Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $25,000,000
The National Cancer Institute (NCI) is inviting applications for the Specialized Programs of Research Excellence (SPOREs) in Human Cancers for 2027-2029. This funding opportunity supports innovative translational research aimed at improving prevention, detection, and treatment of organ-specific cancers. Eligible projects may address related cancer types from the same organ system or focus on common biological mechanisms. The program emphasizes research that translates findings into clinical applications, with the goal of achieving a human endpoint during the grant period.
Cancer / Oncology
Limited Competition: Supporting Programs to Advance Research Knowledge in Environmental Health Sciences (SPARK-EHS) (UE5/T32 - Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $20,000
The SPARK-EHS initiative aims to broaden the reach of NIEHS training by launching innovative environmental health programs for predoctoral trainees at institutions without recent NIEHS T32 funding. This initiative focuses on research regarding the impact of the environment on biological systems and seeks to translate findings into practical health solutions. Eligible institutions will receive support for developing and implementing these targeted training programs, fostering advancements in environmental health research.
Environmental Health
Small Instruments and Modern Equipment for Shared-use Biomedical Research Facilities and Resources (S15 Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $25,000 - US $350,000
The Small Instruments and Modern Equipment program invites shared-use biomedical research facilities to apply for funding to purchase small instruments or scientific equipment. These resources, which may include core facilities and biorepositories, aim to enhance operational efficiency and support the use of innovative technologies. Funding is specifically targeted for instruments that produce outputs beyond traditional digital data, excluding highly specialized or building-level infrastructure equipment.
Biomechanics
Biomedical informatics
Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Drug Abuse (NIDA) aims to establish a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics. This Center will educate researchers on product development for SUD therapies and provide technical and financial support for initial experiments. It encourages collaboration and outreach to enhance research efforts in drug addiction. Investigators with relevant expertise are invited to consider applying for future opportunities to develop impactful solutions in SUD pharmacotherapeutics.
Pharmacology
Addiction & Substance Use Disorders
Improving Linkage to Care for People with Opioid Use Disorder (U01)
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $550,000
The CDC's NCIPC is seeking research proposals to tackle implementation challenges in providing linkage to care services for individuals with opioid use disorder (OUD). This initiative encourages partnerships with public health entities and local healthcare champions to create actionable, evidence-based strategies. The goal is to enhance care access and ensure comprehensive overdose prevention services are available in real-world healthcare settings, thereby improving outcomes for those at risk of opioid overdose.
Addiction & Substance Use Disorders
Health Care Access & Delivery
BioLEAP Classroom Grants
National Anti Vivisection Society
Private
American Samoa, Guam +4 more
Up to US $1,000
The BioLEAP Classroom Grants, funded by the National Anti Vivisection Society, support U.S. educators in purchasing humane alternatives to animal dissection. Grants of up to $1,000 are available for innovative learning tools like 3D models and synthetic specimens. This initiative promotes ethical education in anatomy labs, ensuring teachers have access to effective resources while fostering a compassionate approach to learning.
Anatomy
STEM / STEAM Education
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative's funding opportunity aims to support the establishment of facilities at minority-serving and IDeA-eligible institutions for the production and distribution of brain cell type-specific reagents. These reagents will enhance neuroscience research by enabling precise manipulation and access to brain cell types, facilitating advancements in understanding circuit functions in various species. The initiative encourages collaboration among awardees to optimize the use of these essential resources across the neuroscience community.
Neuroscience
NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $8,750,000
The NICHD Resource Program Grants in Bioinformatics aim to support the operation and enhancement of vital bioinformatics databases for research on animal models of embryonic development. These grants promote user training, data curation, and interoperability with NIH resources, ensuring wide dissemination of critical tools and resources to the research community. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the proposal deadline.
Biomedical informatics
Developmental Biology / Embryology
Precision Approaches in Radiation Synthetic Combinations (PAIRS, RP1 Clinical Trial Optional)
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Cancer Institute's PAIRS program aims to explore innovative cancer therapies by leveraging synthetic vulnerabilities that interact with tumor responses to radiation therapy. This initiative supports the development of targeted drug-radiation combinations, focusing on precision medicine to optimize treatment efficacy while minimizing harm to normal tissues. By consolidating prior funding opportunities, PAIRS encourages research that addresses context-dependent vulnerabilities, enhancing therapeutic strategies and aligning with NIH's scientific goals.
