Best Grants for Nonprofit Healthcare Programs in Pennsylvania

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For more mature concepts aimed at workflow refinement, performance optimization, and generation of proof-of-concept and validation data in relevant public-health use cases in LMICs.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For concepts with preliminary feasibility evidence that are ready to advance from prototype toward an integrated workflow—optimizing performance, broadening assay or pathogen coverage, and generating more robust cost-reduction and performance data.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For technically ambitious or higher-risk, earlier-stage concepts focused on feasibility testing, assay or workflow prototyping, and initial cost-reduction validation. Intended approaches that require focused development to demonstrate viability.

Interface Health Foundation

Interface Health Foundation is a non-profit, 501c3 tax-exempt organization driven by a collective vision of positive change. In healthcare industry policy, understanding the intricate dynamics of funding and its impact on public access, quality, and cost remains paramount. IHF is dedicated to advancing analysis and research into the crossroads of healthcare industry policy, structural frameworks and affordability.

At IHF, our mission is clear: to empower and support student-led research endeavors that shed light on critical healthcare policy and structural issues affecting the public. Through our initiatives, we seek to foster a deeper understanding of the complex dynamics shaping the healthcare landscape.

Interface Health Foundation: Research Grant

Healthcare administrative grant award opportunities are highly competitive and allow candidates to stand out as they enter the job market. Through this IHF grant award, you will get the opportunity to pull together research and content on topics that aren't fully studied or publicized. Depending on the grant topic, some grantees will also have access to a preceptor who is an executive leader in the healthcare field. The preceptor will serve as a valuable resource to the grantee during the development of the research paper and beyond.

An example of a research topic is the impact of legislated acute care nurse staffing levels on the following: nursing professional job satisfaction, the patient experience, and the standard nursing quality indicators as part of nursing Magnet status accreditation.

The Building Communities of Recovery program aims to enhance access to long-term recovery support for individuals facing substance use disorders and co-occurring mental health issues. By empowering organizations to mobilize community resources, this initiative fosters a collaborative environment that promotes sustained recovery. Funded by the Substance Abuse and Mental Health Services Administration, the program emphasizes the importance of community connections in the recovery process, ensuring that individuals receive the support they need to thrive.

The Assisted Outpatient Treatment (AOT) program aims to support adults with serious mental illness (SMI) by facilitating community-based treatment. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), the initiative encourages collaboration with civil courts and community partners. Recipients will implement AOT to ensure that eligible individuals receive necessary support, thereby enhancing their mental health outcomes and promoting recovery.

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Hemophilia Fund

Help with healthcare costs for hemophilia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Chronic Lymphocytic Leukemia (CLL) Fund

Help with healthcare costs for chronic lymphocytic leukemia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See Approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Acute Myeloid Leukemia (AML) Fund

Help with healthcare costs for acute myeloid leukemia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The Rural Residency Planning and Development (RRPD) Program enhances rural healthcare access by establishing sustainable residency programs for physicians. Focused on training in accredited rural settings, the program addresses physician shortages by providing start-up funding for various medical specialties, including family medicine and psychiatry. This initiative aims to ensure long-term sustainability through stable funding sources like Medicare and Medicaid, ultimately preparing physicians to serve rural communities effectively.

The FY 2027 State and Regional Primary Care Association (PCA) Cooperative Agreements aim to enhance the technical assistance provided to Health Center Program award recipients and look-alikes. This initiative focuses on improving access to preventive and primary health care, managing chronic diseases, and ensuring a capable health center workforce. By implementing value-based care strategies and leveraging data for operational improvements, the program seeks to support the health of vulnerable communities effectively.

The FY 2027 Service Area Competition (SAC) funding aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive preventive and primary health care. The initiative supports health centers in delivering essential services, ensuring that vulnerable populations receive the care they need. Service areas for competition are announced periodically, and additional areas may be added if existing centers are unable to continue their services.

The FY 2027 Service Area Competition (SAC) aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive primary and preventive care. This initiative will support health centers in delivering high-quality services, addressing the needs of populations that face barriers to care. Each funding opportunity will specify service areas available for competition, ensuring effective resource allocation to improve community health outcomes.

