Decentralized Artificial Intelligence through Controlled Emergence (DICE)
US DOD: Advanced Research Projects Agency
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The DICE program, funded by the US DOD's Advanced Research Projects Agency, aims to develop decentralized AI coordination and control algorithms. This initiative focuses on creating a scalable and resilient network of AI agents capable of executing long-term missions in challenging environments while ensuring human oversight. By leveraging principles of self-organization, DICE seeks to enhance the adaptability and predictability of AI behavior, promoting robust outcomes akin to the internet's decentralized architecture.
Military Operations
Artificial Intelligence (AI)
NIAID Research Education Program Advancing the Careers of a Diverse Research Workforce (R25 Clinical Trial Not Allowed) (350855)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,755,000
The NIAID Research Education Program (R25) fosters diverse research careers by supporting educational activities for individuals from underrepresented backgrounds in biomedical sciences. This program encourages skills development, research experiences, and mentoring activities to enhance career trajectories. Key deadlines for grant applications include January 25 and May 25 from 2024 to 2026, with additional deadlines for AIDS-related applications. This initiative aligns with NIH's mission to diversify the research workforce.
Medical Education & Professional Training
STEM / STEAM Education
Biology
+1 more
2027 Quality Samples Program
USDA: Foreign Agricultural Service (FAS)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The 2027 Quality Samples Program, funded by the USDA's Foreign Agricultural Service, aims to enhance U.S. agricultural exports by providing potential foreign importers with samples of high-quality commodities. This initiative seeks to foster better market understanding and appreciation for U.S. products, ultimately promoting greater export opportunities for American producers. By supporting this program, U.S. entities can effectively showcase their agricultural offerings on a global stage.
Agriculture
Agricultural Crops
Agricultural Economics
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional) (350841)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $5,500,000
The Blueprint Neurotherapeutics Network (BPN) invites small businesses to apply for funding to advance small molecule drug discovery and development projects for nervous system disorders. This program supports research through disease-specific assays and partnerships with NIH-funded consultants. Key deadlines for application submissions span from February 2024 to August 2026. BPN ensures institutions retain IP rights for developed drug candidates, facilitating control over patent negotiations.
Neuroscience
Pharmacology
National Estuarine Research Reserve System (NERRS) Land Acquisition and Construction Program for Fiscal Year 2026
National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $3,000,000
The National Estuarine Research Reserve System (NERRS) Land Acquisition and Construction Program for Fiscal Year 2026, funded by NOAA, aims to enhance research and education by supporting land acquisition and construction projects. With approximately $8.5 million available, the program prioritizes strategic expansions of Reserve boundaries and facility enhancements, ensuring sustainable design standards. Funding will support 5-20 projects over 12-36 months, with potential extensions for complex projects, contingent on available funds and negotiations.
Habitat & Ecosystem Restoration
Marine / Ocean Conservation
Freshwater Conservation
+1 more
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.
Dental Health
Pharmacology
Drug Safety
+1 more
Fiscal Year 2026 National Incident Management System (NIMS)
US Department of Homeland Security: Federal Emergency Management Agency (FEMA)
Federal Government
American Samoa, Guam +4 more
Up to US $3,000,000
The Fiscal Year 2026 National Incident Management System (NIMS) Cooperative Agreement aims to enhance the operational capabilities of the Emergency Management Assistance Compact (EMAC) for effective disaster response. It focuses on closing funding gaps, fostering collaboration among federal and non-federal partners, and improving resource coordination during emergencies. This initiative supports the DHS's goals of building national resilience and enhancing first responder training, ensuring swift and effective responses to various threats and disasters.
Domestic / Homeland Security
Disaster Relief / Humanitarian Aid
Disaster Preparedness
Functional Target Validation for Alzheimer's Disease-Related Dementias
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) aims to support innovative research for validating therapeutic targets in Alzheimer's Disease-Related Dementias (ADRD). This initiative focuses on overcoming barriers in treatment development by ensuring well-validated targets linked to disease mechanisms. By employing a phased award mechanism, NINDS seeks to enhance the rigor of target validation, facilitating the transition from basic discoveries to clinical applications, ultimately accelerating the development of effective therapeutic strategies.
Dementia & Alzheimer’s Disease
Exposomic Contributions to ADRD Pathology and Resilience
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) aims to fund research on how environmental factors influence Alzheimer’s disease-related dementias (ADRD). This includes studying toxins, sleep patterns, and stress in relation to ADRD pathology and resilience. Applicants should explore synergistic effects of these factors and their impact on neurobiological mechanisms. Emphasis is placed on lifespan studies and health disparities. Collaboration among experts in exposomics, neuroscience, and community engagement is encouraged to advance understanding in this critical area.
