Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed) (358082)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
This funding opportunity invites innovative pilot studies focused on biological, behavioral, and social mechanisms related to HIV pathogenesis, aligning with NIDDK's mission and NIH HIV/AIDS research priorities. Topics may include exploring pathophysiological mechanisms of HIV comorbidities and coinfections, understanding HIV reservoirs in relevant tissues, and examining social determinants affecting health outcomes. Applications are due by 5:00 PM local time of the applicant organization.
HIV / AIDS
Diabetes
Kidney Diseases
+1 more
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) (358090)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The HEAL Initiative: Pain Research Enhancement Program (PREP) aims to support R15-eligible Principal Investigators in conducting rigorous pain research. This initiative promotes interdisciplinary partnerships and enhances the research environment for health professional trainees. Key deadlines include October 28, 2025, and October 27, 2026, for standard applications, and November 24, 2025, and November 23, 2026, for AIDS-related applications. Letters of Intent are encouraged 30 days prior to the due date.
Chronic / Acute Pain
Anesthesia and Pain Medicine
REPI Challenge
United States Department of Defense (DOD)
Federal Government
American Samoa, Guam +4 more
Up to US $20,000,000
The REPI Challenge, initiated by the DOD's REPI Program, aims to protect critical testing and training capabilities through funded projects. Since 2012, over $193 million has been allocated to 69 initiatives, leveraging more than $512 million in partner contributions. The upcoming 2026 REPI Challenge will focus on strategic mission safeguarding, with up to $20 million available for preventing land use conflicts and enhancing military resilience, thus ensuring the longevity of vital defense capabilities.
Environmental Conservation
Habitat & Ecosystem Restoration
Land / Habitat Conservation
+8 more
Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional) (358116)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The Limited Competition Small Grant Program for NIDDK K01/K08/K23/K25 recipients offers funding opportunities for pilot studies and feasibility research. This program aims to support researchers transitioning to independent investigator roles by providing resources for small projects that can yield preliminary data for future R01 applications. Key deadlines for applications range from February 2025 through January 2028, with specific dates for standard, renewal, and AIDS-related applications.
Diabetes
Kidney Diseases
Digestive System Health & Diseases
Ryan White HIV/AIDS Program Part D - Women, Infants, Children and Youth Grant Supplemental Funding (363415)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.
HIV / AIDS
Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.
HIV / AIDS
Fetal, Infant, and Child Death Review Program
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $5,149,000
The Fetal, Infant, and Child Death Review Program aims to enhance the effectiveness of fetal, infant, and child death review teams across state, local, and tribal levels. By providing essential leadership and technical assistance, the program ensures standardized practices for conducting quality fatality reviews and collecting vital data. These efforts will facilitate the dissemination of findings, ultimately informing prevention strategies and improving outcomes for vulnerable populations.
Maternal And Perinatal Health
State Maternal Health Innovation Program (SMHI)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $657,142 - US $1,000,000
The State Maternal Health Innovation Program (SMHI) aims to enhance maternal health across states by addressing critical gaps. It focuses on improving service quality, developing a skilled workforce, and utilizing enhanced data capabilities. Through innovative programming, the initiative strives to significantly reduce maternal mortality and severe maternal morbidity, ensuring better health outcomes for mothers and their families.
Women's Health
Maternal And Perinatal Health
Maternal and Child Health (MCH) Nutrition Training Program (363411)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
US $550,000 - US $735,000
The Maternal and Child Health (MCH) Nutrition Training Program aims to enhance the nutrition and overall health of mothers and children. This initiative focuses on interdisciplinary graduate education, equipping a skilled workforce to support Title V and other MCH programs. It seeks to expand nutrition education and career pathways while improving access to quality nutrition services. Trainees will gain practical experience through placements at health centers, ultimately benefiting families and communities.
Maternal And Perinatal Health
Nutrition & Healthy Eating
Leadership Education in Adolescent Health (LEAH) (363410)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
US $400,000 - US $459,370
The Leadership Education in Adolescent Health (LEAH) Program, funded by the US HHS: Health Resources & Services Administration, aims to enhance the quality of care for adolescents and young adults. By establishing graduate training programs, LEAH prepares healthcare professionals to effectively address chronic disease prevention and improve access to team-based healthcare services for this population, ultimately fostering better health outcomes and empowering future leaders in adolescent health.
