Best Operating Grants for Nonprofits in Maine

The Level 1 Housing Opportunity Grants, provided by the National Association of Realtors, aim to enhance education on housing affordability for REALTORS® and the community. Grants of up to $3,000 support various initiatives, including forums, speakers, and stakeholder meetings. This initiative encourages collaboration and knowledge sharing to address pressing housing issues and promote affordability in communities. Eligible associations can receive one grant annually, with reimbursement requests due by December 19, 2025.

This funding opportunity announcement aims to enhance health interventions for Native American populations. It supports research to develop, adapt, and test culturally informed health promotion and disease prevention strategies. The initiative addresses significant health disparities faced by these communities, emphasizing sustainable and adaptable solutions. Researchers are encouraged to build on community strengths and resilience, focusing on effective dissemination and integration of interventions. The program welcomes applications targeting diverse Native American groups, including Alaska Natives and Native Hawaiians.

The Level 3 Housing Opportunity Grants, offered by the National Association of Realtors, support innovative projects aimed at enhancing housing opportunities. These grants are designed for initiatives that involve collaboration with non-REALTOR® partners and require significant REALTOR® involvement. Eligible projects should demonstrate potential for community impact and cannot include activities previously funded by Housing Opportunity grants. This initiative aims to foster growth and diversity within communities.

The ROSS Rapid Response Program (RRP) by the U.S. Department of Housing and Urban Development (HUD) provides expedited funding to assist communities in addressing urgent social needs. This program offers one-time cost-reimbursable grants for service coordination and direct services, especially in response to emergencies like natural disasters or public health crises. By streamlining the application process, the RRP empowers local leaders to efficiently support residents in HUD-assisted housing, promoting self-sufficiency and resilience.

Drs. Keith and Monica Taylor's Family Scholarship, established in 2021, aims to support qualified African American students facing financial hardships in their pursuit of higher education. This scholarship fund prioritizes those who demonstrate a need for assistance and encourages applicants who have overcome challenges. The Community Foundation of the Lowcountry manages this initiative, ensuring that deserving students receive the financial support necessary to achieve their educational goals.

The Book Buddies Program, initiated by The Molina Foundation, aims to combat the lack of access to books in low-income communities. By distributing new, free books to eligible schools and agencies, the program fosters literacy and learning among children. With over 4 million books distributed, it helps create word-rich environments essential for educational success. This initiative supports families in building home libraries and enhances learning spaces, ensuring children have the resources they need to thrive.

This RFP invites proposals that explore the role of maintenance therapy in HER2+ metastatic breast cancer. It aims to enhance understanding of treatment optimization, emphasizing patient quality of life and individualized treatment strategies. Eligible applicants include organizations from the U.S. and select European countries. The focus is on educational projects that improve awareness among healthcare professionals, with a range of formats accepted, including live sessions and online content. Clinical research projects are excluded.

The Nicholas B. Ottaway Foundation's Community Impact Fund Grants aim to enhance community well-being by supporting 501(c)(3) organizations focused on underrepresented populations. Grants range from $3,000 to $20,000 and are intended for projects in areas like disaster relief and sexual health. First-time applicants must submit a letter of intent before applying. The foundation prioritizes projects in regions where its members live and work, ensuring local engagement and impact.

The Peter S. Slomianyj Scholarship Fund offers financial assistance to Subway employees and their children who meet specific eligibility criteria, including a minimum of 500 work hours over the past year and a GPA of 2.0 in high school or 2.5 in college. Applications for this scholarship will be open from December 16, 2025, to March 3, 2026. It is part of a broader initiative by the North Carolina Community Foundation to support students pursuing education at various institutions.

This funding opportunity supports research aimed at improving health among Native American populations by developing, adapting, and testing interventions. It addresses significant health disparities and seeks culturally informed solutions. The initiative encourages research that informs intervention strategies tailored to community needs, focusing on sustainability and scalability. The program is vital for enhancing health equity and resilience in Native American communities, ultimately aiming to reduce morbidity and mortality through effective health interventions.

