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Best Operating Grants for Nonprofits in Pennsylvania

Find the perfect Operating grants for nonprofits in Pennsylvania on Instrumentl. 10,000+ Operating grants for nonprofits in Pennsylvania in the United States.

10,000+

Available grants

$2.66B

Total funding

$5K

Median grant

10,000+ grants
$2.66B total
$5K median

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10,268 Results based on applied filters

Bee a Rae of Sunshine Foundation – MaKenzi Rae Cash Memorial Animal Compassion Scholarship

Community Foundation of Carroll County
Private
United States
US $4,000
The Bee a Rae of Sunshine Foundation – MaKenzi Rae Cash Memorial Animal Compassion Scholarship, offered by the Community Foundation of Carroll County, aims to support students dedicated to animal welfare. Eligible applicants must be graduating high school seniors from Carroll County, Maryland, with a minimum GPA of 3.0 and at least 125 service hours. This scholarship reflects MaKenzi Rae Cash's love for animals and her commitment to kindness and anti-bullying advocacy.
Education - Higher Education Animal Welfare - General Veterinary Science & Services

Guru Krupa Foundation Grant

Guru Krupa Foundation
Private
India, United States
Unspecified amount
The Guru Krupa Foundation Grant supports charitable causes in social, educational, and religious/cultural areas, rooted in Hindu values. The foundation prioritizes projects that aid the underprivileged, enhance education, and preserve cultural heritage, particularly in India and the US. Eligible organizations must be tax-exempt and demonstrate a commitment to effective accounting practices. The foundation seeks specific projects with measurable outcomes, focusing on direct funding for programs rather than administrative costs.
Academic Scholarship Programs Religion & Spirituality Basic Human Needs

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding - Cycle 3

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.
Health & Medicine Medical Ethics Artificial Intelligence (AI)

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 2

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Wyoming County United Way Grant

Wyoming County United Way Inc
Private
Wyoming County, Pennsylvania
Unspecified amount
The Wyoming County United Way Grant supports 501(c)(3) health and human service agencies serving Wyoming County. This funding opportunity aims to enhance the quality of life for local residents by addressing critical issues in education, income, and health. The grant encourages innovative solutions to improve access to education, basic needs, and health services, ultimately fostering a resilient community. Agencies dedicated to making a positive impact are invited to apply.
Health Care Access & Delivery Human & Social Services Wellness & Healthy Living

Arthur S. Bensell Memorial Scholarship

The Confederated Tribes of Siletz Indians
Federal Government
United States
US $1,000

Confederated Tribes of Siletz Indians

The Confederated Tribes of Siletz Indians is a sovereign nation and has three main branches of government – Judicial, Executive, and Legislative. One of our most important resources is our people.

Education

The Confederated Tribes of Siletz seeks to provide opportunities for Tribal members to reach potential, establish independence and improve quality of life through lifelong learning and education.

Arthur S. Bensell Memorial Scholarship

Arthur S. Bensell was an educator, civic leader, Tribal Council member and Tribal Chairman. He spent many years in service to his community and Tribe as Mayor of the City of Siletz and tribal leader.

Art attended Ohio State University and graduated from Heidelberg College in 1934. During his career with the Bureau of Indian Affairs, he served as a teacher, principal and reservation principal in Minnesota, Alaska and North Dakota. Upon returning to Siletz, Art became involved in tribal business affairs and served many years on the Tribe’s Education Committee and always strived for better educational opportunities for Tribal members.

A memorial scholarship fund was established through the Confederated Tribes of Siletz Indians to honor and award Tribal members in education. The $1000 scholarship is administered by the Tribal Education Committee and strengthened by various fund raising activities throughout the year.

Native American Services Education

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 1

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Mid Career Excellence Award

Association for Women Geoscientists
Association/Society
United States
Unspecified amount
The AWG Mid-Career Excellence Award honors outstanding mid-career women scientists contributing significantly to geosciences. It recognizes achievements across academia, industry, and government, with nominees evaluated on their scientific impact and community service. This prestigious award encourages nominations from the AWG membership and the broader geoscience community, fostering recognition of women's vital contributions in the field. With a commitment to diversity, the award aims to inspire future generations of women in geoscience careers.
Geology Geophysics Earth Science

Cherokee Nation Allied Health Scholarship

Cherokee Nation Foundation
Association/Society
United States
Unspecified amount

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Cherokee Nation Allied Health Scholarship

The purpose of the Cherokee Nation Allied Health Scholarship is to provide financial assistance to Cherokee Nation citizens pursuing college degrees in health care fields to support their readiness to contribute to and grow within the Cherokee Nation reservation labor market. This scholarship is competitive and subject to availability of funding.

