Best Grants for Small Nonprofits in District of Columbia

The Goodwine Scholarship, offered by the Erie Community Foundation, supports graduating seniors from public or private high schools in Erie County pursuing a two-year associate degree or certificate. In 2023, the foundation awarded over $800,000 in scholarships to more than 500 students, ensuring they have the opportunity to further their education and skills. Applicants must maintain a minimum GPA of 2.0 to qualify for this valuable support.

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The Westminster Presbyterian Church Scholarship aims to address contemporary community needs by providing financial support for education and job training. This initiative, led by the Community Foundation of Elmira-Corning and the Finger Lakes, emphasizes a holistic approach to community welfare, including arts, infrastructure, and wellness. It is designed for individuals who are currently employed full-time and seeking further education or job training opportunities.

The Multiple Sclerosis Clinical Care Physician Fellowship: Pediatric Care, offered by the National Multiple Sclerosis Society, aims to enhance the training of physicians in providing specialized care for pediatric patients with MS. This one-year post-residency program emphasizes direct patient care and multidisciplinary collaboration. Participants will learn under the supervision of MS specialists, gaining essential skills to improve clinical practices and contribute to the MS community, ultimately leading to better outcomes for those affected by this condition.

The Sidney R. Baer, Jr. Foundation offers Clinical Research Grants to support advancements in the treatment and understanding of schizophrenia and bipolar disorder. Focused on organizations with IRS tax-exempt status, these grants aim to enhance mental health services and research. By funding initiatives in cognitive and behavioral sciences, the foundation seeks to improve the lives of those affected by serious mental illness, ensuring they receive the support and resources necessary for a better quality of life.

The Katie Moore Memorial Nursing Scholarship, administered by the Community Foundation of North Central Washington, supports students pursuing a Bachelor of Science degree in nursing. Preference is given to those specializing in pediatric nursing and with relevant experience. Eligible candidates must have completed two years of college with a minimum GPA of 3.5 or be enrolled in an RN to BSN program. This scholarship honors Katie Moore's legacy and aims to foster compassionate care for children.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

The BioMarin Grant aims to support events, activities, and projects that enhance public health and benefit patients with rare diseases. This corporate funder focuses on scientific innovation and provides resources for organizations such as hospitals, universities, and patient advocacy groups. With an emphasis on education and community support, BioMarin encourages applications for funding throughout the year, ensuring timely assistance for eligible projects.

The Kathryn Lodge Mhatre Creative Writing Scholarship honors the memory of Kathryn Lodge Mhatre, a passionate writer and compassionate individual who tragically lost her battle with mental illness. Established by her parents, this scholarship supports students from Chelan or Douglas County pursuing creative writing. Eligible applicants must have a minimum 3.0 GPA and provide a writing sample, reflecting Kathryn's dedication to learning and her love for storytelling.

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

The Youth Regional Treatment Center Aftercare Program aims to support American Indian and Alaska Native youth in maintaining safety, sobriety, and success post-discharge from Youth Regional Treatment Centers. This initiative enhances culturally relevant, community-based aftercare by fostering care coordination, building partnerships, and addressing barriers to improve youth outcomes.

The Kidney Health Equity Community Engagement Award by the National Kidney Foundation aims to enhance health equity in kidney care. This award encourages innovative proposals that address disparities in access to kidney care, education, and treatment. With a funding of $75,000 for one year, it supports healthcare professionals and researchers in implementing community-based solutions to improve outcomes for individuals affected by kidney disease. The initiative seeks to dismantle barriers and foster equitable health practices.

The Urban Indian Health 4-in-1 Program is designed to enhance the health and well-being of urban Native Americans through targeted initiatives in immunization, health promotion, disease prevention, mental health support, and addressing alcohol and substance abuse issues. Funded by the US Dept. of Health & Human Services, this program aims to improve access to essential health services and foster healthier communities among urban Indian populations.

The Chronic Pain Medicine Research Grant, offered by the American Society of Regional Anesthesia (ASRA) and Pain Medicine, aims to enhance research in pain medicine, guiding clinical practice and improving patient care. With a funding limit of $200,000, the grant prioritizes studies in areas such as Regional Anesthesia, Outcomes Research, and Patient Safety, encouraging innovative proposals from North American physician members of ASRA.

The Undergraduate Development Program Student Travel Award offers undergraduate science majors a unique opportunity to attend the Society of Toxicology Annual Meeting from March 21–23, 2026. The program aims to inspire students pursuing research careers in toxicology and related biomedical sciences. Participants will engage with professionals, attend sessions, and explore various educational and career paths. SOT emphasizes inclusiveness, encouraging diverse perspectives to enhance innovation in the field.

