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Best Operating Grants for Nonprofits in Iowa

Find the perfect Operating grants for nonprofits in Iowa on Instrumentl. 10,000+ Operating grants for nonprofits in Iowa in the United States.

10,000+

Available grants

$2.56B

Total funding

$5K

Median grant

10,000+ grants
$2.56B total
$5K median

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9,587 Results based on applied filters

Small Discretionary Grants

Reader's Digest Partner for Sight Foundation
Private
United States
US $5,000 - US $10,000

Reader’s Digest Partners for Sight Foundation

The Reader’s Digest Partners for Sight Foundation is a philanthropic organization dedicated to improving the lives of individuals who are blind or visually impaired by fostering independence and self-sufficiency. Its mission is to support programs that help people with vision loss lead independent, productive lives, while its vision is an accessible and inclusive world where individuals have the tools, resources, and opportunities to fully participate in society.

The Foundation’s funding priorities focus on supporting nonprofit organizations and initiatives that provide education, training, and rehabilitation services, assistive technology innovations, vision care and access to aids, and capacity building for professionals serving the visually impaired community. It also invests in programs that enhance employment opportunities, promote independence, and improve service delivery systems for people with vision loss, emphasizing practical, community-based solutions and long-term impact.

Small Discretionary Grants

The Reader’s Digest Partners for Sight Foundation (RDPFS) Track #3 Small Discretionary Grants provide flexible, year-round funding for smaller-scale initiatives that support individuals who are blind or visually impaired. Grant requests are accepted on a rolling basis and awarded at the discretion of the Executive Director. Awards are made until available funds are exhausted, allowing the Foundation to respond to timely or emerging needs.
Workforce Preparation & Job Readiness Vision Impairment Care & Services Business Development +1 more

Elizabeth Pastor Ashland University Music Education Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Elizabeth Pastor Ashland University Music Education Scholarship supports music students at Ashland University, honoring the legacy of Elizabeth Pastor, a renowned pianist and educator. This scholarship aims to assist students pursuing a music-related career, reflecting Pastor's belief in the transformative power of art. Established through her estate plan, it embodies her commitment to fostering musical talent and enriching the community through education and the arts.
Education - Higher Education Academic Scholarship Programs Music Education +2 more

Native Public Health Resilience

Indian Health Service
Federal Government
United States
Unspecified amount
The Native Public Health Resilience (NPHR) program is a new funding opportunity aimed at supporting Tribes and Tribal Organizations in delivering essential public health services. Sponsored by the Indian Health Service, this initiative seeks to bolster public health infrastructure and resilience within tribal communities, ensuring they have the necessary resources to address health challenges effectively. Eligible applicants will receive financial assistance to enhance their public health capabilities and improve community health outcomes.
Epidemiology & Public Health Health Care Access & Delivery Native American Services +2 more

Single Program Grants

Reader's Digest Partner for Sight Foundation
Private
United States
US $25,000 - US $50,000
The Reader’s Digest Partners for Sight Foundation offers Single Program Grants to support impactful programs for individuals who are blind or visually impaired. These grants, ranging from $25,000 to $50,000, prioritize initiatives that enhance independence and service delivery. Eligible organizations must be US 501(c)(3) non-profits, and unsolicited proposals are not accepted. The foundation emphasizes community-based solutions and invites qualified applicants to submit a Letter of Inquiry followed by a full proposal.
Workforce Preparation & Job Readiness Vision Impairment Care & Services Business Development +1 more

AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer (Fund B)

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty in digestive disease research. This award aims to support independent careers in pancreatic cancer research by protecting a significant portion of the recipient's time for research activities. Eligible applicants must hold an MD, PhD, or equivalent and work at a North American institution, with AGA membership required. Strong encouragement is given to underrepresented groups.
Pancreatic Cancer

AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer (Fund A)

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty focused on independent research in pancreatic cancer. This award aims to protect at least 50% of the recipient's time for research activities. Eligible applicants must hold an MD or PhD and be classified as early-career. The award encourages physician-scientists and underrepresented groups in biomedical research to apply, supporting innovative research that can lead to significant advancements in understanding pancreatic cancer.
Pancreatic Cancer

Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The upcoming National Institute of Mental Health (NIMH) funding opportunity aims to explore the effects of HIV immunotherapies on central nervous system (CNS) outcomes. It seeks to identify mechanisms, benefits, and risks associated with these therapies, focusing on overcoming CNS-specific barriers. The initiative encourages collaborations to develop strategies for achieving sustained virologic remission and improving neurological outcomes for individuals with HIV, particularly targeting neurotoxicity and neuroinflammation.
HIV / AIDS

The Save Mart Companies CARES Foundation Grant

Save Mart Cares
Private
California, Oregon +2 more
US $500 - US $10,000

About

With deep roots in California’s Central Valley, The Save Mart Companies and its family of stores prides itself in being a part of neighborhoods and putting people first. Our dedication to customers is reflected in the connections we’ve made in the communities we’ve served for more than 70 years.

