Best Grants for 501(c)(3) in District of Columbia

FY26 McKinney-Vento Homeless Assistance

The Office of the State Superintendent of Education (OSSE) will issue a Request for Applications for the fiscal year 2027 (FY27) McKinney-Vento Homeless Assistance Grant Program (MKV) for eligible Local Educational Agencies (LEAs) in the District of Columbia. Authorized under Title VII-B of the McKinney-Vento Homeless Assistance Act, Section 726, as amended, the purpose of this grant is to facilitate the enrollment, attendance, and success in school of homeless children and youth.

Length of Award:

The grant award period will be from October 1, 2026, or the date of the award if awards are made after this date, through September 30, 2027. LEAs must commit to obligate all grant funds awarded under this competition (RFA# GD0-MKV-FY2027) by September 30, 2027. Awards may be continued for a maximum of one additional year. Continuation awards are based on availability of funds; recipient’s implementation and/or operation of the program as submitted in the application; recipient’s demonstration that substantial progress has been made toward meeting the objectives set forth in the approved application, based on ongoing monitoring and review of the recipient’s reports; compliance with District and federal laws, regulations, and guidance; and appropriate expenditure of funds throughout each grant award period. All awards will be reviewed annually for consideration of continued funding.

Available Funding for Award:

A total of at least Three Hundred Thousand Dollars and Zero Cents ($300,000.00) in grant funds are available for award. District of Columbia LEAs shall use the funds to address the educational and related needs of homeless children and youth in DC. LEAs, with or without this funding, must ensure that children and youth experiencing homelessness have equal access to the same free, appropriate public education, including public preschool education, as provided to other children and youth. OSSE anticipates awarding 3-6 subgrants based on the highest-ranking applications. Grant funds shall only be used to support activities authorized by relevant statutes and regulations and that are included in the applicant’s submission.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

MBSYEP Pathways to STEM Grant

DOES connects District of Columbia (District) residents, job seekers, and employers to opportunities and resources that empower fair, safe, and effective working communities. DOES provides a range of programs and services to jobseekers, including job development, job search assistance, self-directed job search, vocational training, apprenticeship, unemployment insurance, transitional employment, and referrals to supportive services and educational programs.

The Office of Youth Programs (OYP) develops and administers workforce development programs for District youth. OYP provides occupational skills training, work experience, academic enrichment and life skills training to facilitate the development of work habits and skills that are essential for success in the workplace.

DOES, through OYP, is seeking applications for the District’s Marion Barry Summer Youth Employment Program (MBSYEP) Youth Pathways to STEM (Science, Technology, Engineering, Mathematics) Grant. The MBSYEP Youth Pathways to STEM Grant will provide District youth who are interested in becoming STEM professionals with a 6-week learning experience that includes 5-weeks of in-person career exploration and five (5) days must be dedicated to visiting colleges and universities across the country to experience student life in a STEM-related major.

Up to $150,000.00 is available in total for awards through this RFA.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

Equitable Food Access Initiative: Produce Incentives

The total funding amount of $2,100,000 is anticipated for one (1) award for the first budget period. 

The mission of DC Health is to promote and protect the health, safety, and quality of life of residents, visitors, and those doing business in the District of Columbia. The agency is responsible for identifying health risks; educating the public; preventing and controlling diseases, injuries, and exposure to environmental hazards; promoting effective community collaborations; and optimizing equitable access to community resources.

The Community Health Administration (CHA) within DC Health works to prevent the leading causes of death, protect and promote the health of mothers and children, and eliminate racial and ethnic health disparities. CHA’s approach targets multiple factors that influence health through evidence-based programs, policies, and systems change.

The purpose of this funding is to attract qualified applicants to implement evidence-based or evidence-informed strategies to increase food access and improve food environments for District residents with lower incomes through farmers’ market produce incentives.

The Department of Employment Services (DOES) connects District of Columbia (District) residents, job seekers, and employers to opportunities and resources that empower fair, safe, and effective working communities. DOES provides a range of programs and services to jobseekers, including job development, job search assistance, self-directed job search, vocational training, apprenticeship, unemployment insurance, transitional employment, and referrals to supportive services and educational programs.

