Best Private Grants for Nonprofits in Pennsylvania

The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.

The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.

The Louis J. Appell, Jr., Preservation Fund for Central Pennsylvania supports local preservation efforts by funding maintenance and restoration of historic places in specific Pennsylvania counties. Eligible applicants include public agencies and non-profit organizations, with a matching requirement for grant amounts. Grants aim to enhance public awareness of the region's heritage while addressing preservation challenges through technical assistance and financial support for essential restoration activities.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.

The Barbara & Maxwell Davison Fund for Alzheimer’s Care, managed by the Lehigh Valley Community Foundation, supports initiatives that provide care and assistance to Alzheimer’s patients in the Lehigh Valley. This area-of-interest fund aims to address critical issues by leveraging community resources and donor contributions to create a significant impact in the lives of those affected by Alzheimer’s. Grants are awarded competitively based on thorough community research.

The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.

The Trails Capacity Program, previously known as the Trail Fund Grant, aims to enhance community capacity for trail maintenance, research, and stewardship training across the nation. The program focuses on supporting non-Forest Service Federal lands, as well as state and local areas, fostering inclusivity and improved user behavior. By collaborating with diverse trail partners, it seeks to ensure effective stewardship and sustainable trail management, ultimately promoting public access and enjoyment of America's natural landscapes.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.

GBA1 Parkinson's Disease Research Catalyst Program

The GBA1-PD Research Catalyst Program seeks to build a deeper, globally integrated understanding of GBA1-associated Parkinson’s disease by aligning efforts across geographies and maximizing the value of shared datasets and research assets. Funding will support hypothesis- driven projects with an emphasis on integrative, cross-cohort analyses and the systematic characterization and standardization of models to enable broad use by the research community.

Funding

Duration: 12 to 24 months

Award Amount: Up to $300,000. Requested support should be commensurate with work proposed.

These budgets include direct and indirect costs. For academic and for-profit institutions, no more than 15% or 10%, respectively, may go to indirect costs. 

The Gilmore | Henne Community Fund, established by NFL players John Gilmore and Chad Henne, offers financial support for park programs and improvements in Berks County, Pennsylvania. Grants of up to $1,000 per park are available, totaling approximately $5,000 in funding. This initiative aims to enhance recreational facilities and positively impact the community and children's lives. Note that funding is not available for pools.

Accelerating the Development of Combined CGM–Pump Devices

A combined continuous glucose monitor (CGM) and insulin pump device represents an innovative approach to simplifying diabetes management by integrating two essential technologies into a single device. This approach has the potential to improve quality of life for people with type 1 diabetes (T1D) by reducing the burden associated with wearing and managing multiple devices.

Despite this promise, the development of combined CGM–pump devices presents technical and commercialization challenges. These include the need for further advances in device compatibility and lifespan, system reliability, and scalable manufacturing, while maintaining affordability and broadaccessibility. In addition, a potential insulin dilution effect may require adjustment of the CGM algorithm.

Breakthrough T1D invites applications for research and development projects that address key technical, clinical, and translational challenges related to combined CGM–pump devices, with the goal of accelerating their development and improving outcomes for people living with T1D.

In response to this announcement, applications may request up to a total of $900,000 USD for up to three years. 

Casey's Cash for Classrooms Grants support K-12 public and nonprofit private schools through funding for physical improvements, material needs, teacher support, and community engagement. In 2025, $900,000 was awarded across 80 grants, allowing schools to enhance their learning environments. With a commitment to community engagement, Casey's has donated $15 million since 2019, emphasizing their dedication to making life better for communities and guests. Grants range from $3,000 to $50,000, with funds required to be used within 12 months.

AD Osherman Scholarship

Benefiting first-generation students in Texas.

Funding

Four (4) scholarships awarded out:

• $3,500 for students pursuing a 4-year degree
• $2,500 for students pursuing a 2-year degree

One-time award. Previous recipients may reapply as long as all eligibility requirements are met.

