Best Franklin County Grants for Nonprofits in Maine

The Smart Family Fund is a private foundation dedicated to supporting early-stage non-profits that demonstrate the potential for scalable, positive impact. With grants ranging from $25,000 to $100,000, they aim to assist organizations in refining their models and preparing for larger investments. The foundation, guided by three brothers, focuses on mentoring and backing social entrepreneurs facing challenges in securing funding for innovative yet untested ideas, fostering a brighter future for communities.

The Rona Jaffe Foundation Fellowship supports emerging women writers with a fully funded 7-month residency at the Fine Arts Work Center. Established by the Rona Jaffe Foundation, it includes a $2,500 prize to assist with travel and living expenses. Eligible candidates must be U.S. residents, at least 18 years old, and not enrolled in a degree program during the fellowship year. This prestigious fellowship aims to nurture exceptional literary talent.

This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

This Funding Opportunity Announcement (FOA) aims to advance the identification and evaluation of candidate biomarkers for neurological and neuromuscular disorders. By facilitating the clinical development of neurotherapeutics, the FOA encourages research that includes both animal studies and preliminary human evaluations. The ultimate goal is to produce biomarkers ready for rigorous analytical and clinical validation, enhancing the effectiveness of treatments in clinical practice.

The Limited Competition: Basic Instrumentation Grant (BIG) Program, supported by the NIH, invites applications from institutions that have not received significant S10 funding in recent years. This program provides a minimum award of $25,000 and allows for a maximum of $350,000 to purchase specialized instruments essential for NIH-supported research. Eligible instruments include cell sorters, confocal microscopes, and more, promoting advancements in biomedical research.

The Shared Instrumentation Grant (SIG) Program supports NIH investigators in acquiring high-cost, specialized instruments essential for research. With a minimum award of $50,000 and a maximum of $750,000, this program facilitates the purchase or upgrade of equipment like mass spectrometers and light microscopes. It encourages collaborative efforts among researchers to enhance capabilities and foster innovation in biomedical research.

The High-End Instrumentation (HEI) Grant Program, funded by the NIH, supports NIH-supported investigators in acquiring high-end, specialized instruments. With a minimum award of $750,001 and a maximum of $2,000,000, this program aims to enhance research capabilities. Eligible instruments include nuclear magnetic resonance spectrometers, mass spectrometers, and advanced imaging systems, among others. Applications are due by 5:00 pm local time of the applicant organization.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.

The Reboot Representation Tech Coalition aims to significantly increase the number of Black, Latina, and Native American women earning computing bachelor’s degrees. They invite qualified organizations to submit grant inquiries focused on recruiting and retaining these women in tech. Programs that leverage existing resources and operate across multiple regions will be prioritized, and the Coalition seeks initiatives backed by substantial research and community trust.

The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.

This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.

This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.

The Extramural Discovery Science Accelerator Award supports the commercialization of ongoing cancer research projects, focusing on experiments that facilitate technology validation and de-risking. Applications are accepted on a rolling basis, with a budget of up to $75,000 for one year. This award encourages independent investigators at any career stage to advance their technologies, with a strong emphasis on commercial viability and collaboration within a learning community.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

The Green Chemistry Student Chapter Award recognizes ACS student chapters for their commitment to green chemistry initiatives. This award highlights the importance of green chemistry in education, encouraging students to engage in activities that promote sustainability. Eligible chapters must submit detailed summaries of at least three green chemistry projects, demonstrating their understanding of the principles and practices that contribute to a more sustainable future.

The Special Wildlife Funds - Duck Stamp Grants program in Canada focuses on the development of waterfowl propagation areas specifically for the Mississippi Flyway. It supports projects in Manitoba and Saskatchewan aimed at enhancing breeding populations of migratory waterfowl. This initiative is funded through the sale of State Migratory Waterfowl Stamps and is targeted at not-for-profit organizations dedicated to the conservation and promotion of wild waterfowl, ensuring sustainable habitats and effective management practices.

The NIDA Research Education Program (R25) supports educational activities that enhance training in biomedical, behavioral, and clinical research. Aimed at clinicians and clinical researchers, this program focuses on increasing knowledge about substance use and related disorders. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline. This initiative is crucial for developing a skilled workforce to address the nation's research needs.

The Advancing Research Careers (ARC) Predoctoral to Postdoctoral Transition Award (F99/K00) aims to support late-stage graduate students from diverse backgrounds in transitioning to postdoctoral research positions. It fosters impactful careers in the biomedical research workforce by facilitating doctoral completion and mentoring opportunities. The program emphasizes networking, professional development, and participation in organized cohorts, aligning with NIH's mission to promote diversity in research careers.

The Limited Competition Small Grant Program for ORIP SERCA K01 Recipients provides funding to early-stage veterinary scientists to enhance their research capabilities and transition to independent investigator status. This initiative addresses challenges faced by these researchers, including reliance on funding from senior investigators. Grants support pilot studies, secondary data analysis, and development of research methodologies, aiming to foster independence within a two-year timeframe without funding clinical trials.

The NIDCR Small Grant Program for New Investigators (R03) supports early-stage scientists in dental and craniofacial research. It funds pilot studies and developmental projects aimed at generating preliminary data for future Research Project Grant (R01) applications. Key deadlines for applications include February 16, June 16, and October 16 from 2025 to 2027, addressing the need for timely submissions in this competitive funding landscape.

The Aging Research Dissertation Awards aim to enhance the diversity of the scientific workforce engaged in aging research. These awards support dissertation projects aligned with the National Institute on Aging's strategic priorities. Applicants are encouraged to submit Letters of Intent prior to the deadlines, which occur quarterly from February 2025 to October 2026. This funding opportunity seeks to cultivate innovative research addressing aging and aging-related health issues.

The Live Más Scholarship, offered by the Taco Bell Foundation, supports students aged 16-26 pursuing higher education and workforce readiness. Emphasizing passion and impact, applicants showcase how their interests drive positive change in their communities. The foundation is dedicated to breaking down educational barriers, fostering creativity across various fields including arts, technology, and entrepreneurship. This initiative empowers young dreamers to turn their aspirations into actionable goals, creating meaningful contributions to society.

The Simons Dissertation Fellowship in Mathematics, offered by the Simons Foundation, supports exceptional Ph.D. students in their final years of study. This fellowship, honoring co-founder Jim Simons, provides $19,200 annually for research support and departmental funds, commencing September 1, 2025. Eligible candidates must be full-time Ph.D. students in a U.S. mathematics department, entering their third year. The program emphasizes research quality, significance, and potential impact.

The Betsy & Ryan Colwell Mentorship Scholarships for Women in Thoracic Surgery support early-career female cardiothoracic surgeons by facilitating mentor relationships and networking opportunities at the WTS Annual Conference. Each scholarship, valued at $2,500, covers conference registration, lodging, and travel expenses. Two scholarships will be awarded annually starting in 2025, aiming to empower women in a specialty where they are underrepresented and help them navigate their challenging career path.