Best Ascension Parish Grants for Nonprofits in Louisiana

About NIF

Advancing Equality for All Israelis

The New Israel Fund (NIF) helps Israel live up to its founders’ vision of a society that ensures complete equality to all its inhabitants. Our aim is to advance liberal democracy, including freedom of speech and minority rights, and to fight the inequality, injustice and extremism that diminish Israel.

From Israel’s first rape crisis centers, to fighting discrimination, NIF-funded organizations have driven positive social change and furthered justice and equality. NIF has provided over $350 million to more than 950 organizations since our inception in 1979.

Naomi Chazan Global Activism Fellowship

Want to travel to Israel/Palestine while advancing equality, democracy, and peace for all?

The New Israel Fund’s Naomi Chazan Global Activism Fellowship offers a one-of-a-kind opportunity to visit Israel/Palestine, meet frontline Israeli and Palestinian activists, and learn about issues of war, peace, and inequality by seeing the reality on the ground. 

Fellows will visit Israel/Palestine on November 3-10, 2026.

This trip is a great opportunity to learn alongside peers and friends (ages 21 – 35). NIF is based on the simple idea that those of us who share a commitment to Israel/Palestine and to progressive values can join together to work for equality, freedom, and human rights. You will join a cohort of participants from the U.S. and Canada building relationships across borders to be sustained for years to come.

Following the trip, participants are expected to organize at least two NIF events in their home communities, with support from NIF staff. These events could look like a report-back highlighting the participants’ learnings from the trip, educational programs featuring NIF grantees/partners, or something else entirely that is tailored to the intellectual, emotional, and spiritual needs of the fellow’s communities.

The program is subsidized by generous donors in the NIF community. All “on-the-ground” costs—your hotel accommodation and almost all meals—will be covered by NIF. Participants are responsible for purchasing their own airfare and travel/health insurance. If the cost of airfare is a barrier for you, please apply anyway. Limited airfare subsidies may be available.

About Us

The Arthur L. Carter Journalism Institute at NYU

We want to educate those who agree. Opportunities abound in the media world, but at NYU Journalism, the opportunity to do compelling work that informs, engages, and matters to the societies in which we live drives our faculty, motivates our students, and shapes our approach.

Those who find this their calling will discover encouragement, support, and an endless amount to learn at NYU. Our graduates are able to work anywhere their talents take them, and they do. Students come here not only to gain competence in the journalist’s craft but also the tools to make it better than it is. And those two things are the essence of what we teach.

Matthew Power Literary Reporting Award

Matthew Power was an award-winning journalist who reported empathetically on the human condition. He died in March 2014, while on assignment in Uganda.

About the Award

The Matthew Power Literary Reporting Award is a grant of $15,000 to support the work of a promising early-career nonfiction journalist on a story that uncovers truths about the human condition.

Offered for the first time in 2015, the Award has been endowed by individuals and organizations touched by the life and work of Matthew Power, a wide-roving and award-winning journalist who sought to live and share the experience of the individuals and places on which he was reporting. Power, a longtime friend of the Arthur L. Carter Journalism Institute, died in March 2014, while on assignment in Uganda.

The award proceeds from the recognition that many important stories need to be reported from afar, and that publications do not always have the resources to send a journalist where the story is. The money need not be used exclusively for travel, but we expect that most successful applications will include such expenses. A panel of NYU journalism professors, outside writers, and editors will review the proposals. Finalists will be asked to take part in an interview online.

The judges will be interested in perpetuating Power’s legacy, as his former editor Roger Hodge put it, of “strong, character-driven narratives with detailed scenes and lyrical description.” Power was always open to the absurdity that often attends politics and international affairs; he was always searching, as he put it, for “the human truth beneath the sorry facts.” Power’s ultimate ambition, he added, was literary beauty.