Health & Medicine
Medical Education & Professional Training
Fiscal Year (FY) Service Area Competition (SAC)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $566,100 - US $15,336,000
The FY 2027 Service Area Competition (SAC) funding aims to enhance healthcare access in underserved communities across the U.S. by providing grants for comprehensive primary and preventive health services. This initiative addresses essential health needs through competitive funding opportunities, ensuring that health centers can effectively serve their designated areas. Additional service areas may be announced as needed if current centers are unable to continue their operations, thus maintaining service continuity.
Health & Medicine
Health Care Access & Delivery
Fiscal Year (FY) 2027 Service Area Competition (SAC)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $650,000 - US $10,117,000
The FY 2027 Service Area Competition (SAC) aims to enhance health services in underserved communities across the U.S. and its territories. This funding opportunity supports comprehensive preventive and primary health care delivery. Each SAC announcement details service areas available for competition, with potential additional areas announced throughout the year. This initiative is crucial for ensuring continuous access to quality health care for vulnerable populations.
Health & Medicine
Health Care Access & Delivery
Fiscal Year (FY) 2027 Service Area Competition (SAC) (363423)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $1,216,000 - US $19,182,000
The FY 2027 Service Area Competition (SAC) aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive primary and preventive care. This initiative will support health centers in delivering high-quality services, addressing the needs of populations that face barriers to care. Each funding opportunity will specify service areas available for competition, ensuring effective resource allocation to improve community health outcomes.
Health & Medicine
Health Care Access & Delivery
World Trade Center Youth Research Coordinating Center (U54)
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $10,000,000
The World Trade Center Youth Research Coordinating Center aims to establish a research cohort to study the health impacts on youth exposed to the 9/11 events. This initiative, backed by the NIOSH, will focus on individuals aged 21 or younger at the time of exposure, including those in utero. The Center will integrate diverse expertise to assess long-term health and educational effects while enhancing community engagement and stakeholder communication throughout its activities.
Occupational Health & Safety
Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The R01 grant program aims to address disparities in liver diseases and liver cancer in the United States. It supports multi-level intervention research targeting populations with significant health disparities. With deadlines spanning from February 2024 to June 2027, this initiative encourages innovative approaches to improve health outcomes in underserved communities, ultimately enhancing public health and reducing inequities in healthcare access and treatment.
Cancer / Oncology
Digestive System Health & Diseases
Health Disparities & Social Determinants of Health
+1 more
Fiscal Year (FY) 2027 Service Area Competition (SAC) (363419)
US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $398,400 - US $22,025,000
The FY 2027 Service Area Competition (SAC) funding aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive preventive and primary health care. The initiative supports health centers in delivering essential services, ensuring that vulnerable populations receive the care they need. Service areas for competition are announced periodically, and additional areas may be added if existing centers are unable to continue their services.
Health & Medicine
Health Care Access & Delivery
State Occupational Safety and Health Surveillance Program (U60) (363431)
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $150,000 - US $685,000
The State Occupational Safety and Health Surveillance Program (U60) aims to enhance state-level occupational safety and health (OSH) surveillance capacity. Funded by NIOSH, this initiative supports various state programs, fostering partnerships among health departments and universities. By utilizing diverse data sources, these programs assess workplace health impacts and develop tailored interventions, ultimately ensuring better health and safety for workers across the U.S. This collaborative approach addresses critical gaps left by regulatory programs.
Occupational Health & Safety
HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $350,000 - US $750,000
The HEAL Initiative aims to combat the opioid crisis through action-oriented research that enhances the translation of addiction epidemiology, prevention, treatment, and recovery services into practice. It prioritizes scalable, evidence-based approaches targeting various levels, including individual and community. The initiative supports a range of methods for research deployment, emphasizing collaboration between researchers and decision-makers to improve outcomes for those affected by addiction and related chronic pain.
Epidemiology & Public Health
Addiction & Substance Use Disorders
Drug Use Disorder
+2 more
NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34 Clinical Trial Optional) (351692)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34) aims to support high-risk, multi-center clinical studies by facilitating early peer review and assessment of study designs. This program helps in the development of necessary operational documents and essential elements for conducting hypothesis-driven studies focused on diseases relevant to NIDDK. Applications are due by 5:00 PM local time, and consulting with NIDDK staff is strongly encouraged.
