Best Seed Grants for Nonprofits in American Samoa

The National Institute of Environmental Health Sciences (NIEHS) is seeking applications for research coordination and data support under the Health and Extreme Weather initiative. This funding opportunity aims to engage NIH grantees and the broader community by sharing best practices, developing training resources, and facilitating access to health and environmental data. The initiative will enhance collaboration, reduce duplication, and promote data standards to support impactful research and infrastructure activities.

The NIH Pathway to Independence Award (K99/R00) supports the transition of postdoctoral researchers to independent faculty positions. It aims to enhance the number of talented NIH-supported investigators by providing funding during their transition to independent research careers. Key deadlines for applications are set for various dates through 2027. This program is crucial for developing a strong cohort of new independent researchers, fostering innovation in health-related fields.

The NIH Pathway to Independence Award (K99/R00) promotes the development of new independent investigators by facilitating their transition from mentored postdoctoral positions to independent faculty roles. This award supports their research efforts, ensuring they have the necessary resources to establish competitive research careers. Important application deadlines span from June 2024 to February 2027, covering standard, renewal, and AIDS-related applications, aimed at enhancing innovation and research capabilities in biomedical fields.

The NIH Mentored Research Scientist Development Award (K01) provides crucial support for early-career researchers in the biomedical, behavioral, or clinical sciences. This award offers three to five years of protected time for intensive, supervised career development, fostering research independence. It is particularly beneficial for those transitioning into new fields or resuming their careers after significant interruptions due to personal circumstances. Various NIH Institutes utilize the K01 to enhance research capabilities across diverse disciplines.

This grant opportunity invites R01 applications aimed at fostering diversity in the research workforce by supporting New and At-Risk Investigators from underrepresented backgrounds in health-related sciences. The program is aligned with the mission of the participating NIH Institutes and Centers and seeks to promote independent, innovative research projects. Applications are due on specific dates throughout 2025-2027, with a focus on enhancing diversity in scientific research.

The OJJDP FY 2026 Juvenile Justice System Enhancements program aims to bolster the effectiveness of juvenile justice systems across the nation. By targeting high-cost drivers of crime and enhancing youth outcomes, this initiative encourages states and localities to develop strategic solutions. Applicants are invited to identify challenges within their systems and prioritize resource allocation for measurable improvements, ultimately aiming to prevent crime and improve operations within the juvenile justice framework.

The HFM Foodservice Scholarship Fund supports students in Hawaii pursuing education in Culinary Arts or Agriculture. Applicants must demonstrate financial need, maintain a minimum GPA of 2.7, and attend an accredited institution in the U.S. Preference is given to prior recipients in good academic standing. This scholarship aims to empower future leaders in the foodservice industry by providing financial assistance to deserving candidates.

The Rehabilitation Engineering Research Center on Recreational, Sport, and Exercise Technologies for People with Disabilities aims to enhance rehabilitation services through innovative technological solutions. This initiative focuses on promoting health and exercise among individuals with disabilities by addressing unique rehabilitation challenges. Funded by the US HHS Administration for Community Living, the project spans 60 months, involving advanced research and development to create effective support mechanisms and overcome environmental barriers.

The Jay L. Smith Family Foundation provides grants to tax-exempt non-profit organizations in the United States, primarily focusing on healthcare, family values, and supporting the disadvantaged. With a strong commitment to Alzheimer's research, the foundation has funded various initiatives including elderly care, domestic violence prevention, and cancer research. Their mission is to enhance the quality of life for individuals and communities through meaningful contributions, aiming to address critical social issues and promote well-being.

The Radiation Exposure Screening and Education Program aims to support organizations in their efforts to screen and educate individuals who have been exposed to radiation from uranium mining and U.S. nuclear weapons testing. This initiative emphasizes the importance of awareness and education in mitigating health risks associated with radiation exposure, ensuring affected communities receive the necessary resources and support for health management.

The Innovative Research in Cancer Nanotechnology (IRCN; R01 Clinical Trial Not Allowed) program invites applications focused on revolutionary breakthroughs in cancer biology and oncology through nanotechnology. Projects should tackle significant challenges in these fields while emphasizing mechanistic studies of nanomaterials and devices. The aim is to enhance understanding of their interactions with biological systems, particularly in delivering nanoparticles to cancer targets, thus laying the groundwork for future nanotechnology-based interventions.

The Air Force Fiscal Year 2027 Young Investigator Program (YIP) is designed to support early career scientists and engineers who have recently obtained their Ph.D. This initiative aims to promote innovative basic research in science and engineering while enhancing the professional growth of promising investigators. Awards are available to U.S. institutions where the principal investigator is a full-time employee. Eligible candidates must be U.S. citizens, nationals, or permanent residents.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The NSF Geosciences Core Research program funds innovative projects across atmospheric, geospace, earth, and ocean sciences. It encourages proposals that push the boundaries of knowledge in fundamental research, promoting interdisciplinary approaches. This initiative seeks transformative ideas that may not have immediate commercial applications but are crucial for advancing scientific understanding and addressing complex environmental challenges. Researchers are invited to explore various domains or integrate multiple disciplines to enhance our comprehension of the Earth and its systems.