That said, judges will be looking for a journalist as singular in his or her own approach as Power was in his. In addition to longform print projects, we will consider audio projects involving substantial reporting and running over 20 minutes in length. The award will not fund proposals to report on armed conflicts where journalists are already imperiled, nor projects that are mainly investigatory. The winner will normally receive visiting scholar privileges at NYU, including library access.

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

Hendrix-Murphy Foundation

Enhancing literature & language at Hendrix College since 1978.

In homage to Bertie Wilson Murphy’s passion for the study and appreciation of literature and language, the Hendrix-Murphy Foundation at Hendrix College was founded in 1978 with an endowment by her son, Charles H. Murphy, Jr., former CEO of Murphy Oil Corporation. Mrs. Murphy was a 1905 graduate of Galloway Women’s College in Searcy, Ark., which merged with Hendrix College in Conway in the 1930s. Charles H. Murphy, Jr., was a member of the Hendrix Board of Trustees and served as chair. 

The Foundation's programs are overseen by a Board of Directors that is headed by the president of the College and includes Murphy family members, the provost, and representatives from the Hendrix Board of Trustees.

The Hendrix-Murphy Book Award

Hendrix is proud to offer the Hendrix-Murphy Book Award to an outstanding high school junior who demonstrates distinguished scholarship or leadership in literary studies (English, creative writing, foreign languages, or drama).

Hendrix-Murphy Book Award recipients will receive a copy of Poems to Read: A New Favorite Poems Anthology, edited by Robert Pinsky and Maggie Dietz.

Students may be nominated by their English, languages, creative writing, or drama teacher or guidance counselor by using the required form.

The Educational Theatre Foundation (EdTA) offers the Thespian Growth & Excellence Grants to support production expenses for school theatre programs. Grants of up to $1,000 can cover essential costs such as licensing fees, rentals, sets, and costumes. With a commitment to enhancing educational theatre, EdTA prioritizes applications based on demonstrated need, particularly for Title 1 schools, helping to foster creativity and collaboration in diverse educational settings.

The EdTA Thespian Growth & Excellence Grants support theatre programs by providing financial assistance for troupe expenses, including travel to professional productions and participation in state conferences. Founded by the Educational Theatre Foundation, these grants aim to enhance educational theatre access and representation. By the end of 2024, 349 grants totaling over $286,000 will have been awarded, benefiting schools with Title 1 designations and empowering students and educators in their creative pursuits.

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

• Subsidizing new, emerging, and underserved student theatre programs;
• Creating paths for theatre educators to develop new skills; and
• Commissioning research to showcase the value of a theatre education.

Educator & Program Grants

Giving school theatre programs a boost

The Thespian Growth & Excellence Fund is committed to supporting the ongoing development of theatre programs and the pursuit of excellence for educators, students, schools, and communities by offering a number of grants that assist in EdTA membership, teacher support, and programmatic resources for theatre in schools.

By the end of 2024, the Thespian Growth and Excellence Fund has awarded 349 grants to 276 schools, totaling $286,167 in assistance provided to school theatre programs, many at schools with Title 1 designations.

Equipment Upgrade (up to $5,000)

Can be awarded to help school theatre programs with large technical purchases that upgrade the resources available for theatrical use, such as lighting and sound equipment.

Tides Foundation

Tides is a partner for justice in the social sector, working closely with doers and donors to build the power of historically excluded groups who face systemic barriers. We provide fiscal sponsorship, donor advised funds, impact investing, and a variety of grantmaking solutions to advance social justice and equity. 

Through Tides Foundation, we partner with individuals and families, foundations, corporations, and social change leaders to design and deliver social impact initiatives that shift decision-making power back to the communities we serve. Our mission is our North Star — and a beacon for those who share our commitment to social justice. Together, we work to shift resources and power to communities historically denied both, so they can create a just and equitable future.

Neighborhood Power Grant 

The VYV Neighborhood Power grant entails a swift and concentrated allocation of resources to a designated geographic area to attain immediate, quantifiable outcomes within that specific area before or immediately following a pivotal date.  

