Best Large Grants for Nonprofit Organizations in Arkansas

The Domtar Community Investment Grant supports nonprofits and charities in areas where the company operates, focusing on education, environmental sustainability, and community humanitarian needs. Eligible organizations include charitable groups, while ineligible entities encompass individuals, discriminatory organizations, and political causes. Applications are accepted online from January 1 to November 30, with reviews conducted bi-monthly. This initiative aims to create meaningful connections between charitable efforts and the social benefits derived from Domtar's business operations.

The Damon Runyon Scholars Program for Advancing Research and Knowledge (SPARK) aims to empower exceptional college seniors and recent graduates to excel in cancer research. This year-long program provides hands-on training in research labs, mentorship from Damon Runyon scientists, and support for graduate school applications. SPARK particularly encourages applicants from underrepresented backgrounds, fostering inclusivity in science and preparing future leaders in the fight against cancer. Through SPARK, young talents gain the skills and networks needed for successful careers in biomedical research.

The National PTA Outstanding Advocacy Awards recognize exemplary efforts by state, local, and individual PTA advocates dedicated to improving the education, health, and well-being of children. Established by the National PTA, these awards highlight four categories of advocacy: Outstanding State PTA Advocacy, Outstanding Local PTA Advocacy, Shirley Igo Advocate of the Year, and Outstanding Youth Advocate of the Year. Awardees will be celebrated at the National PTA’s Legislative Conference in March 2026.

The ROSES 2025: A.17 Hydrosphere program by NASA aims to enhance our understanding of Earth's water systems, focusing on Ocean Physics, Precipitation Science, and Terrestrial Hydrology. This initiative invites proposals targeting specific priorities within these disciplines to advance knowledge on water distribution and movement across the Earth. Proposals will undergo rigorous peer review to ensure transparency and scientific integrity, aligning with NASA's commitment to reproducible and collaborative research.

Alliance for Cancer Gene Therapy

Unlike surgery, chemotherapy and radiation, cell and gene therapies harness the power of your immune system to destroy cancer cells without harming healthy tissue. We fund the research that will make this vision a reality.

Collaborating with partners and funding research fellows, we are transforming cancer treatments today while bringing the world closer to a cure for all cancers tomorrow.

ACGT Investigator Award in Cell and Gene Therapy for SOLID TUMOR CANCERS 

Purpose

Alliance for Cancer Gene Therapy, Inc. (ACGT) funds breakthrough research that is transforming cancer treatment through cell and gene therapy. This ACGT grant award is for those conducting translational cell and gene therapy research specifically in solid tumor cancers.

Research Objectives

Cell and gene therapy for solid tumors poses major challenges driven by antigen heterogeneity, physical exclusion, immunosuppressive microenvironments, genomic instability, and safety limitations. This RFA seeks innovative, translational cell and gene therapy strategies that directly address these barriers.

Proposed approaches should demonstrate the capacity to: (1) overcome antigen escape through multi-targeted designs that broaden patient populations and account for heterogeneity and resistance due to antigen loss; (2) enhance trafficking, infiltration, and persistence within solid tumor sites; (3) resist or reprogram the immunosuppressive tumor microenvironment; and (4) incorporate built-in safety and controllability mechanisms suitable for clinical translation. Successful proposals will integrate these elements to enable durable, precise, and scalable therapeutic impact in solid tumors.

Building on the priorities outlined above, this RFP encourages proposals spanning a broad range of cell and gene therapy (CGT) platforms and rational combinations, including but not limited to:

• Engineered T Cell Approaches
• Innate and Alternative Immune Cell Platforms
• Gene Editing & Synthetic Biology Strategies
• Microenvironment-Modulating Strategies
• Combinatorial Approaches

Proposals that integrate multiple strategies to overcome trafficking, suppression, antigen escape, and safety barriers in a coordinated manner are strongly encouraged. Preference will be given to approaches with clear mechanistic rationale and a credible path toward clinical translation in solid tumors.

The XENO PRIZE for Artists’ Books offers a $5000 grant to support the publication of an artist's book addressing the themes of book banning and burning. Open to independent artists in the U.S., the prize will be awarded based on submissions to be accepted starting March 1, 2025. A minimum of 100 copies must be printed, with winners announced in September 2025. This initiative aims to highlight and preserve avant-garde art forms and their cultural significance.

