Best Operating Grants for Nonprofits in Pennsylvania

The NRF Foundation Rising Stars Scholarship aims to inspire high school students to explore diverse career paths in the retail industry. By encouraging early participation in the NRF Foundation Student Program, the scholarship allows nominated freshmen and sophomores to gain invaluable insights. Eligible students, nominated by university members, receive a $1,000 travel stipend for the program held in New York City from January 8-11, 2026, fostering their academic and professional growth.

OGFA Grow the Future Scholarship

Provides a scholarships to Oklahoma students who are continuing their education in an agricultural-based career/major.

The Claire Morris Lyons Scholarship, offered by the R.O.S.E. Foundation, aims to empower African American students pursuing higher education at Cheyney University of Pennsylvania. This scholarship supports graduating high school seniors and current students with a minimum GPA of 2.5, promoting educational access and success. The foundation is dedicated to uplifting women and families through various initiatives focused on self-sufficiency, financial literacy, and emotional resilience, fostering long-term stability in the community.

The Barbara E. Reed Scholarship, offered by the R.O.S.E. Foundation, empowers high school seniors from Bucks and Montgomery Counties, PA, to pursue education at Historically Black Colleges and Universities (HBCUs). With a minimum GPA of 3.0 and demonstrated financial need, this scholarship aims to enhance educational access for deserving students. Established to support women in transition, the Foundation's initiatives focus on fostering self-sufficiency and resilience through community engagement and educational opportunities.

The Mitchell Patrick Mielnik Scholarship, established by the Community Foundation of Middle Tennessee, honors the legacy of Mitchell Mielnik, a passionate hockey player who exemplified integrity. This scholarship supports scholastic hockey players demonstrating excellence in athletics and academics. By fostering Mitchell's spirit of generosity, the foundation aims to empower young athletes to excel in their personal and professional lives, ensuring a positive impact on the community for years to come.

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is launching a funding opportunity for the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD). This program aims to foster multidisciplinary research on FASD, addressing critical needs such as early identification, intervention development, and mechanisms of alcohol exposure effects. By supporting integrated projects within the CIFASD consortium, the initiative seeks to enhance understanding and reduce the impact of FASD through coordinated research efforts.

The ENF Community Investments Program offers Gratitude Grants between $3,000 and $5,000 to Elks Lodges that have met the GER’s per-member-giving goal. These grants empower Lodges to enhance community service and foster local engagement, supporting initiatives that promote health, education, and welfare. The program exemplifies the Elks' commitment to charity and community improvement, showcasing their dedication to building stronger neighborhoods and helping those in need.

Michelle M. Vasenda Fund

Established in memory of Michelle M. Vasenda, a career nurse who lost her battle to breast cancer in 2009. It was her vision to create a scholarship to help those committed to helping others.

Amount: Varies

• $1,000-$2,000

Number of awards:

• Varies

Renewal:

• Must reapply annually by submission of a new application.

The Michael and Carolyn Stelman Scholarship, offered by the Community Foundation for Southern Arizona, supports students pursuing education in Culinary Arts, Music, or Photography. With annual awards of up to $1,250, this scholarship aims to empower high school graduates from Southern Arizona with a GPA of 2.5 or higher, enabling them to achieve their educational dreams and contribute as future leaders in the community.

The Kubota Hometown Proud Grant is a community initiative that will award ten $50,000 grants in 2025, comprising $25,000 in cash and $25,000 in equipment vouchers. Nonprofit organizations are encouraged to apply for projects that enhance their communities, with applications opening April 3 and closing May 9, 2025. Winners will be announced on September 1, 2025, supporting impactful local initiatives across Kubota's operating districts.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Cushing’s disease or syndrome

Help with healthcare costs for Cushing's disease or syndrome

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Cushing’s Disease or Syndrome, also known as Cushing’s Syndrome, hypercortisolism and hyperadrenalism, is a condition where the pituitary gland releases high levels of the hormone cortisol. It is a rare disease that affects the endocrine system.

The We Rise LGBTQ Scholarship, funded by the Grass Roots Gay Rights Foundation, aims to uplift individuals and the LGBTQ community through educational support. Grants of up to $3,500 for vocational training and $2,500 for higher education will be awarded to applicants dedicated to advancing LGBTQ rights. This initiative encourages diverse candidates, particularly those from underserved backgrounds, to pursue their educational goals and create pathways to financial stability, fostering a brighter future for all.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Amyloidosis

Help with healthcare costs for amyloidosis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Amyloidosis is characterized by a build-up in amyloid protein in specific organs or throughout the body. It is a rare disease that affects multiple systems. Subtypes include hereditary amyloidosis, light chain amyloidosis (AL amyloidosis), and amyloid A (AA) amyloidosis (secondary amyloidosis).

The Thomas T. and Christine Hegeman Wheatley Memorial Scholarship Fund, established in 2006 by Berks County Community Foundation, offers annual scholarships to Berks County residents pursuing education in medical fields such as EMT, Paramedics, Phlebotomy, or Nursing. Priority is given to current EMTs transitioning to Paramedics and applicants with a minimum of 30 hours of volunteer service in a medical capacity. This fund honors the legacy of Thomas and Christine Wheatley.