DOES, Office of Workforce & Federal Programs Out-of-School Youth Program (OSY) provides occupational skills training, career awareness counseling, work readiness modules, basic education, GED preparation, supported internship experiences, vocational skills training, and pre-apprenticeship. Out-of-School programs serve young adults ages 16 - 24 who are no longer attending secondary or post-secondary school. It is a training vehicle that assists youth in achieving short and long term educational and employability goals through relevant occupational skills training and guidance.

OSY Pre-Apprenticeship Grant

Purpose

The goal of OSY Pre-Apprenticeship grant is to equip out-of-school youth ages 16 – 24 in Washington, DC with pathways to high-demand careers through traditional and nontraditional industry-aligned training, stackable credentials, and unsubsidized job placement. This structured program, up to 16-weeks in length, provides participants who are actively seeking unsubsidized employment with the opportunities to build career readiness, strengthen both technical & workplace skills, as well as gain exposure to the workforce. Program providers are responsible for delivering comprehensive career readiness training, recruiting and maintaining partnerships with pre-apprenticeship employer host sites, and facilitating participant placement and matching appropriate work experiences in the following industries. The goal is to prepare participants for entry into a registered Apprenticeship program or direct placement into unsubsidized employment within the pre-apprenticeship scope, while maintaining and creating sustainable pathways to longterm career success.

Department of Behavioral Health

The Department of Behavioral Health provides prevention, intervention and treatment services and supports for children, youth and adults with mental and/or substance use disorders including emergency psychiatric care and community-based outpatient and residential services.

DBH serves eligible adults, children and youth and their families through a network of community based providers and unique government delivered services. It operates Saint Elizabeths Hospital—the District’s inpatient psychiatric facility.

Youth Recovery Residence with Intensive Care Management

Purpose

The purpose of this RFA is to select an applicant through a competitive application review process to establish a ten (10) bed YRR that provides safe, substance-free housing combined with comprehensive care management and RSS for young adults (ages 18–24) with OUD and/or STUD. The program will integrate peer recovery coaching, life skills training, education and employment support, and strong clinical linkages for ongoing treatment, including MOUD. The goal is to provide young adults with the foundation they need for longterm recovery, stability, and community reintegration. The YRR initiative will focus on providing six to twelve months of recovery housing support to young adults (ages 18–24) with OUD and/or STUD. 

The objectives of the initiative are:

• Objective 1: Create housing for young adults (18–24 years) that provides comprehensive, family-centered, recovery-oriented services.
• Objective 2: Support sustained recovery from OUD and/or STUD among residents.
• Objective 3: Promote housing stability and independent living skills.
• Objective 4: Increase educational attainment and/or workforce readiness of residents.
• Objective 5: Strengthen family and community connections for residents.

Office of the Deputy Mayor for Planning and Economic Development 

The Office of the Deputy Mayor for Planning and Economic Development (DMPED) assists the Mayor in the coordination, planning, supervision, and execution of economic development efforts in the District of Columbia with the goal of creating and preserving affordable housing, creating jobs, and increasing tax revenue. DMPED pursues policies and programs that create strong neighborhoods, expand and diversify the local economy, and provide residents with pathways to the middle class.

 Washington, DC Global Soft Landing Grant 

The Office of the Deputy Mayor for Planning and Economic Development (“DMPED”) invites the submission of applications from qualified organizations for a grant under the Washington, DC Global Soft Landing (“GSL”) initiative (the “Program”). The purpose of the GSL Initiative is to support international entrepreneurs, startups, and companies seeking to establish operations in the District of Columbia (“District”).

The GSL initiative connects international entrepreneurs and startups to a network of economic developers, local government, universities, chambers of commerce, and business service providers to support a successful market entry into Washington, DC. Through the Program, DMPED intends to award funds to a Program Operator to manage and coordinate a comprehensive suite of services for international companies navigating the U.S. market entry process (“Project”). Grant funds are intended to support the day-to-day operations of the GSL initiative, as further outlined in the RFA.

