Best Operating Grants for Nonprofits in Pennsylvania

The Student Research Grant in Audiology, offered by the American Speech-Language-Hearing Foundation, supports doctoral students conducting research in clinical and rehabilitative audiology. Up to three grants of $2,000 each are available for eligible students enrolled in accredited programs in the U.S. This initiative honors the legacies of Ira Ventry and Brad Friedrich, who made significant contributions to the field of audiology. Interested candidates must submit proposals for research projects to be initiated in this vital area.

The PPL Foundation's Empowering Communities Grants provide up to $50,000 to support initiatives that enhance education, workforce development, and community revitalization. Targeting nonprofits in the PPL Electric Utilities region, these grants focus on environmental stewardship, economic development, and promoting sustainable communities. Eligible organizations must demonstrate their impact in improving community quality of life, with a commitment to diversity, equity, and inclusion. Applications are limited to one per organization per grant cycle.

The Bill Monroe Memorial Scholarship, managed by the Brown County Community Foundation, offers financial support to graduates of Brown County High School pursuing a full-time baccalaureate degree in music or a related field. This scholarship is open to current and previous graduates, including those participating in Bluegrass music mentoring programs. The foundation has a strong focus on education and has facilitated numerous scholarships, enhancing opportunities for local students since its establishment.

This program aims to enhance education for healthcare professionals regarding new therapies and patient management in ulcerative colitis (UC). It focuses on multi-channel educational strategies to address the evolving landscape of UC treatment. Key areas include educating on new oral therapies, transitioning to advanced therapies, and managing isolated proctitis. Organizations such as healthcare institutions and medical education companies are eligible to apply, ensuring a comprehensive approach to improving UC care.

The Sloan Indigenous Graduate Partnership (SIGP) Scholarship Program, funded by the A.P. Sloan Foundation, aims to support Indigenous graduate students in STEM fields. This program, a collaboration among the Montana University System institutions, offers scholarships, professional development, and networking opportunities to enhance the academic journey of Indigenous students. With awards of $20,000 for M.S. and $40,000 for Ph.D. candidates, the SIGP seeks to increase the number of Indigenous scholars earning advanced degrees in science and engineering.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

John W. Burandt Scholarship

Purpose of Scholarship

To provide support for tuition, fees, books, and other expenses associated with post-secondary education for dependents of firefighters residing in the city of Rochester, NY.

Number and Size of Awards

One award of $2,000; paid in the Fall and and divided equally between the Fall and Spring semesters.

Donor Information

This scholarship was established by Mrs. Lorene (Rene) Burandt in honor of her husband, John W. Burandt, a dedicated firefighter who served the Rochester community for 30 years.

The Changemaker Accreditation Grants support birth centers in achieving and maintaining accreditation by covering up to 100% of the initial or annual fees required by the Commission for the Accreditation of Birth Centers. This initiative honors the pioneers of the birth center movement and aims to assist centers that demonstrate financial hardship and a commitment to serving low-income communities. Special consideration is given to those fostering public education and located in rural areas.

The Central Pennsylvania Food Bank's Youth Programs address child hunger, with initiatives like School Pantries, Kids Cafés, BackPack programs, and Summer Meals. These programs provide nutritious food to food-insecure children and families, ensuring they have access to healthy meals during school breaks and throughout the year. With over 1.2 million pounds of food distributed annually, these efforts support thousands of households, fostering both nutritional and educational development for children in central Pennsylvania.

Foundation for Delaware County

Our Mission

To ensure an equitable, vibrant future for Delaware County by promoting generosity, inspiring participation and partnership across our communities, and improving the quality of life for all.

The Foundation for Delaware County works with individuals, private foundations, nonprofits, and businesses to move Delaware County forward.

Partners in Giving RFP

This collaborative effort between The Community’s Foundation (TCF) and The Foundation for Delaware County (the Foundation) is designed to support nonprofits serving Delaware County by reducing duplication, improving access to resources, and creating a more seamless funding experience. Through greater alignment of processes, shared expertise, and coordinated opportunities, nonprofits can more easily navigate support systems, strengthen their organizational capacity, while maximizing the collective benefit to the community.

Rather than duplicating efforts, TCF and the Foundation will work side-by-side to identify where joint action can yield greater results, whether through shared tools that make grant applications more accessible, coordinated timelines that reduce administrative burden for grantee partners, or aligned funding priorities that direct resources toward the community’s highest needs.

