Best Large Grants for Nonprofit Organizations in Nevada

National Main Street Center Inc.

Main Street America (MSA) leads an inclusive, impact-driven movement dedicated to reenergizing and strengthening older and historic downtowns and neighborhood commercial districts through place-based economic development and community preservation. We work in collaboration with thousands of local partners and grassroots leaders across the nation who share our commitment to advancing shared prosperity, creating resilient economies, and improving quality of life.

Main Street America was founded in 1980 as the National Main Street Center®, a program of the National Trust for Historic Preservation. Over the past 40 years the MSA network has helped to generate over $115.27 billion in local reinvestment, rehab 345,801 buildings, create 815,894 new jobs, and start 181,647 new businesses in over 2,000 communities. 

Great American Main Street Awards

Main Street America celebrates communities whose successes serve as a model for comprehensive, preservation-based revitalization efforts in their historic downtowns and commercial corridor districts with the Great American Main Street Awards (GAMSA).

Winners represent the diversity of communities in the Main Street America network — small towns, mid-sized communities, and urban commercial districts from every region in the country — and demonstrate the power of the Main Street Approach™. Since the inception of the Great American Main Street Awards in 1995, 118 Main Street programs have been honored.

Selection Criteria: Semifinalists and winners are selected from a nationwide pool of applicants by a jury of Main Street professionals and leaders in the fields of community and economic development and historic preservation. Criteria for winning GAMSA include: strength of the Main Street program in spurring community transformation, commitment to historic preservation, innovative programming, implementation of cross-sector partnerships, community outreach and stakeholder engagement, and ensuring their downtown districts are for everyone. 

Accolades & Ceremony: Semifinalists are promoted through Main Street America’s digital channels and receive media relations support. Winners also receive a short documentary film, a plaque, communications and media relations support, prominent placement on the Main Street America website for two years, and recognition at the 2027 Main Street Now Conference in Detroit, Michigan.

The Sharing Language Diversity Fellowship supports Ph.D. students engaged in Indigenous language documentation and data archiving. Funded by the Endangered Language Fund, it encourages sustainable public sharing of linguistic materials, aiming for equitable access to research. With grants up to $30,000, recipients must publicly archive documentation materials within three years, ensuring compliance with community wishes and best practices. This initiative fosters a culture of Open Access in linguistics, benefiting both scholars and Indigenous communities.

The NIH invites applications to study environmental factors affecting animal research rigor and reproducibility. This initiative encourages core facilities and investigators to enhance scientific understanding through modern equipment that measures various biological and behavioral variables. Proposed research must align with NIH's mission, addressing critical processes impacting multiple organ systems. The goal is to improve the reliability of animal studies by systematically evaluating extrinsic influences in biological contexts.

Linda Norton Good Neighbor Scholarship

This scholarship is designed to support exceptional students within the Poudre School District who aspire to pursue degrees in finance, economics, business, or real estate. It embodies Linda Norton’s legacy of community service, advocacy, and significant contributions to the field while providing opportunities for the next generation of students in these related disciplines.

Scholarship amount:

• $1,500

Number of awards:

• 1

Scholarship awards are one-time awards. The amount awarded to a selected recipient may be used for the cost of attendance. All scholarships will be paid directly to the recipient’s school and must be used for the upcoming academic year. Award disbursement is contingent upon the outside scholarship policies of a recipient’s college or university.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

The AWWA Scholarship Program, specifically the Neptune Technology Group Scholarship, offers a $5,000 award to undergraduate students pursuing degrees in mechanical, electrical, computer, or software engineering. This initiative, supported by the American Water Works Association, highlights the importance of investing in the future workforce of the water industry, fostering education and innovation among aspiring professionals.

The Lenora Jane Perdue Scholarship, offered by the North East Community Foundation, supports graduating seniors from Westfield Academy, Ripley Central School, and North East High School pursuing a degree in education. Applicants must maintain a GPA of 3.0 or higher. This scholarship aims to encourage and assist students dedicated to a career in teaching, fostering the next generation of educators in their community.

The Charles Lathrop Parsons Award, presented by the American Chemical Society, honors exceptional public service by ACS members. This prestigious award includes a $5,000 monetary prize and a certificate. Up to $2,500 can be reimbursed for travel expenses related to the award ceremony. It is awarded every two years, although the interval may be shortened at the discretion of the ACS Board for deserving nominees. All eligible members are encouraged to apply.

The ASTRO-AAPM Physics Resident/Post-Doctoral Fellow Seed Grant supports early-career scientists in radiation oncology physics research. Jointly funded by AAPM and ASTRO, this grant aims to foster innovation in the field, with up to two awards of $50,000 each available. Eligible applicants include medical physics residents and post-doctoral fellows who are active members of ASTRO and AAPM. This initiative strives to enhance the next generation of researchers, ensuring a commitment to advancing radiation oncology.

The Creation & Development Fund, administered by the National Performance Network, supports the creation and mobility of artistic works that promote racial and cultural justice. It fosters collaboration between artists and communities through financial support, enabling artists to develop meaningful relationships and present their work. The fund emphasizes equity, access, and the importance of public engagement, ensuring that diverse voices are represented while addressing systemic injustices in the arts.

