Best Grants for Grassroots Organizations in American Samoa

The Engineering Biological and Biomedical Systems (EBBS) program, funded by the National Science Foundation (NSF), aims to advance our understanding of biological systems and improve human health through innovative engineering solutions. It supports research that combines mechanistic insights with experimental techniques to develop novel biomedical technologies, enhance biomanufacturing processes, and explore therapeutic applications. Projects focusing on engineering principles for biological responses and rehabilitation are encouraged, while drug design and clinical trials are outside the program's scope.

The Ocean Technology and Interdisciplinary Coordination (OTIC) Program, funded by the National Science Foundation (NSF), supports innovative research and technology development in ocean science. This program welcomes unsolicited proposals for instrumentation that enhances the capabilities of the ocean research community. It also announces specific funding opportunities aimed at improving facilities and equipment at Biological Field Stations and Marine Laboratories, promoting interdisciplinary collaboration in oceanographic studies.

The Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional) aims to foster unique hub capabilities and research platforms to tackle critical gaps in clinical and translational science. Open to eligible organizations involved in the CTSA Program, this funding opportunity is crucial for laying groundwork for future advancements across CTSA Program Hubs. Applications are due by 5:00 PM local time, with Letters of Intent encouraged 30 days prior to the deadline.

The NSF Expeditions in Computing program aims to foster transformative research in computer and information science. By funding projects up to $15 million over seven years, it encourages multidisciplinary teams to tackle ambitious research agendas that redefine the future of computing. The program supports innovative areas such as new architectures for intelligence, advanced robotics, and next-generation communication, emphasizing the importance of collaboration across various fields to achieve groundbreaking advancements.

The Collaborative Program Grant for Multidisciplinary Teams, funded by the US Dept. of Health & Human Services: National Institutes of Health (NIH), supports integrated teams of researchers tackling ambitious projects that individual efforts cannot achieve. This program promotes collaboration among experts with complementary skills, aiming for significant advancements in their fields. Teams are encouraged to pursue innovative objectives that have the potential to transform research landscapes.

The National Biomedical Research Centers (NBRCs) aim to enhance biomedical research by providing advanced equipment, scientific expertise, and innovative human-based models. Supported by NIH and other federal agencies, this initiative focuses on reducing reliance on live animal models through the development of New Approach Methodologies (NAMs). The program invites applications that propose actionable plans to refine and replace animal use, promoting innovative research at centers with existing nonhuman primate colonies.

The Medical Scientist Training Program (MSTP) aims to cultivate a diverse group of physician-scientist leaders to address the nation's biomedical research needs. This program supports institutions in creating integrated dual-degree training that results in both medical and research doctorate degrees. By combining clinical practice with scientific research, MSTP graduates will advance health-related research, focusing on improving training effectiveness, alumni retention in research careers, and workforce diversity. NIGMS emphasizes comprehensive training elements for impactful careers.

The Medical Scientist Training Program (MSTP) aims to cultivate skilled clinician-scientist leaders to meet the nation's biomedical research demands. It supports domestic organizations in developing dual-degree training that integrates clinical and research education, leading to both a clinical degree (e.g., M.D., D.O.) and a Ph.D. Through comprehensive mentoring and career development, MSTP prepares trainees for impactful careers in health-related research, ensuring a robust pipeline of qualified scientists.

The American Bar Endowment's Opportunity Grant Program provides funding for innovative, boots-on-the-ground initiatives that address urgent legal needs of the public. This grant focuses on increasing access to justice for underserved populations, improving the justice system, and enhancing public understanding of legal rights. Eligible applicants include public charities and organizations directly impacting local communities, with a strong emphasis on projects that leverage technology and address immediate legal challenges.

The HEAL Initiative aims to enhance therapeutic medical devices through team science research, focusing on the mechanisms that drive their effectiveness. The National Institute of Neurological Disorders and Stroke (NINDS) seeks to improve clinical outcomes by fostering interdisciplinary collaborations. This initiative invites teams with expertise in engineering, biology, and clinical care to explore innovative device-based therapies. By understanding how these devices work, the program hopes to optimize existing technologies and inspire new designs, ultimately improving patient care.

The National Science Foundation (NSF) Directorate for Engineering (ENG) fosters groundbreaking research in electrical, communications, and computing systems through programs like Electronic, Photonic, Magnetic, and Quantum Devices (EPMQD) and Circuits and Systems for Communications and Sensing (CSCS). These initiatives emphasize innovative foundational research, particularly in power and energy systems, while being open to transformative ideas without immediate commercial outcomes. Funding availability will shape the portfolios of ECCS awards.

The Advancing Oil and Natural Gas Production and Delivery initiative, led by the United States Department of Energy, seeks innovative proposals that enhance the efficiency and resilience of the oil and gas supply chain. This funding opportunity aims to improve resource utilization, modernize infrastructure, and promote digital transformation. Key objectives include increasing natural gas utilization, reducing economic losses, and optimizing operational costs through advanced technologies and predictive maintenance strategies.

The Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI) by NIGMS aims to enhance research productivity and flexibility for early career scientists. This program consolidates funding into a single award, allowing investigators to pursue ambitious projects while reducing administrative burdens. By supporting diverse research initiatives, MIRA helps cultivate a new generation of innovative researchers, ensuring essential breakthroughs in fundamental science.

