Best Large Grants for Nonprofit Organizations in Arkansas

Nonprofit 501(c)(3) and 509(a)(1)/(2) organizations, primarily in the greater Chicago area, can seek McGraw Foundation grants of US $2,000 - US $10,000 for education, human services, health, conservation, and cultural programs. Arkansas nonprofits with relevant programming may be eligible for single-year operating, project, or occasional capital support.

Graduate students conducting research in drinking water quality, environmental science, or public health can receive US $3,000 to advance projects with timely, actionable outcomes for the water industry. Focused on water-related research, the American Water Works Association opportunity may benefit Arkansas-based academic programs or nonprofit partners supporting eligible students.

Nonprofit 501(c)(3) organizations in Arkansas seeking support for economic and workforce advancement, affordable housing, or community arts and culture may be eligible for this funding. Grants from US Bancorp Foundation help organizations in designated U.S. Bank communities that advance diversity, equity, and inclusion, especially those led by people of color and addressing multiple Work, Home, and Play pillars.

Arkansas 501(c)(3) public charities offering safety, workforce development, community vitality, or environmental sustainability programs can access funding through Union Pacific Foundation’s Community Ties Local Grants. Awards of US $5,000 - US $30,000 support direct services and capacity-building in Union Pacific–served communities, with emphasis on DEI and broad, positive social impact.

Nonprofit organizations, schools, and government entities serving Weyerhaeuser communities in Arkansas can seek grants of more than US $1,000 for housing, youth development, environmental stewardship, human services, and related community needs. Weyerhaeuser Giving Fund supports local, high-impact projects in these focus areas across its designated Arkansas counties.

Nonprofit organizations in Arkansas supporting women and children through self-sufficiency, humanitarian aid, or child welfare programs can access funding via The Father's Table Foundation. Grants up to US $750,000 may support efforts like homelessness services, job readiness, education, food security, microfinance, health care, anti-trafficking, and disaster relief that build long-term resilience.

NIH provides Arkansas undergraduate-focused higher education institutions with funding for small-scale biomedical research projects. Eligible colleges and universities must award baccalaureate science degrees and have limited prior NIH support; grants up to Up to US $375,000 can enhance research environments and offer hands-on experience in areas like public health, neuroscience, genetics, HIV/AIDS, and more.

Arkansas 501(c)(3) nonprofits focused on economic opportunity or affordable housing can access funding through Bank of America Charitable Foundation to build organizational capacity and leadership. Selected “Neighborhood Builders” join a two-year leadership development program while receiving support for initiatives like workforce readiness, small business resilience, financial literacy, or equitable and affordable housing services.

Nonprofit 501(c)(3) organizations serving Arkansas residents can seek $15,000 - $75,000 for community programs benefiting seniors, children and youth, low-income residents, education, and nonprofit capacity. Focused on human services and education, the Carl B. and Florence E. King Foundation supports project-based work rather than general operating expenses in eligible Arkansas counties.

Early-career research scientists at academic or research institutions in low- or middle-income countries, including those with Arkansas partnerships, can apply for the Emerging Global Leader Award to support independent clinical trial research. Grants from the National Institutes of Health provide approximately US $140,000 plus protected time over three to five years for mentored career development.

Early-career research scientists at academic or research institutions in eligible low- or middle-income countries can apply for National Institutes of Health Emerging Global Leader Awards, with approximately US $140,000 for mentored health research and career development. Arkansas-based nonprofits partnering with LMIC investigators on global health projects may be able to collaborate under this program.

Nonprofit 501(c)(3) organizations seeking funding for education-focused programs, youth initiatives, arts and culture, community services, or related efforts in the U.S., including Arkansas, may be eligible for this grant. John Ben Snow Memorial Trust awards US $5,000 - US $20,000, with a preference for new or enhanced programs and short-term, one-time support.

Arkansas nonprofits, institutions, and similar organizations can seek sponsorship funding for medical and scientific congresses, events, or initiatives that offer Biogen Foundation tangible benefits like recognition or marketing opportunities. Biogen considers a wide range of neurological and related disease areas, and evaluates requests based on funding availability, topic alignment, event details, and event location.

Nonprofit 501(c) or 170(c) organizations in Arkansas working on community development, education, financial wellness, arts and culture, veterans, or disability services can receive matching donations through Regions Bank’s retiree program, with awards up to US $1,000. Eligible gifts must come from recent Regions retirees and meet the program’s mission-focused criteria.

Nonprofit 501(c) or 170(c) organizations in Arkansas working on economic development, education, financial wellness, arts, veterans, or disability services can benefit from Regions Bank’s employee Matching Gifts Program. Eligible charities receive matched donations from full-time associates and recent retirees, helping strengthen community programs within the Regions footprint, with accredited educational institutions eligible nationwide.