The Sara E. and Bruce B. Collette Postdoctoral Fellowship in Systematic Ichthyology, funded by the Smithsonian Institution, supports postdoctoral research in collections-based systematic ichthyology. Established in 2017, this fellowship aims to foster the next generation of researchers through access to the National Museum of Natural History's extensive collections. Awardees receive a stipend of $62,000 annually, as well as allowances for research, travel, and health insurance, making it a prestigious opportunity for scholars in the field.

The Extension Risk Management Education (ERME) Competitive Grants: Exploratory Projects aim to enhance agricultural producers' economic viability through innovative risk management education. Funded by the University of Delaware, these grants offer up to $10,000 for projects that address emerging risk topics or support producer workshops. With an 18-month duration from April 2026 to September 2027, this initiative encourages the development of new educational approaches to better serve the needs of farmers and ranchers.

Our Mission

We are dedicated to empowering organizations that promote the arts and develop programs designed to inspire, educate, and engage. Our vision is a world where the arts are not viewed as a luxury or elective, but as a vital part of every individual’s development and well-being.

Through strong community partnerships, we harness the transformative power of the arts to elevate educational outcomes, foster creativity, and enhance quality of life.

We believe in the synergy that arises when artists, educators, advocates, and creatives from all disciplines—musicians, museum professionals, actors, writers, and teachers—come together and collaborate. It is scientifically proven that the arts play a fundamental role in youth development, nurturing healthy brain function, social growth, and emotional resilience.

Aligned with our mission, we also support initiatives that protect and utilize nature as a source of enrichment and healing. Conservation and beautification efforts are not only essential to environmental health but also to individual and community well-being. Research consistently shows that time spent in nature supports both physical and mental health, especially for children. We are committed to partnering with organizations that recognize the vital connection between a thriving natural environment and a thriving population.

Equally important is our dedication to supporting veterans. We recognize the sacrifices made by servicemen and women and believe they deserve meaningful pathways to recovery, healing, and renewed purpose. That’s why we invest in programs that provide therapeutic support, service animals, respite opportunities, and community-centered initiatives that help veterans and their families thrive. Veterans’ well-being is not only a moral imperative but also a cornerstone of a strong, resilient community.

As a charitable foundation, we remain committed to supporting initiatives that drive progress, improve lives, and create lasting, positive impact across the arts, the environment, education, and veteran support.

The P/Arts Program

The P/Arts Program was created to strengthen connections between the philanthropic, arts, and education communities, fostering meaningful collaborations that enrich learning and inspire growth.

Eligible applicants must be accredited 501(c)(3) organizations that integrate visual and/or performing arts education into their work. Through P/Arts, we seek to support programs that:

• Revitalize learning by enhancing and transforming outdated public school curricula.
• Motivate and inspire students of all ages, encouraging curiosity, creativity, and lifelong learning.
• Empower educators by deepening professional development opportunities for teachers, professors, and childcare providers.
• Bridge the gap between school and home, creating continuity in learning and support for children and families.
• Apply evidence-based, arts-based instruction proven to strengthen both academic and personal outcomes.
• Address inequities in education by helping to close the achievement gap and expand access to high-quality learning opportunities.

At its heart, the P/Arts Program reflects our belief that the arts are a powerful driver of educational transformation, unlocking potential not just in the classroom but in entire communities.

The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.

Foundation for Children with Intellectual and Developmental Disabilities

The FCIDD was founded for the purpose of providing support to organizations that serve individuals with intellectual and developmental disabilities.

Mission Statement: The Foundation supports organizations which enhance the lives of persons with intellectual and developmental disabilities by promoting research, projects, education and advocacy. 

Nonprofit Project Grants

The Foundation for Children with Intellectual and Developmental Disabilities (FCIDD) funds 501(c)(3) organizations working with individuals with intellectual and developmental disabilities of all ages, primarily in the states of Maine, New Hampshire, Vermont, Massachusetts, Rhode Island, Connecticut, New York, New Jersey, Pennsylvania, Ohio, West Virginia, Delaware, Maryland, the District of Columbia, and Virginia. 

