Best Large Grants for Nonprofit Organizations in Nebraska

The St. Baldrick’s Foundation Research Grant Award supports innovative research aimed at curing childhood cancers. With funding of $100,000 per year for two years, this grant is designed for hypothesis-driven projects that can be laboratory, clinical, or epidemiological in nature. Established through community-driven fundraising events, the foundation empowers volunteers and donors to make a significant impact in the fight against cancer, ensuring a brighter future for young survivors.

The CareQuest Institute for Oral Health® is inviting proposals for school-based and school-linked initiatives aimed at improving oral health access for high-risk children. This grant opportunity seeks to address systemic barriers to oral health through innovative programs that engage schools and communities. Ideal projects may include workforce development, community engagement strategies, policy advocacy, and the use of technology. Proposals should focus on creating equitable oral health solutions that enhance both health and academic success for children and their families.

The Kidney Precision Medicine Project (KPMP), funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), aims to enhance research on Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). Launched in 2017, this initiative focuses on ethical collection and analysis of human kidney tissue to uncover new molecular pathways. With expanded participant recruitment efforts beginning in 2022, the KPMP seeks to advance our understanding of kidney-related health issues.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is extending the Kidney Precision Medicine Project (KPMP) for five years to enhance participant recruitment and tissue interrogation. This initiative aims to discover novel molecular pathways associated with Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). The renewed funding will support robust longitudinal follow-ups for existing enrollees and facilitate the enrollment of new participants, ensuring comprehensive data analysis and collaboration within the research community.

The Kidney Precision Medicine Project Central Hub, funded by the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), aims to enhance our understanding of Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). This initiative, which began in FY2017, focuses on ethically collecting and analyzing kidney biopsy tissues to uncover molecular pathways. The project was expanded in FY2022 to improve participant recruitment and tissue analysis, driving forward research in kidney health.

The AHA Quest for Quality Prize recognizes hospitals and health systems that demonstrate exceptional leadership in improving care quality and advancing health. Applicants should showcase innovative models of care and effective partnerships with community organizations. One winner and two finalists will be honored at the 2026 AHA Leadership Summit in Denver. This award aims to inspire hospitals to commit to patient-centered care and address healthcare disparities, ultimately enhancing community health outcomes.

The Frederic C. Collin Trust Grant supports 501(c)(3) organizations in promoting polo and tennis, especially among youth. Established under Frederic C. Collin's will, it offers grants ranging from $2,000 to $3,800, with an annual total giving of approximately $9,000. Applications are accepted year-round for consideration during the annual grant meeting. This initiative aims to enhance participation in these sports, fostering talent and interest among young players.

The CFF/NIH R01-Unfunded Award, offered by the Cystic Fibrosis Foundation, supports exceptional CF-related research projects that have been submitted to NIH but lack funding. This program aims to bridge the gap for meritorious projects, providing up to $125,000 per year for two years. By facilitating research in cystic fibrosis, the foundation helps ensure that innovative ideas can continue to progress toward improving care and outcomes for individuals affected by this disease.

The CF Foundation/NIH K-Unfunded Award aims to support exceptional research projects in cystic fibrosis (CF) that have been approved by the NIH but lack funding. This award provides temporary financial assistance of up to $80,000 per year for two years to ensure that promising CF research continues without interruption. The initiative focuses on fostering a new generation of researchers dedicated to advancing CF studies while encouraging the NIH to provide long-term support.

Idaho Community Foundation

The Idaho Community Foundation distributes millions annually in grants and scholarships across the state. These awards are made possible by individuals, families, businesses, affiliates, giving circles, and everyday Idahoans who care for their community.Robert C. Weaver Memorial Scholarship FundEstablished by Neola Weaver in memory of her late husband, residents or former residents of Buhl are eligible for scholarship support as either traditional or nontraditional students. For part-time or full-time traditional or nontraditional students pursuing post high school vocational or academic training. 

The Cystic Fibrosis Foundation's Student Traineeship Award supports students in engaging with cystic fibrosis research through hands-on projects. With a maximum funding of $4,000 for one year, the program aims to inspire students to pursue careers in CF research or care. Eligible applicants must be enrolled in a degree program and collaborate with a faculty mentor on a relevant project. This initiative also emphasizes the importance of maintaining interest in CF-related research among new generations.

The Cystic Fibrosis Foundation offers a Travel Award Supplement aimed at supporting Ph.D. students, postdoctoral fellows, and junior faculty. This funding of up to $3,000 enables trainees to participate in off-site workshops or training programs to enhance their research skills. Eligible applicants must be active researchers in CF projects, with a minimum of one year of experience. The program excludes conference attendance and for-profit entities, ensuring focused support for advancing cystic fibrosis research.

The Harry Shwachman Clinical Investigator Award, offered by the Cystic Fibrosis Foundation, supports clinically trained physicians transitioning to independent researchers in cystic fibrosis. It provides up to $133,000 per year for three years to facilitate research tailored to individual interests. The funding covers personnel costs and supplies, promoting a strong mentorship during this critical stage of their academic careers.

The Path to a Cure (PTAC) - Postdoc-to-Faculty Transition Award by the Cystic Fibrosis Foundation supports postdoctoral fellows in advancing their research careers in cystic fibrosis. This program offers up to five years of funding, including 3 years for research training and 2 years for transitioning to an independent faculty position, with a maximum support of $110,000 per year. It aims to foster innovative research that develops new therapies for cystic fibrosis.