The grant is designed to be a short cycle, rapid response investments in esteemed neighborhood-based organizations and leaders who mobilize civic participation within a defined local footprint. These grants support small teams collaborating closely with the community to enhance turnout and engagement around pivotal civic events.  

The tiered structure ensures a “right need, right time” approach by matching funding to an organization’s specific capacity and geographic footprint. 

Tier 1: Surgical Focus

• The Target: Small, grassroots organizations or neighborhood civic associations. 
• The Logic: This is laser-focused on SPLC-priority precincts. These are majority-minority areas where voters of color have lower-than-average turnout and face structural barriers. 
• The Footprint: Designed for a highly localized reach of approximately 2,000 to 5,000 voters. 

Tides Foundation

Tides is a partner for justice in the social sector, working closely with doers and donors to build the power of historically excluded groups who face systemic barriers. We provide fiscal sponsorship, donor advised funds, impact investing, and a variety of grantmaking solutions to advance social justice and equity. 

Through Tides Foundation, we partner with individuals and families, foundations, corporations, and social change leaders to design and deliver social impact initiatives that shift decision-making power back to the communities we serve. Our mission is our North Star — and a beacon for those who share our commitment to social justice. Together, we work to shift resources and power to communities historically denied both, so they can create a just and equitable future.

Neighborhood Power Grant 

The VYV Neighborhood Power grant entails a swift and concentrated allocation of resources to a designated geographic area to attain immediate, quantifiable outcomes within that specific area before or immediately following a pivotal date.  

The grant is designed to be a short cycle, rapid response investments in esteemed neighborhood-based organizations and leaders who mobilize civic participation within a defined local footprint. These grants support small teams collaborating closely with the community to enhance turnout and engagement around pivotal civic events.  

The tiered structure ensures a “right need, right time” approach by matching funding to an organization’s specific capacity and geographic footprint. 

Tier 2: Emergent Opportunity Areas A

• The Target: Small-to-medium-sized organizations.
• The Logic: Supports groups ready to scale beyond a single neighborhood into “place-based clusters,” such as specific cultural corridors. 

Tides Foundation

Tides is a partner for justice in the social sector, working closely with doers and donors to build the power of historically excluded groups who face systemic barriers. We provide fiscal sponsorship, donor advised funds, impact investing, and a variety of grantmaking solutions to advance social justice and equity. 

Through Tides Foundation, we partner with individuals and families, foundations, corporations, and social change leaders to design and deliver social impact initiatives that shift decision-making power back to the communities we serve. Our mission is our North Star — and a beacon for those who share our commitment to social justice. Together, we work to shift resources and power to communities historically denied both, so they can create a just and equitable future.

Neighborhood Power Grant 

The VYV Neighborhood Power grant entails a swift and concentrated allocation of resources to a designated geographic area to attain immediate, quantifiable outcomes within that specific area before or immediately following a pivotal date.  

The grant is designed to be a short cycle, rapid response investments in esteemed neighborhood-based organizations and leaders who mobilize civic participation within a defined local footprint. These grants support small teams collaborating closely with the community to enhance turnout and engagement around pivotal civic events.  

The tiered structure ensures a “right need, right time” approach by matching funding to an organization’s specific capacity and geographic footprint. 

Tier 3: Emergent Opportunity Areas B

• The Target: Medium-to-large-sized organizations. 
• The Logic: Targeted at groups rooted in entire regions or multiple neighborhoods with consistent engagement history and multiple paid staff.