The National Institutes of Health (NIH) is continuing support for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), which focuses on clinical trials and biomarker validation studies for neurological disorders. This initiative aims to foster innovation in neurotherapeutics by providing essential infrastructure and expertise. The program encourages the establishment of Clinical Coordinating Centers (CCC) and Data Coordinating Centers (DCC) to enhance collaborative efforts. Note that applications are not currently being solicited.

This grant aims to enhance safety and health in U.S. mining operations through research in automation, robotics, and intelligent systems. It addresses critical issues like emergency communication and self-escape reliability while supporting the development of field-ready solutions. By leveraging advanced technologies, the initiative seeks to improve miner safety and health, reduce hazardous exposures, and foster community engagement. Applicants must be U.S. academic institutions with accredited mining programs, linking project goals to documented health burdens.

About

Paul Newman was born and raised in Ohio by parents who owned a successful sporting goods store. He enlisted in the Navy and completed his military service as a radioman/gunner in the Pacific during World War II. Seeing his father’s business ethic during the Great Depression and experiencing the war fueled his desire to help others in need.

In 1958, Paul made his acting debut on Broadway in “Picnic,” where he also met his future wife, Joanne Woodward. Paul started a successful race car driving career inspired by training for the film Winning. He went on to win second place in the 24 Hours of Le Mans, the world’s oldest endurance race event. After years of acting and being recognized for his achievements on screen and stage, he received many accolades including an Oscar for Best Actor in The Color of Money.

Paul used his fame for good. He was dedicated to civil rights–attending the March on Washington in August 1963–women’s rights, and gay rights. He used his platform to advocate for equal pay for his female co-stars. He was a vocal political advocate committed to ending the nuclear arms race and determined to elect opponents of war and militarism. President Jimmy Carter appointed him to a United Nations General Assembly session on nuclear disarmament.

In 1982, Paul Newman and his friend Hotch founded a food company on a bit of a lark. They turned a profit selling salad dressing that first year, and did something truly radical when they decided to “give it all away” to good causes.

Paul established Newman’s Own Foundation to ensure the continuation of his philanthropic legacy after his passing. 40+ years since its founding, his first of its kind food company and its innovative business model are still going strong.

Garden Grants

Through Whole Foods Market’s Garden Grant program, schools turn outdoor spaces into powerful hands-on learning gardens that connect kids with food, spark their curiosity and support classroom curriculum.

The National Urban Indian Health Program aims to enhance behavioral health services for Urban Indian communities by fostering awareness, advocacy, and collaboration across the nation. By providing technical assistance and training to Urban Indian Organizations, the program seeks to improve access to culturally relevant behavioral health care for American Indian and Alaska Native populations residing in urban areas, ultimately leading to better health outcomes and community support.

The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.

The Von Voigtlander Family Foundation Grant, though currently closed, aims to support 501(c)(3) charitable organizations, primarily in Michigan. The foundation emphasizes animal welfare, parks preservation, veteran support, and youth empowerment. Their mission is to enhance lives through community-focused initiatives that foster resilience, education, and well-being. They prioritize charities that promote responsible pet ownership, outdoor recreation, and provide resources for veterans and youth, ensuring a positive impact across multiple sectors.

The Creation & Development Fund, administered by the National Performance Network, supports the creation and mobility of artistic works that promote racial and cultural justice. It fosters collaboration between artists and communities through financial support, enabling artists to develop meaningful relationships and present their work. The fund emphasizes equity, access, and the importance of public engagement, ensuring that diverse voices are represented while addressing systemic injustices in the arts.

The National Cancer Institute (NCI) invites applications for the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program. This funding opportunity focuses on advanced pre-clinical research aimed at developing nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards will support the maturation of innovative nanomedicines using nanoparticles and nano-devices, enhancing cancer treatment efficacy. Successful projects will progress towards further NCI translational programs, such as the NExT initiative.

About Borealis Philanthropy

Borealis Philanthropy is a philanthropic social justice intermediary that works to resource grassroots leaders and social justice movements for transformative change. We help funders expand their reach and strengthen their impact through donor collaboratives that support a variety of issues, communities, and movements. Borealis is home to nine donor collaboratives, including the Disability Inclusion Fund and Disability x Tech.

