Best Private Grants for Nonprofits in American Samoa

The DoW Ovarian Cancer Clinical Trial Award, funded by the U.S. Army Medical Command, aims to accelerate the implementation of clinical trials that significantly impact ovarian cancer treatment. This award supports diverse trial designs, from early proof-of-concept studies to large-scale efficacy trials, evaluating innovative drugs, biologics, and technologies. By fostering research in this critical area, the program seeks to enhance patient outcomes and advance the understanding of ovarian cancer management.

The DoW Prostate Cancer Data Science Award supports innovative research using analytical approaches to analyze complex prostate cancer data. It covers areas such as bioinformatics, machine learning, and medical imaging, addressing significant challenges in prostate cancer research. This award allows multiple Principal Investigators, enhancing collaboration. Only the lead PI submits a pre-application, while all PIs must submit comprehensive applications. If any application is rejected, all related submissions may be withdrawn, ensuring a cohesive research effort.

The DoW Prostate Cancer Idea Development Award for fiscal year 2026 supports innovative research ideas that address the Prostate Cancer Research Program's overarching challenges. This award emphasizes new investigators within 10 years of their terminal degree, encouraging collaboration with experienced researchers in the field. By fostering unique approaches to prostate cancer research, the program aims to make significant contributions to advancing understanding and treatment of this disease.

The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 3 supports transformative research aimed at significant advancements in breast cancer treatment. Applicants must address key challenges outlined by the program, ensuring their proposals demonstrate potential for impactful breakthroughs. This funding mechanism, which permits small-scale clinical trials, emphasizes collaboration by requiring research teams to include two breast cancer consumer advocates and allows for a single Principal Investigator or two partnering PIs.

The National Institute on Aging (NIA) is preparing to publish a Notice of Funding Opportunity (NOFO) aimed at advancing research on the genomic factors influencing Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD). This initiative encourages interdisciplinary projects that utilize innovative genomic analysis techniques to uncover the mechanisms of neurodegeneration. The goal is to identify therapeutic targets that can inform precision medicine strategies for AD/ADRD treatment, while allowing time for potential applicants to form collaborations.

The National Institutes on Deafness and other Communication Disorders (NIDCD) is inviting applications for a Coordinating Center for the National Human Ear Resource Network. This initiative aims to enhance research on auditory and vestibular disorders by providing essential resources, facilitating collaboration among laboratories, and promoting the use of human ear tissues in studies. The Center will play a pivotal role in coordinating activities, sharing updates with the scientific community, and supporting various research efforts across the nation.

The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.

The Maternal and Child Health Encounters Networks (MCHEK) program, funded by the US HHS: Health Resources & Services Administration, aims to enhance maternal and infant health by preventing exposure to harmful substances throughout pregnancy. Through a national expert call center, it provides evidence-based guidance on medications, nutrition, and environmental factors. By translating complex scientific data into accessible information, MCHEK empowers families and healthcare providers to make informed choices that improve health outcomes.

The Asian Cultural Council's New York Fellowship offers a transformative six-month program for artists, scholars, and arts professionals from Asia. Participants engage deeply with New York City's vibrant cultural landscape, attending performances, exhibitions, and workshops while building networks with local communities. This unique opportunity fosters peer-learning and individual artistic development, encouraging fellows to incorporate their experiences into their practices and contribute to their home cultures. The fellowship emphasizes exploration, exchange, and support, culminating in a rich cultural immersion.

The Climate Smart Communities Initiative (CSCI) Grant supports US-based projects aimed at enhancing community resilience against climate change. With a budget of $1.5-2 million, grants typically range from $75,000 to $115,000. CSCI prioritizes projects that focus on historically disinvested populations facing climate vulnerabilities, emphasizing equity, nature-based solutions, and community capacity building. The initiative encourages collaboration between climate adaptation practitioners and local government entities to address climate impacts effectively.

The FY26 Bus Safety, Accessibility, and Innovation Notice of Funding Opportunity offers up to $10 million for innovative projects aimed at enhancing bus safety and accessibility. Administered by the Federal Transit Administration, this competitive grant invites applications for the development of concepts that improve safety for operators and vulnerable road users, ensuring that public transportation is safer and more accessible for all passengers.

The Fetal, Infant, and Child Death Review Program aims to enhance the effectiveness of fetal, infant, and child death review teams across state, local, and tribal levels. By providing essential leadership and technical assistance, the program ensures standardized practices for conducting quality fatality reviews and collecting vital data. These efforts will facilitate the dissemination of findings, ultimately informing prevention strategies and improving outcomes for vulnerable populations.

The Federal Transit Administration (FTA) is offering approximately $589 million in competitive grants through the Low or No Emission Grant Program. These funds support the purchase or lease of low-emission and zero-emission transit buses, along with the construction and leasing of necessary facilities. This initiative aims to enhance sustainable public transportation solutions. Further details and the full announcement will be available on Grants.gov under opportunity FTA-2026-011-TPM-LWNO.

