Upcoming Webinar
Instrumentl Fall Launch: Grant Work, Leveled Up.
Thu, Oct 29 or Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Franklin County Grants for Nonprofits in Mississippi

Looking for grants for 501(c)(3) nonprofit organizations working in Franklin County, Mississippi? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.56B

Total funding

$5K

Median grant

9,000+ grants
$2.56B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,112 Results based on applied filters

Tides Stronger Together Fund Grant

Tides Foundation
Private
United States
Unspecified amount
The Tides Stronger Together Fund, under the Tides Foundation, provides essential support grants to fiscally sponsored partners focused on historically underserved communities. By building organizational capacity and leadership, the fund empowers community changemakers to address inequities and enhance sustainability. With a pooled funding model, it directly responds to the needs of over 120 partners, ensuring resources are effectively allocated where they are most impactful, ultimately fostering long-term community resilience.
Community Services

Goldman Fund: Democracy & Civil Liberties

Lisa & Douglas Goldman Fund
Private
United States
Unspecified amount
The Lisa and Douglas Goldman Fund, established in 1992, supports charitable organizations that enhance society, focusing on democracy and civil liberties. The fund prioritizes projects that ensure equal citizen participation in the democratic process and protect civil liberties, especially those implemented nationally or across multiple states. It operates by invitation only and emphasizes flexible, informed grantmaking to qualified projects that align with its mission and values.
Governance & Democracy Civic Engagement & Education Gun Violence Prevention +1 more

HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed) (357655)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.
Chronic / Acute Pain Anesthesia and Pain Medicine Drug Use Disorder +1 more

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) (357658)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Limited Competition Small Grant Program under the NCATS CTSA aims to enhance the research capabilities of scholars transitioning to independent academic translational scientists. This program supports diverse clinical and translational science projects, including pilot studies and methodology development. The R03 grants are designed for short-term projects with limited resources that generate preliminary data for future R01 applications, thereby fostering innovation and advancing health research.
Science Biology Health & Medicine +2 more

Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) (357667)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,250,000
The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.
Health & Medicine Pharmacology Biomedical informatics +4 more

Outdoor Recreation Legacy Partnership Program (ORLP) Recurring Notice 5 Year

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $15,000,000
The Outdoor Recreation Legacy Partnership Program (ORLP) is a competitive grant initiative by the National Park Service, aimed at enhancing parks and recreational opportunities in urban, underserved communities. This program supports the acquisition, development, and renovation of outdoor recreation areas through federal funding, addressing the needs of community organizations, local governments, and recognized tribes. Applications are accepted twice a year, before June 1 and November 1.
Parks & Public Spaces Outdoor Recreation Outdoor Equity

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 1

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 2

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding - Cycle 3

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.
Health & Medicine Medical Ethics Artificial Intelligence (AI)

Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Risk and Protective Factors of Family Health initiative invites research proposals to explore family health and resilience, addressing health disparities in minority communities. Key submission deadlines are set for various dates from February 2025 to February 2027. This program is supported by the National Institutes of Health, highlighting the importance of family well-being as a critical area for advancing health equity. Proposals should focus on interventions that improve family health outcomes.
Family Services Minority Services Health Disparities & Social Determinants of Health

ASTS: Veloxis Fellowship in Transplantation Grant

American Society Of Transplant Surgeons
Private
North America
US $85,000
The ASTS: Veloxis Fellowship in Transplantation Grant offers $42,500 per year for two years to support clinical training in solid organ transplantation. This grant is aimed at current transplant surgery trainees who have completed their surgical residency and are committed to the field. Awardees must attend the ASTS Award Ceremony and complete their fellowship at the same institution for the duration of the award, ensuring a focused and comprehensive training experience.
Surgery Organ And Tissue Banks

Dogs for Joy Grant

Joy In Childhood Foundation Inc
Private
Alabama, Arizona +42 more
US $80,000 - US $150,000
The Dogs for Joy Grant, funded by the Joy in Childhood Foundation, supports the integration of trained facility dogs in pediatric hospitals. These dogs provide emotional support, help children cope with medical procedures, and enhance overall well-being. The program aims to increase the presence of in-residence dogs, as research highlights their positive impact on reducing anxiety and improving patient outcomes. Grants typically cover multi-year funding, promoting innovative animal-assisted therapy approaches in healthcare settings.
Service Animals Children’s Health & Pediatrics

Dunkin' Joyful Spaces Grant

Joy In Childhood Foundation Inc
Private
Alabama, Arizona +42 more
US $75,000 - US $150,000
The Dunkin' Joyful Spaces Grant supports children's hospitals and community health centers in creating joyful environments for pediatric patients. Launched in 2022, this initiative helps fund play areas, healing gardens, and other kid-friendly spaces, enhancing the hospital experience. Grants typically range from $25,000 to $65,000 annually, with a maximum of $150,000 over three years. This opportunity encourages creativity in designing spaces that provide comfort and joy to children and their families during hospital stays.
Children’s Health & Pediatrics

Dunkin’ Prom Grant

Joy In Childhood Foundation Inc
Private
Alabama, Arizona +42 more
US $20,000 - US $50,000
The Dunkin’ Prom Grant, provided by the Joy in Childhood Foundation, aims to bring joy to teenage patients unable to attend their own prom due to illness. By funding hospitals to host prom-like events, the program ensures these patients experience this significant milestone. Grants typically range from $20,000 to $50,000, supporting the creation of memorable events with themes, food, entertainment, and formal wear for the teens, making a positive impact in their lives.
Youth Services Patient Care & Services Children’s Health & Pediatrics

Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed) (357250)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.
Drug Use Disorder Addiction & Substance Use Disorders Drug Safety

