Best Grants for Cancer Nonprofits in Illinois

Nonprofit and other public or private organizations in Illinois can apply for Illinois Department of Public Health’s Carolyn Adams Ticket for the Cure grants, awarding up to US $300,000 for breast cancer patient navigation and related services. Cancer-focused groups, especially those serving high-mortality counties like Cook, DuPage, Kane, Kankakee, Peoria, and St. Clair, may benefit.

Nonprofit 501(c) organizations in Illinois addressing health equity through nutrition, healthcare access, cancer care, STEM education, or environmental health programs can apply for the Community Solutions Challenge, with awards up to US $30,000. Grants from Astrazeneca Foundation help community-based programs serving historically excluded populations, including cancer-focused initiatives and related health disparities work.

Nonprofit organizations in the greater Chicago metropolitan area working on cancer care or research, education for the underprivileged, or related Catholic charitable activities can seek support through the Guy A. and N. Kay Arboit Charitable Trust. First American Bank administers this trust, which may benefit Illinois cancer nonprofits serving under-resourced communities.

Childhood Cancer Research

The grant purpose is to fund one awardee or a research project conducted by Illinois researchers on childhood cancer. The grant award must be used to research childhood cancers or expand current childhood cancer research that must be completed by June 30, 2027. Topics may include, but are not limited to, epidemiology, etiology, pathology, social or economic impacts, in-home care, and psychosocial issues. This is a one-year grant award.

The Mathers Charitable Foundation Grant focuses on advancing basic scientific research with the potential to transform human health. It supports institutions and investigators in fields such as immunology, cancer biology, and neuroscience while prioritizing impactful, foundational discoveries. The foundation empowers researchers to drive innovative solutions and foster meaningful contributions to science and society. Eligibility includes U.S.-based institutions and principal investigators with equipped labs, while ineligible entities include overseas institutions and private foundations.

The 2026 Radiation Oncology Institute- Innovation Awards aim to advance cancer treatment by integrating radiation therapy with immunotherapy. Researchers are invited to submit proposals that explore optimal combinations of these modalities to enhance patient outcomes. Funding of up to $100,000 over two years will support projects focused on identifying effective treatment strategies, understanding mechanisms of synergy, and improving access to care. This initiative represents a significant opportunity for innovative research in oncology.

The Radiation Oncology Institute (ROI) Innovation Awards, offered by the American Society for Radiation Oncology, aim to accelerate innovative ideas in radiation therapy. Currently accepting applications for the 2026 awards, the program focuses on optimizing the combination of radiation therapy and immunotherapy to enhance cancer treatment outcomes. By supporting practical research, ROI strives to transform clinical practices and improve patient care in the fight against cancer.

Pfizer is offering a grant opportunity for independent medical education initiatives focused on Muscle Invasive Bladder Cancer (MIBC). This program aims to address the current knowledge gaps among healthcare professionals regarding emerging treatment data and its potential impact on clinical practices. By collaborating with Astellas, Pfizer seeks proposals that enhance awareness and understanding of the evolving MIBC landscape, ultimately improving patient outcomes in this critical area of unmet medical need.

The Joyce Bytof Memorial Cancer Survivors Scholarship, established by Joyce Bytof in collaboration with the American Cancer Society, supports childhood cancer survivors graduating from specific Wisconsin high schools. This scholarship aims to assist them in pursuing higher education despite the financial and academic challenges posed by their experiences. Joyce's legacy continues to inspire hope and resilience among young survivors as they strive for academic success and a brighter future.

The AACR-Torrey Coast Foundation Transpacific Gastric and Esophageal Cancer Research Partnership Grant supports innovative research on upper gastrointestinal malignancies, which are responsible for over one million deaths globally in 2023. This grant encourages collaboration between U.S. and Asian institutions, focusing on resistance, metastasis, and novel treatment strategies. Proposals should detail plans for clinical translation and are open to researchers at all career stages, especially those new to upper GI cancer research.

Bristol Myers Squibb Foundation Inc supports independent medical education to enhance healthcare professional competence and improve patient health outcomes. Their mission is to be a global leader in innovative medical education, focusing on evidence-based activities that address critical gaps in knowledge. By fostering excellence in healthcare, they aim to ensure measurable improvements in performance and patient outcomes across various disease areas.

The National Cancer Institute (NCI) invites applications for the validation of biomarkers and assays for cancer detection and treatment. This funding opportunity allows for biphasic or monophasic applications to support both analytical and clinical validation phases. Successful projects will leverage human specimens to develop assays that enhance cancer treatment and prevention, ensuring multidisciplinary collaboration among scientists and clinicians. This initiative aims to improve cancer management through reliable and clinically validated tools.

The American Heart Association is seeking proposals to study the prevalence and treatment of cardiovascular, kidney, and metabolic diseases among cancer patients and survivors. Given the over 16.7 million cancer survivors in the U.S., this research aims to highlight critical health disparities, identify treatment modalities, and explore shared risk factors. Applications focusing on underrepresented populations and utilizing real-world data sources are especially encouraged, aiming to improve health outcomes in this vulnerable group.

