Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
This funding opportunity aims to enhance the development of medical products in rare diseases through innovative natural history studies. By generating high-quality data, the FDA seeks to bridge critical knowledge gaps and eliminate barriers in rare disease research. The initiative focuses on diseases with unmet needs, fostering significant impacts for those affected and facilitating the development of effective therapeutic solutions.
Rare Diseases
Manufacturing Engineering
Pharmacology
+1 more
Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T32)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program aims to foster the development of American Indian and Alaska Native scientists by funding eligible Tribal Entities. This initiative focuses on creating effective training and mentoring activities for individuals pursuing doctoral degrees in biomedical research. Ultimately, it seeks to enhance the capability of researchers to address health disparities within AI/AN communities, ensuring culturally appropriate and ethically responsible research practices.
Indigenous Health Systems
Native American Services
Medical Education & Professional Training
+1 more
NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The NIA Expanding Research in AD/ADRD Summer Research Education Program supports the recruitment of early-stage investigators and aims to provide hands-on research experiences in Alzheimer's Disease and related dementias. Targeting high school students, undergraduates, and science teachers, the program enhances STEM education through authentic research opportunities and educational activities. By fostering early exposure to research, it aims to stimulate interest in AD/ADRD careers and address workforce shortages in this critical field.
Dementia & Alzheimer’s Disease
STEM / STEAM Education
Gabby's Dream Scholarship
Muskingum County Community Foundation
Corporate
American Samoa, Guam +4 more
Unspecified amount
Gabby's Dream Scholarship honors the memory of Gabriella Garven, who tragically passed away but chose to be an organ donor, saving five lives. This scholarship aims to support Muskingum County high school seniors pursuing higher education. Applicants must maintain a GPA of 3.5 or higher and demonstrate involvement in extracurricular activities. By providing financial assistance, this scholarship helps students achieve their dreams, reflecting Gabby's spirit of kindness and generosity, and empowering them to make a positive impact in their communities.
Education - Higher Education
Vocational & Trade Education
Academic Scholarship Programs
+1 more
Economic Advancement Grants for Local Empowerment (EAGLE)
US Dept. of Health & Human Services: Administration for Children & Families
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $1,000,000
The Economic Advancement Grants for Local Empowerment (EAGLE) program, funded by the US Department of Health & Human Services, aims to enhance the socioeconomic and cultural vitality of Native communities. It supports initiatives in regenerative agriculture, artificial intelligence, and community resilience. Key goals include fostering Native capacity, sustainable economic growth, and optimizing governance. With a commitment to fully fund these grants for three years, EAGLE promotes innovative solutions tailored to local needs.
Economic Services & Development
Native American Services
Indigenous Services
Systems-Based Approaches to Improve Patient Safety by Improving Healthcare Worker Safety and Well-Being (R01 Clinical Trial Optional)
US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The Systems-Based Approaches to Improve Patient Safety program aims to enhance patient safety by prioritizing healthcare worker safety and well-being. By focusing on systemic improvements, this initiative seeks to create a safer healthcare environment, recognizing that worker safety is integral to patient safety. The funding opportunity encourages innovative proposals that bring new insights from healthcare professionals, ultimately supporting AHRQ's mission to strengthen the patient safety movement.
Patient Care & Services
Occupational Health & Safety
Health Care Access & Delivery
+1 more
Novel Experiential Technologies Assisting Individual Learning (NExT AI) Hubs
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NExT AI Hubs initiative by the NICHD aims to explore innovative applications of AI technologies in enhancing developmental outcomes for children at risk of learning disabilities. This program will focus on high-risk research topics, fostering advancements in understanding how AI can support learning in reading, writing, and mathematics. The initiative is backed by various public health laws, ensuring a comprehensive approach to child health and education.
Children With Disabilities
Learning Disabilities
Artificial Intelligence (AI)
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) (358375)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Intervention Research to Improve Native American Health initiative aims to enhance health outcomes in Native American communities through innovative research. This program supports studies focused on health promotion, disease prevention, and culturally informed treatment strategies. Key deadlines for grant applications are October 21, 2025, and January 7, 2026. By addressing health disparities and leveraging community strengths, the initiative fosters sustainable interventions tailored to specific cultural contexts.
Indigenous Health Systems
Native American Services
Health Disparities & Social Determinants of Health
BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The BRAIN Initiative aims to foster innovation in the development of next-generation devices for recording and modulating the human central nervous system. This funding opportunity encourages clinical studies and translational research to create advanced therapeutic and diagnostic devices for neurological disorders. Applicants are advised to submit Letters of Intent 60 days before the proposal deadline. This initiative emphasizes milestones and collaboration with NIH staff throughout the project.
