Best Unrestricted Grants for Nonprofits in Colorado

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33) invites research proposals for early phase clinical trials of natural products, including botanicals and dietary supplements, emphasizing scientific validity for further testing. Applicants may receive up to three years of funding for pharmacokinetics and bioavailability studies, with potential for an additional three years to evaluate clinical outcomes. This initiative aims to optimize natural product delivery through innovative study designs.

The Beth N. Rom-Rymer Travel Scholarship provides $1,000 for Native psychology graduate students to attend the American Psychological Association's annual convention. This opportunity is specifically for members of the Society of Indian Psychologists (SIP). The scholarship aims to support diverse applicants and encourages first-time attendees who demonstrate financial need. APF, the funding organization, is dedicated to enhancing the field of psychology by supporting early career professionals and their contributions to societal improvement.

HCLTech Grant Edition II focuses on impactful climate action by investing $5 million over five years to support NGOs in the Americas. This initiative aims to enhance sustainable projects that align with the 17 Sustainable Development Goals (SDGs). With a history of significant contributions in India, HCLTech is committed to achieving net-zero emissions by 2040 and fostering innovative solutions to address pressing climate challenges. The grant encourages collaboration and aims to transform communities through effective climate action.

The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.

The AWS Welding Workforce Grants aim to enhance welding programs by providing up to $50,000 for essential resources such as new equipment and training. This initiative addresses the growing demand for skilled welders while supporting educational institutions. Eligible applicants include secondary schools, community colleges, and post-secondary programs. Preference is given to proposals that significantly increase welding graduates and address geographic areas with high needs. Note: Applications are currently closed and will reopen in January 2026.

The Dalsemer Interstitial Lung Disease Award, funded by the American Lung Association, provides $50,000 per year for two years to support junior investigators researching interstitial lung disease. This award aims to foster independence in early-career scientists while building on the Association's 120-year legacy of improving lung health through innovative research and advocacy efforts, ultimately enhancing the lives of those affected by lung disease.

The NASPGHAN Foundation/APGNN Susan Moyer Research Grant supports impactful research and quality improvement initiatives aimed at enhancing nursing care for children with gastrointestinal and nutritional disorders. Grants ranging from $500 to $5000 are available for eligible Registered Nurses who are APGNN members. Awardees must present their findings at the NASPGHAN Annual Meeting and adhere to specific funding guidelines, including IRB approval and acknowledgment of support in publications.

The Hasting Innovation Award for Interstitial Lung Disease, offered by the American Lung Association, provides $75,000 annually for up to two years to support early-career researchers. This award targets investigators with proven excellence and a track record of accomplishment, aiming to advance lung disease science. Successful candidates must have held a K or R type award within the last three to five years, fostering innovation and discovery in lung health.

The Lung Cancer Discovery Award, offered by the American Lung Association, supports innovative research aimed at improving outcomes for lung cancer patients. With funding of $100,000 per year for up to two years, this award encourages groundbreaking projects that enhance diagnostic and therapeutic strategies, investigate genetic forms of lung cancer, and develop novel screening methods. The initiative is a vital step towards reducing lung cancer morbidity and mortality, ultimately improving patient care and saving lives.

The Medical Student Mentored Summer Research Program offers medical students in the U.S. and Canada a unique opportunity to engage in a 10-week research experience under expert mentorship in pediatric gastroenterology, hepatology, or nutrition. With a stipend of $4000 paid in installments, this program is designed for students who have completed at least their first year of medical training. Preference is given to those seeking research experience between their first and second years.

The American Epilepsy Society offers Predoctoral Research Fellowships to support students conducting epilepsy-related dissertation research under expert mentorship. Proposals in basic, translational, or clinical research are encouraged. Each fellowship provides up to $30,000 for stipend and travel to the AES Annual Meeting for one year, along with a one-year AES membership. The number of awards varies annually based on available funding.

The American Epilepsy Society offers Postdoctoral Research Fellowships to support trainees conducting research on epilepsy's causes, treatment, and consequences. These fellowships provide up to $49,000 for stipend and benefits, $1,000 for travel to the AES annual meeting, and complimentary membership. Proposals can be basic, translational, or clinical research, and the number of awards depends on available funding.

The NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) aims to support innovative research in behavioral and social interventions for dental, oral, and craniofacial conditions. This funding opportunity includes a milestone-driven planning phase of up to 2 years, with potential transition to implementation for an additional 5 years, facilitating comprehensive trial development and assessment.

The Donald & Ruby Branson Foundation Grant aims to promote environmental, educational, and social progress in America. Established by the Branson family, it seeks to instill values of community involvement and charitable responsibility in future generations. The foundation primarily supports tax-exempt organizations under Section 501(c)(3) and emphasizes the importance of education and environmental stewardship, ensuring a cleaner and more attractive world for all.

The Pathway to Stop Diabetes Accelerator Award supports innovative early-career researchers tackling diabetes-related challenges. It offers flexible funding up to $325,000 annually for transformative research. Candidates must have independent faculty status and demonstrated productivity in diabetes research. The program aims to inspire groundbreaking discoveries by providing essential resources and mentorship, thereby improving the lives of those affected by diabetes. Nominations focus on translational research that bridges basic science with practical benefits for patients.

