Best Grants for New Nonprofits in Iowa

The ASTRO-AstraZeneca SCLC Therapy Challenge RFP aims to enhance research on limited-stage small cell lung cancer (LS-SCLC) through innovative combination therapies, particularly integrating immunotherapy with advanced radiation techniques. Proposals are encouraged to explore various aspects, including care patterns, treatment workflows, prognostic biomarkers, and toxicity management. The target budget for projects ranges from $175,000 to $375,000, with consideration given to higher requests based on scientific merit, fostering significant advancements in radiation oncology.

The Marlene and Spencer Hays Foundation Grants support tax-exempt organizations working to enhance lives through arts, healthcare, education, and youth programs. The foundation requires a Letter of Intent (LOI) from all applicants, emphasizing its mission to select grant recipients who align with its values. Grants are not available for political purposes, endowment campaigns, or organizations that discriminate based on race, gender, or religion. This framework ensures a focused impact on community betterment.

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

The BioMarin Grant aims to support events, activities, and projects that enhance public health and benefit patients with rare diseases. This corporate funder focuses on scientific innovation and provides resources for organizations such as hospitals, universities, and patient advocacy groups. With an emphasis on education and community support, BioMarin encourages applications for funding throughout the year, ensuring timely assistance for eligible projects.

The IEN-WMAN Mini-Grant Program provides crucial financial support to Indigenous communities and grassroots organizations impacted by mining in the U.S. and Canada. With over $200,000 distributed annually in $4,000 grants, the program aims to address mining-related environmental and health issues. Priority is given to proposals that demonstrate a direct impact on affected communities, particularly Indigenous-led initiatives, ensuring that financial assistance is directed where it is most needed.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

Dr. Marlene Caroselli Excellence-in-Communication Scholarship

Purpose of Scholarship

To recognize those high school seniors who have consistently demonstrated excellence in both the spoken and written word and plan to pursue college and a career that requires excellence in communication.

Number and Size of Awards

Number of recipients and award amounts vary; award amount may be split between two or more recipients. Award paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters. Average award $5,000; not to exceed the cost of tuition.

Donor Information

A former St. John Fisher College professor who understood and greatly admired the hard work and challenges of single-parent students created this scholarship to support their higher education endeavors and to improve their employability, their lives, and the lives of their children.

The Sloan Indigenous Graduate Partnership (SIGP) Scholarship Program, funded by the A.P. Sloan Foundation, aims to support Indigenous graduate students in STEM fields. This program, a collaboration among the Montana University System institutions, offers scholarships, professional development, and networking opportunities to enhance the academic journey of Indigenous students. With awards of $20,000 for M.S. and $40,000 for Ph.D. candidates, the SIGP seeks to increase the number of Indigenous scholars earning advanced degrees in science and engineering.

The Chairman Tommy Taylor Memorial Scholarship

The Chairman Tommy Taylor Memorial Scholarship was opened by the Texas Alliance of Energy Producers in 2014 in memory of Tom Taylor, a former chairman of the alliance. He was a prominent figure in the oil & gas industry and an esteemed leader. The one-time $2,500 scholarship is for graduating seniors and currently enrolled college students who have graduated from a Texas high school. The student's field of study must be energy or oil and gas industry-related, including petroleum, geology, and engineering. The award can be used at any college or university.

About Alex’s Lemonade Stand Foundation

Alex's Lemonade Stand Foundation (ALSF) emerged from the front yard lemonade stand of 4- year-old Alexandra “Alex” Scott, who was fighting cancer and wanted to raise money to find cures for all children with cancer. Her spirit and determination inspired others to support her cause, and when she passed away at the age of 8, she had raised $1 million. Since then, the Foundation bearing her name has evolved into a national fundraising movement. Today, ALSF is one of the leading funders of pediatric cancer research in the U.S. and Canada, funding research projects and providing programs to families affected by childhood cancer. ALSF is one of the only childhood cancer research organizations that has been given the NCI peer-reviewed funder designation for rigorous selection of research grants. The mission of ALSF is to change the lives of children with cancer through funding impactful research, raising awareness, supporting families, and empowering everyone to help cure childhood cancer.

Bio-Therapeutic Impact Award

The Bio-Therapeutic Impact Award accelerates the development of clinical trials for promising biologic approaches to treating childhood cancer. These approaches include, but are not limited to, immunotherapy, gene therapy and small molecules. The award, intended for investigators who are initiating clinical trials, totals the maximum of $1.8 million awarded over three years.