Neuroscience
Neurological Diseases & Disorders
Medical Technology, Devices, and Equipment
Greatest American Cleanup Grants
Keep America Beautiful (KAB)
Private
United States
Up to US $5,000
The Great American Cleanup Grants, offered by Keep America Beautiful, aim to enhance community beautification and environmental efforts across the U.S. This initiative encourages KAB affiliates to remove litter, plant greenery, and restore public spaces, contributing to the larger goal of cleaning up 25 billion pieces of litter by 2026. With cash grants available, this program fosters collaboration among communities, promoting sustainable practices and a cleaner, greener future for all.
Recycling
Environmental Contamination & Pollution
Waste Management
+5 more
NFF Matching Awards Program- Connecting People to Forests
National Forest Foundation (NFF)
Private
United States
Unspecified amount
The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.
Forestry
Outdoor Recreation
Trail Creation & Maintenance
+3 more
Genomic Community Resources (U24 Clinical Trials Not Allowed)
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Human Genome Research Institute (NHGRI) is launching a Notice of Funding Opportunity (NOFO) aimed at enhancing genomic research through the development and distribution of high-value resources. This initiative encourages collaborative efforts in genomic resource development and the integration of data science in clinical applications. While applications are not currently being accepted, prospective applicants are urged to prepare meaningful collaborations and projects ahead of the formal solicitation.
Cancer / Oncology
Genetics & Genomics
Human Genome & Genetics
Institutional Training Programs to Advance Translational Research on Alzheimer's Disease and AD-Related Dementias (Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to enhance the development of a diverse workforce skilled in translational research related to Alzheimer's disease and related dementias. It supports institutional training programs at both predoctoral and postdoctoral levels, encouraging interdisciplinary approaches integrating data science and clinical research. By fostering knowledge in essential areas such as disease biology and drug discovery, this initiative aims to equip researchers with the skills necessary for impactful contributions in the field.
Dementia & Alzheimer’s Disease
Medical Education & Professional Training
Establishing a Research Network to Guide Foundational Research on Human Consciousness
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The NIH Blueprint for Neuroscience Research Network aims to enhance foundational research on human consciousness, addressing critical biomedical issues such as coma and dementia. By fostering a collaborative framework among 14 NIH institutes, the initiative seeks to improve diagnosis and treatment of neurological disorders through interdisciplinary approaches. Key objectives include detecting consciousness in minimally responsive patients, enhancing understanding of sleep disorders, and exploring new methodologies. This effort will ultimately strengthen U.S. leadership in neuroscience and improve patient outcomes.
Sleep
Dementia & Alzheimer’s Disease
Great Apes and Gibbons Program Grant
Arcus Foundation
Private
Cambodia, Cameroon +18 more
Unspecified amount
The Great Apes and Gibbons Program Grant, administered by the Arcus Foundation, supports conservation efforts for great apes and gibbons across 24 priority landscapes in Africa and Asia. The program emphasizes sustainable coexistence between humans and wildlife, having awarded over 2,000 grants to more than 500 organizations globally. Funding is not available for individuals or specific lobbying activities, ensuring resources are directed towards impactful conservation initiatives.
Primatology
Primate Conservation
Wildlife Rehabilitation & Sanctuaries
Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NHLBI is set to release a NOFO aimed at enhancing an international research platform for cardiac surgery. This initiative will integrate various research areas, including mechanistic science and implementation science, to advance innovative techniques and improve health outcomes for adults with cardiovascular disease. Furthermore, the platform will serve to train future clinical trialists. Potential applicants are encouraged to start forming collaborations and preparing their proposals, as applications are not yet being solicited.
Bioengineering
Pharmacology
Cardiovascular Diseases & Systems
+1 more
ROSS Rapid Response Program
US HUD: Office of Public and Indian Housing (PIH)
Federal Government
American Samoa, Guam +4 more
US $112,500 - US $250,000
The ROSS Rapid Response Program (RRP) by the U.S. Department of Housing and Urban Development (HUD) provides expedited funding to assist communities in addressing urgent social needs. This program offers one-time cost-reimbursable grants for service coordination and direct services, especially in response to emergencies like natural disasters or public health crises. By streamlining the application process, the RRP empowers local leaders to efficiently support residents in HUD-assisted housing, promoting self-sufficiency and resilience.
Basic Human Needs
Equitable & Affordable Housing
Examining the Impact of Artificial Intelligence (AI) on Healthcare Safety (R18)
US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
This grant opportunity from the US Department of Health and Human Services aims to explore the impact of Artificial Intelligence (AI) on healthcare safety. It invites applications to investigate how AI systems can enhance patient safety and improve healthcare delivery. Applicants are encouraged to identify both the benefits of AI technologies and the potential risks to ensure safe implementation. This initiative addresses the need for effective, efficient, and affordable healthcare while safeguarding patient welfare.