The Lung Cancer Translational Research Award (TRA) for FY26 supports innovative translational research aimed at transforming promising lung cancer ideas into clinical applications. This award emphasizes advanced preclinical studies and pilot clinical trials of novel interventions, addressing critical research areas within the Lung Cancer Research Program. Applicants can choose between two funding levels to advance their impactful studies, thereby contributing to significant advancements in lung cancer treatment.

The Ovarian Cancer Clinical Trial Academy (OCCTA) supports Early-Career Investigators (ECIs) in clinical trial research aimed at effective ovarian cancer treatments. It provides essential mentoring, networking, and skill development needed for executing clinical trials. The FY26 funding will specifically support translational research and early-phase trials, requiring preliminary data and a commitment of at least 25% effort from the ECI. Mentorship is vital, with a focus on experienced clinical trialists guiding ECIs.

The Lung Cancer Patient-Centered Outcomes and Survivorship Award (PCOSA) aims to enhance health outcomes for lung cancer patients by promoting patient-centered research. This FY26 initiative encourages projects that address key areas of survivorship and requires the involvement of lung cancer survivors or caregivers in research teams. Additionally, it supports both translational and clinical research, including pilot clinical trials, to improve the overall patient experience.

LSC’s Basic Field Grants aim to enhance access to civil legal services for low-income individuals across the U.S. and territories. These grants support eligible organizations for up to three years through a competitive application process. The funding is allocated to specific service areas, which change annually, and focuses on providing comprehensive legal assistance. The program includes three types of service areas, ensuring diverse populations, including agricultural and Native American communities, receive necessary legal support.

The Statewide Perinatal Quality Collaboratives initiative aims to enhance the health of pregnant and postpartum women and their newborns through quality improvement strategies. Funded by the CDC, the program encompasses two components: state-based Perinatal Quality Collaboratives and a National Network coordinating center. Key strategies include strengthening data systems and fostering partnerships to improve healthcare services and outcomes. Ultimately, this initiative seeks to implement successful quality improvement initiatives that ensure better coordination and health outcomes for mothers and newborns across the United States.

The FY26 Lung Cancer Research Program's Idea Development Award supports innovative, high-risk research aimed at significant breakthroughs in lung cancer treatment. It encourages new concepts in their early stages, requiring preliminary data to demonstrate feasibility, although not necessarily from lung cancer studies. This program also features a New Investigator category, allowing early-career researchers to compete separately for funding, fostering a diverse range of impactful investigations.

The OVW Fiscal Year 2026 Training and Services to End Abuse in Later Life Program aims to provide essential resources to combat abuse against individuals aged 50 and older. Funded by the US DOJ's Office on Violence Against Women, this initiative supports states, Tribal governments, and nonprofit organizations in addressing various forms of abuse, including domestic violence, sexual assault, and economic exploitation. Applications are due by September 16, 2026, ensuring timely assistance to vulnerable populations.

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.

The FY26 Prostate Cancer Research Program (PCRP) Physician Research Award supports early-career clinician investigators in their transition to prostate cancer research. Applicants must include a mentor with relevant experience and outline a personalized development plan aimed at acquiring essential research skills. The award encourages innovative approaches to addressing the program's overarching challenges, ultimately enhancing the career trajectories of participating physicians in this critical field.

The NINDS Faculty Development Award aims to enhance diversity in neuroscience research by supporting junior faculty from underrepresented backgrounds. This award provides essential research cost support, protected research time, and mentorship for individuals holding doctoral degrees within their first three years on a faculty tenure track. It specifically encourages research proposals that do not involve independent clinical trials, while allowing participation in trials led by mentors. Key application deadlines span from October 2024 to June 2027.

The National Institute of Neurological Disorders and Stroke (NINDS) aims to support innovative research for validating therapeutic targets in Alzheimer's Disease-Related Dementias (ADRD). This initiative focuses on overcoming barriers in treatment development by ensuring well-validated targets linked to disease mechanisms. By employing a phased award mechanism, NINDS seeks to enhance the rigor of target validation, facilitating the transition from basic discoveries to clinical applications, ultimately accelerating the development of effective therapeutic strategies.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.

The DoW Military Burn, Patient-Centered Research Award aims to enhance the implementation of burn care research into clinical practice for military settings. The FY26 program supports clinical trials and research that directly benefit burn patients in resource-limited environments, fostering collaborations between experienced researchers and junior scholars. This initiative addresses critical gaps in combat burn care, ensuring effective interventions and guidelines are developed and utilized in operational battlespaces.

The Scholarship America Dream Award, established by Scholarship America Inc, aims to eliminate financial barriers to higher education for students. This program supports U.S. citizens, permanent residents, and DACA recipients, who are at least 17 years old and pursuing their first degree with a minimum GPA of 3.0. By partnering with various organizations, Scholarship America has provided over $5.7 billion in scholarships to millions, ensuring equitable access to education and fostering student success.