Best Grants for 501(c)(3) in Iowa

The American Electric Power Foundation provides grants to 501(c)(3) organizations focused on educational improvement, particularly in STEM fields, and basic human services such as hunger and housing. Organizations must operate within AEP's service territory or have a broader beneficial purpose. The Foundation also supports social justice initiatives and environmental protection efforts. Eligible applicants must affirm compliance with anti-discrimination policies and demonstrate commitment to diversity and inclusion.

The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.

The JFNY Grant for Arts & Cultural Exchange supports U.S. non-profit organizations aiming to enhance understanding of Japanese arts and culture. Eligible projects include performances, workshops, and exhibitions, with priority given to those with additional funding and in areas with limited access to cultural events. Applications must be submitted at least one month prior for online projects and three months for others. The grant covers expenses like travel, publicity, and artist fees, and is reimbursed upon project completion.

The Roy J. Carver Charitable Trust provides grants primarily to 501(c)(3) tax-exempt organizations in Iowa and parts of Illinois. Focused on enhancing educational opportunities, the Trust supports projects in elementary and secondary education, higher education, medical research, youth services, and recreation. By funding innovative initiatives, it aims to improve access to educational resources and foster scientific advancement, while also addressing the recreational needs of youth and supporting community development.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

Community Foundation of the Quincy Area

My Community Foundation (also known as The Community Foundation Serving West Central Illinois & Northeast Missouri) is a tax-exempt 501(c)(3) nonprofit organization dedicated to improving quality of life in the communities it serves by connecting compassionate donors with meaningful causes. The foundation works with individuals, families, businesses, and nonprofit partners to gather charitable contributions, grow those funds through professional investment strategies, and grant the earnings in ways that address local needs now and into the future. It builds and manages permanent endowments tailored to donors’ goals, ensuring their philanthropic visions—whether honoring a loved one, establishing a legacy, or supporting community needs—are realized. Serving a 12-county region across West Central Illinois and Northeast Missouri, the foundation acts as a steward of charitable assets, helping donors make a lasting impact through customized giving opportunities, community grants, and strategic support for nonprofit organizations.

Delford M. & Portia K. Richter Agriculture Scholarship

Delford M. & Portia K. Richter Agriculture Scholarship provides financial support to students pursuing education in agriculture-related fields. Selection is based on academic achievement and promise, demonstrated financial need, the likelihood that the recipient will return to Pike County or Calhoun County to engage in farming, the applicant’s ability to successfully complete their chosen program, and how well the educational program aligns with the applicant’s ongoing course of study. Awards are made annually in the spring.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

Overview and General Information

In 1988, the Iowa Legislature established Iowa Code 256A creating the Child Development Coordinating Council (CDCC) and funding the Shared Visions Preschool Programs. The mission of the CDCC is to advocate for Iowa’s children and families and support comprehensive programs for children meeting risk factors and their families. The CDCC advises the Iowa Department of Education (Department) regarding the administration and implementation of state funded at-risk programs for children ages birth to five. The Department administers the Shared Visions Preschool Program which provides comprehensive quality preschool program experiences for children meeting identified risk factors who are ages three to five years. 

The Department is issuing a competitive application to fund Shared Visions Preschool Programs. The purpose is to solicit applications that will enable the CDCC to select grantees who will provide a Shared Visions Preschool Program created in accordance with Iowa Code section 256A, Iowa Code section 279.51, and the rules in 281—Iowa Administrative Code 64.

Shared Visions Programs

Iowa’s Shared Visions Programs are state-funded early childhood initiatives that support the healthy development and early learning success of young children across the state. Through high-quality preschool and parent support services, these programs help build strong foundations for learning, strengthen families and ensure every child has the opportunity to reach their full potential.

Together, these programs represent a vital investment in the future of Iowa’s youngest learners.

The Communities of Care Technical Assistance Provider Grant aims to enhance rural Iowa service providers' capabilities by offering expert guidance, assessments, and technical assistance. This initiative, supported by the Iowa Department of Health and Human Services, focuses on evidence-based methods to improve care delivery. Key activities include co-location, cost-sharing agreements, and optimizing patient flows within the Communities of Care Projects, contributing to the broader Iowa Healthy Hometowns Project.