The Cystic Fibrosis Foundation's Screening Improvement Program (SIP) Award aims to enhance early diagnosis of cystic fibrosis (CF) through improved newborn screening processes. This initiative emphasizes equitable screening practices for diverse populations and seeks innovative approaches to strengthen communication with primary care providers. Grants of up to $75,000 per year for two years are available to support projects that focus on algorithm transformation and best practices in screening, without funding clinical trials.

The AACR-Torrey Coast Foundation Transpacific Gastric and Esophageal Cancer Research Partnership Grant supports innovative research on upper gastrointestinal malignancies, which are responsible for over one million deaths globally in 2023. This grant encourages collaboration between U.S. and Asian institutions, focusing on resistance, metastasis, and novel treatment strategies. Proposals should detail plans for clinical translation and are open to researchers at all career stages, especially those new to upper GI cancer research.

The Bernice M. Brightbill Fund Scholarship offers a one-time award to a senior female student from the Central Dauphin School District pursuing a college degree in business studies. This scholarship aims to support students demonstrating financial need, regardless of citizenship or documentation status. Eligible applicants can apply for multiple scholarships and may be selected for any or all they qualify for, promoting accessibility in education.

The NIA Expanding Research in AD/ADRD Postbaccalaureate Research Education Program aims to enhance the research workforce by providing intensive research experiences for recent graduates. This initiative supports early-stage investigators in Alzheimer's Disease and related dementias, addressing a critical shortage of researchers in the field. Participants engage in independent research, mentorship, and professional development, equipping them with skills necessary for advanced degrees and research careers in aging and dementia. The program fosters innovation and interdisciplinary collaboration essential for advancing AD/ADRD research.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

John W. Burandt Scholarship

Purpose of Scholarship

To provide support for tuition, fees, books, and other expenses associated with post-secondary education for dependents of firefighters residing in the city of Rochester, NY.

Number and Size of Awards

One award of $2,000; paid in the Fall and and divided equally between the Fall and Spring semesters.

Donor Information

This scholarship was established by Mrs. Lorene (Rene) Burandt in honor of her husband, John W. Burandt, a dedicated firefighter who served the Rochester community for 30 years.

The Clinical Research Training Scholarship in Parkinson's Disease, funded by the Parkinson's Foundation and the American Brain Foundation, supports young investigators in clinical studies related to Parkinson's disease. Offering $65,000 annually for two years, plus an additional $10,000 for education and research costs, this award aims to foster rigorous clinical research. Eligible applicants must have an MD, PhD, or equivalent degree and be AAN members, focusing on patient-oriented research with human subjects.

The Pediatric Oncology Student Training (POST) Program Grant, offered by Alex’s Lemonade Stand Foundation, aims to foster the next generation of pediatric oncology researchers. This summer internship provides undergraduate, graduate, and medical students with hands-on research experience in a supportive environment, focusing on diversity and inclusion. Grants will specifically support students from underrepresented communities in the scientific workforce, enabling impactful research and mentorship opportunities to advance pediatric cancer care.

The Eash-Potter Scholarship supports LGBTQ youth in central Pennsylvania, honoring Melinda Eash and Sharon Potter's legacy. It is available to graduating high school seniors from specific counties who demonstrate commitment to enhancing the community climate for LGBTQ+ individuals. Financial need is a consideration, and the scholarship is a one-time award. Students of color, transgender individuals, and children of LGBTQ+ parents are particularly encouraged to apply, promoting diversity and inclusion within the scholarship program.

The Douglas W. Pfautz Memorial Scholarship Fund honors a dedicated community servant and family man, Doug Pfautz. Sponsored by the Rotary Club of Elizabethtown, this scholarship supports high school seniors from the Elizabethtown Area School District who demonstrate good moral character and a commitment to community service. Applicants must maintain good academic standing and plan to pursue further education. This one-time award encourages students to embody the Rotary motto of 'Service Above Self', continuing Doug's legacy of service.

