionals by providing protected time for patient-oriented research and mentorship to clinical residents, fellows, and junior faculty. The program aims to enhance research capabilities and promote career development in the field of patient-oriented research. Key deadlines for applications include June 12, 2024, and October 12, 2024, among others, ensuring opportunities for renewal and resubmission.

The NIH Pathway to Independence Award (K99/R00) program is designed to support promising postdoctoral researchers in transitioning to independent faculty positions. This initiative aims to maintain a strong cohort of talented investigators by providing independent NIH research funding during this critical phase. Key application deadlines span from June 2024 to February 2027, encouraging applications from diverse fields, including AIDS-related research.

The Procter & Gamble U.S. Large Site Community Grant supports initiatives that enhance the lives of individuals within 50 miles of P&G facilities. Focused on areas like infant development and hygiene, this competitive grant seeks to partner with organizations aligned with its mission. Interested groups should verify eligibility through the P&G grant portal. While many applications are received, only a select few will be funded due to high demand.