Funding Priorities

• Grants will be awarded for the purpose of primarily benefiting, including, or increasing accessibility for individuals with intellectual or development disabilities.
• Grants may be awarded for scholarships or training personnel in the care and education of individuals with developmental and/or intellectual disabilities. 
• Grants shall mainly be distributed to a Charity whose primary purpose or whose project is to support individuals with intellectual or developmental disabilities. A Charity which has a project to benefit individuals with developmental or intellectual disabilities based on financial need shall be awarded the grant money based upon its own objective criteria and without any special preference to members of Civitan or members of their family.

Grant Categories

A grant application typically fits into one of the following categories: Accessibility & Engagement; Educational Spaces; Program Area Improvements; Outreach and Education 

Accessibility & Engagement

For museums, parks, other public spaces without a specific I/DD focus wanting to make property or equipment improvements and additions to better include visitors with I/DD.

The WAVForce Incentives Project aims to enhance the availability of wheelchair accessible vehicles (WAVs) in Washington, D.C., by incentivizing drivers and fostering partnerships within the for-hire industry. This initiative, backed by the District of Columbia Department of For-Hire Vehicles, seeks to ensure 24/7 WAV service availability while promoting self-sustainability through strategic collaborations. By dedicating significant funding towards driver incentives, the project intends to improve operational capacity and service quality for the community.

The Jacquilyn Billey Memorial Scholarship, offered by the National Federation of the Blind, provides thirty merit-based scholarships of $10,000 each to legally blind students pursuing post-secondary education in the U.S. The scholarship emphasizes academic excellence, community service, and leadership. Finalists are selected in spring and must attend the NFB National Convention in July for the award announcement. This initiative empowers blind individuals to pursue their educational and career aspirations, reflecting a commitment to inclusivity and opportunity.

The Ernest Morgan Memorial Scholarship, managed by CommunityGiving, supports central Minnesota student athletes and leaders to pursue higher education outside their home states. This scholarship aims to expand students' horizons and experiences, with a total award of $5,000 available. Open to high school seniors from specific schools, applicants are encouraged to apply online and demonstrate their leadership or athletic skills. This initiative enhances educational opportunities and fosters personal growth among local youth.

The Great American Cleanup Grants, offered by Keep America Beautiful, aim to enhance community beautification and environmental efforts across the U.S. This initiative encourages KAB affiliates to remove litter, plant greenery, and restore public spaces, contributing to the larger goal of cleaning up 25 billion pieces of litter by 2026. With cash grants available, this program fosters collaboration among communities, promoting sustainable practices and a cleaner, greener future for all.

The Kenneth Jernigan Scholarship, offered by the National Federation of the Blind, honors the legacy of Jacquilyn Billey, a dedicated advocate for the blind. With thirty merit-based scholarships of $10,000 each available, applicants must be legally blind, reside in the U.S., and plan to pursue full-time post-secondary education. Awards are based on academic excellence, community service, and leadership, with finalists attending the NFB National Convention in July for selection.

The Emeril Lagasse Foundation offers Community Grants aimed at supporting 501c3 non-profit organizations that focus on culinary, nutrition, and arts education, with an emphasis on life skills development. Grants are available to organizations in communities where the foundation operates, including Greater New Orleans, Austin, and Southern California. Eligible applicants must demonstrate a commitment to inclusivity and align with the foundation's vision of empowering youth to reach their full potential.

The Rosendin Foundation Annual Grant provides financial support to community-focused 501(c)(3) non-profit organizations across various states, aiding initiatives in emotional, occupational, and nutritional health. Grants can reach up to $50,000 and are geared towards organizations that positively impact their communities. However, the foundation does not fund discriminatory practices, political efforts, or religiously affiliated projects, ensuring that support is directed towards inclusive and impactful community services.

The Cultural Humility Training Grant, offered by the District of Columbia Mayor’s Office on Volunteerism & Partnerships, aims to empower community-based organizations (CBOs) to enhance cultural competency and provide affirming spaces for youth, particularly those experiencing homelessness. This two-year initiative supports CBOs in delivering tailored training, improving service delivery, and fostering inclusive environments. The grant period extends from October 1, 2025, to September 30, 2027, focusing on evidence-based practices to better serve vulnerable populations.