About Us

Our Mission

The Marfan Foundation drives research, education and support – and builds community – to improve outcomes, save lives and empower all people to thrive who are living with Marfan, Loeys-Dietz, Vascular Ehlers-Danlos syndromes, and related genetic aortic and vascular conditions.

Our Vision

Quality of life, longevity, and cures for all people with genetic aortic and vascular conditions.

Career Development Award

The Career Development Award will support two-year $100,000 grants ($50,000 per year) in basic, translational, or clinical research studying any discipline involved in Marfan syndrome, Loeys-Dietz syndrome, Vascular Ehlers-Danlos syndrome, and other related conditions. This grant program is designed to support investigators early in their career to derive preliminary data in a key concept area that has high potential to lead to extended funding from NIH, EU, and other large research funding sources.

This grant aims to enhance safety and health in U.S. mining operations through research in automation, robotics, and intelligent systems. It addresses critical issues like emergency communication and self-escape reliability while supporting the development of field-ready solutions. By leveraging advanced technologies, the initiative seeks to improve miner safety and health, reduce hazardous exposures, and foster community engagement. Applicants must be U.S. academic institutions with accredited mining programs, linking project goals to documented health burdens.

The ACS-Hach High School Chemistry Classroom Grant aims to enhance chemistry education by providing funding for innovative teaching ideas. Since its inception in 2008, over 700 teachers have benefited from grants of up to $1,800. Eligible applicants are U.S. high school chemistry educators, and the funding can be used for laboratory supplies, instructional materials, professional development, and student-led field studies, fostering a deeper understanding of chemistry.

Unless noted otherwise in the scholarship description and criteria statement, applicants can attend accredited schools of their choice within the United States.

CFNJ scholarships awards vary. On average, awards range from $500 to $2,500. However, the award could be larger based on the number of qualified applicants and the parameters set by donors who have established the funds. 

James L. and Ruby L. Murray Memorial Scholarship

This scholarship will be awarded to a college-bound, graduating senior from one of the following high schools: Trenton High School, Ewing High School, Cherry Hill High School West, or East Orange High School. Applicants must be pursuing a bachelor’s degree in history, social science, or political science at any college/university of their choice within the United States. Students also must have achieved a cumulative 3.0 GPA or better.

About Us

The Wenner-Gren Foundation is a private operating foundation dedicated to providing leadership in support of anthropology and anthropologists worldwide.

Our Mission

The Wenner-Gren Foundation is committed to playing a leadership role in anthropology. We help anthropologists advance anthropological knowledge, build sustainable careers, and amplify the impact of anthropology within the wider world. We dedicate ourselves to broadening the conversation in anthropology to reflect the full diversity of the field.

Engaged Research Grant

General

This program supports longstanding research partnerships that empower those who have historically been the subjects of anthropological research, rather than researchers themselves. Designed in alliance with individuals who have borne the impact of marginalization, these partnerships bring together scholars and their interlocutors in an effort to expand anthropological knowledge, combat inequality, and help communities flourish. The program supports projects that will make a significant contribution to anthropological conversations through collaboration and engagement.

Anthropological research involves forging ethical relationships. Researchers must acknowledge the contributions of interlocutors and compensate them appropriately for their labor and time. Projects funded by Engaged Research Grants go even further. Not only are interlocutors participants in the research, but they have an active role in determining the problems explored. This grant program targets projects, growing out of a scholar’s established relationship with a community, that show greater potential when undertaken as a partnership, beginning with the formulation of research questions and extending to data gathering, skill sharing, scholarly communication, and public mobilization. Engaged research occurs in a broad range of settings, including communities, courtrooms, government offices, and laboratories. It results in findings that are meaningful and potentially transformative for research participants and others with a stake in the collaboration. Through this program, the Foundation seeks to demonstrate how engagement can foster innovation and further anthropological knowledge.

Award Money

The maximum Engaged Research Grant is $25,000. There is no limit to the duration of the grant, and applicants may request funding to cover distinct research phases (for example, two summers) if this is part of the research design.

The George Family Foundation offers Spirituality & Inner Life Grants to empower organizations that foster mindfulness and personal healing. They seek to support programs that promote respect, empathy, and compassion, aiming to bridge divides and enhance individual well-being. The foundation prioritizes initiatives that align with their mission, particularly those addressing meaningful community needs. They focus on 501(c)(3) organizations primarily in Minnesota and select areas, emphasizing innovative spiritual and inner life endeavors.

The Civic Experiment Grant by the Trust for Civic Life supports innovative, community-driven projects aimed at enhancing civic engagement. It focuses on rural areas, empowering local leaders to tackle challenges collaboratively. Grants up to $25,000 are available for organizations that are non-partisan and primarily serve rural communities, emphasizing inclusivity and sustainable impact. The next nomination period begins in early 2026, following a closed cycle for 2025. This initiative fosters long-term civic infrastructure and community resilience.

