Best Grants for 501(c)(3) in Iowa

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) grant invites applications for mid-phase clinical trials focusing on natural products such as botanicals and dietary supplements. It aims to advance scientific knowledge by determining optimal dosing and patient responses. Applicants must provide preliminary data demonstrating bioavailability and measurable impacts on target engagement. This initiative will not support efficacy trials for cancer treatments and encourages early contact with NCCIH scientific contacts.

The Lucille M. Tiro Scholarship, offered by the Delaware Community Foundation, provides a one-time award of $1,000 to a graduating female senior from the Indian River School District. Applicants must demonstrate high academic achievement and financial need, with preference given to those pursuing degrees in the Arts. This scholarship is part of a broader initiative by DCF, which awarded a record $850,000 to 245 students for the 2024-2025 school year, fostering educational opportunities in Delaware.

The Cloutier-Valenti Legacy Scholarship, funded by the Delaware Community Foundation, offers a one-time award of $1,000 to graduating seniors from selected high schools in Delaware. Eligible students must enroll in an accredited institution, demonstrate financial need, and show involvement in community activities. The scholarship aims to support students pursuing degrees in science, contributing to the foundation's mission of enhancing educational opportunities and equity in the community.

Ezekiel Hennessey Mitchel Scholarship Fund

The Ezekiel Hennessey Mitchel Memorial Scholarship is designated for graduating high school seniors from Benton, Polk, Lincoln, and Linn Counties pursuing careers in vocations such as the following:

• Home building trades
• Tile setting
• Carpentry
• General contracting
• Electrical
• Plumbing
• HVAC
• Welding
• Entrepreneurship and/or small business development
• Other trades defined by Benton Community Foundation

Students must attain certificates or degrees from accredited trade schools, technical schools, or community colleges. 

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.

The Eleanor B. and Henry H. Stroud, M.D. Memorial Scholarship, offered by the Delaware Community Foundation, provides a one-time award of $5,000 to Delaware residents pursuing medical degrees. This scholarship emphasizes excellence, ethics, and compassion in medicine, along with financial need and academic promise. Eligible applicants can reapply for up to four annual awards, with special consideration for those demonstrating innovation in medicine. The DCF awarded a record $850,000 in scholarships to 245 students for the 2024-2025 academic year.

The NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) aims to support innovative research in behavioral and social interventions for dental, oral, and craniofacial conditions. This funding opportunity includes a milestone-driven planning phase of up to 2 years, with potential transition to implementation for an additional 5 years, facilitating comprehensive trial development and assessment.

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

MidAmerica National Bank’s Employees Children Scholarship Fund

The MidAmerica National Bank’s Employees Children Scholarship Fund was established in 2005 by MidAmerica National Bank to provide scholarship support to the children of bank employees. It is open to students graduating from high school or currently enrolled in an undergraduate college or vocational program.

Delaware Art & Design Scholarship

Awards:

• One time award of $20,000. Students may reapply each year.

The Alaska Community Foundation

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives.

Scholarships at ACF

Each year, more than 60 scholarships are available to Alaska students—and it all starts with one simple application. With one login and one application, you’ll be considered for every scholarship you may be eligible for. Whether you’re taking your first step toward college, training for a career, or continuing your education, these scholarships are here to help carry you forward, backed by donors who believe in Alaska’s students and the futures they’re building. 

Gary Martin Swim Scholarship Fund

This is a scholarship established in memory of Gary Eugene Martin, and is open to Alaska students entering or enrolled in colleges or trade schools who have been involved in competitive swimming at the high school level in Alaska. 

The Gary Martin Swim Scholarship Fund was established with The Alaska Community Foundation in 2015. Gary Eugene Martin was a longtime resident of Soldotna, Alaska who lifted others up with his positivity and encouraging nature. His list of volunteer activities is long and reflects how much he cared about those he shared a community with. Gary was known to his family as someone who loved animals and spoiled his grandchildren. He showed his passion for helping youth through his involvement in competitive swimming. For years, he served as an official coach and mentor to many young swimmers.

His legacy carries on today through the awarding of the Gary Martin Swim Scholarship. 