Camillo Family Scholarship 

Benefiting dependents of Camillo Properties, Camcorp Entities, or LCI Services employees.

The Camillo Family Scholarship was created to provide dependents of employees of Camillo Companies (Camillo Holdings, LCI Services, Legend Homes, Millmark Capital, and SimplyHome) with scholarships to further their education.

This is a renewable scholarship, meaning recipients can renew the award and claim up to 4 years of funding if they meet the GPA and enrollment requirements and complete the renewal application for each academic year they plan to be enrolled.

Multiple scholarships awarded for the 2026-27 academic year. Award amount varies by college/degree type:

• 4-Year College/University - The scholarship is comprised of up to four annual awards of $5,000, for a total award of up to $20,000. The four annual awards may be received over a period of up to five years.
• 2-Year College/Trade School - The scholarship award is comprised of up to two annual awards of $2,500, for a total award of up to $5,000. The two annual awards may be received over a period of up to three years.

What can the scholarship be used for?

The scholarship will be mailed directly to the student's college to be used towards tuition, required academic fees, and/or book expenses. 

Scholarship funding cannot be distributed directly to the student. 

Transportation Assistance Grant

The Transportation Assistance Grant program was established to help members of the MS community remain as independent as possible, and ensure all people with MS have the transportation necessary to get the best medical care.

The program provides funding for reasonable paratransit fees. In partnership with Lyft and Uber, the program can also provide funding for transportation to and from appointments for MS care, limited to neurologist visits and infusion centers, at no cost to the person with MS.

The MNAF Linda Knauff Clinical Practice Project Grant supports Minnesota Nurses Association members in conducting research that aligns with MNA's organizational goals. It promotes best practices through literature reviews, workgroup convening, policy development, and quality improvement initiatives. Applicants must be MNA members engaged in direct patient care, complete their projects within two years, and submit periodic reports. Preference is given to first-time applicants whose projects meet quality standards.

The Bernie Smillie Memorial Scholarship was established in 2010, in memory of Freeland resident and business owner Bernie Smillie. Bernie passed away in 2000, due to complications from a lung transplant he had received in 1994. In 2005, family and friends of Bernie established the Bernie Smillie Memorial Golf Outing. Proceeds of this outing has helped to promote organ donor support and awareness and establish this scholarship fund.

Bernie Smillie Memorial Scholarship - Michigan Resident

Evaluation Criteria

• Financial need (20)
• Work experience (20)
• Overall involvement at work, school and community activities (20)
• Career goals as demonstrated in essay (20)
• Letters of recommendation

The American Journalism Project is dedicated to enhancing local news organizations by investing in their business capacities and providing personalized coaching. They prioritize diversity, equity, and inclusion, encouraging inquiries from organizations serving underrepresented communities. Their approach offers tailored support based on grantees' strategic challenges, fostering sustainable growth in revenue and programming. They seek grantees with strong public-service missions, independent 501(c)(3) status, and a commitment to transparency and accountability in their operations.

The Journalism & Media Grant aims to promote inclusive narratives and accurate media that engage communities in democratic processes. It supports U.S.-based nonprofit organizations focused on professional reporting, multimedia storytelling, and civic media. The grant addresses barriers to media participation and fosters innovation in journalism, providing essential infrastructure for a diverse media landscape. While unsolicited proposals are not accepted, organizations can share ideas through a Letter of Inquiry (LOI).

The Frank M. & Eleanor R. Miese Fund Grant, administered by Bridge Builders Community Foundations, aims to support transformative programs for underprivileged children in Cooperstown and surrounding areas. The foundation promotes growth through philanthropy, ensuring resources enhance community welfare. Eligible organizations must submit a charitable designation. This grant prioritizes projects that positively impact disadvantaged youth, fostering a brighter future through dedicated support and commitment to community development.

