Best Operating Grants for Nonprofits in Iowa

The Paul Calabresi Career Development Award for Clinical Oncology aims to enhance the training of clinician-scientists in clinical and translational cancer research. This funding opportunity encourages the career growth of researchers but does not permit Scholars to lead independent clinical trials. Instead, it allows participation in clinical trials under the mentorship of an experienced researcher, fostering a collaborative approach to cancer research.

Feld Entertainment's Charitable Contributions aim to support children in need through various initiatives. Their donations have significantly impacted organizations like St. Jude Children's Research Hospital and the Make-A-Wish Foundation. They offer cash and in-kind contributions to help underserved communities, providing tickets to nonprofit youth organizations and funding educational programs in the performing arts. Employees are encouraged to engage in local charity events, reinforcing the company's commitment to making a difference in the communities they serve.

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

William T. Maunsell Memorial Scholarship Fund

To support graduating seniors from Westfield High School, Westfield Vocational Technical High School and St. Mary’s High School in Westfield who have average grades and are pursuing degrees in education, criminal justice or nursing.

Additional Guidelines

• Students can receive up to $3,000 in scholarships from the Community Foundation.
• Scholarship awards could impact the financial aid offered by a college, and students are advised to check with their college financial aid offices about this.
• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. Some part and/or all the award could be considered taxable income. It is advisable students check with the college or tax accountant regarding this matter.

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Easterby Family Scholarship ($7,000)

This renewable scholarship is for students from Laurens County, South Carolina who are pursuing graduate or post-graduate education in the fields of theology or medicine. 

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Beth Bryan Creative Arts Fund Scholarship

Graduating senior from any high school in Cumberland County.

The Actions of Public Witness Grant, offered by the Unitarian Universalist Funding Program, provides matching grants of up to $1,500 to Unitarian Universalist congregations engaging in timely actions of public witness. This initiative supports efforts in social and environmental justice, encouraging congregations to mobilize during critical moments. Grants are available on a rolling basis and are intended for urgent projects that extend beyond the regular grant timeframe. Notably, individual applications are not accepted.

Who We Are

OneStar strengthens Texas communities by creating pathways for individuals and organizations to engage, connect, and accelerate their impact.

OneStar AmeriCorps VISTA Project

OneStar AmeriCorps VISTA Project places skilled individuals with a diverse range of backgrounds at nonprofits and agencies throughout the state of Texas. AmeriCorps VISTA members serve full-time for one year on capacity-building projects to advance your organization’s anti-poverty mission.

OneStar AmeriCorps VISTA Project places community-driven individuals with nonprofits & agencies throughout Texas on transformative projects focused specifically on building organizational capacity and infrastructure to alleviate poverty. Get the support you need to accelerate your efforts in volunteer management, marketing, community outreach, fundraising, program development, and more!

Capacity building activities include:

• Volunteer Engagement
• Fundraising & Development
• Communication & Marketing
• Community Engagement & Outreach
• Program Development

The Ed & Mildred Schroeder Scholarship, offered by the Coastal Bend Community Foundation, aims to enhance the quality of life in the Coastal Bend through educational support. This scholarship is available to graduating seniors or current college students pursuing a degree in education, demonstrating financial need, and enrolled in at least 12 credit hours. By providing effective grants and scholarships, the foundation fosters community philanthropy and addresses local educational needs.

The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.

The Artist in Business Leadership (ABL) Fellowship supports Native artists in building sustainable art-centered businesses. This yearlong program provides $10,000 in funding along with professional development and networking opportunities. Eligible applicants must be 18 years or older, reside in the U.S., and be enrolled in or have lineage from a federally recognized tribe. The fellowship aims to empower artists to thrive within their communities while honoring their cultural heritage.

The Kors, Lois E., Educational Scholarship, established by the Beatrice Educational Foundation, aims to support Beatrice High School graduates in pursuing higher education. With a strong commitment to academic achievement and civic involvement, the Foundation awards over $55,000 annually in scholarships. Applicants must demonstrate financial need, citizenship, and academic merit. This scholarship encourages students to enter the teaching profession, providing essential funds to help them achieve their educational goals.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

JustJane Art Scholarship Fund for Women

Truly unique humans like Jane Marie Ewing do not populate the universe very often, and the JustJane Art Scholarship for Women was created to honor her remarkable spirit.