The Save Mart Companies CARES Foundation

In 2000, we established The Save Mart Companies CARES Foundation, our philanthropic, non-profit organization, supporting programs and organizations that provide vital resources for children and families in the communities we serve. The CARES Foundation focuses on building stronger communities through fresh foods, accessibility, and programs that support youth and helping them to thrive. Annually, The CARES Foundation contributes approximately $500,000 in small grants to support community-based, non-profit organizations.

The Save Mart Companies CARES Foundation Grant

The CARES Foundation’s focus is building stronger communities through fresh foods, access to food, and programs that support youth and helping them thrive.

The CARES Foundation will review, on a quarterly basis, among other things, the breadth of the audience served; the likely impact in the community; the importance of the need to be addressed in the community; and the community reputation, service history, and financial stability of the group or program seeking funds. No one of these or other factors will necessarily be weighted more heavily than another. Instead, each group or program will be measured against all groups and 2 programs seeking funding at the time. For example, a program serving a small segment of the community but that addresses an especially important community need, and thus has the potential for a strong and meaningful impact, would be favored over a group serving a wider clientele but that fills a less important community need. Requests for Grants should be a minimum of $500.00 up to $10,000.00. Programs and organizations requesting smaller grants should contact the Store Manager of the nearest Save Mart Companies’ store location for request consideration.

Recipients that receive grants for more than one year must demonstrate meaningful outcomes for the previous investment made by The CARES Foundation.

Food Access & Hunger Youth Services Family Services +1 more

Emma E. Hill Memorial Scholarship Fund

Chester County Community Foundation
Private
United States
Unspecified amount

Emma E. Hill Memorial Scholarship Fund

Mission Statement

The Emma E. Hill Memorial Scholarship Fund was established to memorialize Emma by helping female swimmers pursue their dreams of a college education. The scholarship awards will be granted on an annual basis to female graduating high school senior athletes in Southern Chester County.

About Emma

Emma was an excellent student as a sophomore at Unionville High School (UHS). She loved to swim and was a dedicated member of both the Kennett YMCA Sea Dragons and UHS swim teams. In her spare time, Emma was a lifeguard and also taught young children how to swim at the Y. As a younger child and teenager, Emma excelled on the ballfield in URA softball.

At the young age of 16, Emma passed away following complications caused by a rare type of gastric cancer, a form of the disease that was unheard of in a child and unfortunately found too late. Throughout Emma’s brief illness, she was strong and determined to get better, and did not let her health issues define her in any way.

Emma was beautiful in every sense of the word, and was loved throughout her community and beyond. She worked hard at whatever she was trying to accomplish, but always with a cheery, exuberant attitude and lovely smile. More than anything, her absolute kindness and warm heart are what made Emma our sweet girl.

Education - Higher Education Women & Girl Services Swimming +2 more

Patrice Faye Cohen Memorial Scholarship Award

Jewish Community Foundation
Private
United States
Unspecified amount
The Patrice Faye Cohen Memorial Scholarship Award supports high school women from Southern New Jersey who are pursuing college education with a focus on entrepreneurship. Established in memory of Patrice Faye Cohen, a successful business owner, this scholarship aims to empower women to achieve their entrepreneurial dreams. Eligible candidates must demonstrate a commitment to their studies and entrepreneurial aspirations, with financial support available for tuition and related expenses.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Spearfish Volunteer Firefighters' Association Scholarship

South Dakota Community Foundation
Private
United States
Unspecified amount

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Scholarships

At South Dakota Community Foundation (SDCF), we proudly manage more than 350 scholarship funds in partnership with generous donors who are committed to supporting students. These scholarships offer countless opportunities to help ease the financial burden of continuing their education.

Spearfish Volunteer Firefighters' Association Scholarship

To provide financial support to individuals pursuing an education and training in the public safety industry.

The Spearfish Fire Department, established in the late 1880s as a volunteer organization, serves the northern Black Hills in western South Dakota. Its mission is to protect lives and property within the fire protection district and mutual aid area. Additionally, the department advocates for fire safety and provides fire safety education in local schools and the wider community.