The foundation also offers a Nursing Scholarship and if funding allows, scholarships will be available for degrees in health fields other than nursing to meet any current workforce need in the Cherokee Nation Health Services department.

Education - Higher Education Health & Medicine Academic Scholarship Programs

John F Long Foundation Grants

John F Long Foundation Inc
Private
United States
Unspecified amount

Mission: A non-profit, charitable, Private Foundation established in 1959 by the Long family to support local charities, schools, education events and general community needs.

Grants

Our approach to grant requests focuses on fostering local neighborhood vitality and excellence. The John F. Long Foundation supports local non-profit organizations that promote this objective. The Foundation looks for groups who are working to help themselves, help their own communities, and help others like themselves through self-empowering, community organizing efforts. To be eligible for consideration, the grant request must meet the following criteria:

  • Funds’ use must have measurable benefits
  • Your organization must have good management, a solid financial background, well-established administration policies and Board of Directors
  • The grant request must be precise and complete, providing necessary detail
  • The Foundation Questionnaire is to be completed in its entirety
  • The grant request amount and time frame must be clearly communicated, i.e. one-time grant, ongoing support, or special project
  • If your request is for a particular event or program, providing a budget is always helpful
  • Requests for grants of $1,000.00 or more, as well as groups we have not funded within the past two years, must: (i) Provide financial reports/statements for past and current fiscal year; (ii) Provide a list of past donors going back no more than two years.
Community Development & Revitalization Educational Access & Equity

Asian Cultural Council: Organization Grant

Asian Cultural Council Inc
Private
Afghanistan, Bangladesh +18 more
Up to US $50,000
The Asian Cultural Council (ACC) offers Organization Grants to arts and culture organizations in Asia and the U.S., promoting cultural exchange through travel and collaborative activities. These grants support immersive experiences, research, and access to artistic communities, fostering international dialogue and relationship-building. Organizations must be nonprofit or educational institutions, legally registered in eligible regions, and demonstrate a minimum of five years of relevant programming. ACC provides additional support to enhance project feasibility.
Art & Culture Cross-Cultural Understanding & Exchanges Artist Training & Development

Advancing Technologies for Spatiotemporal Omics in Live Tissue

Chan Zuckerberg Initiative Foundation
Private
United States
US $250,000 - US $500,000
The Chan Zuckerberg Initiative is calling for transformative research proposals through the Advancing Technologies for Spatiotemporal Omics in Live Tissue program. This initiative seeks to combine innovative engineering with biological research to explore the complex molecular dynamics of health and disease. By fostering collaboration among scientists and AI experts, this funding aims to unlock new high-precision interventions, significantly advancing our understanding and management of health issues.
Bioengineering Biotechnology Synthetic Biology

Giving Circle for the Advancement of Women (GCAW) Award

The Society of Interventional Radiology Foundation
Association/Society
Canada, United States
Unspecified amount

The Society of Interventional Radiology Foundation

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Giving Circle for the Advancement of Women (GCAW) Award

Provide career development opportunities for women in interventional radiology. GCAW is dedicated to engaging all generations of women in interventional radiology through the power of community philanthropy.

Health & Medicine Biomedical Imaging

Collins Medical Trust Grant

Collins Medical Trust
Private
United States
Up to US $40,000
The Collins Medical Trust Grant, established in 1956, supports health-related research and professional education for tax-exempt organizations. Eligible applicants include institutions with approved tax status and a commitment to equal opportunity. Early career investigators are encouraged to apply, but funds cannot be used for individual benefits or political activities. The Trust prioritizes projects in Oregon and does not support product development for industry. Applications are accepted thrice yearly, with specific deadlines for timely consideration.
Diseases & Conditions Health & Medicine Medical Education & Professional Training

Jason Reynolds / Simon & Schuster Travel Grant

American Library Association (ALA)
Association/Society
United States
Up to US $3,000
The Jason Reynolds / Simon & Schuster Travel Grant supports five black/African American youth and teen services librarians annually. Each grant, ranging from $1500 to $3000, covers expenses for travel, housing, registration, and attendance at the ALA Annual Conference, including the Coretta Scott King Awards Breakfast. This initiative aims to empower underrepresented librarians in their professional development and community engagement.
Library Services Black American Services

ASTRO-AAPM Physics Resident/Post-Doctoral Fellow Seed Grant (1 year)

American Society For Radiation Oncology
Association/Society
United States
Up to US $100,001
The ASTRO-AAPM Physics Resident/Post-Doctoral Fellow Seed Grant supports early-career scientists in radiation oncology physics research. Jointly funded by AAPM and ASTRO, this grant aims to foster innovation in the field, with up to two awards of $50,000 each available. Eligible applicants include medical physics residents and post-doctoral fellows who are active members of ASTRO and AAPM. This initiative strives to enhance the next generation of researchers, ensuring a commitment to advancing radiation oncology.
Cancer / Oncology Physics