Jane was an artist at heart, finding joy in countless creative pursuits – whether baking delectable treats, capturing life’s beauty through photography, or expressing her imagination in fashion and digital illustration. Her zest for life was infectious, often bringing laughter through her playful “Jane Pranks”, which will forever live in the hearts of family and friends. Jane shared an inseparable bond with Kyle, each the center of the other’s universe. Tragically, Jane was taken from this world unexpectedly in 2025.

Her vibrant artistic soul touched every aspect of her life – from painting and interior design to crafting costumes for parties and pranks. Though her passion for art wasn’t fully nurtured early on, once she embraced it later in life, creativity flowed freely, illuminating the lives of everyone around her. Jane saw beauty everywhere, and her art became a reflection of that vision.

This scholarship carries forward Jane’s legacy, helping future generations cultivate their own artistic passions. It is a reminder to future generations that art has the power to transform lives.

The OJJDP FY 2026 Internet Crimes Against Children On-Line Child Protection System (ICACCOPS) funding opportunity aims to enhance and maintain critical investigative tools for child exploitation cases. ICACCOPS provides a robust IT infrastructure to support data services, network security, and management tools for law enforcement. This initiative strengthens the efforts of the national network of ICAC Task Forces, which are dedicated to combating technology-facilitated child sexual exploitation across the United States.

Community and Economic Development Department 

The City of Davenport Community and Economic Development department focuses on fostering growth and improving the quality of life in Davenport, Iowa. It offers various programs and incentives aimed at supporting small businesses, commercial development, and housing initiatives.

This department also oversees urban planning and development services, ensuring compliance with local regulations and facilitating community engagement. Its initiatives, such as the DREAMFRESH Initiative, aim to enhance the overall economic landscape of the city.

HOME Investment Partnership

Each year the City receives two primary community development grants from the federal government: 

• Community Development Block Grant (CDBG), approximately $1 million per year
• HOME Investment Partnership, approximately $300,000 per year

These funds are for activities benefiting low and moderate income residents and are restricted to uses that meet federal regulations in the areas of affordable housing, community development, and economic development.

General information about eligibility and federal requirements can be found here: National Objectives, Subrecipients Handbook.

HOME funds are awarded to affordable housing activities on a project by project basis. Consideration by the City Council may be required based on the size and/or cost of the affordable housing development being proposed.

CED staff oversees the application, construction, and compliance process for HOME funds.

The Donaghue Foundation's Greater Value Portfolio Grant Program aims to enhance healthcare value by funding innovative research projects for two years, with awards up to $400,000. It encourages proposals that address issues such as high costs, disparities, and inefficiencies in care. Eligible applicants include Ph.D. researchers at nonprofit institutions partnered with healthcare organizations. The program seeks actionable solutions to improve patient care and reduce the burden of low-value healthcare on communities.

The Karim Thomas Ziyad Memorial Engineering Scholarship Fund supports students from Washington County or nearby areas pursuing a career in engineering, especially in Mechanical Engineering. Established in memory of Karim Thomas Ziyad, this scholarship aims to empower deserving students to achieve their educational goals. The fund is part of the Community Foundation of Washington County Maryland, which offers numerous scholarships to enhance educational opportunities for local students.

About RWJF

At the Robert Wood Johnson Foundation, we take bold leaps to transform health in our lifetime and pave the way, together, to a future where health is no longer a privilege, but a right. We take our responsibilities seriously, and pledge to work in ways that reflect our values.

Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions

RWJF seeks to fund one lead organization or consortium to serve as a national network-weaver for diversity, equity, inclusion, and belonging (DEIB) in the health professions. The selected grantee will connect and support leaders, organizations, and institutions across the ecosystem, strengthening relationships, aligning strategy and communications, and facilitating shared learning and collective action. By building the connections and infrastructure needed for collaboration, the grantee will help advance belonging, accountability, and systems change across health professions education and healthcare institutions.

Achieving a healthcare system grounded in equity requires both a diverse health professions workforce and institutions committed to advancing diversity, equity, inclusion, and belonging (DEIB). While diverse teams improve quality of care and health outcomes, RWJF has learned that increasing representation alone is insufficient without addressing structural and institutional barriers that shape belonging, leadership, advancement, and accountability. Structural racism and other forms of systemic inequity continue to limit opportunity across the health professions education and healthcare institutions.