About QuikTripQuikTrip believes in investing in the communities in which our employees live and work. Every year, QuikTrip donates 5% of our annual net profit to qualified 501c3 non-profit agencies, which includes our United Way campaign match, support for National Safe Place agencies, Folds of Honor scholarships and many other agencies that support at-risk youth and early childhood education.Mission: To wisely invest dollars in community efforts that will help impact (in measurable terms) individuals in our society who are dependent on the charitable support of others. We believe the most effective way to do that is to invest our contribution dollars and volunteers in strategic efforts that help those at risk reach their functional capacity as successful, independent citizens.About QuikTrip Charitable GrantsQuikTrip funds 501c3 agencies located in the cities in which we have stores and our employees live and work. Funding can include: “in-kind” products (coupons, gift cards or product donation), formal grants, fundraiser/event sponsorships and employee volunteer time.Focus Areas:

• Creating Safe Communities
  • First Responders: QuikTrip is proud to partner with law enforcement and first responders in every market we serve, making sure that they have the tools, training and support they need to keep our communities safe and to return home safely to their families after each shift.
  • Homeless Outreach & Alternatives to Police Response: To significantly reduce non-emergency calls and help people in crisis get back on their feet, QuikTrip funds dedicated homeless outreach teams across our communities. These teams engage individuals experiencing homelessness and living in encampments – connecting people to services, shelter, detox and long-term care.

• Creating Strong Communities
  • Ending Homelessness: We support emergency, transitional and permanent supportive housing, diversion and prevention programs, and more.
  • Mental Health & Substance Abuse : We know that healthy communities are safe communities, which is why we invest in detox and substance abuse treatment centers, and behavioral health centers and services to end the perpetuation of cycles of trauma and addiction.
  • At-Risk Youth: We especially prioritize services for at-risk youth – those aging out of foster care, justice-involved or without stable support systems.
• Additional Community Commitments
  • United Way: Employee donation matching in all markets.
  • Folds of Honor: Scholarships for families of fallen or wounded service members and first responders.
  • National Safe Place: QT stores serve as Safe Place locations for youth in crisis, with trained staff ready to assist.

Dick & Judy Hoyt Inclusion Grant

The Doug Flutie, Jr. Foundation for Autism is excited to collaborate with the Hoyt Foundation for the Dick and Judy Hoyt Grant for Inclusion. Our joint effort is driven by a shared vision of fostering a society where individuals with autism and other disabilities are embraced and valued within their communities. In tribute to the pioneering spirit of Dick and Judy Hoyt, we will be distributing $50,000 through this community grant to support people with autism and other disabilities. Successful ways grant funds can be used: 

• Side-by-side participation with non-disabled peers in a swim program, the grant provides a private lifeguard to allow individualized support to ensure an inclusive experience.
• Grant provides the purchase of a racing chair to allow an individual with a disability to run in races with non-disabled peers.
• Competitive horseback riding supported by the grant to purchase specialized equipment to allow a rider to compete against non-disabled peers.
• Grant provides the purchase of an adaptive ski prosthetic to allow an individual to participate side by side with non-disabled peers on their high school ski teams.
• Participation in dance training and competitions to allow a student with a disability to compete in a dance competition with non-disabled peers, grant lessons, and staff to assist in dance training.
• Grant provides a mobile stand to allow a student with a disability to participate side by side with non-disabled peers in the college marching band. 

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Resident Research Award

Provides residents and fellows an opportunity to attend and present their scientific research at the SIR Annual Scientific Meeting. The intent is to expose young researchers who wish to further their careers in interventional radiology.

Award

Up to two recipients will receive complimentary registration and a travel stipend of $1,000.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Research Scientist Award

Recognizes the contributions and accomplishments of PhD scientists and engineers at all levels of training for their basic and preclinical research on the topic of interventional radiology.

Award

Up to two recipients will receive complimentary registration and a travel stipend of $1,000.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Dr. Gary J. Becker Young Investigator Award

Promotes excellence in academic research for members early in their careers. This award honors the founding editor of the Journal of Vascular and Interventional Radiology (JVIR) and recognizes the importance of the young investigator in developing interventional solutions for the future.

About

In 1990, SIR Foundation established the Dr. Gary J. Becker Young Investigator Award as a way to recognize promising young practitioners of interventional radiology early in their careers and encourage their pursuit of academic careers. Each year, the author of the most outstanding clinical science research paper submitted receives this distinguished award.