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) (357256)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.
Stroke

NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NCI Pathway to Independence Award (K99/R00) supports talented postdoctoral researchers in transitioning to independent faculty positions. This program provides essential NCI research funding to facilitate the development of competitive, independent research careers. Applications are due by 5:00 PM local time of the applicant's organization, emphasizing the importance of timely submissions for prospective awardees.
Biology Health & Medicine Medical Education & Professional Training

Applied regulatory science research to evaluate and treat cardiotoxicity of oncology therapeutics

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.
Cancer / Oncology Drug Safety

Research Opportunities for New and At-Risk Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity invites R01 applications aimed at fostering diversity in the research workforce by supporting New and At-Risk Investigators from underrepresented backgrounds in health-related sciences. The program is aligned with the mission of the participating NIH Institutes and Centers and seeks to promote independent, innovative research projects. Applications are due on specific dates throughout 2025-2027, with a focus on enhancing diversity in scientific research.
Science Health & Medicine Diversity, Equity & Inclusion +1 more

Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required) (357282)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,125,000
The Academic Research Enhancement Award (AREA) supports small-scale research at institutions that receive limited NIH funding, emphasizing biomedical research for undergraduate students. This program aims to enhance the research environment and provide valuable experiences for students. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over four of the last seven years. This funding opportunity encourages investigator-initiated minimal risk clinical trials to advance NIH missions.
Biology Health & Medicine Medical Education & Professional Training

Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required) (357288)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.
Preventative Healthcare Health Disparities & Social Determinants of Health Addiction & Substance Use Disorders +3 more

NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required) (357301)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Multi-Site Feasibility Clinical Trials (R01) invites applications for clinical trials focused on mind and body interventions. This program emphasizes the need for multisite feasibility studies to gather essential data for future efficacy trials. The initiative is designed to enhance public health by addressing gaps in scientific knowledge related to the delivery, recruitment, and data collection of integrative health approaches. Deadlines for submissions range from February 2025 to October 2026.
Integrative & Alternative Health

Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required) (357303)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites applications for investigator-initiated clinical trials that deliver complementary and integrative health interventions remotely or via mobile health technologies. Emphasizing no in-person contact, the trials should demonstrate feasibility, safety, and potential clinical benefits. A Plan for Enhancing Diverse Perspectives is required for submission, and applicants are encouraged to consult with NCCIH contacts before applying. Deadlines for submissions range from February 2025 to October 2026.
Integrative & Alternative Health Telemedicine & Telehealth

NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program (R25 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program aims to enhance the training of a diverse workforce in biomedical research. This initiative encourages recent college graduates from various backgrounds to gain hands-on research experience, particularly in vision science. The program supports educational activities focused on research experiences, ensuring participants are from a nationally recruited cohort. This funding opportunity is crucial for advancing the mission of the NEI and fostering inclusivity in scientific research.
Eye Diseases & Disorders Vision Impairment Care & Services

Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required) (357305)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The Feasibility Clinical Trials of Mind and Body Interventions grant aims to support trials that examine complementary and integrative health approaches for high-priority NCCIH research topics. This opportunity seeks to gather essential data for designing future efficacy studies, focusing on aspects such as feasibility, acceptability, and recruitment strategies. The goal is to bridge gaps in scientific knowledge and enhance public health impact through rigorous clinical research. Applicants are encouraged to contact NCCIH representatives for guidance.
Integrative & Alternative Health

Women Chemists Committee + Lilly Emerging Talent Award

American Chemical Society
Association/Society
United States
Unspecified amount
The Women Chemists Committee + Eli Lilly Travel Award supports female chemists at undergraduate, graduate, and postdoctoral levels, enabling them to attend meetings and present their research. This initiative aims to enhance women's participation in the chemical sciences. Awards are based on scientific merit and financial need, covering registration, travel, and accommodations for U.S.-based meetings. Recipients also benefit from networking opportunities, including poster sessions and luncheons, fostering connections with ACS governance and peers.
Chemistry

The Hearst Journalism Awards Program - Writing - Feature Writing

William Randolph Hearst Foundation
Private
United States
Unspecified amount
The Hearst Journalism Awards Program, established in 1960, supports undergraduate journalism education through a range of competitions and substantial awards totaling up to $700,000. Open to students enrolled in ACEJMC-accredited institutions, the program encourages excellence in writing, photojournalism, audio, television, and multimedia. With opportunities for individual and group submissions, it aims to foster talent and enrich the field of journalism, while the Hearst Foundation continues its legacy of educational philanthropy.
Writing & Literature

Franklin County Grants for Nonprofits Highlights

Looking for Franklin County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Franklin County grants recommended for your specific programs in Mississippi.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Mississippi

Average Grant Size

What's the typical amount funded for Mississippi?

Grants are most commonly $94,687.

$94,687

Total Number of Grants

What's the total number of grants in Franklin County Grants for Nonprofits year over year?

In 2024, funders in Mississippi awarded a total of 8,599 grants.

2022 7,983

2023 8,165

2024 8,599

Top Grant Focus Areas

Among all the Franklin County Grants for Nonprofits given out in Mississippi, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Franklin County Grants for Nonprofits changing over time?

Funding has increased by 2.35%.

2022 $634,985,073

2023 $789,259,908
24.30%

2024 $807,768,252
2.35%

Mississippi Counties That Receive the Most Funding

How does grant funding vary by county?

Oktibbeha County, Hinds County, and Lafayette County receive the most funding.

County Total Grant Funding in 2024
Oktibbeha County $274,520,115
Hinds County $230,593,243
Lafayette County $93,085,023
Harrison County $41,719,363
Madison County $39,767,542