Best Unrestricted Grants for Nonprofits in Iowa

The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.

The Alliance for Innovation on Maternal Health (AIM) Capacity Program aims to enhance the capacity of state, territorial, and Tribal entities in the U.S. to implement and sustain AIM Patient Safety Bundles. By promoting evidence-based maternal safety practices, the program strives to improve the quality of maternity care, enhance maternal health outcomes, and significantly reduce preventable maternal mortality and severe morbidity.

The OREF/MTF Biologics Research Grant encourages innovative research in biologics, focusing on reconstruction, bone regeneration, and transplantation, including stem cells. It is open to licensed U.S. orthopaedic surgeons and PhD researchers with faculty appointments. The grant seeks clinically relevant projects that demonstrate practical applications and multidisciplinary collaboration, promoting excellence in research. New investigators are especially encouraged to apply, ensuring a commitment to advancing orthopaedic science.

About Colin Farrell FoundationThe Colin Farrell Foundation is committed to transforming the lives of individuals and families living with intellectual disability through education, awareness, advocacy, and innovative programs. Inspired by his two sons, he is excited and deeply humbled by the hope that the Colin Farrell Foundation can help those who the larger systems of governance have neglected.

CFF Innovation GrantsWe’re looking for bold, scalable solutions focused on one or more of these priority areas:

• Affordable co-housing models for individuals and families
• Employer-partnered day programs and inclusive job opportunities
• Tools and technologies that enhance accessibility at home and in community spaces
• Cross-sector collaborations between public, private, and nonprofit organizations

The Mastercard Strive USA 2025 Innovation Fund aims to enhance the financial health of small businesses across the U.S. by providing up to $250,000 in grants to organizations developing innovative solutions. This initiative focuses on addressing challenges such as limited access to financial resources and vulnerability to economic shocks, ultimately fostering resilience and growth within the small business sector.

The Harry Kramer Memorial Fund Grant supports U.S. charitable organizations that assist individuals and institutions in Israel, focusing on welfare, healthcare for the sick and aged, and education in South Florida. Founded by Harry A. Kramer, a successful entrepreneur and veteran, the fund reflects his deep commitment to charitable causes. Organizations must qualify under Section 501(c)(3) and meet specific eligibility criteria to apply for funding, ensuring that aid reaches those in need.

• Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
• Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
• Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
• Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.

About the Foundation

Mission

The Hoover Presidential Foundation strengthens the Herbert Hoover Presidential Library and Museum and Herbert Hoover National Historic Site by inspiring leadership, service, and civic responsibility grounded in the Hoovers’ life and values.

Vision

A future where Herbert Hoover’s uncommon legacy inspires generations to live with purpose, serve with compassion, and create lasting civic impact.

School Bus Travel Grant

Receive a Grant to Visit the Hoover Campus

The Hoover School Bus Travel Grant provides funds to help schools meet the transportation costs of educational field trips to the Herbert Hoover Presidential Library and Museum and Herbert Hoover National Historic Site. While we would like to cover all the costs of visits to the Hoover Campus, these funds are intended to subsidize travel costs. The program, funded entirely through contributions from private individuals, corporations, and foundations, is specifically intended to promote public education about and appreciation for Herbert Hoover.

The Hays, Karla, Loving Heart Scholarship offers financial support to graduating seniors of Beatrice High School, with one to three scholarships available totaling up to $1,000. Administered by the Beatrice Educational Foundation, this initiative aims to assist deserving students in pursuing higher education. The foundation, established in 1987, supports academic achievement and civic involvement in the community. Eligible students must maintain a minimum GPA of 3.0 and demonstrate ethical scholarship application practices.

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Fruit of the Vine Scholarship

The Fruit of the Vine Scholarship Fund benefits graduating Napa County high school seniors and Napa Valley College transfer students who will find the cost of higher education a financial hardship. Consideration is given to applicants who are the first in their family to attend college or are employed (or have a parent or guardian who is employed) in the Napa County wine or grape industry. Recipients of the scholarship will receive funding for up to four years of undergraduate study.

The Jurgens, Virgil Scholarship, funded by the Beatrice Educational Foundation, offers a $375 award to a Beatrice High School senior who excels in baseball and ranks in the top 25% of their class. The Foundation, established in 1987, provides financial support for educational opportunities. This scholarship aims to assist deserving students in pursuing higher education, emphasizing the importance of academic achievement and community involvement.

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Never Let Go Fund

The purpose of the Never Let Go Fund is to provide funds to qualified individuals to cover expenses related to the treatment of childhood cancer. Grant requests will be considered for children under the age of 18.

This project aims to enhance health outcomes for women living with HIV in the South by integrating HIV care with comprehensive women's health services through coordinated Clinic and Community Collaboratives. By funding organizations to implement targeted strategies such as culturally responsive services and learning collaboratives, the initiative seeks to improve access to essential health services, increase the number of women initiating rapid ART, and foster sustainable healthcare models that address the unique needs of this population.

The Friends Foundation for the Aging Grant supports innovative and impactful programs aimed at addressing the needs of older adults, particularly within underserved populations. This Quaker foundation prioritizes collaboration and sustainability in its funding efforts. Eligible applicants must be 501(c)(3) public charities focused on enhancing the quality of life for aging individuals. Grants are typically awarded for one year and target organizations that align with the foundation's mission and values.