Award

$3,000 honorarium along with complimentary registration to the SIR Annual Scientific Meeting.

The award will be presented during the SIR Foundation Awards Ceremony at the SIR Annual Scientific Meeting.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Dr. Constantin Cope Medical Student Research Award

Introduces interested medical students to the greater interventional radiology community at the SIR Annual Scientific Meeting. Recognizes the student author of an accepted abstract that best honors the spirit of inventiveness and scientific purity.

Award

Up to two recipients will receive complimentary registration and a travel award of up to $1,000.

Dr. Barry T. Katzen Master Clinician Award

Honors an interventional radiologist who exemplifies dedication to clinical practice, patient care, diligence in their work and continuous improvement within the field and who has also made a demonstrable impact at their institution or practice as a result.

About

The Dr. Barry T. Katzen Master Clinician Award seeks to honor an interventional radiologist who exemplifies dedication to clinical practice, patient care, diligence in their work and continuous improvement within the field as well as who has made a demonstrable impact at their institution or practice as a result. This award recognizes individuals who have made significant contributions to enhancing patient outcomes and advancing the reputation and practice of interventional radiology through their hard work, commitment and, most importantly, clinical practice. The award is being given in the name of Barry T. Katzen, MD, FSIR, who pioneered clinical practice for IR in 1976 and became a vocal advocate, champion and example for colleagues of the importance of IR being a clinical discipline for advancement of the specialty.

The recipient will receive:

• Complimentary annual meeting registration
• Recognition during the SIR Annual Scientific Meeting

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Excellence in Innovation Award

Fund compelling, novel ideas that lead to improved health outcomes in IR.

About

Interventional radiologists create and introduce novel, minimally invasive procedures and devices that help solve some of our toughest medical challenges. To continue this rich history of innovation in IR, the purpose of this award is to fund compelling, novel ideas that lead to improved health outcomes in IR.

Innovation, for this purpose, is broadly defined as any use of emerging methods, new devices, new procedures or new technologies, such as artificial intelligence and nanotechnology, that display an exceptional degree of potential for transforming and advancing the specialty of interventional radiology.

The Annual Meeting Research Award Committee selects one recipient for this award each year.

The recipient will receive:

• Complimentary annual meeting registration
• Travel stipend up to $1,000
• The opportunity to present their research as well as meet peers, network with senior scientists and participate in learning opportunities at the SIR Annual Scientific Meeting
• Recognition during the SIR Annual Scientific Meeting

About the ASHFoundation

ASHFoundation supports innovators and sparks innovation in communication sciences. We give early support to promising students, researchers, and clinicians exploring bold ideas to transform the field and improve people's lives.

Artificial Intelligence in Communication Sciences and Disorders Research Grant

About

The American Speech-Language-Hearing Foundation (ASHFoundation) invites investigators to submit proposals for up to four research grants ranging from $25,000 to $50,000. The Artificial Intelligence in Communication Sciences and Disorders Research Grant (AI in CSD Research Grant) supports interdisciplinary studies that advance the ethical, clinically and scientifically grounded application and integration of artificial intelligence (AI) into communication sciences and disorders (CSD) practice and service delivery. Funding may be applied to one- or two-year studies.

Specific Objectives of the Funding Opportunity

As part of this initiative, the ASHFoundation invites proposals that implement AI technologies to transform clinical practice, education, and research in CSD. Proposals that are submitted under this funding opportunity must meet the following:

• Include interdisciplinary research teams that integrate clinicians and AI researchers,
• Address clinically relevant questions or have a clear translational potential, and
• Cover one or more of the following priority areas: AI-driven assessment and diagnosis; personalized and adaptive interventions; equitable access to care; data infrastructure for predictive analytics; technology innovation; prevention for public health; and ethical standards for AI integration.

Grant Guidelines

To advance its mission to build a responsible and equitable technology ecosystem, the Kapor Foundation makes strategic grants across three focus areas: (1) Computing Education, (2) Innovation, and (3) Governance.