DIF x Tech Fund

For the Disability Inclusion Fund at Borealis, part of our efforts for disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. The DIF x Tech initiative, supported by the Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest, invites proposals that are working to bring about transformational change at the intersections of disability, justice, and technology

About the Disability Inclusion Fund and DIF x Tech

The Disability Inclusion Fund (DIF) supports U.S.-based groups run by and for people with disabilities to lead transformational change. The Fund is supported by donors including the Presidents’ Council on Disability Inclusion in Philanthropy, which is comprised of foundation presidents who are committed to disability inclusion as part of improving diversity, equity, and inclusion within philanthropy.

Part of the efforts of disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. This newly launched initiative is housed at the Disability Inclusion Fund (DIF) and supported by Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest. 

DIF x Tech Fund Values

All Disability x Tech award decisions will align with the DIF guiding values. The DIF guiding values are:

• Participation: Movement funding accountable to the disability rights movement. Those impacted by injustice/exclusion should be involved in strategies to advance justice/inclusion.
• Intersectionality: Acknowledging that disabled people have multiple and intersecting social and political identities that can influence their ability to have access and inclusion including race, gender identity, class, sexual orientation.
• Radical inclusion: Deeply committed to removing barriers and ensuring access so that those most affected by intersecting identities can participate, valuing lived experience.
• Leadership of those most impacted by ableism: Emphasis is given to organizations led by people subject to systemic bias and impacted by underrepresentation, particularly disabled people of color, queer, gender nonconforming and women with disabilities.
• Cross-movement solidarity: Intentional focus on collaboration and bridge- building amongst disability justice activists and across movements.
• Sustainability: Resources and tools that support the growth of grassroots disabled-led organizations, and expand operational capacities for ongoing movement building. 

What we fund

We invite proposals that are at the nexus of technology, disability rights and justice. This opportunity may be a good fit for your organization, if you are doing work in any of these areas below:

• Disabled people sharing technical skills and knowledge with others in the community.
• Disabled people leading policy, rights, and disability justice activism work related to tech. 
• Disabled people participate in all stages of the design and development of new tech that will enrich lives of people with disabilities.
• Enabling collective and equitable access to digital infrastructure. 
• Expanding the participation, leadership, and thought partnership of overlooked and under-resourced people with disabilities in all areas of the technology sector.
• Partnerships between disability-focused engineering design labs and maker spaces within schools, centers for independent living, or local nonprofit organizations.
• Permissible Policy Work:
  • We may support nonpartisan policy education and advocacy related to disability and technology. Any lobbying must remain within applicable 501(c)(3) limits and Borealis grant restrictions.

The BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA) aims to enhance the capacity of grantees through dedicated training. It addresses critical operational issues related to overdose responses, targeting illicit opioids and stimulants. The program underscores the U.S. Department of Justice's commitment to public safety, law enforcement support, and the fight against substance misuse. Applications are due by November 9, 2026.

Creative West

Established in 1974 as a nonprofit U.S. Regional Arts Organization (USRAO), Creative West was founded on the belief that place matters to the creative process. Fifty years later, communities of place, practice, experience, and identity remain fundamental to our work, framing our understanding of how culture is creatively produced and collectively experienced.

Creative West empowers artists and culture-makers with direct, practical resources, delivered regionally.

We offer practical, equity-centered learning experiences and funding opportunities that connect and inspire artists, culture-bearers and communities to build a more inclusive sector, strengthen the arts field, and catalyze change.

Pacific Jurisdictions Artist Fund

The 2026 Pacific Jurisdictions Artist Fund (PJAF) is a community-rooted, artist-centered fund co-designed with artists and cultural leaders across American Samoa, Guam, and the Commonwealth of the Northern Mariana Islands (CNMI). PJAF honors artists as essential culture bearers — preserving language, lineage, land-based knowledge, and strengthening community wellness and belonging. This year is the second round of the program. There will be one more round of the program in 2027.

This is not a project grant. This is unrestricted support rooted in trust and care.

What’s New for Year Two (2026)

• Flat grant: Exactly $2,000 per awardee
• 15 awards per jurisdiction
• $30,000 allocated per island
• Ambassador pathway for alumni
• Simplified application
• Short informational videos on what to expect and how to apply
• Virtual information sessions and office hours with Creative West
• Opportunities to meet with or connect selected past awardees (Ambassadors) for support

Funding Overview

• Each selected artist receives:
• $2,000 (Without restrictions)

The artist decides how they want to use the funds.

Examples include:

• Time to create or rest
• Tools, materials, or equipment
• Mentorship or training/workshops
• Rent, food, or family care
• Cultural teaching or gatherings
• Wellness or healing

The DOJ FY 2026 ANGEL Grant Program aims to enhance public safety by funding state, local, and tribal government initiatives to combat violent crime committed by criminal illegal aliens. This program supports hiring law enforcement personnel, retaining critical staff, and acquiring advanced technology. The objective is to prevent harm to American citizens and support Homeland Security Task Force operations. Applications must be submitted by October 27, 2026, to qualify for funding.