The ASCO Clinical Oncology & Research Experience (ASCO CORE) offers medical students immersive exposure to the field of oncology through shadowing experiences in clinical and research settings. With two distinct tracks, participants can gain insights into patient care or research practices, guided by mentors. Eligible students must be enrolled in a U.S. DO or MD program and maintain a good academic record. This program aims to inspire the next generation of oncology professionals.

Grants Program for Penn Investigators - Faculty Awards

Research grant applications in basic science, prevention, disease interception, and early detection that are relevant to the study of BRCA1/2 will be considered. The Basser Cancer Interception Institute focuses on funding new endeavors in emerging, orthogonal fields beyond DNA damage (e.g. mechanisms of haploinsufficiency, cancer evolution and tissue tropism). 

Grants focused on the following are of particular interest:

• Cancer interception and the pre-cancer disease state
• Issues relevant to men (including but not limited to prostate cancer, pancreatic cancer, male breast cancer)
• Potential for translation into clinical practice
• Early detection

Grants that demonstrate a potential for translation into clinical practice will be prioritized for funding.

Faculty Awards

Faculty awards are for two years with a funding level up to $200,000 per year.

Grants Program for Penn Investigators - Early career awards for Fellows, Postdocs and Instructors

Research grant applications in basic science, prevention, disease interception, and early detection that are relevant to the study of BRCA1/2 will be considered. The Basser Cancer Interception Institute focuses on funding new endeavors in emerging, orthogonal fields beyond DNA damage (e.g. mechanisms of haploinsufficiency, cancer evolution and tissue tropism). 

Grants focused on the following are of particular interest:

• Cancer interception and the pre-cancer disease state
• Issues relevant to men (including but not limited to prostate cancer, pancreatic cancer, male breast cancer)
• Potential for translation into clinical practice
• Early detection

Grants that demonstrate a potential for translation into clinical practice will be prioritized for funding.

Early career awards for Fellows, Postdocs and Instructors

Early career awards for Fellows, Postdocs and Instructors up to $100,000 for one year. Grants are eligible for competitive renewal upon reapplication and are contingent on progress the first year.

The CORE Funding: AHNS Presidential Award supports innovative research that integrates emerging technologies in head and neck cancer studies. This initiative aims to address critical gaps in early detection and treatment, especially for patients with advanced disease. By leveraging tools such as AI and advanced imaging, the program seeks to enhance understanding of disease mechanisms and improve patient-centered intervention strategies, ultimately advancing the field of otolaryngology.

The CORE Funding: AHNS Thyroid Cancer Survivors’ Association Award aims to support vital research projects focused on thyroid cancer, encompassing prevention, diagnosis, treatment, and outcomes. This initiative by the American Academy of Otolaryngology - Head and Neck Surgery Foundation promotes advancements in the field through funding opportunities that enhance research capabilities and foster collaboration among researchers. Through the support of this award, significant strides can be made in understanding and combating thyroid cancer.

The CORE Funding: AHNS Trainee Pilot Research Award supports innovative research in head and neck oncology, encouraging trainees to engage in clinical or translational studies. Since its inception, CORE has provided over $14 million in grants, facilitating significant advancements in otolaryngology. This initiative aims to enhance research efforts, reduce fragmentation, and promote collaboration among various stakeholders to improve outcomes for patients with head and neck neoplastic diseases.

The CORE Funding: Lilly Research Grant aims to advance research on genetic hearing loss. It invites investigators to explore the genetic factors contributing to hearing loss, promoting innovative projects that enhance understanding in this critical area. Supported by the American Academy of Otolaryngology - Head & Neck Surgery Foundation, the grant fosters significant research efforts to improve outcomes and strategies in otolaryngology, ensuring a comprehensive approach to hearing health.

About Pfizer External Research & Grants

Pfizer External Research & Grants (ER&G) supports independent research, education, and QI initiatives to improve patient outcomes in areas of unmet need. Competitive grants are awarded through transparent RFPs reviewed by independent expert panels.

About ASCP

American Society for Clinical Pathology (ASCP) is the world’s largest professional membership organization for pathologists and laboratory professionals, with more than 100,000 members. ASCP provides excellence in education, certification, and advocacy on behalf of patients and the laboratory workforce. With a portfolio of more than 900 educational activities, ASCP is the worldwide leader in providing CME/CMLE credit for the entire laboratory team.

Quality Improvement in Molecular Testing Pathways for Metastatic Colorectal Cancer (mCRC)

The American Society for Clinical Pathology (ASCP), in collaboration with Pfizer Inc. and with participation from the American Society of Clinical Oncology (ASCO, invites proposals for pathology-centric Quality Improvement (QI) initiatives aimed at optimizing molecular testing pathways in the management of metastatic colorectal cancer (mCRC). This grant opportunity seeks to fund sustainable projects that improve biomarker testing practices, strengthen targeted therapy selection, and support care teams in implementing patient-centered protocols. 

The overarching goal of this program is to advance diagnostic excellence and improve treatment decision-making for patients with mCRC.