Lasting change requires not only supporting diverse leaders, but also strengthening connections among educational institutions, healthcare organizations, professional associations, accrediting and credentialing bodies, students, advocates, community actors, and others within the health professions ecosystem, whose relationships, actions, practices, and mindsets shape health outcomes for the communities they serve. These relationships create the support, trust, shared learning, and coordinated action necessary to advance DEIB and build a more equitable healthcare system. 

The Buchanan County Community Foundation Grants aim to enhance the quality of life in Buchanan County, Iowa, by providing funding for various projects that benefit the community. This includes support for arts, education, health, and community betterment initiatives. Eligible applicants must be 501(c)(3) organizations or government entities, with grants ranging from $1,000 to $20,000. The foundation prioritizes projects that involve community engagement and demonstrate sustainability without ongoing financial dependence.

The East Texas Estate Planning Council Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors pursuing careers in accounting, law, finance, banking, investments, insurance financial planning, or philanthropic planning. This scholarship reflects a commitment to education and aims to alleviate financial barriers for students in East Texas. Applicants must demonstrate financial need, with FAFSA required, and can attend any college in the United States for one year.

The John M. O'Quinn Foundation Grant, established in 1986, has contributed over $192 million to various charitable activities, focusing primarily on Houston and its surrounding areas. The Foundation supports tax-exempt organizations and governmental units, emphasizing conservation, education, healthcare, and programs for underprivileged youth. Grants are not available for type III supporting organizations, individuals, or foreign charities, ensuring a targeted impact within the local community.

The Katie Cannon Scholarship honors Rev. Dr. Katie Geneva Cannon, a pioneering figure in the Presbyterian Church (U.S.A.). This scholarship aims to empower Presbyterian women of color, clergywomen, and college women by providing financial assistance for leadership development events and educational opportunities. It promotes spiritual growth and mission involvement within the church, ensuring that women are equipped for greater service and leadership roles. This fund is part of the Women's Ministry Fund at the Presbyterian Mission Agency.

August Corso Scholarship Fund

Scholarships shall be awarded to residents of Erie County, Ohio pursuing a post-secondary education. Preference shall be given to students pursuing a degree in Horticulture, Environmental Science or Agricultural Business. Financial need is a consideration for the scholarship award.

Scholarships are available for students planning to attend an accredited nonprofit college or university, or planning to receive licensure, accreditation, or a certificate from a nonprofit vocational or apprenticeship program in the United States.

The scholarship may be renewed for a second, third, and fourth year.

The Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership (ESSSP) aims to enhance NOAA's mission through collaborative research and activities. It focuses on understanding changes in Earth's systems and their impacts on ecosystems and communities. Eligible applicants include academic institutions offering doctoral degrees in NOAA-related sciences. The total funding available is approximately $10 million, supporting initiatives that encompass research, data evaluations, and stakeholder engagement.

The Winnebago County Community Foundation provides grants aimed at improving the quality of life in Winnebago County, Iowa. Focused on community betterment, education, health, and environmental initiatives, the foundation supports 501(c)(3) nonprofits and government entities. With a minimum grant request of $1,000, it prioritizes projects that address community needs and demonstrate sustainability. Organizations can only submit one application, ensuring a fair review process for all applicants.

The Northeast Sea Grant Consortium and NOAA’s Northeast Fisheries Science Center invite proposals to explore the interactions between fishing communities and offshore wind development in the U.S. Northeast. This initiative aims to enhance understanding of community resilience and economies, while fostering collaborative research that informs decision-making. Proposals should utilize qualitative and quantitative methods and involve at least one Co-PI from the six states of the NESGC, with a requirement for a 25% non-federal match.

About Us

The Food Allergy Fund is the leading nonprofit dedicated to funding food allergy research. FAF's grants support the creation of new treatments that will address the root causes of food allergies. Through our ground-breaking research and unique thought leadership summits, we accelerate innovation to find solutions.

Food Allergy Fund Drug Repurposing Program

Grants will be awarded to research teams that propose innovative approaches to repurposing therapeutics for the prevention or treatment of food allergy. We would welcome proposals identifying either an existing FDA-approved drug or drug in development with human safety data that has a rationale for the prevention of food allergies, prevention or treatment of food induced anaphylaxis, or an improved method for maintaining food allergic tolerance in previously allergic patients.

We are particularly interested in either small molecule drugs or biologicals that have well defined mechanisms of action that provide a scientific rationale for use in food allergies. Examples could involve drugs such as enzyme inhibitors or immunomodulators with specific activities that lend themselves to alter intestinal, mucosal or immune function.

The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.