Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional) (357744)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
This funding opportunity supports exceptionally promising Early Stage Investigators in genomics, encouraging innovative research across various fields such as genomic sciences and medicine. Applicants must submit their proposals by 5:00 PM local time of their organization. The initiative, led by the US Dept. of Health & Human Services through the NIH, aims to foster long-term career development in genomic research while addressing its ethical, legal, and social implications.
Genetics & Genomics
Medical Ethics
Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.
Infectious & Parasitic Diseases
Addiction & Substance Use Disorders
Drug Use Disorder
Maternal-Child Surveillance and Partnerships for Action, Results, and Knowledge
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The CDC is allocating funds through NOFO DD-27-0028 to enhance maternal child health surveillance and partnerships. This initiative targets public health challenges such as alcohol use during pregnancy and fetal alcohol spectrum disorders (FASDs). It aims to improve clinical surveillance systems, data quality, and timely reporting, while fostering national partnerships to prevent FASDs and support affected infants and children. The approach focuses on translating high-quality surveillance data into actionable prevention strategies.
Children’s Health & Pediatrics
Obstetrics & Neonatal Care
Women's Health
+1 more
Pilot Testing, Implementation, and Evaluation of the Cervical, Breast and Colorectal Cancer Clinical Decision Support Tools
Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The CDC's initiative focuses on developing clinical decision support (CDS) tools for cancer screening and management, specifically for cervical, breast, and colorectal cancers. The project aims to enhance guideline-concordant screening and improve management processes through rigorous implementation and evaluation within large health systems. By integrating these tools into electronic health records, the initiative seeks to support clinicians in making evidence-based decisions at the point of care, ultimately improving patient outcomes in cancer care.
Cancer / Oncology
Dean John A. Knauss Marine Policy Fellowship
Woods Hole Oceanographic Institution (WHOI)
Private
American Samoa, Guam +4 more
Unspecified amount
The Dean John A. Knauss Marine Policy Fellowship offers a unique opportunity for early career professionals to engage in marine and Great Lakes science and policy within the U.S. government. This one-year, paid fellowship encourages graduate students from accredited programs to explore impactful coastal resource issues. Interested applicants should connect with their local Sea Grant program or the National Sea Grant Office for guidance, especially if they are from Massachusetts, to ensure a competitive application.
Marine Biology
Marine / Ocean Conservation
Environmental Policy
+2 more
BRAIN Initiative: Development and Validation of Novel Tools and New Approaches for Neuroscience Research
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.
Neuroscience
Childhood Asthma in Urban Settings Clinical Research Network
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) aims to enhance asthma prevention and treatment in economically disadvantaged pediatric populations. Funded by the NIH, CAUSE supports multi-site clinical studies to identify innovative strategies and treatment targets for asthma. Utilizing systems biology, the network seeks to discover specific disease endotypes suitable for new therapeutic approaches, addressing the high burden of asthma in urban settings.
Respiratory Diseases & Systems
Asthma
Improved Drug Susceptibility Testing (DST) for Mycobacteria
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases
Tuberculosis
Drug-Resistant Bacteria
DOW Combat Readiness – Medical Research Program Translational Research Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,450,000
The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.
Crisis Intervention
Post-Traumatic Stress Disorder
Cooperative Program for Modeling Clinical Transplantation
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Cooperative Program for Modeling Clinical Transplantation, supported by the NIAID, aims to enhance human solid organ transplantation through innovative in-vitro and in-vivo systems. This program encourages applications utilizing new approach methods (NAMs) and refined mouse models to improve clinical translation. Emphasis is placed on developing models that address clinical obstacles and reduce reliance on nonhuman primates, while promoting data sharing to foster reproducibility and best practices in research.
Organ And Tissue Banks
Accelerating Research and Development of Next Generation Malaria Vaccines Against Malaria – A Model for Mosquito-Borne Diseases
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID is focused on advancing the research and development of next-generation malaria vaccines, aiming to leverage innovative vaccine design techniques. This initiative not only aims to enhance malaria prevention but also serves as a model for combating other mosquito-borne diseases. By utilizing cutting-edge methods such as structure-based immunogen design and combination vaccines, the program seeks to significantly reduce both parasite infection rates and the overall disease burden associated with malaria.