The American Academy of Otolaryngology–Head and Neck Surgery Foundation is inviting proposals for the CORE Funding: AHNS Presidential Award, aimed at enhancing value-based care in head and neck oncology. This initiative focuses on improving quality, efficiency, and patient outcomes through data-driven strategies. Key proposal components include quality and process measures, along with identifying care gaps. Priority areas include behavioral health integration and innovative contracting models, promoting scalable solutions that enhance care quality and value in this specialty.

National Collegiate Cancer Foundation

The National Collegiate Cancer Foundation (NCCF) is a national 501(c)(3) nonprofit organization dedicated to supporting young adults diagnosed with or impacted by cancer. Its mission is to provide services, resources, and need-based financial assistance that empower survivors and their families to adopt a resilient “Will Win” mindset throughout treatment and beyond. NCCF is one of the few national organizations that provides direct financial support to young adult cancer survivors, primarily through its Survivor and Legacy Scholarships, which assist students pursuing higher education during or after treatment. The Foundation also promotes cancer awareness and prevention within the young adult community. Recognizing that adolescents and young adults (ages 15–39) face unique challenges—including delayed diagnoses, limited access to insurance and clinical trials, fertility concerns, employment disruption, and social isolation—NCCF prioritizes addressing the significant service gaps affecting this underserved population. Operated entirely by volunteers, NCCF remains committed to advancing educational access, financial relief, and hope for young adult cancer survivors nationwide.

NCCF: Legacy Scholarship Program

The National Collegiate Cancer Foundation (NCCF) offers $1,000 competitive scholarships to young adults pursuing higher education who have lost a parent or guardian to cancer. The award is designed to provide financial assistance and encouragement to students continuing their education despite personal loss. Applications are evaluated based on the applicant’s personal journey, sources of encouragement, demonstrated financial need, notable accomplishments, and the quality of recommendations. The scholarship recognizes resilience, perseverance, and academic commitment in the face of cancer-related loss.

The National Human Genome Research Institute (NHGRI) is launching a Notice of Funding Opportunity (NOFO) aimed at enhancing genomic research through the development and distribution of high-value resources. This initiative encourages collaborative efforts in genomic resource development and the integration of data science in clinical applications. While applications are not currently being accepted, prospective applicants are urged to prepare meaningful collaborations and projects ahead of the formal solicitation.

Funding Innovative Research

Cannonball Kids’ cancer Foundation (CKc) prioritizes funding clinical trials, research that is nearing translation to a clinical trial, and young investigator grants.

Grants funded by CKc must be innovative and provide better quality of life or symptom relief than current treatments. 

When possible, CKc will prioritize funding research:

• with a focus on cancers that are under-funded or under-researched,
• with a focus on patient populations who are traditionally underserved.

When possible, CKc will prioritize funding researchers of diverse backgrounds.

For CKc, “innovation” means the invention or application of novel methods or treatments, specifically treatments that have fewer side-effects than standard care, increase a child’s quality of life, and/or create an option for care where there otherwise were few or none (either on primary diagnosis, relapse, or for recalcitrant cancers).

Research Grants

Grant Program: Clinical Trial

$200,000 over 3 years

• PI must hold an academic appointment at the Assistant Professor level or higher
• Preclinical studies must be complete
• If an FDA Investigational New Drug (IND) application is necessary for the proposed clinical study, the IND application should already have passed FDA initial review and be active
• If the PI has recruited additional patient enrollment sites, local IRB approval must be obtained for each site.

• How many treatment options would this study provide for children?
• How accessible is this study for children and families to access?

Funding Innovative Research

Cannonball Kids’ cancer Foundation (CKc) prioritizes funding clinical trials, research that is nearing translation to a clinical trial, and young investigator grants.

Grants funded by CKc must be innovative and provide better quality of life or symptom relief than current treatments. 

When possible, CKc will prioritize funding research:

• with a focus on cancers that are under-funded or under-researched,
• with a focus on patient populations who are traditionally underserved.

When possible, CKc will prioritize funding researchers of diverse backgrounds.

For CKc, “innovation” means the invention or application of novel methods or treatments, specifically treatments that have fewer side-effects than standard care, increase a child’s quality of life, and/or create an option for care where there otherwise were few or none (either on primary diagnosis, relapse, or for recalcitrant cancers).

Research Grants

Grant Program: Young Investigator

$100,000 over 3 years

• PI must hold an academic appointment at the instructor level or higher
• PI must be within 5 years of completing a training fellowship in Pediatric Hematology/Oncology or a closely related discipline that has direct clinical contact with pediatric cancer patients
• Research must be within 2-3 years to translation to a clinical trial or already associated with a clinical trial

• Evidence of Mentor's commitment to the PI's career development plan
• Translational potential

The National Cancer Institute's PAIRS program aims to explore innovative cancer therapies by leveraging synthetic vulnerabilities that interact with tumor responses to radiation therapy. This initiative supports the development of targeted drug-radiation combinations, focusing on precision medicine to optimize treatment efficacy while minimizing harm to normal tissues. By consolidating prior funding opportunities, PAIRS encourages research that addresses context-dependent vulnerabilities, enhancing therapeutic strategies and aligning with NIH's scientific goals.