Women of Colors Scholarship

Women of Colors (WOC) was founded in 1993 by a group of women that believed it would take a cooperative effort of women of all nationalities, ages and socioeconomic status to address issues plaguing the Saginaw Community. The founders believed that women should take a more active role in addressing issues of crime, blight and poverty. WOC began by providing support, community outreach services and facilitating discussions within the community. WOC’s mission promotes multi-cultural diversity and enhances community relations in Saginaw County by performing community service, mentoring youth, and collaborating with other organizations.

The Women of Colors Scholarship will be awarded each year to a Great Empowering Motivational Sessions (GEMS) member that is an area high school senior actively involved in efforts to empower young women and in activities that address issues affecting young women in the Saginaw Community. If no GEMS members are high school seniors, applications will be accepted from non-GEMS applicants.

Our Littlest Angels – Callie M. Wilson Memorial Scholarship

The “Our Littlest Angels – Callie M. Wilson Memorial Scholarship” was established in 2011 to assist students interested in the field of Nursing.

Callie Wilson was born on December 20, 1981 and was a patient in the Regional Neonatal Intensive Care Unit (RNICU) at Covenant HealthCare in Saginaw. After 46 days of wonderful care, Callie passed away. Her parents, Byron and Mickey Wilson, along with several of their friends started the Our Littlest Angels Fund in 1982. The fund has raised $1.3 million through its golf tournament and bowl-a-thons for the purchase of specialized equipment for the RNICU.

Covenant HealthCare’s RNICU is truly a live saving service for distressed infants throughout the East-Central Region of Michigan. Several thousands of critically ill newborns have been cared for in this unit since its inception.

The golf tournament and bowling event have now been retired and the remaining funds are being used to establish this scholarship to honor all those associated with the RNICU in Callie’s memory. This scholarship will be awarded to students wishing to enter education in nursing. They must demonstrate strong leadership skills and a passion for infants and nursing.

The FY26 Autism Research Program Career Development Award aims to support early-career investigators in conducting innovative research that can significantly impact autism. It encourages applications addressing specific areas of interest and mandates community collaboration for projects involving pilot clinical trials. Proposals must include partnerships with community members for effective planning and implementation, ensuring that the research is grounded in the needs of the autism community.

The FY26 Autism Research Program's Idea Development Award from the US DOD aims to support groundbreaking research that improves outcomes for Autistic individuals. This award encourages innovative, high-risk projects that can lead to significant advancements in autism research. Applications must address specific areas of interest or justify the importance of the research problem. A unique Partnering Principal Investigator option allows two researchers to collaborate on a single project, enhancing the potential for impactful discoveries.

The FY26 Autism Research Program Clinical Trial Award aims to rapidly implement clinical trials that significantly impact autism treatment and management. Projects may range from small proof-of-concept trials to large-scale studies assessing efficacy in relevant populations. Applications are encouraged to partner experienced and early-career investigators and must include community collaborations to enhance research impact. At least one community partner is required to provide ongoing consultation throughout the project.

The Goodridge Brothers Scholarship, offered by the Saginaw Community Foundation, supports residents of Saginaw County pursuing careers in technical education, such as welding or auto mechanics. This initiative recognizes the growing demand for skilled tradespeople and aims to alleviate financial barriers for students. Scholarships typically range from $500 to $4,000, promoting educational opportunities in urban and regional planning and enhancing the community's workforce capabilities.

William L. & Mary Ann Brown STEM Endowment Scholarship Program

The William L. & Mary Ann Brown STEM Endowed Scholarship Program was established by William L. and Mary Ann Brown to provide need-based scholarship support to seniors graduating from a high school in Mecklenburg County, North Carolina, enrolled at a UNCF member institution, four-year HBCUs, and four-year institutions.

Successful applicants must be graduating high school seniors entering their first year of college, pursuing a STEM degree, including, but not limited to, fields in physical sciences, mathematics, the biological sciences, the chemical sciences, computer sciences, and engineering. Applicants must be enrolled or planning to enroll as a full-time student.