The FY 2027 Service Area Competition (SAC) aims to enhance health services in underserved communities across the U.S. and its territories. This funding opportunity supports comprehensive preventive and primary health care delivery. Each SAC announcement details service areas available for competition, with potential additional areas announced throughout the year. This initiative is crucial for ensuring continuous access to quality health care for vulnerable populations.

The FY 2027 Service Area Competition (SAC) funding aims to enhance healthcare access in underserved communities across the U.S. by providing grants for comprehensive primary and preventive health services. This initiative addresses essential health needs through competitive funding opportunities, ensuring that health centers can effectively serve their designated areas. Additional service areas may be announced as needed if current centers are unable to continue their operations, thus maintaining service continuity.

The Telehealth Nutrition Services Network Grant Program, funded by the Health Resources and Services Administration, aims to enhance access to quality health care through innovative telehealth nutrition services. This program focuses on preventing and managing chronic diseases by leveraging telehealth technology, ensuring that individuals receive essential nutrition guidance remotely. With a commitment to improving health outcomes, this initiative will significantly benefit communities seeking better access to healthcare resources.

About the Awards

The late Dr. James F. Fries, formerly professor emeritus of medicine at Stanford University, came up with the idea for the James and Sarah Fries Prize for Improving Health in a 1987 ascent of Nepal’s Makalu—one of the world’s highest peaks—when his party became trapped in a severe snowstorm and was ultimately unable to scale the mountain.

Following that experience, Dr. Fries returned to sea level and set about establishing a foundation to support a Nobel-like prize for health that now annually awards a $100,000 prize to an an outstanding leader judged by an expert panel to have done the greatest good for the greatest number of people in the field of health.

In 1992 the Elizabeth Fries Health Education Award was established in honor of Elizabeth Fries, daughter of James and Sarah Fries. The $50,000 prize is awarded annually to an individual judged to have made substantial contributions to their area of health education and health promotion. Sarah Fries remained active in the Fries Awards for Health program until her death in May 2017, and Jim Fries remained active in the awards until his death in November 2021.

The CDC Foundation is honored to partner with the James F. and Sarah T. Fries Foundation, which established and funds the award. As of 2016, the CDC Foundation manages and administers the Fries Awards for Health program, which include the James and Sarah Fries Prize for Improving Health and the Elizabeth Fries Health Education Award.

The CDC's NCIPC is seeking research proposals to tackle implementation challenges in providing linkage to care services for individuals with opioid use disorder (OUD). This initiative encourages partnerships with public health entities and local healthcare champions to create actionable, evidence-based strategies. The goal is to enhance care access and ensure comprehensive overdose prevention services are available in real-world healthcare settings, thereby improving outcomes for those at risk of opioid overdose.

2026 Veterans and Nature Grant

Supporting the health, well-being, and community connection of America's veterans

The National Environmental Education Foundation (NEEF) is pleased to announce grant funding supported by the American Medical Association (AMA) to expand access to nature-based experiences that support the health, well-being, and community connection of America's veterans. AMA has partnered with NEEF to bring an evidence-based health perspective to this effort, underscoring the growing body of research linking time in nature to improved physical and mental health outcomes.

Background

A Pew Research Center survey found that roughly one in four veterans say the transition back to civilian life was at least somewhat difficult. This is especially true for those who return home with stress or trauma. The National Alliance on Mental Illness estimates 11-20% of veterans are believed to experience post-traumatic stress disorder (PTSD) each year.

Nature offers profound restorative benefits for veterans navigating the challenges of post-service life. Time spent outdoors — whether hiking, fishing, camping, or simply sitting among trees — has been shown by numerous studies to reduce symptoms of PTSD, anxiety, and depression, conditions that affect veterans at disproportionately high rates.

Quieting hypervigilance, allowing space for reflection, fostering camaraderie, and reducing isolation are all mental and physical benefits that be found through outdoor recreation. Using America’s public lands to do so provides a powerful and accessible path forward.