Purpose:

The purpose of this competitive grant is to strengthen internal coherence and sustainability between IDEA-DA and ISPP supports in order to enhance district leadership capacity, infrastructure, coaching systems, and school improvement efforts. Through this alignment, the grant aims to accelerate progress in narrowing the achievement gap for students with disabilities by ensuring that evidence-based practices are implemented with fidelity, resources are strategically leveraged and supports are embedded into long-term district systems. This initiative seeks to build sustainable structures that improve outcomes, increase equity across buildings and districts and ensure that students with disabilities receive high-quality instruction and inclusive opportunities across all educational settings.

Parent Support Grant

The Shared Visions Parent Support Program grants provide funds for educational support services to parents of children ages birth to five and who are determined to meet certain at-risk criteria as defined in 281—Iowa Administrative Code 64. Priority for funding will be given to applicants who serve parents of children ages birth to three years and meeting at-risk criteria. Iowa Code 279.51 governs these grants. 

Overview and General Information

In 1988, the Iowa Legislature established Iowa Code 256A creating the Child Development Coordinating Council (CDCC) and funding the Shared Visions Parent Support Program. The mission of the CDCC is to advocate for Iowa’s children and families and support comprehensive programs for families with children meeting risk factors. The CDCC advises the Iowa Department of Education (Department) regarding the administration and implementation of state funded at-risk programs for families with children ages birth to five. The Department administers the Shared Visions Parent Support Program which provides comprehensive educational support services for families with children meeting identified risk factors who are ages birth to five years. 

The Department is issuing a competitive application to fund Shared Visions Parent Support Programs. The purpose is to solicit applications that will enable the CDCC to select grantees who will provide a Shared Visions Parent Support Program created in accordance with Iowa Code section 279.51 and the rules in 281—Iowa Administrative Code 64. 

Iowa Early Head Start State Grant 

Purpose

Renewal of existing Iowa Early Head Start (EHS) State funding opportunity.

Grant Purpose:

The purpose of the Iowa EHS State Grant is to increase the capacity of providers of Infant/Toddler services to successfully maintain adherence to requirements of the Head Start Program Performance Standards (HSPPS) through collaborative partnerships within Early Head Start programs. The focus of this grant serves to increase collaboration through birth-five partnerships as an infrastructure underpinning to leverage federal funding opportunities specific to EHS grants.

Impact: 

• Increase and influence success of partnership and collaboration between Child Care and Head Start; 
• Expand the number of children, families, staff, administration and systems Iowa EHS State allocation funds influence; 
• Increase efforts in focus areas of coaching and mentoring to increase staff education, instructional practices, family support, business practices and infrastructure through systems work and collaboration with EHS. 

The Minnesota Twins Community Fund, established in 1991, has significantly impacted youth sports in Twins Territory by providing over $24 million in support. Through grants and donations, they empower young athletes, emphasizing the importance of teamwork and personal growth. The fund focuses on 501c3 nonprofits in their region, ensuring that initiatives foster both athletic skills and character development. With strict guidelines for donations, the Twins continue to enhance community engagement and inspire the next generation of leaders.

The Great American Cleanup Grants, offered by Keep America Beautiful, aim to enhance community beautification and environmental efforts across the U.S. This initiative encourages KAB affiliates to remove litter, plant greenery, and restore public spaces, contributing to the larger goal of cleaning up 25 billion pieces of litter by 2026. With cash grants available, this program fosters collaboration among communities, promoting sustainable practices and a cleaner, greener future for all.

The Norfolk Southern Trades on Track SkillPointe Scholarship offers $5,000 scholarships for students pursuing trades education related to the rail industry. Eligible candidates must be enrolled in a post-secondary institution and focused on railway-related trades. With over 1,000 scholarships funded and a mission to close the skills gap, this initiative empowers individuals towards high-demand careers without requiring a four-year degree, ultimately strengthening the workforce and economy.