The Kretler Scholarship offers up to $1,000 to high school seniors from selected schools in Noble County pursuing degrees in Tool and Die or Mechanical Engineering. This scholarship aims to support students in achieving their educational goals, reflecting the commitment of its donors to invest in local talent. Eligible candidates must maintain a GPA of 3.00 and can reapply in subsequent years, fostering continued academic success in their chosen fields.

The Michigan Health Endowment Fund offers Scholarships for Conferences and Professional Development to support health-related events. These scholarships, up to $2,500 per person and $5,000 per organization, are available for current or past grantees and partners. Applications are accepted on a rolling basis, with a requirement to submit at least four weeks before the event. Priority is given to organizations that haven't received funding in the previous year, ensuring equitable access to professional development opportunities.

The Park Foundation Grants for Civic Participation aim to enhance democracy through active civic engagement. Focused on mobilizing voters and protecting their rights, this program supports grassroots organizations addressing social injustices. By fostering year-round involvement rather than just election-focused efforts, the foundation seeks to empower communities and ensure robust participation in the democratic process, ultimately contributing to a more equitable society.

The Small Business Transition Grant for New Entrepreneurs supports new investigators transitioning into entrepreneurship, particularly in small business settings. This NIH initiative aims to bolster their development as Program Directors or Principal Investigators while fostering their research and entrepreneurial skills. By promoting training and mentorship, this grant encourages the growth of promising technologies that align with NIH's mission to enhance health and save lives. Applications are due by 5 PM local time, with optional Letters of Intent recommended 30 days prior.

The EDA FY25 Disaster Supplemental program provides critical funding to support communities recovering from severe economic distress caused by natural disasters in 2023 and 2024. With no submission deadlines for Readiness and Implementation Paths, and a specific deadline for Industry Transformation applications, this initiative aims to enhance community resilience and improve economic trajectories through strategic projects that engage local stakeholders and private industries.

The Graduate Education Fund offers scholarships for American and Australian graduate students to study in each other's countries. With deadlines in March and September, eligible applicants can receive up to $40,000 to support their education in fields like Science and Technology. This initiative fosters cross-cultural academic collaboration and requires applicants to be enrolled in accredited programs, ensuring a high standard of educational exchange.

The Vilcek Foundation's 2026 Prizes for Creative Promise in Fashion & Design and Fashion & Culture will award six $50,000 prizes to young immigrant professionals. This initiative recognizes early- and mid-career creatives in fields such as fashion design, writing, and styling, highlighting the vital contributions of immigrants to the arts in the U.S. Eligible applicants must have at least five years of experience and intend to pursue their careers in the country.

A better world, built with better teamwork

We bring Atlassian's funding, tools and teamwork expertise to help nonprofits drive greater impact.

Our mission

Atlassian's mission is to unleash the potential of every team. The Atlassian Foundation extends that mission to teams solving the world's hardest problems.

Atlassian Foundation – Open Call for Proposals

The Atlassian Foundation is deploying US$8 million over the next two years to help disadvantaged learners thrive in the AI era. If you're driving collective action in this space, we want to hear from you.

Reshaping education for the AI era will take teamwork

The Atlassian Foundation focuses on education because it's the most empowering force in the world – it's the key to breaking cycles of poverty and disadvantage.

But that key is slipping out of reach for far too many. UNESCO estimates that more than 250 million children are out of school. And for those in the classroom, learning isn't guaranteed: 57% of children worldwide (nearly one billion) lack the basic skills they need for the era they're growing up in. AI can expand access and accelerate learning. It can also widen inequality where it lands unevenly.

No single organisation can tackle a challenge this complex. That's why the Atlassian Foundation is backing collective action: coordinated efforts by multiple players to solve shared problems at scale. Atlassian's mission is to unleash the potential of every team, so we're uniquely positioned to power these efforts. We've spent 20+ years learning what makes teams work well together, and we're offering that expertise – plus our funding, tools and hands-on support – to help collective action initiatives drive greater impact.

We believe a better world is built with better teamwork, and collective action is teamwork at its most ambitious. Together, we want to shape a future where emerging technology closes gaps for learners the current system leaves behind, rather than widening them.

About this open call

In this open call, we're seeking partnerships with collective action initiatives that are working to improve education for disadvantaged learners in the AI era.