Dementia & Alzheimer’s Disease
Neuroscience
BRAIN Initiative: Data Archives for the BRAIN Initiative
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative aims to create web-accessible data archives to enhance research on brain science by offering tools for data analysis and visualization. This effort, led by the National Institute of Mental Health in collaboration with other NIH Institutes, seeks to establish a framework for rigorous data sharing and collaboration across various sub-domains. The initiative will enable the scientific community to access standardized and comprehensive data archives to support innovative neurotechnology research.
Cell Biology
Neuroscience
Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE, RP1 Clinical Trial Not Allowed)
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Cancer Institute's STRIPE program aims to advance cancer therapy by investigating the effects of radionuclide-emitted radiation. This initiative encourages multidisciplinary research to understand how radiation impacts normal tissues and tumor cells, ultimately improving therapeutic outcomes. By consolidating various funding mechanisms, STRIPE seeks to lower entry barriers for researchers, enhance the scientific foundation of radiopharmaceutical therapy, and foster innovative treatment strategies. Projects can be exploratory or research-focused, with flexible timelines for completion.
Cancer / Oncology
Centers without Walls for mechanisms of neurodegeneration in Alzheimer’s disease-related dementias (ADRD)
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) is launching a collaborative initiative aimed at exploring neurodegenerative mechanisms in Alzheimer’s disease-related dementias (ADRD). This program, termed 'Centers without Walls', encourages interdisciplinary teams to merge diverse expertise, utilizing cutting-edge technologies and clinical insights to uncover novel ADRD pathways. By fostering collaboration and data sharing, the initiative seeks to enhance understanding of ADRD complexities and support the development of innovative therapeutic strategies.
Aging / Gerontology
Dementia & Alzheimer’s Disease
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) (350837)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative aims to develop non-addictive therapeutics for pain management through small molecules and biologics. This funding opportunity supports preclinical optimization, facilitating the transition of promising candidates to clinical trials. Important proposal deadlines span from January 2024 to January 2027, with optional Letters of Intent encouraged 30 days prior. The program emphasizes collaboration with NIH staff to ensure thorough project planning and monitoring, aiming to revolutionize pain treatment while ensuring safety and efficacy.
Chronic / Acute Pain
Pharmacology
Anesthesia and Pain Medicine
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional) (356763)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The NIDCD Early Career Research (ECR) Award (R21) supports new scientists establishing independent research careers in areas related to hearing, balance, smell, taste, voice, speech, or language. This grant encourages innovative projects such as secondary data analysis, small research initiatives, and technology development, aiming to generate preliminary data for future R01 applications. All applications must be submitted by 5:00 PM local time of the applicant organization.
Hearing Disorders & Audiology
Communication Disorders
BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative Research on Behavior at the Organismal Level
National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative's BBQS Program aims to revolutionize the study of brain function by facilitating high-resolution tracking of complex behaviors alongside neural activity. This transformative research opportunity seeks to develop innovative tools for minimally intrusive measurements of various biobehavioral functions while accounting for environmental variables. Emphasizing transdisciplinary collaboration, it focuses on creating new analytical frameworks that model neurobehavioral function as dynamic systems influenced by an organism's surroundings, thereby advancing our understanding of behavior at the organismal level.
Neuroscience
Neurological Diseases & Disorders
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed) (350826)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The National Cancer Institute invites applications for the validation of biomarkers and assays for cancer detection and treatment. This funding opportunity supports both analytical and clinical validation of assays, emphasizing the importance of human samples. The program encourages multi-disciplinary collaboration and aims to enhance the performance and reproducibility of cancer assays across clinical laboratories. Applications are due by 5:00 PM local time during the designated deadlines each year.
Cancer / Oncology
Molecular Biology
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed) (356718)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The National Cancer Institute (NCI) invites applications for the validation of molecular, cellular, and imaging markers for cancer detection and treatment. This funding opportunity supports both analytical and clinical validation phases, emphasizing multi-disciplinary collaboration. The UH2 phase focuses on analytical validation, while the UH3 phase extends to clinical validation using well-annotated biospecimens. Proposals should justify the relevance of assays for clinical use and may include harmonization efforts across laboratories.
Cancer / Oncology
Biomedical Imaging
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed) (356717)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The National Cancer Institute (NCI) seeks to enhance the validation of biomarkers and assays for cancer detection and treatment through its UH3 funding mechanism. This initiative supports multi-disciplinary collaborations to validate existing assays over three years using clinical trial specimens. Emphasis is placed on harmonizing laboratory tests and validating pharmacodynamic markers. Projects should not focus on early-stage technology development but aim for integration into clinical studies as investigational assays.