Jim and Shirley Cook Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
US $750
The Jim and Shirley Cook Scholarship offers a $750 award for graduating high school seniors pursuing higher education at accredited institutions. Applicants must demonstrate financial need through FAFSA-SAI and provide evidence of community service and extracurricular involvement. Preference will be given to candidates with leadership experience in FFA or the GO CAPS program, specifically those studying Mechanical Engineering, CNC programming, Welding, or Machine Tool Technology. This scholarship aims to support students who embody commitment and community engagement.
Vocational & Trade Education Education - Higher Education Mechanical Engineering

Tommy Wilson Memorial Grant

Society Of Health And Physical Educators
Private
United States
US $500 - US $1,500
The Tommy Wilson Memorial Grant, established by Dr. George T. Wilson and his wife Irene, honors their son Tommy, who had cerebral palsy. This grant supports recreational programs for individuals with disabilities and aims to positively impact their lives. Applicants must be nonprofit organizations with a successful history of programming for individuals with disabilities. The grant prioritizes programs serving economically disadvantaged individuals and may only fund applicants once every five years.
Recreation Disability Care & Services Poverty Alleviation & Services

MPS Physics Research Programs (MPS Physics)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.
Physics Astronomy & Astrophysics Geophysics

Peter and Huberdina Weller Scholarship

Community Foundation Of The Holland Zeeland Area
Private
United States
Unspecified amount

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Peter and Huberdina Weller Scholarship

  • Graduating senior, graduating early college student, or current college student from a high school within the greater Community Foundation service area
  • Enrolling/enrolled at an accredited post-secondary school within the United States
  • Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
  • GPA of 3.0 or greater
  • Intention to pursue educational opportunities and a career in horticulture or the biological sciences with an emphasis on botany
  • All other qualifications being equal, tie-breaking consideration will be given to students of color
  • Previous recipients of the award are encouraged to reapply.
Education - Higher Education Horticulture & Gardening Plant Science

Transforming Prison Cultures, Climates, and Spaces Grant

US Department of Justice: Bureau of Justice Assistance
Federal Government
United States
Up to US $1,000,000

BJA FY 25 Invited to Apply for Transforming Prison Cultures, Climates, and Spaces

Basic Information

The Office of Justice Programs (OJP) is committed to advancing work that furthers the U.S. Department of Justice's (DOJ) mission to keep our country safe and secure and uphold the rule of law and protect the rights of American citizens. OJP provides federal leadership, funding, and other critical resources to directly support law enforcement, combat violent crime, protect American children, provide services to American crime victims, and address public safety challenges, including human trafficking and the opioid crisis.

This is a notice of funding opportunity (NOFO) for the BJA FY 2025 Invited to Apply for Transforming Prison Cultures, Climates, and Spaces. Originally released in FY23, BJA's Transforming Prison Cultures, Climates, and Spaces program funded the development and initial implementation of the Safe Inside Initiative, which supports state departments of corrections (DOC) in their efforts to improve safety, security, and reduce recidivism, particularly among prisons facing acute workforce challenges. Through the Safe Inside Initiative funded via this program, state DOCs will receive highly specialized and technical training to help them effectively recruit, train, and retain qualified staff, and streamline operations in response to workforce trends.

Community / Public Safety Correctional Systems & Prisons

Mellon Foundation Native American Scholars Initiative (NASI) Digital Knowledge Sharing Fellowships

American Philosophical Society
Association/Society
Philadelphia County, Pennsylvania
US $3,000
The Mellon Foundation Native American Scholars Initiative (NASI) offers short-term Digital Knowledge Sharing Fellowships, inviting global applications to support digital projects that connect archives with Indigenous communities. Selected fellows will participate in a workshop at the American Philosophical Society in July 2026 to share their progress and collaborate on challenges. This initiative seeks to enhance access to archival materials, promoting community engagement and preserving cultural knowledge for future generations.
Native American Culture & Heritage Technology Access & Digital Literacy

AOAP Swim Lesson Grant

Association of Aquatic Professionals
Association/Society
United States
Up to US $500
The AOAP Swim Lesson Grant aims to enhance drowning prevention by providing financial support to aquatic facilities for swim lessons and life jackets. With a minimum allocation of $10,000 annually, the program seeks to offer at least 100 free lessons to low-income participants and distribute 500 life jackets each year. It encourages non-profit organizations to apply, ensuring a focus on education and safety in aquatic environments. This grant represents a significant step towards making swimming accessible and safe for all.
Community / Public Safety Swimming

