Best Foundation Grants for Nonprofits in Pennsylvania

The Bay Area Lyme Foundation's Emerging Leader Award supports innovative research in Lyme disease, offering two $150,000 grants to post-doctoral and early-career scientists. Applicants are encouraged to propose proof-of-concept projects that enhance diagnostics or therapeutics. The award seeks to attract talent and foster scientific leadership in biomedical sciences. Evaluation criteria include the potential for novel therapies, scientific rationale, and support from institutions. This opportunity is ideal for those new to tickborne disease research.

The National Multiple Sclerosis Society offers the Sylvia Lawry Physician Fellowships to support MDs in acquiring essential clinical trial training. This fellowship aims to enhance expertise in conducting complex trials for MS therapies, fostering skills in protocol design, patient recruitment, and data analysis. Applicants must have relevant medical training and be engaged in ongoing MS clinical research. The program is vital for addressing the increasing demand for trained professionals in MS clinical trials, contributing to advancements in treatment.

The National Multiple Sclerosis Society offers a Medical Student Mentorship Program that provides a four-week clinical experience for medical students who have completed at least one year of school. This program aims to raise awareness about the challenges faced by individuals with MS and generate interest in careers focused on MS care. Students gain hands-on experience under the guidance of MS specialists, enhancing their understanding of the disease and its management.

The National MS Society offers Harry Weaver Scholar Awards to support emerging researchers in multiple sclerosis. This prestigious award honors Dr. Harry Weaver's legacy and aims to facilitate independent research careers. Eligible candidates must have a doctoral degree and relevant postdoctoral training. The funding is designed to provide salary and grant support for five years, allowing awardees to establish competence in their research area. Applications should align with the Society's Pathways to Cures Roadmap.

The National MS Society's Clinician Scientist Development Awards aim to cultivate promising young investigators in multiple sclerosis research. This program supports postdoctoral fellows with three years of comprehensive training in academic medicine focused on MS. Applicants must hold a clinical degree and be licensed in the U.S. The Society prioritizes research that aligns with its Pathways to Cures Roadmap, which emphasizes stopping disease progression, restoring function, and preventing MS.

The Young Investigator Grants, offered by the Breast Cancer Alliance, aim to support early-career researchers focused on breast cancer. This two-year grant provides up to $125,000 in funding, split across the duration, to facilitate independent research projects. Applicants must be affiliated with U.S. institutions and should not have held major grant support previously. This initiative fosters innovation in breast cancer research, ultimately enhancing survival rates and quality of life for affected individuals.

The Breast Cancer Alliance offers Exceptional Project Grants aimed at enhancing survival rates and quality of life for individuals affected by breast cancer. This grant, amounting to $100,000 over one year, supports innovative research and projects in the contiguous United States. Eligible applicants include clinical doctors and research scientists at any career stage. The funding covers salary and project costs, with indirect costs capped at 8% of direct costs, ensuring comprehensive support for impactful research.

The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to advance the research careers of residents and fellows focusing on radiation oncology and its impact on lung cancer treatment. This $50,000 award supports innovative basic, translational, and clinical research projects. A no-cost extension may be granted at ASTRO and LUNGevity's discretion, but the total project duration cannot exceed two years.

The ASTRO-BCRF Emerging Investigator Award aims to support one early career researcher in breast radiation oncology from underrepresented populations. This initiative by the American Society for Radiation Oncology and the Breast Cancer Research Foundation provides $100,000 for direct costs over one year, emphasizing diversity in the scientific workforce and encouraging eligible individuals to self-identify as part of underrepresented groups in biomedical research.

Manuel And Fillie Garcia Hispanic Scholarship

The Manuel & Fillie Garcia Hispanic Scholarship was established as a permanent fund of Taos Community Foundation in 2011.

The award is available to graduating seniors in Taos and western Colfax counties with preference to Hispanic students pursuing advancement of higher education. The scholarship is available to those applying to 4 year colleges and universities as well as 2 year vocational/trade schools.

The award amount will be determined at the time of committee review. This award is typically renewable for up to three years if a 2.5 GPA is maintained and all required paperwork is returned in accordance with the Scholarship Agreement.

Youth Service America

Youth Service America believes that youth, communities, and our democracy thrive when we all work together for the common good. YSA is a leading global nonprofit that activates young people, ages 5-25, to find their voice, take action, and acquire powerful civic and 21st Century skills as they solve problems facing their communities. YSA supports its activation campaigns with grants, training and resources, and recognition programs for young people and their adult champions. Youth-led projects use Awareness, Service, Advocacy, and Philanthropy (ASAP) strategies to create social and environmental change.