This approach fosters stronger relationships between the two foundations and with the nonprofit sector, builds mutual understanding of local challenges and opportunities, and reinforces the shared commitment to equitable, high-impact philanthropy in Delaware County.

This spirit of partnership is reflected in specific initiatives that make it easier for nonprofits to engage with both foundations and focus more of their energy on delivering impact.

Funding Priorities

For the 2026 Partners in Giving Grant cycle, this collective effort will consider awarding grant funds to organizations that focus on community development, health, hospice and homecare, support for cancer survivors, and youth development.

Eligible organizations may apply for funding under any of the funding priorities, selecting one area that aligns most closely with their mission and proposed activities. The application should demonstrate outcomes within at least one of the following types of outcomes:

Types of Outcomes

Safety Net – Provide basic assistance to ensure well-being and prevent dire outcomes for individuals facing economic hardship, health issues, or other challenges.

Preventive – Intervene before problems arise, reducing factors that lead to negative outcomes and enhancing protective factors that contribute to well-being and success. This can include Out-Of-School Time programming.

Systems Change – Target the root causes of social issues to change structures, such as public policies and regulations that enable systems to function better.

Organizational Development – Strengthen effectiveness and capacity through planned change in an organization’s processes, systems, structures, or leadership.

Eligible organizations may submit one application to support their efforts in advancing the funding priorities above. Organizations can apply for a single year only.

Partners in Giving: Cancer Survivors

The 2026 Partners in Giving initiative will consider awarding non-clinical grants of up to $15,000 to organizations that provide education and supportive services to assist cancer survivors living in Delaware County.

All grant proceeds must be used to provide programs and services in and for Delaware County residents.

TryMarine Grant

The Reservoir Fish Habitat Partnership (RFHP) is seeking candidate pilot sites for evaluating two water quality treatment technologies—TryMarine and Oase Water Technology—in small urban fishing lakes (1–3 acres).

Urban fishing lakes are important community resources, providing accessible angling opportunities and supporting local outdoor recreation. Many of these lakes experience nutrient‑driven water quality impairments such as algal blooms, low dissolved oxygen, and reduced water clarity. These issues degrade fish habitat and diminish angler satisfaction.

This pilot initiative aims to identify lakes where these technologies can be tested to determine their effectiveness, feasibility, and potential for broader application across the RFHP network.

Objectives

Water Quality & Habitat Objectives

• Reduce nutrient concentrations (total phosphorus, total nitrogen).
• Improve water clarity and reduce turbidity.
• Reduce harmful algal blooms (HABs).
• Increase dissolved oxygen stability to support sportfish populations.
• Improve habitat conditions for stocked and naturally occurring fish species.
• Reduce internal nutrient loading from sediments.

RFHP Program Objectives

• Demonstrate scalable tools for improving fish habitat in small urban lakes.
• Support community‑based fisheries enhancement.
• Provide case studies and data for future RFHP guidance.
• Strengthen partnerships among agencies, municipalities, NGOs, and angling groups.

Patricia Schroder Memorial Scholarship

Pat had a big heart for helping others and devoted her life to assisting, teaching, and coaching students with disabilities. She worked as a special education teacher's assistant at various schools across the Evergreen School District after earning her Masters, she moved to White Salmon, Washington, where she taught at Columbia High School. In 1994, she moved back to Vancouver and accepted a teaching position at Camas High School where she taught social studies and special education. She retired in 2010 after more than 16 years with the Camas School District.

Pat had a big heart for helping others. She loved and took interest in many of her students throughout her teaching career. She was also actively involved in Special Olympics as a coach and volunteer in addition to providing temporary respite care relief for families of children with special needs.

Additionally, Pat developed a passion for politics at an early age when she first served as a government page at the Washington State Capitol during her senior year in high school. She became an active member in Washington State Democrats, where she attended state democratic caucuses and managed senatorial and legislative campaigns. She also successfully spearheaded the passage of levy and bond election campaigns to support educational programs in the Evergreen School District. Her love for politics later resulted in her running and being elected as Mayor of the city of White Salmon in 1992, where she held the post for two years. Pat enjoyed visiting Frisco, Texas to spend time with her family whenever she could.

Award Amount

2 scholarships are awarded each year. Awards will likely be between $1,000-$1,400.