The Degree Pathway Scholarships, offered by the Nevada Women’s Fund, empower women in northern Nevada by supporting their pursuit of academic degrees such as associate's, bachelor's, master's, and doctorate programs. These scholarships aim to strengthen communities and promote self-sufficiency through education. Applicants must be enrolled full-time in accredited institutions and meet specific eligibility criteria, including a minimum GPA of 3.0. Announcements for scholarship awards take place each April, fostering women's educational advancement.

Who We Are

Nevada Women’s Fund is a dedicated nonprofit organization committed to empowering women and strengthening communities across Nevada. Since our founding, we have worked to identify and fund critical initiatives that support women’s education, career development, and personal growth. Through scholarships, grants, and collaborative programs, we aim to break down barriers and create opportunities that foster self-sufficiency and achievement. Our mission is driven by a vision of a Nevada where women can thrive, lead, and make lasting contributions to their families, workplaces, and communities.

"The best way to empower women is to educate them.” ~ Michelle Obama

Scholarship History

Nevada Women's Fund scholarship program was established to empower women in Northern Nevada by supporting their educational pursuits. Since its inception, the program has awarded millions of dollars in scholarships to women across the region, helping them achieve their academic and career goals. Over the years, the program has expanded to include support for students in a variety of fields, with a focus on fostering economic self-sufficiency and professional advancement. Through this commitment, Nevada Women’s Fund continues to invest in the potential of women to drive positive change in their communities.

Workforce Ready Scholarships

These scholarships support individuals pursuing education and training pathways outside of a traditional academic degree program, such as:

• Certificate Programs
• Trade or Vocational Training
• Continuing Education or Professional Development
• Licensing

The Cushman Scholarship Fund, established by the Maine Community Foundation in 1983, offers renewable scholarships to residents of Hancock County pursuing post-secondary education in medical or Christian education fields. This initiative aims to support local students in their educational endeavors while fostering community growth through strategic giving and leadership. By providing personalized service and understanding local issues, the Maine Community Foundation continues to enhance educational opportunities for those in need.

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.

The Central Presbyterian Church - Raisner Family Scholarship Fund

The Central Presbyterian Church-Raisner Family Scholarship Fund assists deserving Stark County students who are active in the church or who are children or dependents of an active member of Central Presbyterian Church who are pursuing first-year post-secondary education. Applicants must have a minimum GPA of 2.5 and demonstrate financial need.

Amount:

• Varies. Minimum $500.

Renewable:

• No

The Bausch Foundation, established by Bausch Health Companies Inc., supports global charitable initiatives focused on disease prevention, improving patient outcomes, and education related to its core businesses. The Foundation also aids disaster recovery efforts and assists underserved communities. Applications for funding are accepted continuously, with quarterly reviews, ensuring timely support for impactful projects. All submissions must be unsolicited, and decisions by the Advisory Committee are final, fostering a transparent giving process.

The Rooted Pathways Program, initiated by First Peoples Fund, offers essential support to Native-led arts organizations, fostering their growth and stability. This funding empowers these organizations to thrive in their missions, providing unrestricted operating support and participation in a Learning Cohort. Eligible applicants include Native nonprofits and collectives with budgets under $500,000, and the program aims to uplift artists from U.S. federally recognized tribes. This initiative is part of the Wallace Foundation's broader commitment to enhancing well-being in the arts.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Amyloidosis

Help with healthcare costs for amyloidosis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Amyloidosis is characterized by a build-up in amyloid protein in specific organs or throughout the body. It is a rare disease that affects multiple systems. Subtypes include hereditary amyloidosis, light chain amyloidosis (AL amyloidosis), and amyloid A (AA) amyloidosis (secondary amyloidosis).

The National Human Genome Research Institute (NHGRI) is launching a Notice of Funding Opportunity (NOFO) aimed at enhancing genomic research through the development and distribution of high-value resources. This initiative encourages collaborative efforts in genomic resource development and the integration of data science in clinical applications. While applications are not currently being accepted, prospective applicants are urged to prepare meaningful collaborations and projects ahead of the formal solicitation.

