Best Large Grants for Nonprofit Organizations in Northern Mariana Islands

The PROTECT Competitive Grant Program aims to enhance the resilience of surface transportation systems, including highways and public transit, through innovative projects. With up to $787 million available from FYs 2024-2026, the program focuses on protecting transportation assets and communities, ensuring they can withstand challenges and recover quickly. This initiative also emphasizes the importance of coastal and natural infrastructure in safeguarding transportation networks. More details can be found in the full NOFO on Grants.gov.

The Level 2 Housing Opportunity Grants, provided by the National Association of REALTORS®, aim to address affordable housing challenges within communities. With a maximum award of $7,500, these grants encourage collaborations among local agencies to enhance housing access. Eligible activities include forums, expos, and studies that promote housing opportunities. Associations can receive one grant per year, and funds are disbursed via a reimbursement process, with requests due by December 19, 2025.

The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.

The NIDCD Mentored Career Development Award supports postdoctoral Au.D./Ph.D. audiologists in their research and career development. This grant aims to foster independence in scientific health-related research relevant to the NIDCD's mission. Key deadlines for applications span from June 2024 to May 2027, providing numerous opportunities for eligible candidates to secure funding and advance their careers in the biomedical and clinical sciences.

The NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) promotes innovative clinical trials on natural products, such as botanicals and dietary supplements. This funding opportunity supports studies that demonstrate significant scientific rationale and preliminary evidence for efficacy. Applications can explore various delivery methods and combinations with existing treatments to enhance outcomes. Funding is available for up to three years, aimed at bridging basic science discoveries into practical clinical applications.

The Great Apes and Gibbons Program Grant, administered by the Arcus Foundation, supports conservation efforts for great apes and gibbons across 24 priority landscapes in Africa and Asia. The program emphasizes sustainable coexistence between humans and wildlife, having awarded over 2,000 grants to more than 500 organizations globally. Funding is not available for individuals or specific lobbying activities, ensuring resources are directed towards impactful conservation initiatives.

The NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) aims to support the career development of promising audiologists through rigorous postdoctoral research in biomedical, behavioral, or clinical sciences. This initiative encourages independent investigation in health-related research relevant to NIDCD's mission. Applications are due on various dates, with the next deadline on June 13, 2024, providing opportunities for advancing research in audiology and related fields.

The Comprehensive Housing Counseling (CHC) and Housing Counseling Training (HCT) NOFO (FY2026) aims to support HUD-approved housing counseling agencies. These agencies provide essential guidance to tenants and homeowners regarding property maintenance, financial management, and literacy. This initiative plays a crucial role in helping individuals secure sustainable homeownership or affordable rentals, while also serving as a safeguard against housing scams and discrimination, connecting clients to various housing resources.

The NIA Expanding Research in AD/ADRD Summer Research Education Program supports the recruitment of early-stage investigators and aims to provide hands-on research experiences in Alzheimer's Disease and related dementias. Targeting high school students, undergraduates, and science teachers, the program enhances STEM education through authentic research opportunities and educational activities. By fostering early exposure to research, it aims to stimulate interest in AD/ADRD careers and address workforce shortages in this critical field.

The National Human Genome Research Institute (NHGRI) is launching a Notice of Funding Opportunity (NOFO) aimed at enhancing genomic research through the development and distribution of high-value resources. This initiative encourages collaborative efforts in genomic resource development and the integration of data science in clinical applications. While applications are not currently being accepted, prospective applicants are urged to prepare meaningful collaborations and projects ahead of the formal solicitation.

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) invites applications for mid-phase clinical trials involving natural products like botanicals and dietary supplements. The goal is to advance clinical testing through robust preliminary data, ensuring these products demonstrate measurable impacts on target engagement. Submission deadlines span from March 2024 to October 2026. Applications must focus on optimizing doses and identifying patient responders to inform future efficacy trials, aligning with NCCIH's research priorities.

The BJA FY 2026 Crisis Response Training Program aims to enhance public safety and law enforcement effectiveness by providing critical training for officers in responding to individuals experiencing behavioral health crises. This funding opportunity supports state, local, and tribal governments in developing programs to improve responses to those with mental health conditions, intellectual disabilities, and other challenges. By equipping officers with essential skills and strategies, the program seeks to ensure safer interventions and better outcomes in crisis situations.

The Telehealth Nutrition Services Network Grant Program, funded by the Health Resources and Services Administration, aims to enhance access to quality health care through innovative telehealth nutrition services. This program focuses on preventing and managing chronic diseases by leveraging telehealth technology, ensuring that individuals receive essential nutrition guidance remotely. With a commitment to improving health outcomes, this initiative will significantly benefit communities seeking better access to healthcare resources.