The Juan Diego Guadiana Legacy Foundation Scholarship supports students from Las Cruces High School or Doña Ana County, especially those affected by cancer treatment or pursuing health-related fields. This scholarship is open to various backgrounds, including BiPOC and LGBTQIA+ communities. The foundation aims to empower students at different educational stages, ensuring they have the resources necessary to thrive in their academic and professional journeys.

 YWCA Clark County Chan Barnett Scholarship

The mission of the YWCA Clark County Scholarship is to advance, support and promote education for women returning to the workforce.

The YWCA Clark County Scholarship was founded in 1994 by Channing R. R. Barnett with the purpose of helping women acquire training they need to become employable and self-sufficient.

Channing was sixty when she left her marriage. She had been a wife and mother for thirty two years - and worried she had no 'marketable skills' with which to support herself. Conquering her fears, Chan enrolled in Clark College's Displaced Homemakers Program. With the support of other women, Chan began to explore and develop her own talents. Drawing on her strong conviction to 'paddle her own canoe' she decided to make the most of her resources.

Reading the Wall Street Journal from cover to cover, taking advantage of every free resource she could find, and having the confidence to call investment brokers and ask lots of questions eventually paid off! As Chan said, she went from, "just having my toes in the stock market, then my ankle, and now I'm swimming up to my neck!"

The support she received from YWCA during this challenging time inspired Chan to start YWCA Scholarship. Her personal success is an inspiration to us all; it is her hope to pass along that inspiration to other women who face similar challenges.

Award Amount

One to two scholarships in the range between $1,000 - $4,000 may be awarded at the scholarship committee's discretion.

The First Community Foundation Partnership of Pennsylvania of Pennsylvania brings together people, partners and places to grow local giving and investment, strengthen area organizations and results, and take on the critical issues and efforts needed to build vibrant communities and a thriving north central Pennsylvania region. We guide the philanthropic gifts of donors by investing and administering funds to charitable programs and purposes via grants, scholarships, endowments and more. While our efforts are focused in Lycoming, Montour, Northumberland, Snyder and Union Counties, we also reach into Bradford, Clinton, Columbia, Potter, Sullivan and Tioga Counties through donors and their geographic area funds and scholarships.

Margaret E. Waldron Memorial Fund

The Margaret E. Waldron Memorial Fund was created in 1976 to support the charitable, educational, religious or health care purposes in and around the Borough of Muncy. The Fund provides grants annually through a competitive grant process to nonprofit organizations serving the residents of the Muncy Area. 

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Patient Travel Grant Program

A mesothelioma diagnosis and treatment often require the patient and their family to incur numerous expenses as part of their treatment. Travel to treatment, alone, can cause a significant financial burden on the patient, which might even cause the patient to not seek treatment away from home, even it’s their best option. To ensure that all patients have the ability to seek specialized help and treatments, the Mesothelioma Applied Research Foundation administers its Travel Grant Program.

The Meso Foundation’s Patient Travel Grant Program, founded by Mary and Bob Cosentino, provides travel grants to patients and one caregiver traveling for an initial consult and/or for clinical trial treatments.

• The type of eligible travel must fall into at least one of these two categories:
  • One trip for one initial consultation with a mesothelioma specialist.
  • Multiple trips to participate in an interventional clinical trial (found on clinicaltrials.gov).

The F26AS00023 FY2026 Prescott Marine Mammal Rescue and Response Grant Program offers crucial financial support for marine mammal rescue efforts. This initiative aims to assist eligible participants in the recovery and treatment of stranded marine mammals, provide emergency response to stranding events, and enhance scientific research on marine mammal health. The program prioritizes applications that effectively address species-specific needs and bolster the capacity of stranding networks, ensuring the welfare of marine wildlife under the management of the U.S. Fish and Wildlife Service.

The Lam Research Core Values Scholarship, offered by the East Bay Community Foundation, supports high school seniors from specific districts in California and Oregon. Recipients are awarded $10,000 over four years, promoting educational success. Eligible students must exemplify Lam's Core Values, maintain a GPA of 2.7 or higher, and plan to attend a college or technical school. This scholarship aims to empower diverse youth in their educational pursuits and foster community development.