Service Objects In-Kind Grants support non-profit organizations dedicated to environmental conservation and sustainability. By leveraging their data validation services, they aim to assist projects that promote ecological health and responsible resource management. The program prioritizes applications with clear, measurable objectives and impactful outcomes within one to three years. Organizations with 501(c)(3) status in the U.S. are eligible, while initiatives lacking detailed plans or focusing on generalized education will not qualify. This grant fosters community involvement in environmental stewardship.

FY27 RFP FWBPEFS27001 for Iowa Fatherhood Initiative

Description

The purpose of this Request for Proposal (RFP) # FWBPEFS27001 is to solicit applications that will enable the Iowa Department of Health and Human Services (referred to as Agency) to select the most qualified applicant to provide comprehensive fatherhood services, including family economic advancement, parenting education, access and visitation supports, financial literacy, and employment readiness programming to strengthen families and promote self-sufficiency. 

The US Department of Health & Human Services, through the NIH, invites applications for innovative approaches to implement SBIRT/P for addressing alcohol, tobacco, and other drug use in adults facing health disparities. This funding opportunity encourages research that tests screening, brief interventions, and referrals for treatment or prevention services. Applications are due on specified deadlines from February 2024 through March 2027, fostering collaboration with healthcare and community partners to enhance public health outcomes.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.

The Great Apes and Gibbons Program Grant, administered by the Arcus Foundation, supports conservation efforts for great apes and gibbons across 24 priority landscapes in Africa and Asia. The program emphasizes sustainable coexistence between humans and wildlife, having awarded over 2,000 grants to more than 500 organizations globally. Funding is not available for individuals or specific lobbying activities, ensuring resources are directed towards impactful conservation initiatives.

The Express Health Information Outreach Awards aim to enhance public health by increasing access to biomedical information for U.S. health professionals and the general public. These awards support projects that improve health information literacy among consumers and caregivers, ensuring they can effectively find and utilize health information. Focused on partnerships and outreach to underrepresented communities, the initiative seeks to promote healthy behaviors, prevent illness, and improve health outcomes through informed decision-making.

The Ethnic Minorities and Women’s Internship Grant supports entry-level athletics administrative positions for one academic year, promoting diversity in NCAA Division II. It provides $30,000 for intern salaries and $3,000 for professional development, benefiting six schools annually from a total budget of $180,000. Eligible applicants must be active NCAA members, with a focus on enhancing ethnic minority and gender representation in athletics administration. This initiative encourages professional growth and compliance in diverse environments.

The Iowa Barn Foundation's Matching Grant - IBF Restoration Grant aims to preserve Iowa's iconic barns, which are vital to the state's heritage. With over $1 million awarded in matching grants, the foundation supports barn owners in restoring structures that are at least 50 years old or hold historical significance. Projects that enhance the rural landscape receive priority, ensuring these agricultural symbols are maintained for future generations.

The Iowa Department of Natural Resources (DNR) offers the Snowmobile Trail Grant Program, providing financial support for the development and maintenance of snowmobile trails using registration fees. Managed by the Iowa State Snowmobile Association, the program ensures public access to trails and supports equipment purchases for trail grooming, fostering outdoor recreation and conservation efforts in Iowa.

The Prairie Meadows Legacy Grant Program offers substantial funding ranging from $100,000 to $1 million for impactful projects in central Iowa. This initiative supports various categories including arts, economic development, education, and health services. By funding iconic projects like the Principal Riverwalk and Pappajohn Sculpture Garden, the program plays a vital role in revitalizing the Greater Des Moines area, enhancing community resources and fostering cultural growth.

The Marvin R. and Pearl E. Patterson Family Fund Scholarship, offered by the Grand Haven Area Community Foundation, supports students aspiring to study graphic or fine arts, as well as those interested in environmental sciences. Open to high school graduates from the Tri-Cities area, this scholarship considers leadership, community involvement, and academic achievements, although financial need is not a requirement. Applicants must provide transcripts and relevant documents to qualify for this opportunity.