The Gifford Pinchot Medal, awarded by the Society of American Foresters, honors exceptional contributions by forestry professionals in North America. Recognizing achievements in administration and practice, this medal is presented every odd-numbered year at the SAF national convention. Recipients receive a $500 honorarium, complimentary registration, and up to $500 for travel expenses. This prestigious award highlights the importance of leadership and innovation in the forestry profession.

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.

The SAF National Awards Program recognizes exceptional contributions to forestry through its Honorary Membership award. This accolade is presented to individuals whose impact on the field is acknowledged by their peers, highlighting their distinguished service in advancing forestry knowledge and societal awareness. Awardees receive lifetime membership in SAF along with complimentary convention registration. The program seeks to honor those, including non-professional foresters, who have made significant strides in forestry, both domestically and internationally.

The SAF National Awards Program includes the John A. Beale Memorial Award, recognizing exceptional voluntary service in forestry by SAF members. Established to honor John Beale's legacy, this award is presented at the SAF national convention and includes a $500 honorarium, complimentary registration, and up to $500 for travel expenses. Nominees must demonstrate sustained commitment to the SAF and its mission, showcasing leadership and promotion of forestry principles.

The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.

The Young Forester Leadership Award, presented by the Society of American Foresters (SAF), recognizes exceptional leadership from young forestry professionals under 40 years old. This award highlights contributions to forestry through innovative projects and sustained leadership roles. Recipients receive a $500 honorarium, complimentary registration for the SAF national convention, and support for travel expenses up to $500. This prestigious accolade aims to encourage the next generation of forestry leaders to excel in their professional endeavors.

The American Heart Association is inviting proposals for research on the effects of GLP-1 and GIP agonists in individuals with cardiovascular, kidney, and metabolic diseases. This initiative aims to explore how these medications can alleviate the CKM burden. Researchers with expertise in causal inference, machine learning, and cardiovascular research are encouraged to apply, particularly those working in multidisciplinary teams and leveraging various data sources.

Gilead Sciences

At Gilead, we are relentlessly committed to advancing transformative therapies for the most serious diseases, delivering an exponentially positive impact on health.

For more than three decades, we have combined scientific rigor with a deep sense of purpose to improve health outcomes and reimagine care. Our work spans more than 35 countries with a focus on three therapeutic areas: virology, oncology, and inflammation, where unmet medical needs remain greatest.

From individual patients to whole populations, we’re committed to delivering healthier futures for people and communities worldwide.

Our Mission: To discover, develop and deliver innovative therapeutics for people with life-threatening diseases.

HIV Prevention NOVA 2026

Program Description

Gilead Sciences invites research proposals that advance the evidence base for innovative and scalable models of delivery for long-acting (LA) HIV pre-exposure prophylaxis (PrEP) in the United States.

This Topic of Interest (TOI) is focused on care delivery models implemented in non-traditional settings, defined as clinical and non-clinical environments where PrEP services are not routinely provided. Emphasis is placed on approaches that reflect real-life practice and address gaps in current PrEP delivery infrastructure.

Persistent inequities in PrEP uptake in the U.S. suggest that expanding availability within traditional clinical settings alone is unlikely to reach all populations with unmet PrEP need.1,2 Rigorous implementation studies in non-traditional settings where PrEP services are not routinely provided are needed to evaluate whether these models can reduce access barriers and improve equitable reach among individuals who may benefit from PrEP.2,3,4

The goal of this TOI is to generate practical, decision-relevant evidence that informs how LA PrEP can be implemented, scaled, and sustained in real-life U.S. settings.

The ASSP Foundation Academic Scholarships provide vital financial support to students in environmental health and safety programs. With over $6 million awarded since 1990, the foundation aims to enhance career prospects through education and leadership development. In the 2024-2025 academic year, $215,000 was allocated to 117 recipients, fostering a sustainable talent pipeline in EHS. This initiative not only promotes the profession but also ensures a safer future for workers by encouraging new talent to enter the field.

The Implementing Zero Suicide in Health Systems program aims to enhance suicide prevention efforts for adults within health systems. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this initiative employs a comprehensive approach that incorporates all seven elements of the Zero Suicide framework: Lead, Train, Identify, Engage, Treat, Transition, and Improve. This program seeks to create safer health environments and reduce suicide rates effectively.

The FY2026 Cooperative Agreement for the 988 Suicide & Crisis Lifeline Administrator aims to enhance and manage the 988 Lifeline, connecting individuals in crisis through various communication methods to a network of certified crisis centers. This initiative seeks to link people with vital emergency, behavioral health, and social services, providing essential support to those in need. The program is funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), emphasizing mental health resources and accessibility.

The Helen M. Heitmann Young Scholar Award, presented by SHAPE America, honors young professionals who have made significant contributions to research in curriculum and instruction within health and physical education. Eligible candidates must be current SHAPE America members and have 3 to 6 years of experience post-doctorate. This award emphasizes active involvement and scholarship in the field, encouraging innovative research that enhances educational practices for preK-12 students.