Within each focus area, we fund research on critical topics at the intersection of racial equity and tech, capacity-building that strengthens coalitions and movement-building infrastructure, and policy advocacy that drives systemic change.

Funding Priorities

We fund organizations and initiatives aligned with our core focus areas:

Given advances in Al, a new vision of education is urgently needed — one that ensures students are equipped with the technical skills to build emerging technologies and the critical skills to navigate their socio-technical implications. We fund computing education initiatives across K-12, postsecondary, and alternative pathways that expand computing participation at scale, shift policy to ensure equitable access, and expand the pipeline of educators prepared to teach computing.

2. 

Al is being designed, developed, and deployed rapidly, yet the communities most affected by its impacts are largely excluded from its creation and subsequent economic benefits. We support organizations and individuals that build responsible Al technologies, leverage technology to close gaps in access and opportunity, and invest in initiatives and coalitions that advance responsible Al in the entrepreneurship and venture capital ecosystems.

3.

As Al adoption accelerates, bolder approaches to regulation are necessary to protect marginalized communities from technological harm, expand economic opportunity, and ensure the benefits of technology reach everyone. We support efforts that build awareness of key policy issues, develop policy agendas, and mobilize coalitions.

For 2026, our priority advocacy areas are: 1) computing education, 2) algorithmic bias, 3) Al safeguards for children, 4) data center development, and 5) surveillance and civil rights.

The MPPEP Phase 3 program aims to enhance processing capabilities for invasive, wild-caught catfish, benefiting both processors and fishers. By increasing processing capacity and volume, the initiative seeks to create fair wages and stable job opportunities, fostering economic growth in rural areas. This grant will support innovative strategies that ensure sustainable practices and elevate incomes within the community, thus contributing to the overall development of the meat and poultry sector.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Interventional Research Studies of Brentuximab Vedotin-Based Novel Combinations in AITL and PTCL-NOS

This competitive program is designed to support interventional InvestigatorSponsored Research aimed at generatin clinical evidence for brentuximab vedotin in novel combination approaches in angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma–not otherwise specified (PTCL-NOS).

Project Types and Area of Interest

Studies considered for Pfizer support should address key clinical and scientific gaps in the use of brentuximab vedotin in AITL and PTCL-NOS irrrespective of CD30 expression, with a focus on evaluating the safety and efficacy of novel brentuximab vedotin–based combinations with therapies available for PTCL treatment that are supported by a clear scientific rationale grounded in mechanism of action and/or disease biology.

Mary Kay Ash Foundation

Guided by Mary Kay Ash’s dream to enrich the lives of women everywhere, the Mary Kay Ash Foundation® raises and distributes funds to invest in breakthrough cancer research and clinical trials to find a cure for women-related cancers and ending domestic violence.

Since 1996, the Mary Kay Ash Foundation®, a 501(c)3 organization, has contributed more than $100 million to organizations aligned with its two-fold mission. In addition, the Foundation supports awareness initiatives, community outreach programs, and advocates for legislation to ensure women are healthy and safe. Through our global charitable foundations in Brazil, Canada, China and the United States, we are collectively making a deeper impact on the lives of women around the world.

Mary Kay Ash Foundation: Cancer Research Grant

The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.

Grant proposals are reviewed by a Scientific Research Review Committee comprised of notable members of the American medical and scientific community. Grants are awarded up to $100,000 (combined direct and indirect costs) for a two-year period. The Foundation anticipates funding between 10 and 15 grants annually. 

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For technically ambitious or higher-risk, earlier-stage concepts focused on feasibility testing, assay or workflow prototyping, and initial cost-reduction validation. Intended approaches that require focused development to demonstrate viability.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For concepts with preliminary feasibility evidence that are ready to advance from prototype toward an integrated workflow—optimizing performance, broadening assay or pathogen coverage, and generating more robust cost-reduction and performance data.