Cancer / Oncology
Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) (356887)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Limited Competition: Basic Instrumentation Grant (BIG) Program offers funding to NIH-supported researchers for purchasing specialized instruments or integrated systems, with minimum awards of $25,000 and maximum awards reaching $350,000. Eligibility is restricted to institutions that have not received significant S10 funding in recent years. This program aims to enhance research capabilities by providing access to essential technology, thereby fostering scientific innovation and collaboration within the NIH community.
Biology
Health & Medicine
Medical Technology, Devices, and Equipment
Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) (356886)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Shared Instrumentation Grant (SIG) Program supports NIH-funded investigators in acquiring high-cost, specialized instruments, with a minimum award of $50,000 and a maximum of $750,000. Eligible instruments include light microscopes, mass spectrometers, and DNA sequencers, among others. This program aims to enhance research capabilities by enabling the purchase or upgrade of essential equipment for scientific advancement.
Biology
Health & Medicine
Medical Technology, Devices, and Equipment
Mission Boost Grants (MBG)
American Cancer Society
Association/Society
American Samoa, Guam +4 more
US $100,000 - US $500,000
The Mission Boost Grants (MBG) by the American Cancer Society aim to enhance cancer research by funding projects that translate into human testing. These grants support investigators at all levels, offering resources for innovative clinical projects. The program consists of two funding stages: Stage I focuses on developing clear milestones for new treatments, while Stage II supports patient testing, ultimately contributing to advancements in cancer care and treatment.
Cancer / Oncology
DOJ FY 2026 Bridging Immigration-Related Deficits Experienced Nationwide (“BIDEN”) Program Round 2
Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The DOJ's FY 2026 BIDEN Program aims to address immigration-related challenges by providing funding to eligible state and local governments. This initiative focuses on enhancing law enforcement's capacity to apprehend criminal aliens, investigate gang activities, and manage court operations related to crimes committed by aliens. By supporting these critical efforts, the program aims to improve public safety and uphold the rule of law in communities across the nation.
Domestic / Homeland Security
Crime & Justice
Health Promotion and Disease Prevention Research Centers: 2027 Special Interest Project Supplements (SIPS)
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The Health Promotion and Disease Prevention Research Centers are offering supplemental funding for Special Interest Projects (SIPs) aimed at enhancing public health practices. These projects will focus on innovative health promotion and disease prevention strategies to mitigate leading health risks in the U.S. The initiative supports ten specific SIPs, including studies on cancer care, alcohol use reduction, and emergency preparedness, thereby fostering research that translates into real-world health improvements.
Cancer / Oncology
Improving Protection against Influenza and Other Respiratory Pathogens: the US Flu VE Network
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $1,350,000 - US $3,550,000
The US Flu Vaccine Effectiveness (VE) Network aims to enhance the effectiveness of vaccines against influenza and other respiratory pathogens, which are significant contributors to morbidity and mortality. This funding opportunity invites proposals for surveillance studies, including annual VE assessments, acute respiratory illness tracking, household transmission research, and immunogenicity studies. Applicants can apply for either Component A or B, with the option to include additional components based on their primary selection.
Respiratory Diseases & Systems
DoW Spinal Cord Injury, Investigator-Initiated Research Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $960,000
The FY26 Spinal Cord Injury Research Program (SCIRP) Investigator-Initiated Research Award (IIRA) supports innovative research aimed at enhancing patient care and quality of life for individuals with spinal cord injuries. This award encourages collaboration, allowing an Early-Career Partnership Option for two Principal Investigators, where one must be an early-career investigator. Focused on impactful research from basic to translational science, this opportunity is crucial for advancing SCI knowledge and interventions.
Spinal Cord Injuries
DoW Spinal Cord Injury, Clinical Trial Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $4,960,000
The FY26 Spinal Cord Injury Research Program Clinical Trial Award supports innovative clinical trials aimed at significantly improving spinal cord injury treatment. This funding opportunity encourages collaboration by allowing two Principal Investigators, including an early-career investigator, to drive the research forward. Applicants must partner with at least two SCI community members, ensuring that the project is informed by lived experiences and community needs throughout its development and implementation.