Artificial Intelligence (AI)
Patient Safety
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) (352163)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) promotes innovative clinical trials on natural products, such as botanicals and dietary supplements. This funding opportunity supports studies that demonstrate significant scientific rationale and preliminary evidence for efficacy. Applications can explore various delivery methods and combinations with existing treatments to enhance outcomes. Funding is available for up to three years, aimed at bridging basic science discoveries into practical clinical applications.
Integrative & Alternative Health
Drug Safety
Food Safety
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required) (352165)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award supports investigator-initiated clinical trials of natural products, including botanicals and dietary supplements. This funding opportunity aims to validate the pharmacokinetics and bioavailability of these products over three years in a phased approach. Successful trials will provide crucial data for further development and clinical application, emphasizing the importance of scientifically driven research in natural product efficacy.
Food Safety
Drug Safety
Integrative & Alternative Health
Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required) (357303)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites applications for investigator-initiated clinical trials that deliver complementary and integrative health interventions remotely or via mobile health technologies. Emphasizing no in-person contact, the trials should demonstrate feasibility, safety, and potential clinical benefits. A Plan for Enhancing Diverse Perspectives is required for submission, and applicants are encouraged to consult with NCCIH contacts before applying. Deadlines for submissions range from February 2025 to October 2026.
Integrative & Alternative Health
Telemedicine & Telehealth
NIA Postdoctoral Fellowship Award to Promote Broad Participation in Translational Research for AD/ADRD (F32 Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIA Postdoctoral Fellowship Award aims to enhance diversity in the translational research workforce for Alzheimer's disease and related dementias (AD/ADRD). This fellowship supports promising candidates from diverse backgrounds in developing essential translational research skills. The program emphasizes interdisciplinary approaches to treatment, prevention, and early detection of AD/ADRD while providing research experience under the guidance of mentors in clinical trials, fostering a diverse and effective research community.
Dementia & Alzheimer’s Disease
Medical Education & Professional Training
BJA FY 2026 Local Law Enforcement Crime Gun Intelligence Center Integration Initiative
US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $700,000
The BJA FY 2026 Local Law Enforcement Crime Gun Intelligence Center Integration Initiative aims to support law enforcement agencies in establishing and expanding Crime Gun Intelligence Centers (CGICs). This initiative encourages interagency collaboration for the effective management and analysis of crime gun evidence, enhancing the ability to swiftly identify crime guns and their sources. In partnership with the ATF, this program seeks to reduce firearm-related crime and improve prosecution outcomes.
Crime & Justice
Police & Law Enforcement
Gun Violence Prevention
NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) invites applications for mid-phase clinical trials involving natural products like botanicals and dietary supplements. The goal is to advance clinical testing through robust preliminary data, ensuring these products demonstrate measurable impacts on target engagement. Submission deadlines span from March 2024 to October 2026. Applications must focus on optimizing doses and identifying patient responders to inform future efficacy trials, aligning with NCCIH's research priorities.
Food Safety
Drug Safety
Integrative & Alternative Health
Expanding the Therapeutic Pipeline for Treating and Preventing Alzheimer's Disease and Related Dementias: Preclinical Validation and Drug Discovery for Novel Candidate Targets (U01 Clinical Trial Not Allowed)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is set to release a Notice of Funding Opportunity (NOFO) aiming to stimulate research on Alzheimer's disease (AD) and related dementias (ADRD). This initiative focuses on validating novel drug targets and supports early-stage drug discovery efforts. The U01 activity code will be utilized, and while applications are not currently solicited, this notice allows potential applicants ample time to form collaborations and develop impactful projects in the field of AD/ADRD research.
Aging / Gerontology
Dementia & Alzheimer’s Disease
Rooted Pathways Program
First Peoples Fund
Private
American Samoa, Guam +4 more
Up to US $55,000
The Rooted Pathways Program, initiated by First Peoples Fund, offers essential support to Native-led arts organizations, fostering their growth and stability. This funding empowers these organizations to thrive in their missions, providing unrestricted operating support and participation in a Learning Cohort. Eligible applicants include Native nonprofits and collectives with budgets under $500,000, and the program aims to uplift artists from U.S. federally recognized tribes. This initiative is part of the Wallace Foundation's broader commitment to enhancing well-being in the arts.
Artist Training & Development
Community Culture & Heritage
Arts / Culture Access & Participation
+2 more
Service Objects In-Kind Grants
Service Objects
Corporate
United States
Unspecified amount in in-kind support
Service Objects In-Kind Grants support non-profit organizations dedicated to environmental conservation and sustainability. By leveraging their data validation services, they aim to assist projects that promote ecological health and responsible resource management. The program prioritizes applications with clear, measurable objectives and impactful outcomes within one to three years. Organizations with 501(c)(3) status in the U.S. are eligible, while initiatives lacking detailed plans or focusing on generalized education will not qualify. This grant fosters community involvement in environmental stewardship.
Environmental Health
Environmental Conservation
Environmental Education
+3 more