What our partners will receive

Each partnership will include:

Beatrice T. And Virgil D. Gutierrez Legacy Scholarship

The Beatrice T. Gutierrez and Virgil D. Gutierrez Legacy Scholarship was established in 2018 by the children of Beatrice and Virgil Gutierrez. Mr. and Mrs. Gutierrez devoted their lives to teaching in Taos Public Schools.

The scholarship will be available to seniors graduating from High Schools in Taos County, with a preference to those students who intend to pursue studies in mathematics, education or science (including but not limited to social, biological and environmental sciences) by attending a 4 year college or university with an overall goal of providing service to their family and/or community upon graduation. The 4 year institution award is up to $14,000, paid out across 4 years if a 3.0 GPA is maintained.

The scholarship will also be available to seniors graduating from High Schools in Taos County, with a preference to those students who intend to pursue a 2-year vocational program with an overall goal of providing service to their family and/or community upon graduation. The 2 year institution award is up to $4,000, paid out across 2 years.

The Edna and Erma Memorial Scholarship, established by The Dayton Foundation in 2018, supports women from Montgomery County, Ohio, pursuing education degrees. It is aimed at female high school seniors and adult learners returning to college, requiring a minimum GPA of 3.0 and demonstrated financial need. This scholarship reflects the Foundation's commitment to enhancing educational opportunities and empowering women in the community.

The Damon Runyon Physician-Scientist Training Award aims to address the shortage of physician-scientists by supporting U.S. Specialty Board eligible physicians in cancer research. This award provides funding for up to four years, enabling awardees to dedicate 80% of their time to research while maintaining clinical skills. The program seeks to eliminate financial barriers, allowing talented clinicians to transform into leading researchers capable of advancing cancer treatment and prevention.

The Learning Engineering Tools Competition is a significant funding opportunity aimed at fostering educational technology innovations. It seeks to leverage digital tools, big data, and learning science to improve learner outcomes globally. This competition encourages diverse participants, from students to established companies, to develop solutions that can generate valuable learning data. By promoting collaboration among educators, researchers, and tech innovators, the initiative aims to advance the field of learning engineering and enhance educational practices.

About AWS

We Move Welding Forward

Founded in 1919, the American Welding Society is a nonprofit organization with a global mission: to advance the science, technology, and application of welding and allied joining and cutting processes worldwide, including brazing, soldering, and thermal spraying.

By fostering knowledge, embracing change, and providing real-world opportunities through scholarships, fellowships, and workforce development, AWS provides the tools to help members succeed—and to inspire future generations of welding professionals.

Welding Educator Professional Development Scholarships

AWS Foundation Welding Educator Professional Development Scholarships provide funding for welding educators to advance their skills and impact in teaching. Aimed at current educators in welding-related fields, these scholarships demonstrate AWS's dedication to enriching welding education.

District Educator Scholarships

Each of AWS’s 22 Districts awards educator scholarships worth $500 to $2,000.

To see which District your school is in, view the AWS District and Section Directory.

Funds are paid directly to the educational institution or organization providing the training.

The AWS Educator Professional Development Scholarships are awarded annually in May or June.

Holcomb Family Education Scholarship

This scholarship was established in 2008 by the Hall County Optimist Club to honor long-time educators, J.H. Holcomb and his sisters, Margaret, Mildred, and Nell. Applicants must have demonstrated financial need and have a minimum 3.0 GPA. In 2026, one scholarship award of $1,000 will be offered.

The Prioritization Process Pilot Program (PPPP) Competitive Grant Program, funded by the DOT Federal Highway Administration, offers up to $26 million for innovative transportation planning in FYs 2024-2026. Grants of up to $2 million will support the development of transparent, data-driven prioritization processes for project selection in transportation plans, ensuring that funded projects deliver public benefits and meet community needs.

The GCA: Catherine H. Beattie Fellowship in Conservation Horticulture, provided by the Garden Club of America, offers an annual research grant of up to $4,500 for graduate students in biology or horticulture. This fellowship aims to promote the conservation of rare and endangered flora in the U.S., particularly focusing on the southeastern region. Eligible applicants must be U.S. citizens or permanent residents enrolled in a U.S.-based institution, with preference given to those studying plants native to the Carolinas.