We Serve To Remember Grants

Projects that Engage 100 Youth Volunteers

YSA’s We Serve to Remember 9/11 Day of Service Grants are for organizations, schools, and youth changemakers ages 5-25 to lead service projects on or around September 11, 2026. Programming efforts should also honor and pay tribute to those who lost their lives on September 11, 2001, their families, and those who rose in service in response to that tragedy. (We suggest starting with eleven reflections about 9/11/01 and related ideas for service or service-learning projects.)

Grantees are required to engage at least 100 youth as volunteers in planning and implementing the service activities.

What are we looking for?

• Projects must be youth-led;
• Projects must include elements to honor and pay tribute to those who lost their lives on 9/11, their families, and those who rose in service in response;
• Projects must take place on or around September 11th National Day of Service and Remembrance (Friday, September 11, 2026) – between Friday, September 4 and Friday, September 18;
• Project organizers must make their best effort to recruit and engage youth volunteers who are not usually asked to serve;

Grantees are also required to provide evidence of volunteer participation and number of hours served. Approved documention includes sign in sheets, copies of pre-and-post-surveys, or reports from school attendance or volunteer management system. These documents must contain a unique identifier for each volunteer, such as the volunteer’s full first and last name, their full first name and last initial, or a volunteer/student ID number.

Reflecting on the spirit of togetherness that brought people together in the days, weeks, and months after September 11th, we are especially looking for ideas that bring together all members of the community.

The Autism Speaks Predoctoral Fellowship aims to support early career autistic scientists in their research endeavors. By providing a two-year fellowship that includes a $40,000 annual award, the program seeks to enhance research training opportunities for promising candidates. Fellows will collaborate with leading mentors in autism research, ensuring that individuals with both academic expertise and lived experience can significantly contribute to advancements in the field. This initiative underscores Autism Speaks' commitment to fostering inclusivity and innovation in autism research.

The FY26 Vision Research Program's Investigator-Initiated Research Award (IIRA) offers funding for innovative research addressing eye injury and visual dysfunction due to military exposure. This award supports preclinical to early translational studies aligned with specific focus areas. Unique features include two funding levels and a Partnering Principal Investigator Option. Applications undergo rigorous peer review based on research rationale, strategy, and impact, with potential for sharing with the National Eye Institute for additional funding consideration.

The FY26 Vision Research Program Clinical Trial Award supports the swift execution of clinical trials aimed at improving treatments for service-connected eye injuries and visual dysfunction. This award emphasizes the need for regulatory compliance, including IND/IDE submissions, and requires documentation confirming the application's active status by March 1, 2027. Review criteria focus on clinical impact, research feasibility, recruitment strategies, and ethical considerations, ensuring relevance to military health.

The Changing Aging (CA) Grant supports innovative projects aimed at enhancing economic opportunities for older adults and combating ageism. Priorities include advancing digital equity and promoting aging in place for marginalized communities. Funded by Next50, the grant encourages collaboration among nonprofits and requires an equity-focused approach to project design. Organizations may apply for up to three years of funding, with no maximum request limit, although a pre-application call is necessary for larger requests.

The DoW Vision Research Program's FY26 Translational Research Award aims to accelerate the development of innovative drugs, devices, or clinical guidelines ready for clinical trials. It supports preclinical studies and pilot trials, ensuring alignment with specified VRP Focus Areas. Key features include a requirement for regulatory expertise in drug/device development and a unique Partnering Principal Investigator option. Review criteria focus on research rationale, strategy, feasibility, and impact, enhancing military health outcomes.

About NCCF

For more than 50 years, NCCF has been taking on tough problems to improve the quality-of-life in Northwest CT by supporting nonprofits that speak to the charitable passions of our generous donors.

NCCF is a Community Foundation, a tax-exempt public charity that enables donors to establish funds that support the work of local nonprofits through grants and provide scholarships to local students.

NCCF's Board and Staff champion the causes you care about with smart grant-making designed specifically to adapt over time and provide highly attentive, knowledgeable, and compassionate service that brings donors and organizations together to address community issues.

Scholarship Opportunities and Applications

Through the generosity of fundholders and donors, NCCF has awarded more than half a million dollars in scholarships to assist students in Northwest Connecticut with the cost of higher education.