Education - Higher Education Vocational & Trade Education Fire Ecology +1 more

Independent Living Initiatives

Music Movement
Association/Society
United States
US $1,500 - US $5,000
Music Movement's Independent Living Initiatives grant supports individuals with Autism and developmental differences in the U.S. Grants, typically ranging from $1,500 to $5,000, aid in various areas including independent living, camps, and continued education. Applicants must be legal guardians of eligible individuals aged 18 and older. The grant portal will reopen for submissions on March 28, 2026, encouraging early review of guidelines to ensure complete applications.
Music Autism Physical Therapy

Instrument Donations Program

Music Movement
Association/Society
United States
US $500 - US $1,500 in in-kind support
The Instrument Donations Program by Music Movement supports children and young adults with Autism and learning differences by providing funding for musical instruments. This initiative fosters self-expression, personal growth, and emotional well-being through music. Grants typically range from $500 to $1,500 and are available to applicants within the United States. The program encourages artistic development and enhances social skills, making a significant impact on the lives of those facing developmental challenges.
Music Autism Children With Disabilities

Incyte Healthcare Sponsorships

Incyte Corporation
Corporate
United States
Unspecified amount
Incyte Corporation, a biopharmaceutical leader, offers healthcare sponsorships to support organizations focused on improving patient care and access to healthcare information. Eligible applicants include medical schools, associations, non-profits, advocacy groups, and hospitals. Requests should align with Incyte's commitment to enhancing the lives of patients affected by cancer and other diseases, ensuring compliance with regulatory guidelines. Organizations must enter a written agreement with Incyte to receive funding.
Cancer / Oncology Diseases & Conditions Nursing +2 more

Music Therapy Grants

Music Movement
Association/Society
United States
US $1,500 - US $2,500
Music Movement offers grants for music therapy aimed at children and young adults with Autism Spectrum Disorder (ASD) and other developmental challenges. Grants typically range from $1,500 to $2,500, providing financial relief to families seeking therapeutic resources. Eligible applicants include legal guardians of children in the U.S. who select qualified therapists. The organization focuses on enhancing communication, social skills, and emotional well-being through music, benefiting diverse communities and promoting personal growth.
Autism Children With Disabilities Music Education

Margaret Thorne-Dilley Scholarship for Science Teachers Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Margaret Thorne-Dilley Scholarship for Science Teachers Scholarship

Eligibility

Equally weighted as a need and merit based award for a Raleigh County high school graduate with a 3.5 cumulative GPA; Pursuing baccalaureate degree in education at an accredited institution; Preference will go to students pursuing a science field including the biological, physical and natural sciences. If none apply with the preferences listed, mathematics will also be considered.

Education Educational Access & Equity Education - Higher Education +5 more

Cecelia Springmeyer Memorial Scholarship

Decatur County Community Foundation Inc.
Private
United States
More than US $1,000
The Cecelia Springmeyer Memorial Scholarship, managed by the Decatur County Community Foundation, aims to support North and South Decatur students pursuing post-secondary education in law enforcement, criminal justice, animal husbandry, agronomy, or teaching. Applicants must reside within the Decatur County Community Schools district and may receive a minimum scholarship of $1000 to ease their educational costs. For more details, visit ndsdscholarships.com.
Academic Scholarship Programs Education - Higher Education Law +5 more

Pat and John MacTavish Fund

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The Pat and John MacTavish Fund, established in 2007 by John Mac Tavish in memory of his wife Pat, provides scholarships aimed at encouraging young women to pursue higher education in the hard sciences. Awarded by the Grand Haven Area Community Foundation, scholarships are competitive and based on criteria such as financial need and academic achievement. Applicants from Northern Ottawa County or specific school districts are eligible. The fund emphasizes the importance of education in fields such as math, chemistry, and computer science.
Education - Higher Education Educational Access & Equity Computer Science & Engineering +6 more

LabCorp Charitable Foundation Grants

Labcorp Charitable Foundation
Private
United States
Unspecified amount
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Education Community Services Health & Medicine +5 more

Strategic Projects: Program & Staff Grants

M J Murdock Charitable Trust
Private
United States
More than US $50,000
The M J Murdock Charitable Trust offers the Strategic Projects: Program & Staff Grants to support nonprofits in the Pacific Northwest. These grants focus on capacity-building for mission-driven projects and infrastructure investments. Eligible organizations must demonstrate a commitment to community flourishing, with funding available for new programs or expansion of existing ones. The Trust prioritizes initiatives that align with its strategic goals, fostering sustainable nonprofit growth and impact in the region.
Art & Culture Education Community Services +6 more

Exemplary Pathways to STEM Graduate Education: Planning

Alfred P Sloan Foundation
Private
United States
Up to US $75,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs. By addressing barriers in graduate education, the initiative seeks to promote equitable learning environments. Planning grants will support collaborations that assess needs and develop systemic changes to enhance pathways for students in STEM fields, ensuring that all students can thrive in their academic pursuits.
Astronomy & Astrophysics Biology Chemistry +10 more