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Vietnam Veteran’s Moving Wall Fund

The Vietnam Veteran’s Moving Wall Fund Scholarship was established to support the children of local veterans who served in the Vietnam War or subsequent conflicts. It was created in 1990 by the Vietnam Veteran’s Moving Wall Committee using remaining funds originally raised to bring the National Vietnam Veteran’s Moving Wall Exhibit to Glen Oak Park in Peoria, Illinois. The exhibit honors the 58,126 Americans who lost their lives during the Vietnam War.

Dennis Jones and Wayne Johnston Memorial Dice Run Scholarship

This fund provides a scholarship for a graduating senior from either Olean High School or Allegany-Limestone Central School who will be attending a 4-year college, with preference for a student planning to study business or business related field (i.e. accounting, finance, marketing, economics etc.)

The Incubator Grant, offered by the Society of Interventional Radiology Foundation, supports projects that enhance interventional radiology through clinical research. Eligible applicants must be SIR members and hold relevant degrees. The grant provides funding up to $25,000 for one year, specifically for developing clinical study protocols and proposals. This initiative emphasizes inclusivity and encourages innovative approaches in patient care, aligning with the foundation's mission to advance the specialty and improve patient outcomes.

The Pilot Research Grant, offered by the Society of Interventional Radiology Foundation, supports innovative research in interventional radiology to improve patient care. Grants of up to $35,000 are available for full-time faculty and post-doctorates with relevant degrees in the U.S. and Canada. Applicants must be current SIR members and can submit proposals for preliminary data generation, enhancing their chances for future funding opportunities.

The Radiology Resident Research Grant, funded by The Society of Interventional Radiology Foundation, aims to promote research among residents in accredited clinical radiology training programs in the U.S. and Canada. With a budget of up to $20,000 for 12 months, this grant encourages innovative research projects that advance interventional radiology and improve patient care. Eligible applicants must designate a project advisor and secure a three-month commitment from their residency program, fostering a supportive research environment.

Romero Family Scholarship Fund

Fund was established to provide scholarship assistance to further the education of able and deserving young men and women in their post high school education in the fields of either technical, vocational, academic or professional education, with preference given to students from Henry and Franklin Counties and the City of Martinsville.

Amount

• $2,500+

The Annual Community Grant by the Greater Jefferson County Foundation supports educational, cultural, and civic initiatives in Jefferson County, Iowa. With over $1.79 million awarded, grants assist local non-profits with capital improvements and operational costs. Eligible organizations must be 501(c)3 or government units, focusing on projects that benefit children, families, and community development. However, funding excludes past projects, individuals, and religious purposes. This initiative fosters community betterment and engagement across various sectors.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Project Types and Area of Interest

Potential applicants are encouraged to identify and address preclinical/basic science data generation for TFPI modulation/rebalancing in their local setting. This may include:

• Rare bleeding disorders which arise from deficiencies in different clotting factors or pathway components but converge on a common functional endpoint which is an impaired thrombin generation (e.g., Factor II, Factor V, Factor VII, Factor X and Factor XI deficiencies, as well as von Willebrand disease).
• Other diseases such as Glanzmann's thrombasthenia (GT) that have a distinct pathophysiological mechanism.
• Other rare bleeding disorders whose mechanisms are not well understood (e.g., Bleeding Disorder of Unknown Cause, BDUC).

Early Career Talent Development General Application

The UNCF Student Professional Development Programs (SPDP) Department works closely with some of the nation’s leading corporations and foundations to shape and execute internship programs, including both stand-alone internship programs and internship-and-scholarship programs

The UNCF Student Professional Development Programs (SPDP) Department works closely with some of the nation’s leading corporations and foundations to shape and execute internship programs, including both stand-alone internship programs and internship-and-scholarship programs with two goals – 

• To help companies build a more diverse workforce; 
• To provide diverse students with the preparation they need to succeed in college, familiarize themselves with professional career paths, and prepare to be competitive candidates for internships and future employers after graduation.

UNCF’s SPDP partners include The Walt Disney Company, Toyota, Papa Johns, United Health Foundation, Wells Fargo, and the Walton Family Foundation. We currently serve over 1500 students annually through internship, leadership, and professional development services.