Michele Farley Pittler Scholarship

• Academic Focus: Unspecified
• Award Average: $1,000

The Mae Casali Bonvicini Scholarship, offered by the Northwest Connecticut Community Foundation, supports Torrington High School graduating seniors aiming for higher education. With awards ranging from $400 to $1,500, this scholarship is designed to ease financial burdens for students who are U.S. citizens or permanent residents in the NCCF’s service area. For over 50 years, NCCF has dedicated itself to enhancing the quality of life in Northwest Connecticut through grants and scholarships.

The Edward W. Diskavich Scholarship, established by the Northwest Connecticut Community Foundation, honors the legacy of Edward W. Diskavich. It aims to support students from Oliver Wolcott Technical High School who are U.S. citizens or permanent residents in the service area. With awards ranging from $300 to $1,000, this scholarship helps alleviate the financial burden of higher education for deserving students, reflecting NCCF's commitment to enhancing community well-being through accessible educational opportunities.

The Foundation for Pennsylvania Watersheds is a grant-making foundation and non-profit organization dedicated to the conservation and protection of the Pennsylvania's water resources.

Raccoon Creek Benefit Fund

Funding through this grant program will support projects that promote the restoration, preservation, protection, or provide other beneficial impacts on water quality in the Raccoon Creek watershed. This Fund was established through a Consent Decree that resolved alleged unauthorized discharges of pollutants in the Raccoon Creek Watershed.

Grantmaking Goals

• Improve water quality and aquatic habitat in Raccoon Creek and its tributaries.
• Address pollution sources, including legacy and ongoing impacts.
• Advance AMD/AML remediation, stream restoration, riparian buffers, and green infrastructure.
• Support monitoring, data collection, and evaluation tied to restoration outcomes.
• Strengthen local organizational capacity to deliver and sustain restoration work.
• Protect land for conservation or public access purposes through acquisitions or easements.
• Engage stakeholders through outreach, education, and communications that will help protect or improve the Raccoon Creek watershed. 

Dennis Jones and Wayne Johnston Memorial Dice Run Scholarship

This fund provides a scholarship for a graduating senior from either Olean High School or Allegany-Limestone Central School who will be attending a 4-year college, with preference for a student planning to study business or business related field (i.e. accounting, finance, marketing, economics etc.)

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Vietnam Veteran’s Moving Wall Fund

The Vietnam Veteran’s Moving Wall Fund Scholarship was established to support the children of local veterans who served in the Vietnam War or subsequent conflicts. It was created in 1990 by the Vietnam Veteran’s Moving Wall Committee using remaining funds originally raised to bring the National Vietnam Veteran’s Moving Wall Exhibit to Glen Oak Park in Peoria, Illinois. The exhibit honors the 58,126 Americans who lost their lives during the Vietnam War.

Myasthenia Gravis Rare Disease Network (MGNet)

The Myasthenia Gravis Rare Disease Network (MGNet) is a consortium of academic medical centers partnering with the Myasthenia Gravis Foundation of America and Conquer MG as well as collaborators in other research groups and industry. We are working together to enhance therapeutic development for this rare disease.

Diseases Studied

Myasthenia Gravis (MG) and its subtypes:

• Early-onset acetylcholine receptor (AChR) antibody (Ab) positive MG, which primarily affects women
• Late-onset AChR Ab positive MG with a disease bias towards men
• Paraneoplastic thymoma-associated MG
• Muscle specific kinase (MuSK) Ab positive
• AChR/MuSK antibody negative MG

Goals, Mission, & Vision

The goal of MGNet is to advance therapeutic development. To do so we have four specific aims:

• Improve the tools scientists and doctors have for performing clinical trials through rigorous monitoring of patients over time and evaluate better measures of how patients are doing.
• Identify objective measures (biomarkers) to show how the disease is responding to treatment and better predict treatment response or side effects, to improve the design of clinical trials and care of patients in clinical practice.
• Enhance the education of young investigators focusing their careers on rare diseases and specifically MG.
• Improve the awareness of scientists, physicians, and the public regarding the unique needs of patients with MG through training of clinician scientists and engagement of the patient and scientific communities in clinical research and therapeutic development.

Pilot and Feasibility Grants

Objectives

MGNet, a NIH-funded Rare Diseases Clinical Research Consortium (RDCRC) in partnership with the Myasthenia Gravis Foundation of America and Conquer MG, is seeking proposals for highly innovative investigations in early stages of development.