The Express Health Information Outreach Awards aim to enhance public health by increasing access to biomedical information for U.S. health professionals and the general public. These awards support projects that improve health information literacy among consumers and caregivers, ensuring they can effectively find and utilize health information. Focused on partnerships and outreach to underrepresented communities, the initiative seeks to promote healthy behaviors, prevent illness, and improve health outcomes through informed decision-making.

Department of Behavioral Health

The Department of Behavioral Health provides prevention, intervention and treatment services and supports for children, youth and adults with mental and/or substance use disorders including emergency psychiatric care and community-based outpatient and residential services.

DBH serves eligible adults, children and youth and their families through a network of community based providers and unique government delivered services. It operates Saint Elizabeths Hospital—the District’s inpatient psychiatric facility.

Hospital -Based Peers Support Services

The Government of the District of Columbia, Department of Behavioral Health, Adult Services Administration is soliciting applications from qualified organizations to implement the Hospital-Based Peer Support Services program under the District of Columbia Opioid Response (DCOR) grant. The DCOR grant, guided by LIVE.LONG.DC.(LLDC), is focused on increasing access to medications for opioid use disorder (MOUD) treatment, reducing unmet treatment needs, and reducing opioid overdose-related deaths in the District of Columbia through the provision of prevention, harm reduction, treatment, and recovery support services (RSS) to individuals with stimulant use disorder (STUD) and opioid use disorder (OUD).

Target Population

The target population is individuals who have OUD and/or STUD that receive care in a participating hospital within the District of Columbia. Individuals may be in the hospital ED or an inpatient unit for OUD/STUD-related reasons (e.g., overdose or injection-related infection) or for any other reason. 

The Great Apes and Gibbons Program Grant, administered by the Arcus Foundation, supports conservation efforts for great apes and gibbons across 24 priority landscapes in Africa and Asia. The program emphasizes sustainable coexistence between humans and wildlife, having awarded over 2,000 grants to more than 500 organizations globally. Funding is not available for individuals or specific lobbying activities, ensuring resources are directed towards impactful conservation initiatives.

Department of Energy and Environment

The Department of Energy and Environment (DOEE) is the leading authority on energy and environmental issues affecting the District of Columbia. Using a combination of regulations, outreach, education, and incentives, our agency administers programs and services to fulfill our mission. We work collaboratively with other government agencies, residents, businesses, and institutions to promote environmentally responsible behavior that will lead to a more sustainable urban environment.

Efficient Affordable Resilient Neighborhoods (EARN) Initiative

DOEE seeks eligible entities to develop a deployment plan for neighborhood-scale electrification and clean energy implementation that improves energy efficiency, affordability and resilience outcomes in one or two District neighborhoods. This is a planning grant. It does not fund implementation.

The Training for Emerging Cyber Heroes (TECH) Force Grant, provided by the District of Columbia Office of the Deputy Mayor for Public Safety and Justice, aims to support innovative cyber safety initiatives. This grant encourages the development of programs that empower youth with cybersecurity skills, promoting public safety and digital resilience. Organizations focused on cybersecurity education and youth engagement are encouraged to apply. The deadline for applications is June 29, 2026.

About Us

The Office of the Attorney General (OAG) is the chief legal office of the District of Columbia. The Office enforces the laws of the District, defends and provides legal advice to District government agencies and protects the interests of DC residents. OAG’s goal is to be the nation’s most effective and respected public law office.

Leaders of Tomorrow – Youth Violence Prevention Grant

The Office of the Attorney General (“OAG”) is seeking proposals from non-profit Community-Based Organizations (CBOs), interested in operating the Leaders of Tomorrow: Youth Violence Prevention Grant Program to identify and mitigate risk factors associated with youth violence and contribute to the long-term wellbeing and success of young individuals. OAG recognizes the importance of providing financial support to local non-profits dedicated to identifying and mitigating risk factors associated with youth violence. These organizations play a crucial role in developing strategies that align with promising and evidence-based approaches, ultimately contributing to the long-term wellbeing and success of young individuals. OAG will make up to $100,000 in funding per grant per organization available for Fiscal Year 2025. Total grant funding will not exceed $500,000.