The James B and Lois R Archer Charitable Foundation offers Large Grants for requests exceeding $10,000. Focused on fostering positive change, the foundation supports initiatives in Arts and Culture, Civic Engagement, Education, Health, and Human Services. Eligibility includes 501(c)(3) organizations, while restrictions apply to consecutive grant cycles and non-qualifying purposes such as endowments and fundraising events. Organizations are encouraged to apply for various projects to enhance community well-being.

The James B and Lois R Archer Charitable Foundation offers Smaller Grants of $10,000 or less to support initiatives in Arts and Culture, Civic Engagement, Education, Health, and Human Services. Organizations must have 501(c)(3) status and comply with eligibility criteria, including a one-year waiting period for reapplications. The foundation aims to have a significant impact on communities, especially in West Texas, while avoiding funding for specific exclusions such as endowments and fundraising events.

The Lynn E. Poffenberger Memorial Scholarship Fund, established by the Middle Paxton Lions Club, honors the legacy of Mr. Poffenberger by providing annual scholarships to two graduating seniors. Eligible applicants must reside in Middle Paxton Township or Dauphin Borough, demonstrate financial need, and show active community involvement. This one-time scholarship aims to support deserving students in their educational pursuits, reflecting the values of service and commitment to the community.

The Alzheimer’s Association and ASNR Imaging Research Grant focuses on advancing imaging research in Alzheimer’s and other neurodegenerative diseases. This partnership aims to support early-stage pilot projects that develop novel imaging tools and innovative data analysis methods. Up to three proposals will be funded, with each award capped at $200,000 for one year, promoting significant advancements in the field and enhancing research capabilities for better understanding of dementia.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Jerry J. Murphy MSW Scholarship Fund

The Jerry J. Murphy MSW Scholarship Fund provides scholarships to students pursuing a Master of Social Work degree.

Jerry Murphy is the retired Executive Director of the INC Board. He served residents of Kane County for over 28 years during his time with the organization.

INC Board, NFP, is an Illinois, not-for-profit corporation which was chartered as Mental Health and Mental Retardation Services on April 21, 1969, to promote the creation of local mental health boards authorized under 405 Illinois Compiled Statutes §20/3a.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Olsson Roofing Company, Inc. Scholarship Fund

In 1988, Olsson Roofing Company, Inc. of Aurora created a scholarship fund within the Community Foundation for area students.

Scholarships from this fund are awarded in recognition of high scholastic achievement, participation in school activities and leadership potential.

These awards are reserved for students whose parents are actively involved in the roofing trade or construction industry.

Through the generosity and commitment of this civic-minded company, many students have received needed assistance for their college educations.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Robert L. & Marjory J. Nelson Memorial Scholarship Endowment Fund

This fund provides scholarships to students pursuing a career in the medical field of study with a preference to those students entering the field of nursing.

Marjory Nelson (1928-1998) received her bachelor of arts degree from Aurora University and her R.N. certification from the Copley Hospital School of Nursing.

She also undertook additional graduate studies at Northern Illinois University and the National College of Education.

She was employed by Copley Memorial Hospital and later served as a nurse for the East Aurora Schools.

This fund was created by Mrs. Nelson’s family and friends to provide recognition of her extraordinary dedication to the field of nursing.

Upon the passing of her husband Robert, the Nelson family added his name to the fund.

Robert Nelson (1924-2015) was a veteran of World War II. He served with the Navy in Europe and the Marines in the Pacific.

He worked in the field of education and was a retired principal in School District 44 in Lombard, Illinois.

Mr. and Mrs. Nelson were survived by two daughters and three grandchildren.

Created in 2004, the fund became an endowment in 2005.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Theodore Silseth Nelson Scholarship Endowment Fund

This fund provides scholarships to students returning to school after a lapse of several years since high school graduation. The awards are given to students pursuing a two or four-year degree in health care, with a preference for both financial need and students seeking a registered nurse certification. Theodore Nelson (1937-2017) was employed as a large commercial account underwriter in the insurance industry. He created this fund out of respect for the competency of those in the healthcare profession and to encourage those who wish to improve themselves by returning to school after being in the workforce. 

The Community Practice Innovation Award by the Rheumatology Research Foundation aims to foster innovative ideas from the rheumatology community that enhance practice implementation and sustainability. Grants, up to $80,000 for one year, support projects in quality improvement, implementation, and pilot studies. Recipients are expected to share findings with the broader community through presentations and disseminate tools developed with the funding. This initiative emphasizes improving patient care through effective collaboration and innovative practices.