Best Large Grants for Nonprofit Organizations in Arkansas

Homecare Assistance Grant

MS Focus understands the daily needs and challenges that must be met by both those with MS and their caregivers. In order to meet these needs in the most timely and efficient way possible, our Homecare Assistance Grant connects you to the best available local services. Should resources within your community not be available, direct support may be provided on a temporary basis.

Available Services include:

• Home Care - Personal hygiene services, light housekeeping, grocery shopping, meal preparation, and transportation to and from appointments are all services that can be provided for a limited time.
• Therapy Visits - Based upon individual need, an appointment with an occupational, physical, or speech therapist can be arranged. Through education and training, these therapists can help to foster independence, self-esteem, and better quality of life for the person living with MS.
• Respite Care - Respite allows primary caregivers the opportunity to tend to themselves, or other family business, with the assurance that their loved one is being cared for by a properly trained individual. This service is provided on a short-term basis for a scheduled period of time. 
• Coming Home - Returning home from a stay at the hospital can be a difficult time of transition. We offer a four-hour visit from an aide who will meet the patient at the hospital, provide transportation home, and then get the patient settled comfortably at home.

The Charles B. Decker Memorial Scholarship, established in 1991, supports college and graduate students from the Tri-Lakes area pursuing journalism careers. This scholarship emphasizes the importance of education in the Adirondack region by providing essential financial assistance to students dedicated to journalism. Candidates are evaluated based on financial need, demonstrated commitment to journalism, and academic achievements, ensuring that the scholarship aligns with the foundation's mission to invest in educational opportunities.

The BJA FY 2026 Tribal Justice Training and Technical Assistance Program aims to enhance Tribal justice systems through specialized technical support. This funding opportunity addresses critical issues such as violent crime and substance-use related crime, including opioids. By assisting federally recognized Indian Tribes, the program promotes the development of sustainable legal and corrections infrastructure while fostering collaboration with federal, state, and local partners. Applications are due by October 28, 2026, at 8:59 p.m. ET.

The Heiser Program for Research in Leprosy, established by Dr. Victor G. Heiser, focuses on innovative biomedical research to combat leprosy. Since 1975, it has funded over 200 grants totaling more than $20 million, supporting early-career researchers and significant projects. The program aims to enhance diagnostic tools, improve treatments, and implement effective surveillance strategies. With a dedicated Scientific Advisory Committee, it ensures rigorous proposal reviews and fosters collaboration among grantees, ultimately advancing leprosy elimination efforts.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing Type 1 diabetes research by exploring the innate immune system's role in disease onset. This initiative aims to identify genetic and environmental factors contributing to Type 1 diabetes through multidisciplinary teams. By employing innovative methodologies, the program seeks to determine how immune responses affect pancreatic tissues, potentially leading to early detection and prevention strategies for at-risk individuals.

The Hot Springs Area Community Foundation offers Early Literacy Grants to enhance early childhood language and literacy skills. With funding between $2,500 and $10,000 for the 2025–2026 period, the program prioritizes initiatives that connect children from birth to age four with literacy resources. Special emphasis is placed on proposals that expand phonics instruction and engage parents and communities in early learning, continuing the mission to prepare young learners for academic success.

The PLTW Engineering Program Expansion grant, funded by Project Lead The Way Inc, offers $10,000 to public schools in specific districts across several states, including Arkansas, Georgia, and Virginia. This grant aims to enhance existing PLTW Engineering courses or add new ones, alongside teacher training for the 2025-2026 academic year. Grantees are required to submit annual reports and assist in collecting surveys to aid in program improvement and stakeholder engagement.

The Richard S. Reynolds Foundation, established in 1955 in Richmond, Virginia, supports diverse community initiatives in education, healthcare, the arts, and the environment. With over $71 million granted to date, it aims to strengthen communities and foster future generations. The foundation prioritizes requests from IRS-recognized 501(c)(3) organizations while typically avoiding contributions to annual operational costs. Its commitment to impactful projects ensures a lasting positive influence both locally and globally.