The Cromwell High School Alumni Scholarship Fund provides a one-time award of $1,000 for West Noble High School seniors residing in Sparta Township. Eligible applicants must plan to attend accredited higher education institutions or vocational training programs. Established by the Cromwell High School Alumni Committee in 2016, the fund aims to support students in pursuing their educational goals while honoring the values and memories associated with their alma mater.

The Affiliate Grants - Early Music Program Fund supports educational initiatives for AMS-affiliated groups focusing on music and culture from before 1600. Established in 2020, it enhances research skills through various programming, including paleography and organology. Eligible applicants are limited to AMS chapters, study groups, and committees, with funding capped at $2000. The program aims to strengthen scholarly networks and requires grant reporting on fund usage and impact.

The Gardner, Prudence E. Memorial Scholarship Fund, managed by the Noble County Community Foundation, supports West Noble High School seniors with a GPA between 3.00 and 3.50. To qualify, applicants must demonstrate a strong work ethic through part-time employment or active participation in extracurricular activities. This scholarship aims to encourage students to excel academically while contributing positively to their communities, furthering the foundation's mission of fostering positive change in Noble County.

The Rossin Foundation, established in 1989 by Peter C. and Ada E. Rossin, is dedicated to supporting qualified nonprofit organizations in Southwestern Pennsylvania. The foundation focuses on five key areas: arts, culture, healthcare, education, and religion. Grants are available to 501(c)(3) tax-exempt organizations and are reviewed semi-annually, although applications are accepted year-round. The foundation’s mission is to give back to the community and empower children and families.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

Established in January 2026, the Irene Zurine Memorial Scholarship Fund awards scholarships each year to support girls and women, traditional or nontraditional students, who are furthering their education.

The Amyloidosis Fund, managed by the HealthWell Foundation, provides essential financial assistance to underinsured patients facing treatment costs for Amyloidosis. The program covers prescription copays, insurance premiums, and related expenses, ensuring that patients can access necessary medications without financial strain. With a maximum award of $8,000, the fund aims to alleviate the burden of healthcare costs for those diagnosed with this complex disease, promoting better health outcomes and quality of life for patients across the United States.

The HealthWell Foundation's Inborn Metabolic or Genetic Bile Acid Deficiency Vitamins and Supplements Fund provides essential financial assistance for individuals facing significant health challenges. By covering copays, deductibles, and related expenses, the fund aims to alleviate the financial burden on underinsured patients. With a commitment to enhancing healthcare access, the Foundation has awarded over $1.2 billion since its inception, ensuring that vital treatments remain accessible to those in need.

The Porphyrias Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from porphyrias, a group of eight disorders characterized by the accumulation of porphyrins in the body. The fund assists with prescription drug copays and insurance premiums, offering up to $4,000 in financial aid. Established to ensure no patient lacks necessary treatment due to costs, the foundation has awarded over $1.2 billion since 2004, supporting more than 1.1 million patients.

The Waldenstrom Macroglobulinemia Fund provides crucial financial assistance to underinsured patients suffering from this rare blood cancer. Through the HealthWell Foundation, the fund helps cover prescription copays, insurance premiums, and treatment-related costs, ensuring access to necessary medical care. With over $1.2 billion in grants awarded, the program has supported more than 1.1 million patients since its inception in 2004. Its mission is to alleviate financial barriers to essential healthcare, allowing patients to focus on their treatment and recovery.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Jenice Schlein Denning Scholarship

This scholarship is to provide assistance with educational expenses for students who cannot otherwise afford attendance at an institution of higher learning. The applicant must be matriculating to a bachelor degree graduate institution, shown academic potential, and be pursuing a 4 year degree at an accredited two-year or four-year college or university. Financial need should be a major consideration for this award.

The scholarship is renewable.

The Greater Susquehanna Valley Competitive Grant Cycle, led by the First Community Foundation Partnership of Pennsylvania, supports 501(c)(3) nonprofits in Montour, Northumberland, Snyder, and Union Counties. The initiative emphasizes diversity, equity, and inclusion, aiming to address systemic issues like racism through community engagement. With a commitment to sustainable development and innovative solutions, the grant encourages collaborations that enhance social impact while fostering a commitment to DEI strategies in organizations.

The Music Performance Trust Fund (MPTF) is a nonprofit organization established in 1948, dedicated to enhancing public appreciation of music. It offers free, live music programs across the United States and Canada, ensuring access to quality musical experiences for diverse communities. Funded by royalties from major record labels, the MPTF collaborates with local arts organizations to promote music education and performance, enriching lives through the power of music at no cost to attendees.

The Music Family Scholarship, funded by the Music Performance Trust Fund, aims to enhance music appreciation and accessibility for children and communities. Established in 1948, the MPTF provides free live music programs across the U.S. and Canada, focusing on underserved populations. Eligible applicants must have a parent in good standing with a Local AFM and be enrolled in higher education for fall 2025. This scholarship encourages artistic expression and community unity through music, fostering enriching experiences for all.