About Us

Children’s Cancer Research Fund is a national nonprofit dedicated to ending childhood cancer. Our main focus is to support the research of bright scientists across the country whose ideas can make the greatest impact for children fighting cancer. We also fund resources and programs that help kids and families as they navigate the difficult experience of cancer treatment and survivorship.

Since 1981, we’ve contributed over $235 million to research, support programs for children and families, and awareness and education outreach. In 2024, over 81 percent of funds raised went directly to these program services areas.

Children’s Cancer Research Fund (CCRF) is a national nonprofit committed to finding safer, more effective therapies for kids battling cancer. Thanks to donors and partners around the country, we have contributed over $235 million to research, education and awareness, and quality-of-life programs for childhood cancer families. We believe kids deserve safer, less toxic treatments, and we’re committed to funding groundbreaking research and services that enhance healing and care.

In 2026, Children’s Cancer Research Fund will focus our research funding efforts on three main areas:

• Hard-to-Treat Cancers
• Survivorship
• Health Disparities

Accelerating Hope: Clinical Trials for Hard-to-Treat Cancers Award

This funding opportunity is limited to support for clinical trials focused on hard-to-treat cancers, prioritizing Phase 0 – Phase 2 studies. Learn more about eligibility criteria and other key details below.

The LAMPS Bob Judd Memorial Scholarship Fund, established in 2021 by the Maine Community Foundation, honors the legacy of Robert L. Judd, a cherished member of Lubec. This annual $1,000 scholarship supports Washington County residents pursuing undergraduate or graduate degrees in music, continuing Bob's tradition of generosity towards students and local musicians. The fund exemplifies community support and encourages the next generation of musical talent.

The Innovation Grants to Nurture Initial Translational Efforts (IGNITE) support the development of assays and screening processes to identify potential therapeutic agents for neurological disorders and non-opioid analgesics. Sponsored by the NIH, this initiative seeks to foster collaborations and projects that utilize innovative methodologies. Although applications are not currently being solicited, interested parties are encouraged to prepare meaningful proposals that align with the goals of the NIH Helping to End Addiction Long Term initiative.

The RFA-FD-23-001 funding opportunity aims to support clinical trials for orphan products targeting rare diseases. It focuses on evaluating the efficacy and safety of treatments to address unmet medical needs. By promoting innovative and collaborative trial designs, the FDA seeks to enhance the approval rates of effective therapies for rare conditions, ultimately benefiting patients and advancing drug development in this critical area.

The RAK Education Foundation Scholarship provides financial assistance to residents of Camden, Chowan, Gates, Pasquotank, or Perquimans Counties who have earned a high school diploma or GED. This scholarship supports students pursuing degrees or certificates in Career and Technical Education fields such as trade education, computer science, business, health science, and more. Applications open on December 16, 2025, and close on March 3, 2026, encouraging eligible students to apply.

The New York Life Foundation Grief Reach Grants aim to enhance the capacity of nonprofit organizations serving grieving children. This program, offered in partnership with the National Alliance for Children's Grief, provides $15,000 grants over one year to support internal improvements like organizational development and strategic collaborations. The initiative focuses on strengthening infrastructure and sustainability, ensuring that children have the resources they need to cope with loss effectively.

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Pink Gravel Fund

The purpose of the Pink Gravel Fund is to provide funds to qualified individuals to cover expenses related to the treatment and recovery of breast cancer. 

The Beim Foundation's Regional Grant Program invites proposals from nonprofit organizations serving under-resourced communities in the U.S. for environmental education projects by 2025. The foundation prioritizes initiatives that address ethnic and racial inequality, heal community trauma, and provide culturally competent services. Grant amounts range from $5,000 to $15,000, supporting direct services to participants rather than staff training or curriculum development. Applications are limited to specific geographical areas.

The Marie Darlin Prize, administered by the Juneau-Douglas City Museum and overseen by the Juneau Community Foundation, honors exceptional artistic and scholarly works that reflect Southeast Alaska's cultural heritage. Awarded annually, the prize of $5,000 recognizes individuals or collaborations committed to the region's social and cultural history, community advocacy, and Indigenous identity. Eligible applicants include writers, visual artists, and performers who have produced significant works within the last five years.