Best Large Grants for Nonprofit Organizations in Maine

The New England Food Vision Prize aims to enhance local food supply chains in New England's educational institutions by awarding up to $1.5 million. The program supports innovative projects that increase the amount of regionally produced food served to K-12 and college students. By fostering collaboration among schools, farmers, and community organizations, the Prize strengthens food systems while prioritizing access for students and communities with limited fresh food options.

The Les Mehrhoff Botanical Research Award, established by the New England Botanical Society, supports innovative botanical research that enhances our understanding of New England's flora. Open to applicants without membership, it prioritizes projects lacking traditional funding sources. Eligible expenses include fieldwork, lab supplies, and moderate stipends. This award encourages researchers to explore unconventional inquiries and fosters a deeper appreciation for the diverse plant life in northeastern North America.

What does this program do?

It provides loans and grants to Microenterprise Development Organizations (MDOs) to:

• To help microenterprises startup and growth through a Rural Microloan Revolving Fund.
• Provide training and technical assistance to microloan borrowers and micro entrepreneurs.

Friends of NRA

Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.

Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.

Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.

Friends of NRA State Fund Grant Program - Maine

The Friends of NRA State Fund Grant Program provides supplies, equipment, and financial support to a variety of qualified groups and programs at the local level; geared towards youth, women, law enforcement, veterans, the disabled, and the general public, including:

• General shooting programs
• Competitive shooting
• Education, training and safety
• Hunting and conservation
• Community outreach
• Historical education

Grant funding must be used to further a charitable purpose as defined by the Internal Revenue Code under section 501(c)(3) and accompanying rules, regulations, and other IRS law and materials.

The Agricultural Leadership Grant, administered by Maine Agriculture in the Classroom (MAITC), supports leadership development for students enrolled in agricultural courses at Middle and High School levels. With grants of up to $1,000, the program emphasizes organized leadership activities over individual funding. Established in 2007, MAITC aims to enhance students' understanding of agriculture's role in society, benefiting over 77,000 students last year through various educational initiatives.

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

The NEBC Graduate Student Research Award offers up to $3,000 to support graduate students conducting botanical research on New England's flora, including plants, algae, and fungi. This award encourages projects involving field, lab, and herbarium work, as well as travel within the region. Open to all graduate students, it aims to foster significant contributions to systematic botany, plant ecology, genetics, and conservation biology.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Karen Colina Wilson Foundation Grant supports programs for children, youth, and women, enhancing their health and well-being through education, art, literature, and music. Established in 2006, the foundation aims to make a positive difference in their lives, particularly in Southern and Western Wayne County, Michigan. Grants typically range from $500 to $10,000, often as matching funds, fostering broader fundraising efforts by local nonprofit organizations.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Maine Women's Fund (MWF) Grant, administered by the Maine Community Foundation, supports organizations dedicated to improving the lives of women and girls in Maine. With funding of up to $15,000 per year, grants are available for general support of programs that promote financial literacy, health education, leadership development, and policy advocacy. Organizations must be located in Maine and engage women and girls as primary beneficiaries. Applications will be accepted in 2025 and 2027.

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

The Ronald P. Guerrette FFA Scholarship Fund, established in 1998 by friends and family, honors Ronald P. Guerrette of Caribou. This fund awards a $1,000 scholarship annually to graduating high school seniors in Maine who are FFA members and are committed to pursuing careers in farming or agriculture-related fields. The Maine Community Foundation, founded in 1983, supports this initiative by providing resources for educational opportunities across the state.

Department of Economic and Community Development

At DECD, we are more than two dozen experts whose broad mission is to help communities and businesses prosper through a variety of programs providing everything from targeted tax relief to community block grants to tourism marketing. Whether your business wants to make a film here, bring a Maine-made product to market, expand an aquaculture project, or explore financing when moving a business to our state, our experienced staff can help.

Community Development Block Grant (CDBG) Program 

In 1982 the State of Maine began administering the CDBG Program to assist units of local government in various community projects in areas ranging from infrastructure, housing, downtown revitalization to public facilities and economic development.