About AWS

We Move Welding Forward

Founded in 1919, the American Welding Society is a nonprofit organization with a global mission: to advance the science, technology, and application of welding and allied joining and cutting processes worldwide, including brazing, soldering, and thermal spraying.

By fostering knowledge, embracing change, and providing real-world opportunities through scholarships, fellowships, and workforce development, AWS provides the tools to help members succeed—and to inspire future generations of welding professionals.

Welding Educator Professional Development Scholarships

AWS Foundation Welding Educator Professional Development Scholarships provide funding for welding educators to advance their skills and impact in teaching. Aimed at current educators in welding-related fields, these scholarships demonstrate AWS's dedication to enriching welding education.

National Educator Scholarships

Five donor-funded scholarships worth $1,000 to $5,000

• Bechtel Group Foundation Educator Scholarship
• Earl C. Lipphardt Educator Scholarship
• Jackson Safety Educator Scholarship
• Tim Turner Educator Scholarship
• William Kielhorn Educator Scholarship

Funds are paid directly to the educational institution or organization providing the training.

The AWS Educator Professional Development Scholarships are awarded annually in May or June.

Mission

The Social Science Research Council (SSRC) is an independent, international, nonprofit organization founded in 1923. The Council fosters innovative research, nurtures new generations of social scientists, deepens how inquiry is practiced within and across disciplines, and mobilizes necessary knowledge on important public issues.

SSRC-JF Next Gen Japan Study Tour Grants

The SSRC-JF Next Generation Japan Studies Development Program invites faculty at US colleges and universities to apply for funding of up to $32,500 maximum for institutional study tour grants. These grants are designed to provide travel funds to bring undergraduate and master’s degree students to Japan for immersive learning experiences. This program is supported by the Japan Foundation.

Background

At the core of the Next Gen Japan programming is the idea that international experience, research engagement, and collaboration are central to effectively addressing the pressing concerns facing societies today. Japan Study Tour Grants offer students the opportunity to gain a nuanced and balanced understanding of Japan while sparking an enduring interest in the country and a broader, international perspective.

Prioritie

Priority will be given to the following applications:

• Applications from the liberal arts colleges, research universities, and community colleges located in the US South and Midwest.
• Applications with travel itineraries appropriately planned to enhance the course syllabus.
• Applications with travel itineraries highlighting close collaboration with Japanese counterparts.
• Applications that demonstrate the study tour would be open to students from a variety of disciplines ranging from the humanities and social sciences to the natural sciences.

NASA Internships

Background

NASA has developed a single, one-stop Agency system for the recruitment, application, selection and career development of undergraduate and graduate students in science, technology, engineering and mathematics disciplines. Students access information about internship and fellowship opportunities across NASA to engage in research, aerospace education and space exploration. A student completes a single internship and/or fellowship application to express interest in up to 15 specific opportunities for each summer, fall, spring or year-long session.

Objectives

NASA Internships are competitive awards to support educational opportunities that provide unique NASA-related research and operational experiences for high school, undergraduate, and graduate students, as well as educators. These opportunities serve students by integrating interns with career professionals emphasizing mentor-directed, degree-related tasks, while contributing to the operation of a NASA facility or the advancement of NASA’s missions.

Award Level

Levels may vary per opportunity.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Thomas William Bennett Memorial Scholarship Fund

He believed that a person could do anything if they sat down and read how to do it. When WWII started, he was the first man from the state of South Carolina to enlist in the U.S. Army. He quickly rose to captain and spent most of the war in the Pacific (the Queen of Fiji considered him a friend). Later, Thomas had a long career at Harcourt Brace publishing.

Stark Community Foundation

Since 1963, Stark Community Foundation has been helping individuals, families, businesses and nonprofits like you support the causes you care about.

In addition to personalized donor services, we manage a competitive grantmaking program and award grants to address local needs. Today, the Foundation stewards over 1,000 charitable funds totaling $485 million in assets and has granted more than $300 million to nonprofits in our community and beyond.

Scholarships

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties.

The Ken Finney Memorial Scholarship Fund

The Ken Finney Memorial Scholarship Fund assists students seeking a bachelor’s in mechanical engineering or music who are residents of Stark, Wayne or Carroll counties (or adjacent counties).

This scholarship is renewable.