The John K. Fairbank Prize in East Asian History, awarded by the American Historical Association, recognizes exceptional scholarly work in the history of East Asia, particularly focusing on books published after 1800. Eligible works must demonstrate high literary merit and can be nominated by authors or publishers. The prize aims to highlight significant contributions to the historical disciplines, with recipients announced in October 2025 and honored at the January 2026 AHA annual meeting in Chicago.

Better World Scholarship Fund

The scholarship encourages women to acquire a degree in a science, technology, engineering, or math (STEM) field. The donor’s bachelor’s degree is in mathematics, followed 15 years later with a master’s degree in business administration. Her degree in mathematics provided opportunities for jobs in software development and application, medical research, technical documentation, organizational education and training, scientific research, and business. Her career was challenging, dynamic, encouraged creativity, never boring, offered schedule flexibility that allowed her to parent her four children, provided career choice independence, and was lucrative. Go STEM Girls!

Award Amount:

• Minimum $1,000

The All of Us Research Program seeks to advance its mission by enabling access to biospecimens stored in the All of Us supported Biobank for researchers to conduct assays to evaluate associations between biomarkers and chronic diseases and add data to the All of Us resource for broad use by researchers. Biomarker analysis includes, but is not limited to, biomarker discovery; biomarker validation; novel disease stratification; and multiomics integration for disease risk, diagnosis, and prognosis, in support of advancing precision medicine. The All of Us Research Program is a historic effort to enroll 1 million participants who share data to accelerate research and medical breakthroughs, and enable individualized prevention, treatment, and care. Researchers use data from the program to learn more about how individual differences in lifestyle, environment, and genetics can influence health and disease.Grant authorities that allow the All of Us Research Program to forecast this opportunity are as follows: 42 USC 241 and 284.

About Spirit of Blue

Our Vision

To become the nation’s leading supplemental provider of law enforcement safety equipment and training across the county.

Our Mission

Spirit of Blue is dedicated to the enhancement of officer safety throughout the law enforcement community by fulfilling unfunded safety equipment and training needs.

Safety Grant Program

Spirit of Blue’s primary initiative is the granting of safety equipment and training to municipal, county and state law enforcement agencies in an effort to protect their sworn personnel. 

Most grants are 100% funded, meaning that no match is required. In the majority of cases, Spirit of Blue conducts the procurement of the goods or services being granted so that the recipient agency isn’t burdened with having to negotiate prices, place orders or track delivery. Rarely, if ever, does Spirit of Blue provide cash awards. Once selected, Spirit of Blue will provide the recipient agency with an official grant award letter outlining everything that is contained in the award. The recipient agency must gain acceptance of the grant, whether on the authority of their agency head or by working with their local governing authority as their policy may dictate. There are no reporting requirements after the award of the grant, but agencies are asked to submit a photo to be used in the announcement of their grant.

Grant Application

The Spirit of Blue Safety Grant Program is designed to award equipment, or in some cases training, that will protect officers serving on duty. You should only request items that you can articulate will have a positive impact on officer safety.

The NSF Geosciences Core Research program funds innovative projects across atmospheric, geospace, earth, and ocean sciences. It encourages proposals that push the boundaries of knowledge in fundamental research, promoting interdisciplinary approaches. This initiative seeks transformative ideas that may not have immediate commercial applications but are crucial for advancing scientific understanding and addressing complex environmental challenges. Researchers are invited to explore various domains or integrate multiple disciplines to enhance our comprehension of the Earth and its systems.

The AOAP Swim Lesson Grant aims to enhance drowning prevention by providing financial support to aquatic facilities for swim lessons and life jackets. With a minimum allocation of $10,000 annually, the program seeks to offer at least 100 free lessons to low-income participants and distribute 500 life jackets each year. It encourages non-profit organizations to apply, ensuring a focus on education and safety in aquatic environments. This grant represents a significant step towards making swimming accessible and safe for all.

The Dairy Health, Efficiency & Resource Dynamics Initiative Grant seeks innovative research proposals to enhance animal health, economic viability, and environmental outcomes in the U.S. dairy industry. A partnership between FFAR, Dairy Management Inc., and Zoetis, this initiative aims to explore the interconnections between dairy health, welfare, economics, and environmental sustainability, addressing critical gaps in understanding the impacts of improved animal health on dairy production.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The Robert B. B. and Josephine N. Moorman Scholarship, established in 2008 by the American Society of Civil Engineers (ASCE), provides financial support for undergraduate students pursuing degrees in civil engineering or related fields. This scholarship honors Robert B.B. Moorman, a dedicated civil engineering professor. Eligible applicants must be enrolled in an ABET-accredited program and maintain good standing with ASCE. This award aims to alleviate tuition costs for deserving students committed to the civil engineering profession.

The Lawrence W. & Francis W. Cox Scholarship, established by Mrs. Wahneta T. Hinrichs in 2008, honors the legacy of her husband and father-in-law. This scholarship is awarded annually to one undergraduate civil engineering student enrolled in an ABET-accredited program. It aims to support students with tuition expenses, furthering their education in civil engineering disciplines, thus contributing to the profession's growth and sustainability.