Diseases & Conditions
Digestive System Health & Diseases
Kidney Diseases
+1 more
The Climate Smart Communities Initiative (CSCI) Grant
Climate Resilience Fund
Private
American Samoa, Guam +4 more
US $75,000 - US $115,000
The Climate Smart Communities Initiative (CSCI) Grant supports US-based projects aimed at enhancing community resilience against climate change. With a budget of $1.5-2 million, grants typically range from $75,000 to $115,000. CSCI prioritizes projects that focus on historically disinvested populations facing climate vulnerabilities, emphasizing equity, nature-based solutions, and community capacity building. The initiative encourages collaboration between climate adaptation practitioners and local government entities to address climate impacts effectively.
Climate Change Resilience & Equity
Recordings at Risk Grant
Council on Library and Information Resources (CLIR)
Private
American Samoa, Guam +4 more
US $10,000 - US $50,000
The Recordings at Risk Grant, administered by CLIR, supports the preservation of rare audio and audiovisual media of scholarly value through digital reformatting. With funding from The Andrew W. Mellon Foundation, the program aims to award $6.75 million across twelve competitions, offering grants between $10,000 and $50,000. It encourages U.S. nonprofit institutions to preserve vulnerable media, helping them to develop strategies for effective digital reformatting and promoting best preservation practices.
Historical Records & Archives
Powering Affordable Reliable Technology (PART) Energy Program
Rural Utilities Service
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $100,000,000
The Powering Affordable Reliable Technology (PART) Energy Program, managed by the Rural Utilities Service, seeks Letters of Interest for loan applications to fund renewable energy generation and energy storage projects. With approximately $410 million available from the Inflation Reduction Act, the program offers up to 75% financing for project costs, along with potential loan forgiveness options. This initiative aims to enhance energy infrastructure in rural areas, promoting sustainable energy solutions.
Rural Development
Emerging Technology Development
Emerging or Other Renewable Energy Sources
Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The National Institute of Dental and Craniofacial Research (NIDCR) is inviting innovative research applications on the causal relationships between human behaviors and oral-systemic health impacts, particularly for people with chronic conditions. This funding opportunity encourages the exploration of biological, environmental, and psychosocial factors contributing to health outcomes. Projects should aim for translation into clinical trials to manage dental and craniofacial conditions effectively. Collaboration among diverse health experts is strongly encouraged.
Cognitive Science
Psychology
EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows
National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows program, funded by the National Science Foundation (NSF), aims to enhance research capacity and workforce development in STEM. This initiative fosters collaborations between underrepresented researchers and leading institutions, providing essential resources and support. With two tracks available—one focusing on NSF and the other on NASA—this program uniquely positions Fellows to leverage transformative research experiences and contribute to sustainable advancements in their respective fields.
Economics
Sociology
Mathematics
+10 more
Trans Justice Funding Project Grants
Trans Justice Funding Project
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Trans Justice Funding Project (TJFP) provides grants to grassroots trans-led organizations in the U.S. and territories, focusing on those with budgets under $250,000. TJFP supports initiatives that address varying needs within trans communities, including health, legal aid, and mutual aid projects. The organization prioritizes groups led by trans people of color and emphasizes the importance of centering marginalized voices in the fight for trans justice.
Intersex & Transgender Rights
Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76 Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Paul B. Beeson Emerging Leaders Career Development Award in Aging is designed for early-stage physicians and health professionals committed to aging research. This initiative, supported by the NIH, aims to cultivate leadership skills and advance research in geriatrics. Eligible candidates must demonstrate prior research support and leadership in their field. While applications are not currently being accepted, this NOFO encourages potential applicants to develop collaborative and impactful projects in aging research.
Aging / Gerontology
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) (358375)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Intervention Research to Improve Native American Health initiative aims to enhance health outcomes in Native American communities through innovative research. This program supports studies focused on health promotion, disease prevention, and culturally informed treatment strategies. Key deadlines for grant applications are October 21, 2025, and January 7, 2026. By addressing health disparities and leveraging community strengths, the initiative fosters sustainable interventions tailored to specific cultural contexts.
Indigenous Health Systems
Native American Services
Health Disparities & Social Determinants of Health