Best Foundation Grants for Nonprofits in Pennsylvania

Berks County Community Foundation

Berks County Community Foundation was founded in 1994 to help individuals, families, organizations and businesses achieve their charitable objectives. Since that time, the foundation has grown to manage hundreds of charitable funds. Each year, the funds distribute millions of dollars in scholarships and grants to support local students and nonprofit organizations and causes.

Darrell and Gloria Rank K9 Corps Fund

This fund supports the acquisition, training, and ongoing maintenance of K9 corps for governmental entities in Berks County.

The ACI Foundation's Tribute to the Founders Fellowship supports graduate students in construction, design, education, or materials. Awardees receive a $10,000 educational stipend, recognition in Concrete International magazine, and travel expenses to two ACI conventions. This fellowship aims to foster the next generation of concrete industry leaders through education and mentorship, while also encouraging personal development and career readiness through a structured internship program.

Dr. Jill Biden Scholarship - Biden Breast Health Initiative

Essay:

• Why have you chosen a career in health care or education, and why do you feel it is important to encourage others to adopt a healthy lifestyle?

Awards:

• One time award of $2,500; one award per county. 

The BJA FY 2026 Prosecuting Cold Cases Using DNA program aims to enhance public safety and justice by supporting prosecutors in the investigation and prosecution of violent cold case crimes with developed DNA profiles. This funding opportunity, provided by the US DOJ's OJP Bureau of Justice Assistance, facilitates crucial investigative and forensic activities to increase successful prosecutions and provide resolution for victims and their families. Full applications are due by November 5, 2026.

The Edward C. Roy Jr. Award for Excellence in K-8 Earth Science Teaching, established by the American Geosciences Institute, honors educators who demonstrate exceptional leadership in earth science education. This prestigious award includes a $2500 prize for the winning teacher and a $1500 grant to attend the National Science Teaching Association's annual conference. The award celebrates the legacy of Dr. Edward C. Roy Jr., promoting innovation and excellence in teaching for future generations.

The BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA) aims to enhance the capacity of grantees through dedicated training. It addresses critical operational issues related to overdose responses, targeting illicit opioids and stimulants. The program underscores the U.S. Department of Justice's commitment to public safety, law enforcement support, and the fight against substance misuse. Applications are due by November 9, 2026.

The BJA FY 2026 Upholding the Rule of Law and Preventing Wrongful Convictions Program aims to enhance justice by strengthening the capacity of entities that review wrongful convictions. By supporting partnerships among criminal justice and victims' services, the program seeks to effectively manage post-conviction claims of innocence and prevent future errors. This initiative will help identify actual perpetrators and ensure justice for victims, contributing to public safety and the integrity of the legal system.

The Nelson Foundation's Core Grant Program offers multi-year, general operating support to nonprofit organizations in the Greater Philadelphia Region, focusing on racial equity and social justice. Grants amount to $60,000 over three years, aimed at eradicating racial inequity and social injustice. Eligible organizations must demonstrate a commitment to equity, serve young people and their families, and have total annual expenses under $2.5 million. Applications are accepted from nonprofits with 501(c)3 status.

The Ray Y Gildea Jr Award, provided by the Royal Geographical Society, offers grants of up to £1,000 to support innovative teaching methods in higher and secondary education. This endowed award aims to enhance geography education by funding projects that develop, research, or pilot new approaches, ultimately benefiting students directly. Eligible applicants must be actively teaching in the higher education or secondary school sectors in the UK or USA.

The Digital Wish Donation Program, initiated by Mobile Beacon, aims to provide affordable high-speed Internet access to K-12 schools, colleges, and libraries. For just $10 a month, participating institutions can receive donated mobile hotspots and discounted tablets, enabling them to enhance digital literacy and connectivity among underserved students. This initiative not only breaks down barriers to access but also fosters educational equality, ensuring that all learners have the tools they need to succeed in the digital age.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Edmond and Rima Cabbabe Dedication to the Profession Award

Honors physicians who are committed to expanding knowledge through teaching, conducting research and publishing. Other qualifying virtues include leadership, volunteerism and philanthropic activities in medical and other civic organizations.

Made possible by Edmond Cabbabe, MD, and Rima Cabbabe

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Debasish Mridha Spirit of Medicine Award

Recognizes the work of U.S. physicians who demonstrate altruism, compassion, integrity, leadership and personal sacrifice while providing quality health care to destitute, distressed or marginalized populations in impoverished communities.