Malaria
Tropical Diseases
DoW Amyotrophic Lateral Sclerosis Research Program, Therapeutic Idea Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $840,000
The FY26 Amyotrophic Lateral Sclerosis Research Program Therapeutic Idea Award supports innovative ideas for ALS drug discovery. This award encourages high-risk, high-gain research that is hypothesis-driven and aims to generate preliminary data for future therapeutic investigations. Applications should highlight potential impact and innovation, with the possibility of achieving results without prior data. The focus is on a strong approach rather than preliminary findings.
Amyotrophic Lateral Sclerosis (ALS)
DoW Pancreatic Cancer Research Program, Focused Pilot Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The FY26 DoW Pancreatic Cancer Research Program Focused Pilot Award aims to drive innovative and impactful research in pancreatic cancer, enhancing patient quality of life. This award encourages the development of preliminary data to support future clinical or real-world applications. While allowing for clinical research studies, it does not permit clinical trials or preclinical animal studies, ensuring a strong patient-centered approach in its research focus.
Pancreatic Cancer
DoW Amyotrophic Lateral Sclerosis Research Program, Pilot Clinical Trial Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,800,000
The FY26 Amyotrophic Lateral Sclerosis Research Program's Pilot Clinical Trial Award aims to accelerate clinical trials that can significantly impact ALS treatment and management. Focus areas include biomarker-driven interventions and improvements in clinical care. Trials must begin within 12 months of the award and incorporate community collaboration and a detailed regulatory strategy. This award emphasizes the importance of therapeutic interventions and a transition plan for advancing study outcomes beyond the funded work.
Amyotrophic Lateral Sclerosis (ALS)
DoW Amyotrophic Lateral Sclerosis Research Program, Clinical Outcomes and Biomarkers Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The FY26 Amyotrophic Lateral Sclerosis Research Program (ALSRP) Clinical Outcomes and Biomarkers Award (COBA) aims to enhance clinical trials for ALS by developing and validating clinical outcomes and biomarkers. This funding opportunity encourages innovative projects that may focus on specific therapies, ALS subtypes, or digital health measures. Collaboration with the ALS community is essential to ensure that research is relevant and informed by lived experiences.
Amyotrophic Lateral Sclerosis (ALS)
DoW Breast Cancer, Breakthrough Award Level 4
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $21,000,000
The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 4 supports innovative research with the potential for significant breakthroughs in breast cancer. Applications must address key BCRP challenges or justify exceptions, focusing on impactful solutions. This program mandates clinical trials and requires participation from breast cancer consumer advocates. The funding supports single or partnered Principal Investigators, ensuring comprehensive submission processes to avoid administrative withdrawal.
Breast Cancer
Limited Competition: Small Grant Program for NHLBI Career Development Recipients (Clinical Trial Optional)
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NHLBI is launching a Limited Competition Small Grant Program aimed at NHLBI career development award recipients. This program supports researchers transitioning to independence by providing small grants for expanding research objectives or initiating new studies based on their prior work. It encourages applicants to form collaborations and develop impactful projects, although applications are not currently being solicited. This initiative aims to facilitate the generation of essential preliminary data and publications, aiding recipients in their K-to-R transition.
Workforce Preparation & Job Readiness
Career / College Preparation
The Affirm Cares Employee Foundation Grant
Affirm Cares
Private
American Samoa, Guam +4 more
Unspecified amount
The Affirm Cares Employee Foundation Grant, established by Affirm, aims to support non-profit organizations making a significant impact in financial literacy, community enrichment, and technology education. Grants range from $1,000 to $10,000, focusing on sustainable initiatives that empower communities and alleviate housing insecurity. Eligible applicants must be 501(c)(3) designated non-profits operating within the U.S. The foundation prioritizes measurable outcomes in its funding efforts, fostering civic engagement and vibrant communities.