About BlackRock

We’re a global asset manager and technology provider dedicated to helping more and more people experience financial well-being. We help millions of people invest to build savings that serve them throughout their lives. The BlackRock Foundation which funds and partners with organizations that strengthen financial security for more people,

BlackRock Future Builders

BlackRock Future Builders is a $100 million philanthropic initiative funded by The BlackRock Foundation to expand economic opportunity and power the next generation of America’s skilled trades workers. Through this Request for Proposals (RFP) process, The Foundation seeks to support U.S. nonprofit organizations (i.e., registered 501(c)3 organizations) delivering or supporting high‑quality skilled trades training.

This competitive grant opportunity operates in parallel to other BlackRock Future Builders partnerships and is intended to surface additional, regionally grounded solutions across the skilled trades ecosystem. Organizations may propose direct worker training programs or capacity‑building efforts that enable systems to function more effectively and at greater scale. This first round RFP will be administered by Jobs for the Future (JFF), a national nonprofit that transforms U.S. education and workforce systems.

Focus Areas and Solutions

Applicants may propose worker training or capacity‑building solutions aligned to skilled trades workforce development.

• Worker training interventions may include direct service proposals such as pre-apprenticeship or career navigation programs, workforce training programs, apprenticeship programs, or wraparound participant supports that are supportive of training persistence and completion.
• Capacity-building interventions are organizational and system-focused, rather than in direct service of participants, and may include, but are not limited to, proposals such as ecosystem-building, demonstration projects, technology or tool adoptions, or research, among others.

Melton Foundation

The Melton Foundation is an international 501(c)(3) non-profit organization registered in the USA, and a leading proponent of Global Citizenship education and practice worldwide. Established nearly thirty years ago with the credence that collaborations across boundaries can forge sustainable solutions to the world’s most pressing challenges, today, our programs reach millions of young leaders, having crystallized into a network of over 750 life-long Melton Fellows spread across 40+ countries. Our primary operations are in Chile, China, Germany, Ghana, India, and the United States of America, with legal subsidiaries in Bangalore, India; Jena, Germany; Temuco, Chile; and Accra, Ghana. 

Through our fellowship and collaborative programs we promote and enable global citizenship as a way for individuals and organizations to work together across boundaries of place and identity to solve challenges in an interconnected world.

Melton Foundation Action Grants

The Melton Foundation offers grants year-round to support Melton Fellows in developing skills, perspective and wider networks to further their capacity as global citizens and contribute towards building an equitable, sustainable, and peaceful world.

In almost 10 years of granting, more than 100 Fellows’ initiatives have been awarded with a Melton Foundation grant to

• Build awareness and/or further awareness raising around global issues and the Sustainable Development Goals (SDGs),
• Develop individual and collective responsibility for sustained, collaborative action,
• Grow capacity to collaboratively drive and sustain social impact at the local and/or global level,
• Further the design, implementation and evaluation of collaborative actions that embody the spirit of global citizenship practice and further social impact, or
• Support coordinated social-impact efforts in a particular or across (emerging) Melton Foundation Hub regions to promote global citizenship practice (s) and the organization’s mission.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Daniel R. Miller (Fretts) Memorial Scholarship Fund

The Daniel R. Miller (Fretts) Memorial Scholarship Fund was established to provide scholarship assistance for vocational and higher educational opportunities for Scottdale Borough/East Huntingdon Twp. youth. The fund was endowed by Daniel R. (Bob) Miller’s daughter Karen to honor the memory of her father and the Miller & Fretts families of the Scottdale Area. Bob Miller, for whom this scholarship is named, was born and raised in Scottdale. He believed that the core values instilled in him by his immediate Miller and Fretts relatives in the Scottdale area were a contributing factor to his later successful business career and other lifetime experiences.

The purpose of the scholarship is to provide scholarship assistance to a graduating senior from Southmoreland High School who wishes to pursue a career in a traditional trade or modern equivalent (engineering, architecture, design etc.).