Exemplary Pathways to STEM Graduate Education: Seed

Alfred P Sloan Foundation
Private
United States
Up to US $250,000
The Alfred P. Sloan Foundation's initiative, "Creating Equitable Pathways to STEM Graduate Education: Seed," aims to enhance graduate education access for students from Minority Serving Institutions (MSIs). The program provides grants of up to $500,000 to foster partnerships between MSIs and various higher education institutions. Projects should focus on overcoming barriers to success in graduate studies, including recruitment and admission processes, thereby promoting equitable learning environments in STEM fields.
Astronomy & Astrophysics Biology Chemistry +10 more

The Slomo and Cindy Silvian Foundation Grant

Slomo And Cindy Silvian Foundation Inc
Private
United States
Unspecified amount
The Slomo and Cindy Silvian Foundation Grant supports a range of subjects including education, children's welfare, medical care, medical research, and Jewish philanthropic endeavors. Established in honor of Cindy Silvian, the foundation has awarded over $30 million since 2008. Applications are by invitation only, and organizations must meet specific eligibility criteria to be considered for funding. This year, the foundation allocated over $2.4 million to more than 110 organizations, highlighting its commitment to impactful philanthropy.
Education Health & Medicine Child Welfare Services +5 more

Exemplary Pathways to STEM Graduate Education: Implementation

Alfred P Sloan Foundation
Private
United States
Up to US $500,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs to enhance equitable learning environments. Grants of up to $500,000 will support projects addressing systemic barriers, promoting effective practices, and ensuring seamless transitions from MSIs to advanced degrees in various STEM fields. The initiative seeks to create lasting impacts on student access and success in graduate education.
Astronomy & Astrophysics Biology Chemistry +10 more

Zimmerman, Edward and Beverly Memorial Scholarship Fund

Noble County Community Foundation
Private
United States
US $1,000
The Zimmerman, Edward and Beverly Memorial Scholarship Fund offers $1,000 to West Noble High School seniors pursuing higher education at a college or university, with priority given to those demonstrating community service and maintaining a GPA between 2.50 and 3.00. Preference is also given to students studying agriculture, education, social work, or accounting. This scholarship reflects the values of its donors, Edward and Beverly, who were dedicated community members and supporters of local education.
Mathematics Education Human & Social Services +5 more

Strategic Projects: Equipment & Technology Grants

M J Murdock Charitable Trust
Private
United States
More than US $50,000
The M J Murdock Charitable Trust offers Strategic Projects: Equipment & Technology Grants to nonprofits in the Pacific Northwest. These grants focus on capacity-building projects and essential equipment, requiring recipients to cover at least 50% of costs. Eligible organizations include 501(c)(3) nonprofits and tribal entities. Priority is given to projects enhancing community services, education, and environmental stewardship, supporting initiatives that foster human flourishing and demonstrate diversified funding.
Art & Culture Education Community Services +6 more

Strategic Projects: Capital Grants

M J Murdock Charitable Trust
Private
United States
More than US $100,000
The Strategic Projects: Capital Grants by the M J Murdock Charitable Trust offer vital funding opportunities for nonprofit organizations in the Pacific Northwest. These grants support transformative projects that enhance community well-being through construction, renovation, and infrastructure investments. Eligible entities include 501(c)(3) nonprofits and government entities. The Trust emphasizes projects that demonstrate strong community impact and funding diversification, ensuring sustainable growth and lasting benefits for the communities served.
Nonprofit Growth & Development Art & Culture Education +6 more

Operating Grants for Nonprofits in Iowa Highlights

Looking for operating grants for nonprofits in Iowa?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Iowa recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Iowa

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Operating grants for nonprofits in Iowa grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Operating grants for nonprofits in Iowa over $25K in average grant size

37 Operating grants for nonprofits in Iowa over $50K in average grant size

33 Operating grants for nonprofits in Iowa supporting general operating expenses

100+ Operating grants for nonprofits in Iowa supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Health & Medicine

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Iowa?

Most grants are due in the first quarter.

Q1
30.7%
Q2
24.4%
Q3
22.2%
Q4
22.7%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Iowa?

Grants are most commonly $18,750.

$500 $500 Min.
$18,750 $18.8 K Median
$195,866 $195.9 K Average
$3,000,000 $3 M Max.

Average Grant Size

What's the typical amount funded for Iowa?

Grants are most commonly $82,635.

$82,635

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Iowa year over year?

In 2024, funders in Iowa awarded a total of 28,032 grants.

2022 25,336

2023 26,582

2024 28,032

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Iowa given out in Iowa, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Iowa changing over time?

Funding has increased by 9.41%.

2022 $2,079,026,768

2023 $2,108,613,200
1.42%

2024 $2,307,128,111
9.41%

Iowa Counties That Receive the Most Funding

How does grant funding vary by county?

Polk County, Story County, and Johnson County receive the most funding.

County Total Grant Funding in 2024
Polk County $545,560,005
Story County $266,280,101
Johnson County $184,865,698
Linn County $166,016,288
Boone County $155,314,892