CDBG Objectives

All CDBG funded activities must meet one of three National Objectives of the program. These objectives are:

• Benefit to low- and moderate-income persons.
• Prevention and/or elimination of slum and blight conditions; and
• Meeting community development needs having a particular urgency

The Maine CDBG Program serves as a catalyst for local governments to implement programs which meet one of the three National Objectives, and:

• Are part of a long-range community strategy, or State of Maine Strategic Economic Development Plan
• Improve deteriorated residential and business districts and local economic conditions
• Provide the conditions and incentives for further public and private investments
• Foster partnerships between groups of municipalities, state and federal entities, multi-jurisdictional organizations, and the private sector to address common community and economic development problems; and
• Minimize development sprawl consistent with the State of Maine Growth Management Act and support the revitalization of downtown areas.

CDBG Home Repair Network Program (HRN)

The Home Repair Network Program (HRN) provides funding statewide to address housing problems of low- and moderate-income persons. This program will provide housing rehabilitation services administered on a regional basis throughout Maine.

Eligible Activities

Eligible activities under the HRN Program are rehabilitation of occupied or vacant single-family or multi-family housing units, demolition, same site replacement housing, provision of potable water and sewer, energy conservation, removal/mitigation of lead-based paint, asbestos, radon, or other hazardous material, removal of architectural barriers and the Critical Access Ramp Program (via Alpha One).

The 2025 Giving Project Fund for Community Organizing aims to empower community-led movements in Maine, providing unrestricted support of up to $20,000 for at least five groups. This participatory grantmaking initiative, guided by a diverse cohort of donor-organizers, focuses on advancing justice in economic, environmental, racial, and social spheres. By prioritizing organizations that utilize community organizing as a strategy, the fund seeks to foster equity and address systemic issues faced by marginalized communities.

The Joseph & Dorothy Headley Scholarship supports Maine's nontraditional students, providing financial assistance for those pursuing post-secondary education after facing various life challenges. Eligible applicants must be Vinalhaven residents for three years, display good character, and demonstrate financial need. The scholarship aims to empower individuals over 25, those working full-time, or financially independent students. By easing financial burdens, this initiative encourages adult learners to focus on their educational goals and enhance their lives through training and education.

About

Being deeply connected to the community means more than providing access to excellent healthcare. It means understanding, and investing in, the health needs of our community.

Through our Community Investment Fund (CIF), Endeavor Health has awarded more than $38.5 million to 59 local partnerships dedicated to enhancing community health and wellbeing, advancing health equity and supporting local economic growth. Together, we’re committed to helping everyone in our communities be their best.

Award categories

Through the CIF, we will make meaningful and intentional investments through impact awards and capacity builder awards. These awards are intended to meaningfully advance the health of our community over time towards three bold aspirations through investments in five areas of focus.

We aspire to a future where:

• A person’s zip code does not determine how long they will live
• Hunger and homelessness in our communities are history
• The healthcare workforce is thriving and representative of the communities we serve

To help advance these aspirations, the CIF will invest in the following areas:

• Access to healthcare
• Behavioral health
• Food insecurity
• Housing insecurity
• Workforce development for careers in healthcare

Impact awards

• Designed for 5-year initiatives where organizations come together to drive measurable impact and longer-term change in the communities we serve by improving existing systems and innovation
• Emphasize strategic cross-sector and/or intra-sector partnerships between community-based organizations
• Uplift community members of greatest need
• Directly align with CIF areas of focus and meaningfully contribute to CIF goals
• Award amount: $1 million per year, up to 5 years

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CRRP 

Through the competitive Collaborative Regional Research Programme (CRRP), we promote regional research that has potential to improve our understanding of global change and its implications while contributing to a sound scientific basis for policymaking in areas affected by global change. Under this pillar, APN supports collaborative research that contributes to the evolving science-policy arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction and the UN Decade of Ocean Science as well as ongoing and new global change and sustainability research programmes.