Made possible by Debasish Mridha, MD

The Warren Alpert Foundation supports initiatives aimed at enhancing public health through grants exceeding $25,000 for medical research, education, and basic human services. Applications are reviewed quarterly, with deadlines preceding board meetings. The foundation's mission encompasses advancing medical treatments and cures through rigorous research and health education. This commitment empowers various projects that align with their vision of improving community health and fostering innovation in medical practices.

The Haupt Family Fund, established by the Berks County Community Foundation, offers scholarships for local residents pursuing a master’s degree in social work. One scholarship honors Marjorie Haupt and supports students continuing their education in social work. Eligible applicants must be in their final year of a bachelor’s degree or already possess one, with a minimum GPA of 3.0. This fund aims to empower students in their pursuit of advanced education in social work and contribute to the community.

The Warren Alpert Foundation aims to enhance public health by funding medical research, education, and basic human services. With grants under $25,000, it supports initiatives that advance medical treatments and health education. The foundation is committed to fostering innovative research and solutions in healthcare, making a significant impact on community health and well-being.

The Presbyterian Committee on the Self-Development of People Grant supports partnerships with economically disadvantaged groups in the U.S. It aims to empower these communities to take control of their lives and address systemic issues of poverty and oppression. This initiative encourages sustainable change through community-led programs that advocate for justice, human dignity, and economic equity, fostering a transformative impact on their local environments.

National Main Street Center Inc.

Main Street America (MSA) leads an inclusive, impact-driven movement dedicated to reenergizing and strengthening older and historic downtowns and neighborhood commercial districts through place-based economic development and community preservation. We work in collaboration with thousands of local partners and grassroots leaders across the nation who share our commitment to advancing shared prosperity, creating resilient economies, and improving quality of life.

Main Street America was founded in 1980 as the National Main Street Center®, a program of the National Trust for Historic Preservation. Over the past 40 years the MSA network has helped to generate over $115.27 billion in local reinvestment, rehab 345,801 buildings, create 815,894 new jobs, and start 181,647 new businesses in over 2,000 communities. 

Great American Main Street Awards

Main Street America celebrates communities whose successes serve as a model for comprehensive, preservation-based revitalization efforts in their historic downtowns and commercial corridor districts with the Great American Main Street Awards (GAMSA).

Winners represent the diversity of communities in the Main Street America network — small towns, mid-sized communities, and urban commercial districts from every region in the country — and demonstrate the power of the Main Street Approach™. Since the inception of the Great American Main Street Awards in 1995, 118 Main Street programs have been honored.

Selection Criteria: Semifinalists and winners are selected from a nationwide pool of applicants by a jury of Main Street professionals and leaders in the fields of community and economic development and historic preservation. Criteria for winning GAMSA include: strength of the Main Street program in spurring community transformation, commitment to historic preservation, innovative programming, implementation of cross-sector partnerships, community outreach and stakeholder engagement, and ensuring their downtown districts are for everyone. 

Accolades & Ceremony: Semifinalists are promoted through Main Street America’s digital channels and receive media relations support. Winners also receive a short documentary film, a plaque, communications and media relations support, prominent placement on the Main Street America website for two years, and recognition at the 2027 Main Street Now Conference in Detroit, Michigan.

The Philadelphia Cultural Fund (PCF) continues to support the city's arts and culture sector through its FY25 grants, focusing on returning organizations with budgets of $1.5M or less. In this streamlined process, new applicants are not accepted, emphasizing the importance of established organizations in enhancing Philadelphia's cultural vitality. PCF aims to advocate for the arts as drivers of community growth and to promote participation across diverse constituencies, recognizing both emerging and established contributors in the field.

The NIA Research and Entrepreneurial Development Immersion (REDI) program aims to support early-career scientists transitioning to industry through the Entrepreneurial Small Business Transition Award. This initiative fosters entrepreneurial skills while enabling small business concerns to hire postdoctoral fellows and early-stage researchers, enhancing their research capabilities. Focused on mentoring and training, the program is designed to ensure that participants develop essential skills for successful careers in entrepreneurship and scientific development.

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Bob Boggeri Farms Fund

Open to students planning to pursue a degree in Ag or Horticulture. Must be a FFA member and demonstrate financial need. Preference given to students from Hughson.

Award Amount:

• $1,000

The Burroughs Wellcome Fund's Career Awards at the Scientific Interface provide $560,000 over five years to support early-career researchers transitioning from physical and computational sciences to biological sciences. Launched in 1999, these awards aim to enhance academic research careers for U.S. and Canadian citizens, permanent residents, and temporary residents, fostering a diverse and innovative scientific workforce essential for advancing human health.