Award Type: Single Year Award. Previous recipients are encouraged to re-apply.

The Ai2 Predoctoral Young Investigators Program offers predoctoral candidates a unique opportunity to engage in advanced research through collaboration with experienced mentors. Participants can co-author papers and benefit from a generous travel budget, along with support for visa acquisition. This program is designed for candidates preparing to enter a PhD program in the next 1-2 years, providing essential resources and experiences to facilitate their academic journey.

Helen Frankenthaler Foundation

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Frankenthaler Climate Initiative

The Frankenthaler Climate Initiative (FCI) is a pioneering grantmaking program established by the Helen Frankenthaler Foundation. Since its inception in 2021, FCI has distinguished itself as the foremost private national initiative in the United States dedicated to combating climate change specifically within the visual arts sector.

FCI provides visual arts institutions with up to $100,000 to undertake ambitious sustainability and energy efficiency initiatives that directly address carbon reduction and energy efficiency. The scope of its support is broad, encompassing everything from modest, rapid-response projects to comprehensive efficiency audits and feasibility studies, and extending to financial contributions for significant infrastructural renovations and strategic planning for new buildings and major initiatives.

Building on the core values of the Helen Frankenthaler Foundation, the initiative aligns a commitment to environmental stewardship with a belief in the vital importance of the visual arts and arts education. Through strategic funding and partnerships focused on tangible infrastructure, FCI aims to catalyze a sector-wide shift toward zero carbon operations, promoting a future where the visual arts thrive—while contributing to a more sustainable and ecologically conscious world.

Who We Fund

FCI funds nonprofit institutions in the United States and its territories whose primary focus rests in the visual arts. The visual arts includes but is not limited to painting, drawing, sculpture, printmaking, photography, and installations in clay, glass, metal, wood, fiber, paper, film, and mixed media.

Most of our grantees are art museums, nonprofit galleries, archives, noncollecting institutions, art schools, university museums, and artist-endowed foundations.

What We Fund

FCI funds energy efficiency and clean energy generation projects.

FCI meets arts institutions at every stage of the work, through four kinds of grants:

• Catalyst — first actions and stand-alone projects with a quick turnaround
• Scoping — energy audits and assessments that establish a baseline
• Technical Assistance — detailed planning for technically demanding projects
• Implementation — comprehensive capital work addressing a building's environmental impact at multiple levels

Technical Assistance Grants

Technical Assistance grants support projects that have finished initial assessments, and need procurement and financing support for an identified efficiency project. This may include providing designs, specifications, or fees for working with energy services companies (ESCOs) for project support. These grants also support more complex studies or analysis required for pursuing major implementation projects. At the conclusion of a Technical Assistance grant, the applicant should be sufficiently informed to implement a project.

AGC Education and Research Foundation

Thanks to visionary volunteer leadership of AGC industry leaders, the AGC Education and Research Foundation, founded in 1968, has for 50 years made good on its commitment to support the future of our industry through its robust scholarship program and innovative projects.

Workforce Development Scholarship

In 2015, the National Center for Construction Education and Research (NCCER) and its Build Your Future initiative made a generous contribution to help fund the first Workforce Development scholarships for students pursuing craft and technical programs, allowing 19 applicants to receive the inaugural scholarships. Scholarships are $1,000 per year, renewable for up to two years.

This is the application for the Workforce Development Scholarship. This scholarship is for students pursuing associate degrees, technical training or certificates to enter the construction industry. Please review the Criteria Page to ensure you qualify for the Workforce Development Scholarship. Scholarships are $1,000 per year, renewable for up to two years. If you are attending a four year university and intend to earn a Bachelor's degree please make sure to apply for our Undergraduate Scholarship application.

The SHAPE America Major of the Year Award recognizes exemplary undergraduate students in health, physical education, recreation, and dance. This prestigious accolade aims to highlight nominees who demonstrate academic excellence and commitment to service within their communities. Faculty members from colleges and universities are encouraged to nominate one outstanding student per major, ensuring that the next generation of health educators is celebrated for their achievements and contributions to the field.