Nonprofit 501(c)(3) organizations, or those with a fiscal sponsor, can seek general operating support for grassroots work in regenerative agriculture, healthy food access, climate justice, and pollution-free environments in Arkansas and nationwide. Focused on these priorities, Clif Family Foundation offers US $5,000 - US $50,000 one-year grants, with applications reviewed twice annually.

Nonprofit and conservation organizations in Arkansas that provide technical assistance to private landowners for regenerative agriculture and habitat conservation can seek US $250,000 - US $750,000 through the Conservation Partners Grant Program. National Fish and Wildlife Foundation supports projects that help landowners plan, implement best practices, engage in Farm Bill programs, and share conservation lessons learned.

Free and charitable clinics in Arkansas that are NAFC members can apply for the NAFC Healthcare Services Expansion Fund, awarding US $30,000 - US $50,000 for launching or expanding clinical programs. Funding can support areas like behavioral health, women’s health, telehealth, chronic disease management, mobile clinics, and other patient-centered services for underserved communities.

Students pursuing natural resource–related degrees in Arkansas can receive scholarship support for full-time study in fields like ecology, forestry, hydrology, or environmental education. With a mission to support higher education in conservation-related disciplines, Community Foundation of Northern Illinois offers this aid to residents of select northeastern Illinois counties attending accredited two- or four-year institutions.

The OECD Conference Sponsorship aims to enhance scientific knowledge and provide essential information to influence policy decisions on sustainable resource use in food, agriculture, forestry, and fisheries. It supports international events that showcase innovative research and developments, inviting applications from scientists in these fields. The event sponsorship encourages collaboration among policymakers, industry, and academia, ensuring that research insights are effectively communicated and utilized in decision-making processes.

The RNRF Planning and Small Grants program provides funding up to $50,000 to support projects that enhance collaboration among community partners in addressing critical environmental issues. Eligible applicants must be 501c3 organizations in the U.S. and demonstrate multidisciplinary cooperation. Projects should align with RNRF's mission and focus areas, including air quality, biodiversity, and renewable energy. The initiative aims to create sustainable and impactful outcomes by bridging research and practical implementation.

The RNRF Rapid Response Grants provide essential funding up to $50,000 for projects adversely affected by the loss of federal support. The program aims to foster collaboration among organizations working towards sustainable environmental, social, and economic practices. Eligible applicants must be 501(c)(3) organizations in the U.S. and demonstrate multidisciplinary collaboration with RNRF member organizations, ensuring impactful outcomes in critical focus areas such as air quality, biodiversity conservation, and renewable energy.

The RNRF Implementation/Collaboration Grants support innovative projects that enhance collaboration among stakeholders to address critical challenges in environmental, social, and economic systems. Offering up to $200,000 for initiatives lasting 12 months or more, these grants aim to implement evidence-based practices and facilitate multidisciplinary teamwork. Eligible applicants must be from 501c3 organizations in the U.S., ensuring alignment with RNRF's mission and focus areas, fostering sustainable and impactful outcomes.

RBC Foundation – USA aims to enhance community quality of life by supporting non-profit organizations that promote diversity and positive change. In 2023, it awarded over $2.8 million in grants, prioritizing youth programs for ages 15-29, arts access for diverse populations, and mental well-being initiatives. The foundation encourages sustainable projects that foster economic independence, providing critical support for education, mental health, and cultural enrichment, thereby making a significant impact across various communities.

The Siletz Tribal Charitable Contribution Fund, established by the Confederated Tribes of Siletz Indians, has distributed over $16.3 million in grants since 1999. It supports charitable organizations and local governments in eleven Oregon counties, as well as Native American initiatives across the U.S. The fund prioritizes education, health, public safety, addiction prevention, housing, arts, and environmental preservation, ensuring the Tribe's commitment to community support and cultural heritage.

The Regional Conservation Partnership Program (RCPP) Classic for FY 2026 encourages collaboration between the NRCS and partners to address critical natural resource concerns through innovative projects. By co-investing with partners, the program aims to enhance conservation efforts on farms and private lands, ensuring equitable access to NRCS services. Selected proposals will be based on their potential impact and effective partnership management, ultimately improving environmental outcomes across designated Critical Conservation Areas.

Sanofi Philanthropic Donations support non-profit organizations aligned with Health Equity, STEM Education Equity, and Local Communities. Applications are accepted year-round, with a review process of 8 to 16 weeks. The initiative focuses on improving healthcare access, fostering innovation, and addressing social determinants of health. Sanofi emphasizes collaboration and sustainable solutions, advocating for equal opportunities in health and education, and nurturing future talent to tackle medical challenges.