Activities of interest under the CRRP Programme

APN promotes regional collaborative research that improves understanding of the physical, biological and human dimensions of change in the Earth system and advances actionable science that informs decision-making. APN accepts proposals that engage at least 3 member/approved countries in the region, and prioritise collaboratively designed, actionable research with non-academic stakeholders. Proposals must address one or more of the following activities:

• Collaborative research on global change and sustainability that particularly addresses GAPS, ANALYSIS, SYNTHESIS and ASSESSMENT work.
• Collaborative research that develops PATHWAYS and MECHANISMS to achieve sustainable development, and develop adaptation strategies.
• Collaborative PLACE-BASED INTEGRATIVE RESEARCH, particularly from developing countries.
• Collaborative research that is CO-DESIGNED to contribute to the Paris Agreeemnt, Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, Post-2020 Global Biodiversity Framework, UN Decade of Ocean Science (2021-2030), and the accumulation of scientific knowledge at IPCC, IPBES, etc.

The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.

The George H. and Charlotte B. Cressy Memorial Scholarship supports adult learners in Maine aiming for post-secondary education. Established in 2021, it assists residents of Greater Portland in overcoming financial barriers to educational opportunities at accredited institutions, including colleges and trade schools. Eligibility includes being a Maine resident and meeting one of several criteria for nontraditional students, such as age or financial independence. This scholarship empowers individuals to pursue personal and professional growth through education.

The Mattina R. Proctor Foundation Grant focuses on healthcare initiatives in Maine and Massachusetts, supporting projects that address public health and medical research. With grants typically ranging from $2,500 to $50,000, the foundation seeks to impact underserved populations through diabetes research, dental care, and preventative healthcare measures. Eligible applicants must be 501(c)(3) organizations demonstrating a specific need, emphasizing the foundation's commitment to meaningful, community-focused giving.

The CIF Capacity Builder Awards by Endeavor Health focus on enhancing community health through strategic investments. With over $38.5 million allocated to local partnerships, these awards aim to address critical areas like healthcare access, food insecurity, and workforce development. Designed for nonprofit organizations, the awards range from $100,000 to $500,000 annually for 1-2 years, fostering long-term community impact and advancing health equity in the service areas.

The Maine Department of Education is inviting proposals for the 21st Century Community Learning Center (21st CCLC) Grants, aimed at funding afterschool and summer programs for students from Pre-K to grade 12. This initiative supports partnerships that enhance academic performance and provide essential enrichment opportunities for students in economically disadvantaged areas, while also offering safe environments for families during non-school hours.

The Therapeutic Giving program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatment and advance health equity, particularly in immunology. Eligible nonprofit organizations can apply for support aimed at improving health outcomes through innovative programs. The initiative prioritizes measurable impacts over fundraising activities, emphasizing the importance of addressing healthcare disparities and promoting disease awareness efforts for diseases like rheumatoid arthritis and psoriasis.

The Black, Indigenous, and People of Color Fund Grant, provided by the Maine Community Foundation, supports organizations led by and serving Black, Indigenous, and other people of color. The grant aims to promote equity in Maine through leadership investment, policy change, and combating race-based discrimination. Eligible applicants include nonprofits, municipalities, and public agencies in Maine, with a focus on programming that engages BIPOC communities. Grants offer up to $10,000 per year for various operational needs.

The Keystone Grant Program, funded by the Elmina B. Sewall Foundation, aims to empower grassroots and community-led initiatives focused on environmental and racial justice in Maine. With available funding of up to $1.5 million, the program supports organizations demonstrating a commitment to advocacy and civic engagement. Applicants must be eligible to receive tax-deductible donations and can include diverse groups, particularly those led by marginalized communities, to foster a sustainable and equitable future.

The Pinetop Assistance League (PAL) Grant provides crucial financial support to elderly blues musicians, ensuring their well-being during emergencies. This grant, part of the Pinetop Perkins Foundation's mission, offers assistance for medical expenses, home care, and essential living costs. Eligible applicants must be professional artists aged 50 or older with a household income below $35,000. By addressing these needs, PAL plays a vital role in preserving the legacy and care of blues musicians.