The priorities of the Pilot Grant Program are:

• Identification treatment responsive biomarkers
• Assess clinical measures and improve that enhance clinical trial readiness
• Evaluation of therapeutic interventions for one or more of the five distinct sub-types of MG

Pilot studies must be designed to access the resources of MGNet and focused on clinical and translational research, including fulfilling the definition of clinical and translational research and exclusion of animal studies.

Funding

The MGNet expects to fund up to two grants, each at a level of $75,000 (IDCs will be limited to 10% and included in the $75,000). Projects will be funded for 12 months. Selection among the applications received will be based on the recommendations of a review committee. A grant may be renewed for an additional one year with approval of interim report by the same review process and availability of funds. Demonstration of fulfillment of initial aims and justification for additional funding will be required. The request will be required a minimum of three months prior to the initial funding period completion.

Myasthenia Gravis Rare Disease Network (MGNet)

The Myasthenia Gravis Rare Disease Network (MGNet) is a consortium of academic medical centers partnering with the Myasthenia Gravis Foundation of America and Conquer MG as well as collaborators in other research groups and industry. We are working together to enhance therapeutic development for this rare disease.

Diseases Studied

Myasthenia Gravis (MG) and its subtypes:

• Early-onset acetylcholine receptor (AChR) antibody (Ab) positive MG, which primarily affects women
• Late-onset AChR Ab positive MG with a disease bias towards men
• Paraneoplastic thymoma-associated MG
• Muscle specific kinase (MuSK) Ab positive
• AChR/MuSK antibody negative MG

Goals, Mission, & Vision

The goal of MGNet is to advance therapeutic development. To do so we have four specific aims:

• Improve the tools scientists and doctors have for performing clinical trials through rigorous monitoring of patients over time and evaluate better measures of how patients are doing.
• Identify objective measures (biomarkers) to show how the disease is responding to treatment and better predict treatment response or side effects, to improve the design of clinical trials and care of patients in clinical practice.
• Enhance the education of young investigators focusing their careers on rare diseases and specifically MG.
• Improve the awareness of scientists, physicians, and the public regarding the unique needs of patients with MG through training of clinician scientists and engagement of the patient and scientific communities in clinical research and therapeutic development.

Scholar Awards

Objectives

There is a critical need for investigators prepared to conduct clinical and translational research in myasthenia gravis (MG). The MGNet Scholar Program provides individualized training and mentorship in one of two tracks, Clinical Research or Biomarker Development Research.

Award Description

The MGNet Scholar Program provides mentored research training to prepare Scholars for an independent research career in the field of MG. The MGNet Scholar Program is 1 year in duration and selected Scholars receive up to $100,000 to support salary, research costs and didactics with potential for renewal. The program will provide an additional $3,000 to travel to MGNet sites to learn specific skills and/or to scientific meeting(s) to present the results of their research. If available for renewal, the program requires approval after interim report and is contingent on demonstration of adequate progress on the research and career development plan. Indirect costs are not allowed. Scholars are encouraged to transition to NIH (e.g., K award), departmental, or private foundation support for their research and further career development.Research must constitute at least 50% of each Scholar’s professional effort. Each Scholar must form a 2-3-member advisory committee to include a primary mentor, an additional clinician investigator or collaborator, and a MGNet faculty sponsor. The advisory committee will meet with the Scholar at least quarterly to review progress and each Scholar will develop an individual academic career development plan and renew it with the committee at least every 6 months.

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

MidAmerica National Bank’s Employees Children Scholarship Fund

The MidAmerica National Bank’s Employees Children Scholarship Fund was established in 2005 by MidAmerica National Bank to provide scholarship support to the children of bank employees. It is open to students graduating from high school or currently enrolled in an undergraduate college or vocational program.

Ezekiel Hennessey Mitchel Scholarship Fund

The Ezekiel Hennessey Mitchel Memorial Scholarship is designated for graduating high school seniors from Benton, Polk, Lincoln, and Linn Counties pursuing careers in vocations such as the following:

• Home building trades
• Tile setting
• Carpentry
• General contracting
• Electrical
• Plumbing
• HVAC
• Welding
• Entrepreneurship and/or small business development
• Other trades defined by Benton Community Foundation

Students must attain certificates or degrees from accredited trade schools, technical schools, or community colleges. 

The Craft Archive Fellowship supports archival research on underrepresented craft histories in the U.S., including feminist, queer, Black, Indigenous, and other marginalized communities. It offers a $5,000 stipend for scholars and artists to conduct research in chosen archives, encouraging innovative approaches. Participants will present their findings in a virtual program, and their work will be published in Hyperallergic, broadening accessibility and awareness of vital craft research.