Overview

Through the 2026 Veterans and Nature grant, NEEF aims to expand access to nature-based experiences that support veteran health, well-being, and community connection by

• Providing opportunities for outdoor activities on public land that improve the physical and mental health of veterans
• Increasing veterans’ understanding of the physical and mental health benefits of time in nature

The grant will provide up to $10,000 per grantee for projects on federal, state, local, or nonprofit public lands that address physical and mental health in veteran communities.

Examples of project types include outdoor activities, such as hiking, biking, climbing, or fishing; wellness activities, such as forest bathing or meditation; environmental education, such as community science; adaptive programming; and conservation volunteering. Projects are not limited to those listed here.

Building Capacity for Communicating Impact Learning Community RFA

Learn how to communicate about Public Health Infrastructure Grant impact through a new community of practice! Through peer learning, technical assistance, and practical tools, participating teams will build strategic leadership and communications skills to more effectively translate public health achievements into compelling messages for key audiences. All directly funded PHIG recipients (big-city, county, state/territory-level governmental public health professionals) are eligible to apply.

Accreditation Sustainability Learning Community RFA

The Association of State and Territorial Health Officials (ASTHO), through the Public Health Infrastructure Grant (PHIG), is currently accepting applications for participation in a learning lab that will foster health department capacity to build a sustainable public health accreditation culture within their agencies. This opportunity is open to applicants from direct PHIG awardees at the state-, big city-, and county-level.

Healthcare Assistance Grant

The MS Focus Healthcare Assistance Grant assists uninsured individuals with the cost of visiting their MS specialist as well as dental assistance. The grant, which can pay for one visit and one follow-up, is designed to assist those already diagnosed with MS who may need a visit to their treating physician to renew a prescription or handle other important needs. 

Applicants give MS Focus staff authorization to negotiate costs directly with the provider, and the fee is paid directly to the doctor. 

Homecare Assistance Grant

MS Focus understands the daily needs and challenges that must be met by both those with MS and their caregivers. In order to meet these needs in the most timely and efficient way possible, our Homecare Assistance Grant connects you to the best available local services. Should resources within your community not be available, direct support may be provided on a temporary basis.

Available Services include:

• Home Care - Personal hygiene services, light housekeeping, grocery shopping, meal preparation, and transportation to and from appointments are all services that can be provided for a limited time.
• Therapy Visits - Based upon individual need, an appointment with an occupational, physical, or speech therapist can be arranged. Through education and training, these therapists can help to foster independence, self-esteem, and better quality of life for the person living with MS.
• Respite Care - Respite allows primary caregivers the opportunity to tend to themselves, or other family business, with the assurance that their loved one is being cared for by a properly trained individual. This service is provided on a short-term basis for a scheduled period of time. 
• Coming Home - Returning home from a stay at the hospital can be a difficult time of transition. We offer a four-hour visit from an aide who will meet the patient at the hospital, provide transportation home, and then get the patient settled comfortably at home.

The Rural Health Network Development Program aims to enhance health care access in rural areas by supporting integrated health care networks. It offers two funding tracts: the Network Advancement Tract for established networks to overcome operational barriers and the Network Development Tract for early-stage networks to plan and expand services. Both tracts focus on improving care coordination, health outcomes, and operational efficiency, thereby strengthening the rural health care system.

The Rural Health Network Development Planning Program aims to enhance rural health care by fostering integrated health care networks. It focuses on collaboration among entities to bolster local capacity and improve care coordination in underserved areas. By achieving efficiencies and expanding access to essential services, the program seeks to strengthen the overall rural health system while promoting the use of health information technology and exploring innovative care delivery models.

The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.

The Richard L and Freda K Flerlage Foundation

Our Mission

Working to empower underserved populations through small grants in support of literacy, healthcare, reduction of poverty, and the promotion of social and environmental justice.

We are a small family foundation, when possible we aim to support organizations with relatively small operating funds where our small grants will have their greatest possible impact.

Our average grant is $3,800.