The Safety, Security, and Privacy for Open-Source Ecosystems (Safe-OSE) program, launched by the National Science Foundation (NSF), addresses vulnerabilities in open-source products and their development infrastructure. It invites proposals to enhance safety, security, and privacy across various types of open-source ecosystems. The program aims to support initiatives that improve resilience against risks, attacks, and breaches, ensuring that OSEs can effectively manage current and future challenges.

About Borealis Philanthropy

Borealis Philanthropy is a philanthropic social justice intermediary that works to resource grassroots leaders and social justice movements for transformative change. We help funders expand their reach and strengthen their impact through donor collaboratives that support a variety of issues, communities, and movements. Borealis is home to nine donor collaboratives, including the Disability Inclusion Fund and Disability x Tech.

DIF x Tech Fund

For the Disability Inclusion Fund at Borealis, part of our efforts for disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. The DIF x Tech initiative, supported by the Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest, invites proposals that are working to bring about transformational change at the intersections of disability, justice, and technology

About the Disability Inclusion Fund and DIF x Tech

The Disability Inclusion Fund (DIF) supports U.S.-based groups run by and for people with disabilities to lead transformational change. The Fund is supported by donors including the Presidents’ Council on Disability Inclusion in Philanthropy, which is comprised of foundation presidents who are committed to disability inclusion as part of improving diversity, equity, and inclusion within philanthropy.

Part of the efforts of disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. This newly launched initiative is housed at the Disability Inclusion Fund (DIF) and supported by Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest. 

DIF x Tech Fund Values

All Disability x Tech award decisions will align with the DIF guiding values. The DIF guiding values are:

• Participation: Movement funding accountable to the disability rights movement. Those impacted by injustice/exclusion should be involved in strategies to advance justice/inclusion.
• Intersectionality: Acknowledging that disabled people have multiple and intersecting social and political identities that can influence their ability to have access and inclusion including race, gender identity, class, sexual orientation.
• Radical inclusion: Deeply committed to removing barriers and ensuring access so that those most affected by intersecting identities can participate, valuing lived experience.
• Leadership of those most impacted by ableism: Emphasis is given to organizations led by people subject to systemic bias and impacted by underrepresentation, particularly disabled people of color, queer, gender nonconforming and women with disabilities.
• Cross-movement solidarity: Intentional focus on collaboration and bridge- building amongst disability justice activists and across movements.
• Sustainability: Resources and tools that support the growth of grassroots disabled-led organizations, and expand operational capacities for ongoing movement building. 

What we fund

We invite proposals that are at the nexus of technology, disability rights and justice. This opportunity may be a good fit for your organization, if you are doing work in any of these areas below:

• Disabled people sharing technical skills and knowledge with others in the community.
• Disabled people leading policy, rights, and disability justice activism work related to tech. 
• Disabled people participate in all stages of the design and development of new tech that will enrich lives of people with disabilities.
• Enabling collective and equitable access to digital infrastructure. 
• Expanding the participation, leadership, and thought partnership of overlooked and under-resourced people with disabilities in all areas of the technology sector.
• Partnerships between disability-focused engineering design labs and maker spaces within schools, centers for independent living, or local nonprofit organizations.
• Permissible Policy Work:
  • We may support nonpartisan policy education and advocacy related to disability and technology. Any lobbying must remain within applicable 501(c)(3) limits and Borealis grant restrictions.

The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.

The National Institutes of Health (NIH) is continuing support for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), which focuses on clinical trials and biomarker validation studies for neurological disorders. This initiative aims to foster innovation in neurotherapeutics by providing essential infrastructure and expertise. The program encourages the establishment of Clinical Coordinating Centers (CCC) and Data Coordinating Centers (DCC) to enhance collaborative efforts. Note that applications are not currently being solicited.

The Pop Culture Collaborative offers Major Grants to support initiatives that promote long-term narrative change and social justice through pop culture. Targeting U.S.-based nonprofits, for-profits, and individuals, these grants aim to engage mass audiences in transformative experiences. With a focus on communities often marginalized, the Collaborative's efforts are designed to foster a pluralistic society where everyone belongs. Grants range from $20,000 to $200,000, depending on project scope and duration, with applications reviewed biannually.

The Paul Purcell "Kids Win!" Annual Baird Education Grant honors the legacy of former Baird CEO Paul E. Purcell, who dedicated his life to educational causes. Established in 2020, this grant supports 501(c)(3) organizations that ensure all children, regardless of circumstances, have access to quality education. Funded by Baird and its associates, it prioritizes programs serving diverse and underserved populations, embodying Purcell's belief that every child deserves the opportunity to succeed.