The Rapid Outcomes from Agricultural Research (ROAR) Grant Program, managed by the Foundation for Food and Agriculture Research (FFAR), provides urgent funding for research addressing unexpected threats to the food supply. This program supports diverse projects related to pest and pathogen outbreaks, facilitating quicker responses than traditional funding avenues. With grants up to $150,000, ROAR aims to enhance agricultural resilience by fostering collaborations among researchers, institutions, and organizations to combat emerging challenges in the food and agriculture sector.

The Cystic Fibrosis Foundation offers the Path to a Cure (PTAC) Postdoctoral Research Fellowship Award to support innovative research training in cystic fibrosis (CF). Aimed at enhancing scientific knowledge and facilitating the transition to independent careers, this program funds projects targeting the development of new therapies for CFTR variants. Awards can reach up to $75,000 in the first year and $76,000 in the second year, fostering foundational research that could lead to breakthroughs in CF treatment.

The FY26 Reconstructive Transplant Research Program (RTRP) Investigator-Initiated Research Award supports innovative studies aimed at enhancing reconstructive transplant research and patient care. It emphasizes projects with military relevance, focusing on all research phases from basic to clinical. Essential components include rigorous study design, preliminary data, and the potential for significant short- and long-term impacts on patients and the reconstructive transplant field.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

The T.E.A.L. Research Grant supports innovative ovarian cancer research initiatives aligned with the mission of the Tell Every Amazing Lady About Ovarian Cancer Foundation. Designed for researchers affiliated with 501(c)3 not-for-profit institutions in the U.S., the grant aims to enhance women's health awareness and education regarding ovarian cancer. While the application period for 2025 is currently closed, interested parties should anticipate further updates in spring 2026.

The Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42) program invites small business concerns to develop innovative technologies aimed at enhancing minority health and addressing health disparities. This initiative emphasizes the creation of effective, affordable, and culturally acceptable solutions for NIH-defined populations. Key deadlines for applications span from June 2024 to December 2026, with optional Letters of Intent encouraged 30 days prior to submission.

The Innovations for Healthy Living program invites eligible U.S. small businesses to apply for SBIR grants aimed at improving minority health and eliminating health disparities. The initiative encourages innovative proposals for effective, affordable, and culturally acceptable solutions. Key deadlines for applications span from June 2024 to December 2026, with optional Letters of Intent recommended 30 days prior to submission. This funding opportunity supports projects that address health challenges faced by underserved populations.

The Karl A. Bickel and Madira Bickel Journalistic Scholarship Fund Grant supports journalism students at accredited colleges and universities. Established under Karl A. Bickel's Last Will and Testament, it awards approximately $40,000 annually. Eligible organizations must have journalism programs and qualify as 501(c)(3) exempt entities. While there are no geographical restrictions, preference is given to institutions in Florida. The fund is administered by Wells Fargo Bank, ensuring that deserving students receive necessary financial support.

The Catholic School Leadership Development Grant Program aims to cultivate and retain promising leaders within the Catholic school system. In partnership with Loyola Marymount University, this initiative offers a graduate-level online Certificate in Catholic School Administration, covering 80% of tuition costs and providing funding for essential travel. The one-year program focuses on mission effectiveness, operational management, and instructional leadership, requiring participants to serve two years in their diocese post-completion, thereby enhancing local educational leadership.

The Anna B. Glauser Trust Grants provide financial support to organizations aiding physically handicapped individuals, particularly blind residents in Delaware County, PA. Established in memory of Willis K. Glauser, the trust awards 1-2 grants annually, ranging from $2,500 to $5,000. Eligible organizations must be 501(c)(3) certified, while funding for salaries is typically excluded. This initiative reflects Anna Glauser's lifelong commitment to assisting the visually impaired community.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

Joseph and Lorraine Finley Scholarship

Purpose of Scholarship

To provide financial support to high school seniors who are residents of the Wayne County town of Walworth and continuing their education at any accredited two-year, four-year, or technical school.

Number and Size of Awards

Four awards of $7,000 each; paid as $1,750 per year for up to four consecutive years of undergraduate study. Award paid in the Fall and divided equally between the Fall and Spring semesters.

Donor Information

This scholarship was established by a couple who believed in education and in helping their community.

The William C. Risser Charitable Trust Grants support mental health research, particularly in Schizophrenia. This private foundation assists 501(c)(3) nonprofit organizations across the U.S. with grants typically ranging from $25,000 to $55,000. Administered by Wells Fargo, the Trust awards 1-2 grants annually, focusing on program support for scientific and educational research. Eligible organizations must meet IRS exemption requirements.

Rapid Cancer Grants

Fast Funding for Home Cancer Care Research

We fund healthcare researchers to rapidly explore the feasibility of home infusion as a solution to the ongoing challenges of capacity shortage, site of care management, and financial toxicity in cancer care.

Traditional funding pathways for new care models are too slow to impact patients, so we’ve streamlined the process. By providing funding approvals within 14 days, we enable healthcare teams to quickly launch and evaluate home-based cancer care programs that improve access and affordability.  

What can a Rapid Cancer Grant be used for?

Projects must comprise of research investigating the feasibility, safety, or economic benefit of cancer care at home and must include delivering care to patients via an IRB approved study. IRB approval may be obtained after grant approval. Projects may include assessing suitability of home infusion, enabling access to lab draws at home, or remote care co-ordination to reduce time toxicity for patients.

If you’re a healthcare worker at an oncology practice, hospital or academic institution in the United States and are interested in continuing or launching a new home cancer care initiative, we invite you to apply for a Rapid Cancer Grant.