The Ray and Sue Barrett Scholarship, offered by the Grand Haven Area Community Foundation, supports high school seniors in the Tri-Cities pursuing higher education in law, criminal justice, mental health, social work, or psychology. Established in honor of Ray and Sue Barrett, who valued education and mental health, this scholarship considers financial need and requires a minimum 2.5 GPA. Applicants must submit transcripts and relevant documents to qualify.

This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.

The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.

The AAO-HNSF Percy Memorial Research Award offers $25,000 for one year to support innovative research projects in otolaryngology-head and neck surgery. This grant aims to fund projects with clinical significance, encouraging the development of new long-term research initiatives. Applicants must submit a detailed budget and secure letters of support from their Department Chair and key personnel involved in the project. Funds cannot cover salaries or purchase equipment exceeding $500.

The Cyrus M. Quigley Foundation Grant supports tax-exempt organizations that empower young people through initiatives focusing on courage, self-reliance, and service. Since its inception in 1993, the foundation has awarded over $300,000 in grants, with amounts ranging from $1,000 to $7,500. The foundation emphasizes physical challenges and community service to help develop essential life skills. Grant proposals are accepted annually until the third Friday in April, with decisions communicated by May 31.

The EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows program, funded by the National Science Foundation (NSF), aims to enhance research capacity and workforce development in STEM. This initiative fosters collaborations between underrepresented researchers and leading institutions, providing essential resources and support. With two tracks available—one focusing on NSF and the other on NASA—this program uniquely positions Fellows to leverage transformative research experiences and contribute to sustainable advancements in their respective fields.

The OneAmerica Financial Community grant supports 501(c)(3) organizations focused on education, workforce development, safety, wellness, and community vibrancy. With a commitment to making a difference, OneAmerica aims to transform lives through strategic philanthropy. Their initiatives include disaster relief, arts support, and civic engagement, fostering resilient communities. By investing in meaningful change, they build a foundation for shared success across the country, ensuring that community needs are met and future generations thrive.

The Tribal Solar Accelerator Fund (TSAF) empowers tribal communities across the U.S. by promoting renewable energy projects and workforce development. Launched by GRID Alternatives, TSAF provides critical funding for solar initiatives, enhancing energy sovereignty and resilience. Since its inception, TSAF has integrated community participation into its projects, ensuring that tribes can access sustainable energy solutions. By prioritizing education and equity, TSAF supports a transition to a clean energy economy, aiming for a sustainable future for generations to come.

The AES Hawaiʻi Foundation Grant supports communities near AES Hawaiʻi’s renewable energy projects, focusing on social justice, education, environmental stewardship, and community health. Preference is given to nonprofit organizations in these areas, but statewide entities may also apply. Successful projects should align with the Foundation’s impact pillars, demonstrate measurable community benefits, and address unmet needs, ensuring long-term positive effects on the local community.

The ALA Spectrum Scholarship Program offers a one-time $5,000 scholarship to support diverse students pursuing graduate education in library and information studies. Recipients must enroll in an accredited program by fall, receiving funds in two installments. This initiative, supported by the American Library Association, enhances opportunities for over 800 past scholars through mentoring, networking, and professional development, fostering leadership within the library profession across North America.

The Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs) program invites applications to enhance communication and collaboration among researchers in digestive and liver diseases. Funded by the NIDDK, DDRCCs focus on shared resources that foster productivity and innovative research ideas. Each center must revolve around a central theme aligned with the NIDDK's mission, ensuring effective research support while avoiding overlap with other NIH Institutes' funding areas.

The Environmental Grantmaking Program at the Educational Foundation of America (EFA) aims to support projects that facilitate a transition to a net-zero electricity system. Focused on reducing greenhouse gas emissions, the program emphasizes initiatives that enhance access to affordable clean energy, accelerate regional transitions, and strengthen financial investment in electric utilities. Eligible applicants include 501(c)3 public charities, academic institutions, and government entities committed to sustainable energy solutions.