The Organizational Change in the Professional Formation of Engineers (ENGINEER:OC) initiative promotes innovative research and activities aimed at transforming engineering education and workforce development. Supported by the National Science Foundation (NSF), it seeks to enhance access to quality engineering programs across diverse institutions. Projects may involve implementing new curricular innovations or adapting existing models to different contexts, ultimately advancing the professional formation of engineers and fostering inclusive educational pathways.

The National Science Foundation (NSF) is funding initiatives to enhance the value of scientific datasets through innovative artificial intelligence (AI) methods. This program aims to facilitate interdisciplinary research and unlock new insights by applying AI for feature extraction, metadata generation, and dataset integration. Proposals should ensure data security and promote collaboration with various sectors to advance AI-driven scientific discovery. By aligning with NSF priorities, researchers can contribute to cutting-edge science and technology for broader participation in STEM.

The Western SARE Local Education and Demonstration Grants aim to promote sustainable agriculture through practical demonstrations and educational activities. This program addresses barriers to adopting sustainable practices by integrating findings from previous research. Projects can last up to three years and receive funding of up to $60,000. Successful proposals involve local demonstrations, trainings, and technical assistance, engaging farmers, ranchers, and agricultural professionals in the process of sustainable agriculture adoption.

The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.

The NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01) invites applications for clinical trials focusing on complementary and integrative health approaches. This funding opportunity emphasizes the importance of multisite feasibility trials to gather essential data for planning future efficacy studies. Deadlines for standard and AIDS-related applications range from February 2024 to November 2026, underscoring the urgency for innovative research in high-priority areas.

Gilead Medical Education Grants fund innovative, data-driven programs that enhance healthcare infrastructure and support vulnerable communities globally. Focused on core therapeutic areas like HIV, liver diseases, and oncology, these grants aim to deliver impactful continuing medical education for healthcare providers. Eligible applicants include for-profit medical education companies and nonprofit organizations. Gilead prioritizes programs that demonstrate a strong capacity to achieve specific educational outcomes, ensuring that support reaches those who need it most.

The BJS FY 2026 Annual Surveys of Probation and Parole (ASPP) from 2026 to 2030 will provide crucial insights into individuals under community supervision in the U.S. By collecting comprehensive data on probation and parole populations, this initiative aims to report accurately on the dynamics and characteristics of correctional supervision. The data collection process will address various challenges, ensuring that the information reflects the realities of both large and small supervising agencies across the country.

The Occupational Safety and Health Education and Research Centers (T42) program, funded by the CDC, focuses on enhancing occupational safety through targeted education and training. By fostering interdisciplinary research and collaboration among academic institutions, this initiative aims to equip professionals with the necessary skills to address workplace health challenges. The program seeks to diversify the workforce and improve worker safety and well-being through outreach and continued education efforts.

The Feasibility Clinical Trials of Mind and Body Interventions grant aims to support trials that examine complementary and integrative health approaches for high-priority NCCIH research topics. This opportunity seeks to gather essential data for designing future efficacy studies, focusing on aspects such as feasibility, acceptability, and recruitment strategies. The goal is to bridge gaps in scientific knowledge and enhance public health impact through rigorous clinical research. Applicants are encouraged to contact NCCIH representatives for guidance.

The NCCIH Multi-Site Feasibility Clinical Trials (R01) invites applications for clinical trials focused on mind and body interventions. This program emphasizes the need for multisite feasibility studies to gather essential data for future efficacy trials. The initiative is designed to enhance public health by addressing gaps in scientific knowledge related to the delivery, recruitment, and data collection of integrative health approaches. Deadlines for submissions range from February 2025 to October 2026.

The FY26 Orthopaedic Research Program Clinical Research Award supports vital clinical research addressing orthopaedic-specific factors and interventions. It aims to generate evidence that optimizes patient outcomes and informs clinical care, benefiting Service Members, Veterans, and the public. Applications should focus on priority areas such as Ligamentous Trauma and Military Women’s Health, ensuring significant impact on patient care and mitigation of orthopaedic injuries.

The U.S. Department of Labor's Bureau of International Labor Affairs has announced $11 million for a cooperative agreement to combat unfair labor practices and Illegal, Unreported, and Unregulated (IUU) fishing in Indonesia and the Philippines. This initiative aims to protect American seafood workers by improving labor enforcement and addressing abusive practices in the global seafood supply chain, ultimately ensuring a fair competitive environment for U.S. businesses and their workers.

The Teiger Foundation's Curatorial Research and Development Grant offers support for innovative curatorial practices within the contemporary visual arts sector. Designed to address gaps in funding, this grant provides up to $50,000 for curatorial research projects, including travel and collaborative investigations. It emphasizes the importance of experimentation and creativity while aligning with values of racial justice and environmental sustainability. The next Call for Proposals will open in Fall 2026, with funding opportunities available to U.S.-based curators.

The Teiger Foundation's Hosting Grant provides up to $75,000 for US-based curators or artistic directors to present contemporary visual art exhibitions that originated in different contexts. This grant encourages resource-sharing and collective learning, allowing institutions to expand their programming sustainably. It prioritizes projects affiliated with established non-profits, fostering community-building and positive change in the field of visual art while addressing issues of racial justice and climate crisis.