Homelessness Services
Civic Engagement & Education
Financial Literacy
+5 more
DoW, Ovarian Cancer, Ovarian Cancer Academy – Early-Career Investigator Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The DoW Ovarian Cancer Academy Early-Career Investigator Award supports junior faculty in conducting innovative ovarian cancer research. Established in FY09, this unique virtual academy fosters mentorship, collaboration, and networking among Early-Career Investigators (ECIs) and their mentors. Participants engage in monthly webinars and annual workshops, enhancing their research skills while contributing to impactful studies in ovarian cancer. The program aims to cultivate a new generation of highly productive researchers in this critical field.
Gynecological Cancers
DoW, Ovarian Cancer, Ovarian Cancer Clinical Trial Academy – Early-Career Investigator Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,400,000
The Ovarian Cancer Clinical Trial Academy (OCCTA) supports Early-Career Investigators (ECIs) in clinical trial research aimed at effective ovarian cancer treatments. It provides essential mentoring, networking, and skill development needed for executing clinical trials. The FY26 funding will specifically support translational research and early-phase trials, requiring preliminary data and a commitment of at least 25% effort from the ECI. Mentorship is vital, with a focus on experienced clinical trialists guiding ECIs.
Gynecological Cancers
DoW Ovarian Cancer, Clinical Trial Award
US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,800,000
The DoW Ovarian Cancer Clinical Trial Award, funded by the U.S. Army Medical Command, aims to accelerate the implementation of clinical trials that significantly impact ovarian cancer treatment. This award supports diverse trial designs, from early proof-of-concept studies to large-scale efficacy trials, evaluating innovative drugs, biologics, and technologies. By fostering research in this critical area, the program seeks to enhance patient outcomes and advance the understanding of ovarian cancer management.
Gynecological Cancers
The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC) (360625)
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC) aims to enhance understanding of gastrointestinal disorders by expanding the previous Gastroparesis Consortium's research scope. This initiative will include adult and pediatric conditions linked to impaired interoceptive processing, utilizing multidisciplinary approaches to uncover mechanisms connecting GI function to symptoms, identify biomarkers for treatment efficacy, and explore new therapeutic targets for future clinical trials.
Digestive System Health & Diseases
Medical Technology, Devices, and Equipment
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center aims to enhance understanding of inflammatory bowel disease (IBD) by coordinating extensive genetic research. By leveraging diverse patient cohorts and advanced data science techniques, the center seeks to identify genetic risk factors, develop predictive biomarkers, and improve IBD patient management. This initiative will facilitate collaboration among various research centers and ensure efficient data collection and sharing to foster advancements in precision medicine for IBD.
Digestive System Health & Diseases
Data Science & Digital Information Systems
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genomic Research Centers
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) aims to enhance understanding of inflammatory bowel diseases (IBD) through genomic research. By leveraging patient cohorts and advanced data science, the IBDGC seeks to identify genetic risk factors and develop predictive biomarkers for disease outcomes. This initiative will improve medical management and advance precision medicine for IBD patients, addressing the need for effective diagnostics and treatment strategies in this chronic condition.
Digestive System Health & Diseases
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity from the US Department of Health and Human Services, specifically the National Institutes of Health, aims to examine the effectiveness of family navigation models that divert non-urgent mental health concerns from emergency departments. The initiative seeks to enhance mental health service engagement, provide necessary resources, and support families in overcoming barriers to help-seeking. Key deadlines for applications range from February 2025 to October 2027.
Mental Health & Psychiatric Diseases
Children’s Mental Health
Emergency Medical Care & Services
The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional) (357379)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity aims to advance research on how work impacts health disparities among U.S. populations. It invites innovative proposals that explore the interplay between occupation and health outcomes, particularly in communities experiencing health and healthcare inequalities. Deadlines for applications span from February 2025 to October 2027, encouraging timely submissions for various categories including standard and AIDS-related grants.
Health Disparities & Social Determinants of Health
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) (357458)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.
Cancer / Oncology
Epidemiology & Public Health
Aging / Gerontology
+17 more