Kazanjian Economics Foundation Grant

Calvin K. Kazanjian Economics Foundation
Private
United States
US $10,000 - US $25,000
The Kazanjian Economics Foundation Grant focuses on enhancing economic literacy across various educational settings. With a history of over 70 years, the foundation supports projects that deliver economic education to youth, particularly in non-school environments. It emphasizes teacher training and initiatives for underserved communities, while also promoting behavioral economics and entrepreneurship. The foundation welcomes letters of interest year-round, with recommended deadlines of March 10th and September 10th for grant cycles.
Economics Financial Literacy

AmeriCorps VISTA Request for Concept Paper

Volunteer Mississippi
State/Local Government
United States
Unspecified amount

AmeriCorps Vista

AmeriCorps is the federal agency that improves lives, strengthens communities, and fosters civic engagement through service and volunteering. AmeriCorps brings people together to tackle the country’s most pressing challenges through national service and volunteerism. AmeriCorps members and AmeriCorps Seniors volunteers serve with organizations dedicated to the improvement of communities and those serving. AmeriCorps helps make service a cornerstone of our national culture.

Founded in 1965, AmeriCorps VISTA is a federal anti-poverty national service program designed to provide resources to nonprofit organizations and public agencies to strengthen efforts to address poverty and poverty-related problems in the United States. In 1993, VISTA was incorporated into the AmeriCorps network of national service programs administered by the Corporation for National and Community Service, now known as AmeriCorps.

AmeriCorps VISTA Request for Concept Paper

Projects must be developed in accordance with AmeriCorps VISTA core principles:

  • an anti-poverty focus
  • community empowerment
  • sustainable solutions
  • capacity building

Project applications must address one of the following areas:

  • Economic Opportunity
  • Healthy Futures
  • Education
  • Veteran and Military Families
Education Military & Veterans Services Economic Services & Development

Eleanor Campbell Charitable Fund: College Scholarships

Eleanor Campbell Charitable Fund
Private
United States
Unspecified amount
The Eleanor Campbell Charitable Fund offers competitive scholarships to high school seniors and current college students from the Deering, Hillsborough, and Weare areas. With a history of over $900,000 awarded, the fund emphasizes academic achievement, financial need, and community involvement. Scholarships are available for full-time post-secondary education, with the potential for renewal based on continued eligibility. Announcements of winners occur during high school graduation ceremonies, ensuring recognition of their hard work and dedication.
Education - Higher Education Health & Medicine Religious / Theological Education

Jim and Ruth B. Daley Family Fund

Berks County Community Foundation
Private
Berks County, Pennsylvania
Unspecified amount
The Jim and Ruth B. Daley Family Fund, established by the Berks County Community Foundation, aims to support Berks County residents pursuing higher education. This fund prioritizes living expenses, professional testing fees, and books, alongside tuition. Eligible applicants must have completed at least one semester of higher education, with a preference for those from Berks County or studying Electrical Engineering. Notably, high school seniors are ineligible for this award.
Education - Higher Education Electrical Engineering Academic Scholarship Programs

Operating Grants for Nonprofits in Pennsylvania Highlights

Looking for operating grants for nonprofits in Pennsylvania?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Pennsylvania recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Pennsylvania

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Operating grants for nonprofits in Pennsylvania grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Operating grants for nonprofits in Pennsylvania over $25K in average grant size

88 Operating grants for nonprofits in Pennsylvania over $50K in average grant size

45 Operating grants for nonprofits in Pennsylvania supporting general operating expenses

300+ Operating grants for nonprofits in Pennsylvania supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Education - K through 12

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Pennsylvania?

Most grants are due in the second quarter.

Q1
27.0%
Q2
28.4%
Q3
23.4%
Q4
21.2%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Pennsylvania?

Grants are most commonly $28,750.

$500 $500 Min.
$28,750 $28.8 K Median
$465,890 $465.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Pennsylvania?

Grants are most commonly $120,832.

$120,832

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Pennsylvania year over year?

In 2024, funders in Pennsylvania awarded a total of 114,767 grants.

2022 101,760

2023 105,380

2024 114,767

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Pennsylvania given out in Pennsylvania, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Pennsylvania changing over time?

Funding has increased by 39.90%.

2022 $9,486,595,381

2023 $9,869,112,363
4.03%

2024 $13,806,751,647
39.90%

Pennsylvania Counties That Receive the Most Funding

How does grant funding vary by county?

Montgomery County, Philadelphia County, and Allegheny County receive the most funding.

County Total Grant Funding in 2024
Montgomery County $11,058,341,664
Philadelphia County $2,487,099,923
Allegheny County $1,915,534,930
Chester County $846,675,579
Centre County $563,407,306