Service Objects In-Kind Grants support non-profit organizations dedicated to environmental conservation and sustainability. By leveraging their data validation services, they aim to assist projects that promote ecological health and responsible resource management. The program prioritizes applications with clear, measurable objectives and impactful outcomes within one to three years. Organizations with 501(c)(3) status in the U.S. are eligible, while initiatives lacking detailed plans or focusing on generalized education will not qualify. This grant fosters community involvement in environmental stewardship.

The NIA Academic Leadership Career Award (K07) provides funding for established investigators to strengthen research capacity in aging and Alzheimer's Disease. The program supports the development of educational infrastructure, mentorship, and career development activities. Key deadlines for applications include February 12, June 12, and October 12 from 2025 to 2027. This award is specifically for research not involving independent clinical trials, allowing applicants to gain experience in trials led by others.

The Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access program provides critical support to researchers by offering access to contract research organizations and subject matter experts. This funding opportunity aims to facilitate nonclinical therapeutic development efforts, helping investigators navigate the complexities of manufacturing and planning. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional) aims to foster innovative research career development for clinically trained vision scientists. This funding opportunity encourages institutions to develop programs that prepare scholars for independent research careers, particularly in minimal risk clinical trials. Emphasis is placed on recruiting underrepresented groups in research, ensuring a diverse pool of clinician investigators engaged in vision research.

The Eviction Protection Grant Program (EPGP) aims to support low-income tenants facing eviction by offering competitive awards to around 16 nonprofit organizations and government entities. These grants will fund no-cost legal assistance, covering pretrial, trial, post-trial, and alternative dispute resolution services. The initiative, backed by the Department of Housing and Urban Development, is designed to ensure that vulnerable tenants have access to essential legal resources, ultimately reducing eviction rates and promoting housing stability.

The Rooted Pathways Program, initiated by First Peoples Fund, offers essential support to Native-led arts organizations, fostering their growth and stability. This funding empowers these organizations to thrive in their missions, providing unrestricted operating support and participation in a Learning Cohort. Eligible applicants include Native nonprofits and collectives with budgets under $500,000, and the program aims to uplift artists from U.S. federally recognized tribes. This initiative is part of the Wallace Foundation's broader commitment to enhancing well-being in the arts.

The FY26 Reconstructive Transplant Research Program Concept Award encourages innovative research addressing critical issues in reconstructive transplantation. It supports groundbreaking concepts and untested theories, emphasizing creativity and relevance to specific focus areas. Notably, preliminary data presentation is prohibited, yet applications must demonstrate potential for interpretable results. Early-career investigators are particularly encouraged to apply, fostering new talent in this vital research field.

The NIDCD Research Fellowship for Audiologists provides clinical audiologists enrolled in Ph.D. programs with essential research training. This initiative encourages the integration of clinical and translational research, fostering strong research foundations vital for advancing audiology and hearing healthcare. Although applications are not currently being solicited, the program aims to prepare potential candidates for meaningful collaborations and impactful research projects in the biomedical, behavioral, or clinical sciences.

The RFA-FD-23-001 funding opportunity aims to support clinical trials for orphan products targeting rare diseases. It focuses on evaluating the efficacy and safety of treatments to address unmet medical needs. By promoting innovative and collaborative trial designs, the FDA seeks to enhance the approval rates of effective therapies for rare conditions, ultimately benefiting patients and advancing drug development in this critical area.

This grant opportunity from the US Department of Health and Human Services aims to explore the impact of Artificial Intelligence (AI) on healthcare safety. It invites applications to investigate how AI systems can enhance patient safety and improve healthcare delivery. Applicants are encouraged to identify both the benefits of AI technologies and the potential risks to ensure safe implementation. This initiative addresses the need for effective, efficient, and affordable healthcare while safeguarding patient welfare.

The National Institute on Aging, in collaboration with the National Institute on Deafness and Other Communication Disorders, is announcing a Notice of Funding Opportunity (NOFO) aimed at exploring the link between olfactory decline and aging, Alzheimer's disease, and related dementias. This research could reveal olfactory dysfunction as a health indicator in older adults and identify new targets for therapeutic strategies. While applications are not currently being accepted, interested researchers are encouraged to prepare for future submissions.

The Ernest Morgan Memorial Scholarship, managed by CommunityGiving, supports central Minnesota student athletes and leaders to pursue higher education outside their home states. This scholarship aims to expand students' horizons and experiences, with a total award of $5,000 available. Open to high school seniors from specific schools, applicants are encouraged to apply online and demonstrate their leadership or athletic skills. This initiative enhances educational opportunities and fosters personal growth among local youth.

The Health and Health Care Disparities grant aims to support innovative research that addresses the health challenges faced by individuals with disabilities, particularly in communities experiencing health disparities. Key application deadlines span from February 2024 to October 2026. This funding opportunity invites research proposals that explore the underlying factors affecting the health and well-being of these populations, promoting interventions that can lead to significant improvements in health equity.