The UNCF Student Professional Development Programs (SPDP) offer career readiness, success coaching, and paid summer and semester internships to college students. Students participating in SPDP will be exposed to career pathways and opportunities and have access to leadership and personal development training. 

SPDP students will:

• Prepare to navigate from college to early-stage careers
• Enhance professional experiences through meaningful internships
• Develop stronger project management skills
• Improve networking and communication skills
• Strengthen interviewing techniques 

Currently, the SPDP is sourcing candidates to fill for summer 2026 internships!! The Early Career Talent Development General Application is used to establish an applicant pool of potentially eligible students for these ongoing internship/student professional development opportunities that are published/unpublished. Internship or professional development opportunities using the Early Career Talent Development General Application, are restricted to students who are enrolled full time at an accredited institution within the U.S. during the 2025-2026 academic year. 

The Willis C. Helm Charitable Trust, established in 1954, focuses on supporting organizations that work on juvenile delinquency and the development of boys from broken homes. It provides annual grants averaging between $5,000 and $15,000, with a total giving of around $60,000 for five grants each year. Eligible organizations must be 501(c)(3) exempt and preferably located in Minnesota. Applications are accepted year-round, with a deadline of March 31 for annual review.

Agog Open Call: Climate Futures + Immersive Media

This open call supports immersive media projects that help people better understand and respond to climate challenges and imagine what a better world could be.

We are looking for projects that use immersive technologies—including smart glasses, augmented reality, spatial sound, and mixed reality—to create more engaging, experiential forms of climate storytelling and civic participation.

The open call will support projects across a range of stages and formats, from early ideas to more developed work. What matters most is a compelling story or experience, a clear sense of purpose, and a thoughtful approach to bringing the work to life.

Grants may be awarded in denominations ranging from $25,000 to $200,000. In addition to funding, selected projects may receive mentorship, advisor support, and opportunities for partnership and distribution.

The Bayer Fund Health & Wellness Grant Program aims to support organizations that provide education and resources for patients and caregivers facing cancer and cardiovascular diseases. Grants focus on assisting communities, particularly the African American population, in managing these health issues. Funding covers educational services, disease awareness, and access to care, with all activities to commence post-funding decisions. Eligible organizations must hold a 501(c)(3) status and operate within 55 miles of Bayer sites.

The Braly Trade / Vocational Scholarship, offered by the Longmont Community Foundation, supports individuals over 21 pursuing a trade or vocational education. This one-time award of $5,000 is allocated for tuition, fees, books, and other educational expenses. The scholarship honors the Braly family’s legacy in trades and aims to empower recipients to positively impact their communities. Applicants must be high school graduates or hold a GED and plan to attend an accredited institution in the U.S.

Marshall High School Scholarship

The Alison Shuemake Scholarship is for a Marshall High School senior and graduates pursing an academic or technical degree or certification.

Applications are open year-round. After we receive all application requirements, we internally review applications and make decisions within two weeks of receipt. An email will be sent to the applicant to complete follow up requirements.

Scholarship payments are sent directly to the school.

The A Woman’s Work Founders Scholarship, provided by the Longmont Community Foundation, supports women in the Longmont and St. Vrain Valley area who demonstrate financial need and a commitment to their education. With awards ranging from $500 to $5,000, this scholarship prioritizes applicants who have shown resilience in overcoming challenges. By empowering women, the scholarship aims to foster individual achievement and strengthen the community, creating pathways to sustainable futures.

The National Institute of Neurological Disorders and Stroke (NINDS) aims to support innovative research for validating therapeutic targets in Alzheimer's Disease-Related Dementias (ADRD). This initiative focuses on overcoming barriers in treatment development by ensuring well-validated targets linked to disease mechanisms. By employing a phased award mechanism, NINDS seeks to enhance the rigor of target validation, facilitating the transition from basic discoveries to clinical applications, ultimately accelerating the development of effective therapeutic strategies.

The Sioux City Public Schools Music Participation Grant, managed by the Siouxland Community Foundation, aims to support low-income students in Sioux City, Iowa, by providing access to instrumental and choral music programs. This grant is designed to cover individual lessons, participation fees, and instrument repairs, ensuring that financial barriers do not hinder students' engagement in music education. Preference is given to initiatives that directly benefit students, fostering their musical development and opportunities.