Cancer / Oncology
Biomedical Imaging
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (Clinical Trial Required)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH is inviting applications for interventions aimed at enhancing cancer screening and preventive services in underserved populations. This initiative focuses on addressing barriers to healthcare access and promoting timely follow-up on abnormal findings. Collaborations with community partners are encouraged to foster effective outreach. The program particularly seeks to engage patients, clinicians, and healthcare settings in improving health equity and outcomes in cancer prevention.
Health Disparities & Social Determinants of Health
Cancer / Oncology
Preventative Healthcare
Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Chemical or Radiation/Nuclear (CRN) Threats
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID is dedicated to advancing research on medical countermeasures against chemical and radiation threats, focusing on innovative technologies to diagnose and treat exposure effects. The initiative promotes the development of models, biomarkers, and devices that enhance survival and reduce morbidity during public health emergencies. It supports preclinical efforts to address injuries from designated Chemicals of Concern, emphasizing the need for effective solutions in civilian mass casualty scenarios.
Chemistry
Biochemistry
Accelerating Research and Development of Next Generation Malaria Vaccines Against Malaria – A Model for Mosquito-Borne Diseases
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID is focused on advancing the research and development of next-generation malaria vaccines, aiming to leverage innovative vaccine design techniques. This initiative not only aims to enhance malaria prevention but also serves as a model for combating other mosquito-borne diseases. By utilizing cutting-edge methods such as structure-based immunogen design and combination vaccines, the program seeks to significantly reduce both parasite infection rates and the overall disease burden associated with malaria.
Malaria
Tropical Diseases
Cooperative Program for Modeling Clinical Transplantation
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Cooperative Program for Modeling Clinical Transplantation, supported by the NIAID, aims to enhance human solid organ transplantation through innovative in-vitro and in-vivo systems. This program encourages applications utilizing new approach methods (NAMs) and refined mouse models to improve clinical translation. Emphasis is placed on developing models that address clinical obstacles and reduce reliance on nonhuman primates, while promoting data sharing to foster reproducibility and best practices in research.
Organ And Tissue Banks
Exploratory Grant Award to Promote Workforce Diversity in Basic Cancer Research (R21 Clinical Trial Not Allowed) (350823)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The Exploratory Grant Award aims to enhance workforce diversity in basic cancer research by supporting junior and Early Stage Investigators from underrepresented groups in the biomedical and social sciences. This initiative provides essential funding to bridge the gap for researchers completing their training, ensuring they have the resources needed to develop larger grant applications. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.
Cancer / Oncology
Diversity, Equity & Inclusion
Medical Education & Professional Training
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR is inviting applications for the continuation or revision of ongoing clinical trials through the UH3 Clinical Trial Required grant. This opportunity supports extensions for completing trials or longer follow-up periods, as well as revisions that are well justified. Key deadlines for submissions are set from March 2025 to January 2028, with optional Letters of Intent encouraged thirty days prior to application due dates. Ensure compliance with the outlined requirements to enhance your chances of funding.
Dental Health
Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Drug Abuse is funding pilot and feasibility studies aimed at preparing for substance use and HIV prevention research trials. The program encourages innovative interventions for substance use disorders and HIV eradication, focusing on stakeholder collaboration and practical application. Projects may include assessment of service models, intervention development, and community engagement. This initiative is designed to fill critical research gaps and enhance partnerships, although applications are not currently being accepted.
Addiction & Substance Use Disorders
HIV / AIDS
Drug Use Disorder
Elucidation and Validation of the role of Transporters in the Placenta, Lactating Mammary Gland, Developing Gut, and Blood Brain Barrier
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH grant focuses on elucidating the role of transporters in key perinatal barriers such as the placenta and blood-brain barrier. By establishing a multi-barrier transport network, the initiative aims to enhance understanding of maternal and infant health regarding nutrient and medication transport. This research will create essential resources and standards, fostering future studies on perinatal exposure and intervention strategies. Ultimately, it aims to advance knowledge in pediatric pharmacology and neurodevelopment.
Children’s Health & Pediatrics
Maternal And Perinatal Health
Protecting the American Seafood Supply Chain by Countering Unfair Labor Practices and Illegal, Unreported, and Unregulated (IUU) Fishing
US Department of Labor: Bureau of International Labor Affairs (ILAB)
Federal Government
American Samoa, Guam +4 more
Up to US $11,000,000
The U.S. Department of Labor's Bureau of International Labor Affairs has announced $11 million for a cooperative agreement to combat unfair labor practices and Illegal, Unreported, and Unregulated (IUU) fishing in Indonesia and the Philippines. This initiative aims to protect American seafood workers by improving labor enforcement and addressing abusive practices in the global seafood supply chain, ultimately ensuring a fair competitive environment for U.S. businesses and their workers.
Workers’ Rights