Spinal Cord Injuries
DoW Spinal Cord Injury, Clinical Translation Research Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $2,000,000 - US $2,100,000
The FY26 Spinal Cord Injury Research Program Clinical Translation Research Award funds innovative clinical research aimed at bridging the gap to larger clinical trials. It focuses on accelerating the application of new techniques and improving patient outcomes through effective diagnosis and rehabilitation strategies. Key features include an Early-Career Partnership Option for principal investigators and a requirement for community partner involvement, ensuring collaborative research that meets real-world needs.
Spinal Cord Injuries
DoW Spinal Cord Injury, Translational Research Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,160,000
The DoW Spinal Cord Injury Translational Research Award supports innovative research to transform promising spinal cord injury findings into clinical applications. It features an Early-Career Partnership Option, requiring at least one early-career principal investigator. Collaborations with SCI community partners are essential for providing guidance throughout the project. This funding opportunity aims to enhance the effectiveness of spinal cord injury interventions and improve patient outcomes.
Spinal Cord Injuries
David H. Smith Conservation Research Fellowship
Society for Conservation Biology
Association/Society
American Samoa, Guam +4 more
US $142,100
The David H. Smith Conservation Research Fellowship aims to enhance the skills of early-career conservation scientists through two years of applied research and mentorship. It supports global scientists at U.S. institutions, focusing on pressing conservation issues, and encourages collaboration with practitioners. The fellowship emphasizes cutting-edge research, leadership development, and practical applications in conservation biology, making it an excellent opportunity for those looking to bridge science and policy.
Environmental Conservation
NIOSH Centers of Excellence for Total Worker Health® (U19) (363369)
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $1,400,000
The NIOSH Centers of Excellence for Total Worker Health® (U19) aims to enhance worker well-being by funding research and translation activities that address harmful exposures and improve working conditions. Priority areas include high-risk occupations, young workers, and chronic diseases. The initiative emphasizes strong project coordination, scientific rigor, and economic evaluations. Projects must utilize the NIOSH Worker Well-Being Questionnaire and share findings with the HERO Clearinghouse, fostering innovative solutions for employers and workers.
Occupational Health & Safety
Workers’ Rights
Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $5,000,000
The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.
Environmental Health
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) (353462)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Mentored Patient-Oriented Research Career Development Award (K23) is designed to support the career development of individuals with clinical doctoral degrees committed to patient-oriented research. Key deadlines for standard applications include June 12, October 12, and February 12 from 2024 to 2027. Renewal and AIDS-related grant applications also have specific deadlines. This initiative aims to enhance research focused on improving patient care.
Biology
Health & Medicine
Medical Education & Professional Training
Fiscal Year 2027 Defense University Research Instrumentation Program (DURIP)
US DOD: Dept. of the Air Force, Materiel Command
Federal Government
American Samoa, Guam +4 more
US $50,000 - US $3,000,000
The Fiscal Year 2027 Defense University Research Instrumentation Program (DURIP) by the Department of Defense aims to enhance research capabilities at U.S. higher education institutions. It provides funding for the acquisition of essential research equipment to support education in fields critical to national defense. This initiative specifically excludes for-profit organizations, ensuring that the resources are directed towards accredited educational institutions committed to advancing scientific knowledge and engineering expertise.
International Security
Sheep Production and Marketing Grant Program FY 2026
USDA: Agricultural Marketing Service (AMS)
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $2,400,000
The Sheep Production and Marketing Grant Program (SPMGP) for FY 2026 aims to bolster the sheep industry in the U.S. by enhancing production and marketing initiatives. It supports innovative projects that address long-term challenges and improve infrastructure, business practices, and resource development. The program fosters collaboration among industry organizations to maximize benefits for sheep producers while minimizing duplicated efforts, ultimately strengthening the economic viability of the sector.
Livestock & Ranching
Fiscal Year (FY) 2027 Department of War (DoW) Defense University Research Instrumentation Program (DURIP)
US DOD: U.S. Army Materiel Command
Federal Government
American Samoa, Guam +4 more
US $50,000 - US $3,000,000
The Fiscal Year 2027 Department of War Defense University Research Instrumentation Program (DURIP) aims to enhance the capabilities of U.S. higher education institutions by providing funding for essential research equipment. This initiative supports the education of scientists and engineers in fields critical to national defense. However, for-profit organizations are not eligible for participation, ensuring that funds are directed towards accredited educational institutions.
International Security