The State Maternal Health Innovation Program (SMHI) aims to enhance maternal health across states by addressing critical gaps. It focuses on improving service quality, developing a skilled workforce, and utilizing enhanced data capabilities. Through innovative programming, the initiative strives to significantly reduce maternal mortality and severe maternal morbidity, ensuring better health outcomes for mothers and their families.

The MSA Climate Change Research Award, offered by the Mycological Society of America, supports innovative research addressing the impacts of climate change through the lens of fungal studies. Ideal candidates include undergraduates, graduate students, and post-doctoral scientists who are MSA members or have applied for membership. This award encourages collaboration and aims to disseminate research findings to the global scientific community, fostering inclusivity across various demographics.

The Maternal and Child Health (MCH) Nutrition Training Program aims to enhance the nutrition and overall health of mothers and children. This initiative focuses on interdisciplinary graduate education, equipping a skilled workforce to support Title V and other MCH programs. It seeks to expand nutrition education and career pathways while improving access to quality nutrition services. Trainees will gain practical experience through placements at health centers, ultimately benefiting families and communities.

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

Pediatric Dermatology Research Alliance Inc 

PHACE syndrome is a neurocutaneous syndrome characterized by large segmental infantile hemangiomas of the face and scalp in association with congenital anomalies that may affect the posterior fossa of the brain, cerebral and cervical arteries, heart, and/or eyes. LUMBAR syndrome is the lower-body counterpart of PHACE, characterized by large segmental infantile hemangiomas of the lumbosacral, buttock or pelvic regions associated with urogenital, spinal, bony, anorectal, and/or renal abnormalities. Those affected experience a wide range of comorbidities with significant psychosocial impact. We invite proposals for clinical research that improves diagnostic approaches, enhances quality of life, and addresses key aspects of disease burden and management.

Applications may be submitted by either a single investigator or multiple investigators at multiple institutions. A total of $40,000 is available and may be awarded as one large-scale project or as multiple smaller awards, depending on the number and quality of applications received. Equal consideration will be given to projects in either of the two award formats with decisions to be based upon merit and available funds.

Focus

Research should focus on PHACE and/or LUMBAR syndromes. Priority will be given to investigators who have not previously served as the senior investigator on an R01 NIH grant or equivalent, and to studies that include multidisciplinary teams with active roles for early-career investigators. Proposals that meaningfully integrate patient perspectives are strongly encouraged.

Important Details

• Up to $40,000 will be funded to support one large-scale project for up to two years, or as multiple awards for smaller-scale projects

The Hearst Foundation: Education Grant aims to support outstanding nonprofits that promote education across various levels, focusing primarily on higher education. With a minimum grant size of $100,000, the foundation prioritizes organizations demonstrating significant impact and sustainability. They support innovative educational models, professional development, and scholarships, specifically targeting underserved populations. Since the 1940s, the foundation has evolved while maintaining its commitment to fostering healthy and productive lives for all individuals in the United States.

The Kidney Health Equity Community Engagement Award by the National Kidney Foundation aims to enhance health equity in kidney care. This award encourages innovative proposals that address disparities in access to kidney care, education, and treatment. With a funding of $75,000 for one year, it supports healthcare professionals and researchers in implementing community-based solutions to improve outcomes for individuals affected by kidney disease. The initiative seeks to dismantle barriers and foster equitable health practices.

The W. R. Grace Foundation Grant supports non-profit organizations with 501(c)(3) status in the U.S. that focus on STEM education and basic needs like food and healthcare. Since its inception in 1961, the Foundation has contributed financial and volunteer resources to enhance community wellbeing, particularly in areas where Grace employees reside. They also match employee donations to accredited educational institutions, promoting civic engagement and support for local charities.

The Michael Hurewitz Scholarship, offered by The Community Foundation for the Greater Capital Region, supports high school seniors in the region who have a passion for journalism and demonstrate financial need. This scholarship aims to empower students by providing them the necessary financial assistance to pursue their educational goals in journalism, fostering the next generation of storytellers and communicators in our community.

The Pittsburgh Foundation Basic Needs Grants for Mental Health aims to enhance access to quality, affordable mental health services for residents, particularly addressing barriers faced by marginalized communities. With funding ranging from $10,000 to $150,000, the program supports initiatives that connect individuals to mental health resources, reduce stigma, and promote social well-being. This grant reflects the Foundation's commitment to improving quality of life and addressing the ongoing impacts of social injustices in Allegheny County.