The Pathway to Stop Diabetes Initiator Award (INI) aims to support early career researchers in diabetes research by providing funding and mentorship. With a focus on innovative and transformational ideas, this initiative encourages researchers to develop groundbreaking solutions for diabetes prevention and management. The award offers up to $100,000 annually in Phase 1 and $325,000 in Phase 2, fostering a new generation of leaders committed to improving the lives of those affected by diabetes.

The McKnight Clinical Translational Research Scholarship supports young investigators focusing on cognitive aging and age-related memory loss. Funded by the McKnight Brain Research Foundation, this scholarship offers $65,000 annually for two years, plus an education stipend. Eligible applicants should have completed their PhD or residency within the last five years and conduct their research in accredited U.S. institutions. The award emphasizes rigorous training and aims to foster careers in human cognitive aging research.

The Alzheimer’s Foundation of America Bi-Annual Grant aims to support nonprofit organizations in their efforts to enhance the lives of individuals impacted by Alzheimer’s disease and related dementias. Each grant, valued at $6,000, is awarded twice a year, focusing on innovative programs and services. AFA emphasizes partnership and collaboration, enabling grantees to manage their own policies and programs while adhering to specific funding guidelines. This initiative underscores AFA's commitment to compassionate care and ethical standards.

The RFA: Biology to Prevention Award (CRUK) aims to foster innovative translational research that enhances understanding of cancer biology, ultimately leading to effective prevention strategies. Joint applications from UK and US research teams are encouraged, with a focus on equal partnerships and complementary expertise. The funding provides up to £600,000 for UK costs and up to $946,000 for US costs, supporting projects of 1 to 5 years duration that address critical research questions in cancer prevention.

The BJA FY26 Body-Worn Camera Policy and Implementation Program aims to assist law enforcement agencies in acquiring body-worn cameras and establishing comprehensive BWC programs. This initiative addresses the increasing demand for reliable video evidence in criminal cases, enhancing documentation and prosecutorial outcomes. By utilizing BWCs, agencies can deter assaults on officers and protect them against false accusations, ultimately improving community trust and accountability in law enforcement practices.

The American Epilepsy Society offers Research and Training Fellowships for Clinicians, providing up to $75,000 for one year to support clinical fellows or new faculty aiming to advance in epilepsy research. This fellowship encourages proposals across basic, translational, and clinical research. It also includes $1,000 for travel to the AES Annual Meeting, membership benefits, and complimentary registration, fostering collaboration and knowledge sharing in the epilepsy research community.

The Autism Speaks Predoctoral Fellowship aims to support early career autistic scientists in their research endeavors. By providing a two-year fellowship that includes a $40,000 annual award, the program seeks to enhance research training opportunities for promising candidates. Fellows will collaborate with leading mentors in autism research, ensuring that individuals with both academic expertise and lived experience can significantly contribute to advancements in the field. This initiative underscores Autism Speaks' commitment to fostering inclusivity and innovation in autism research.

The Alliance for Innovation on Maternal Health (AIM) program aims to enhance maternal health outcomes by providing technical assistance across all U.S. states and territories. This initiative focuses on implementing best practices to improve safety during childbirth, ultimately saving lives. By supporting jurisdictions and birthing facilities involved in AIM, the program seeks to promote quality improvements in maternal health care, ensuring safer births and better health for mothers and infants.

The Jacques Pepin Foundation (JPF) is dedicated to advancing culinary arts education by supporting community kitchens that provide culinary training to individuals facing employment barriers. Grants of up to $10,000 are available for nonprofits to enhance their culinary programs, including operating costs and facility improvements. Eligibility extends to organizations funded in prior cycles, those that applied but were not funded, and newcomers to JPF funding. This initiative aims to empower underserved communities through culinary skills.

The Community Impact Grants by the Golden Civic Foundation aim to enhance the quality of life in the Golden Community by funding innovative projects that address civic needs. Eligible applicants include 501(c)(3) organizations, local government agencies, and public schools operating within Golden. The grants focus on areas like civic development, arts and culture, social services, education, and environmental sustainability, supporting initiatives that uplift residents and foster community collaboration.

The Tommy Wells Foundation Grant supports youth aged 4-18 in music and hockey programs by providing financial assistance. As a 501(c)(3) nonprofit, the Foundation raises funds to honor Tommy Wells' legacy. Organizations in the greater Nashville, TN area are preferred for funding. The TWF encourages applicants to request funds for those who will benefit most, ensuring accountability by requiring confirmation of fund usage within a year.

The Lymphoma Scientific Research Mentoring Program (LSRMP), offered by the Lymphoma Research Foundation, provides essential mentorship and education for clinical fellows and junior faculty focusing on lymphoma research. With two tracks, one clinical and one laboratory/translational, the program aims to cultivate research skills and foster collaborations. Participants will receive guidance on project development, statistical analysis, and grant submission, ensuring they are well-equipped for future research endeavors in lymphoma and chronic lymphocytic leukemia.