The John E. Mayfield ABLE Scholarship Fund supports graduating seniors who are participants in the ABLE program, enabling children with disabilities to excel in post-secondary education. Established by John Mayfield, this scholarship encourages individuals to pursue their educational dreams, fostering independence and productivity within the community. The Community Foundation of Middle Tennessee, with over 30 years of philanthropic experience, administers the fund to ensure resources are directed where they can make the greatest impact.

The Tribal Epidemiology Centers initiative aims to support currently unserved areas through a new cohort of TEC sites. Funded by the US Dept. of Health & Human Services: Indian Health Service, this program seeks to enhance public health capacity within tribal communities, ensuring access to essential health services and resources. The initiative underscores a commitment to addressing health disparities and promoting wellness among Native populations.

The DoW Kidney Cancer Early-Career Scholar Award is a unique initiative by the Academy of Kidney Cancer Investigators, established in FY19. It aims to foster innovative kidney cancer research through a mentoring program that pairs early-career scholars with experienced mentors. This program not only enhances research capabilities but also builds a robust network of kidney cancer researchers. By supporting promising scholars, the initiative aspires to advance the field and improve treatment outcomes for kidney cancer patients.

The Bill Monroe Memorial Scholarship, managed by the Brown County Community Foundation, offers financial support to graduates of Brown County High School pursuing a full-time baccalaureate degree in music or a related field. This scholarship is open to current and previous graduates, including those participating in Bluegrass music mentoring programs. The foundation has a strong focus on education and has facilitated numerous scholarships, enhancing opportunities for local students since its establishment.

The James E. Bugley Scholarship, managed by the Berkshire Taconic Community Foundation, honors the memory of Jamie Bugley, a talented musician and dedicated community member. Established to support high school seniors from Berkshire County, MA, this scholarship encourages students pursuing careers in music or vocational arts. With a mission to promote economic mobility and quality of life, it reflects the foundation's commitment to philanthropy and leadership in the community.

The FY26 Kidney Cancer Research Program's Idea Development Award supports innovative research that enhances understanding of kidney cancer, aimed at improving patient outcomes. Proposals should feature a strong hypothesis and a detailed research plan, with team members experienced in kidney cancer research. A unique aspect is the Partnering Principal Investigator option, fostering collaboration between two investigators, ensuring comprehensive project development while allowing for distinct submissions. This award emphasizes impactful partnerships to drive advancements in the field.

The ASES Research Grant, provided by the ASES Foundation, offers up to $20,000 for innovative shoulder and elbow research projects. It invites applications from principal investigators who are orthopaedic surgeons working in North America. The funding supports projects lasting between 12 to 24 months and aims to foster advancements in patient care through research. Applications are limited to one per principal investigator per year, promoting focused and impactful research initiatives.

The Growing Convergence Research (GCR) initiative by the National Science Foundation (NSF) promotes innovative solutions to complex societal and scientific challenges through multidisciplinary collaboration. By integrating diverse expertise, GCR aims to address specific problems and foster new research paradigms. Proposals must outline a five-year plan, divided into two phases, with budgets not exceeding $1.2 million for Phase I and $2.4 million for Phase II. Successful projects are expected to lead to transformative advances in science and technology.

The Fund for Wild Nature Grant empowers small non-profit organizations in Canada and the U.S. that prioritize the preservation of native species and ecosystems. With a biocentric approach, this grant supports innovative initiatives combating environmental degradation. Organizations must be tax-exempt and can only submit one proposal annually. Grants do not exceed $3,000, ensuring funding is directed to impactful projects addressing ecological issues often overlooked. Join the Fund in investing in the future of wild nature!

Howard Hughes Medical Institute

More than 70 years ago, the Howard Hughes Medical Institute (HHMI) was founded with a mission to advance basic biomedical research and science education. Today, we invest in exceptional scientists at all career stages, catalyzing breakthroughs, new technologies, and the next generation of transformative clinical therapies. Our pathbreaking science takes place at more than 60 host institutions across the US, and at our Janelia Research Campus.

Cech Fellows Program

The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders. 

The Summer Undergraduate Research Program (the Cech Fellows Program) gives undergraduate students in the life sciences the opportunity to conduct hands-on research alongside leading scientists at HHMI laboratories across the US, from universities and research institutions to HHMI’s research campus outside of Washington, DC. Students are matched with HHMI scientists conducting fundamental research that advances our understanding of biology and health.

This immersive program gives students the chance to contribute to real scientific discovery, gain professional mentorship, and explore potential careers in biological and biomedical research.

Gain Hands-On Experience in Research & Lab Work

Through the summer, students will:

• Work full time conducting research and contributing to ongoing projects in an HHMI laboratory
• Learn and practice new techniques and approaches in disciplines such as cell biology, genetics, neuroscience, and more
• Work closely with and be mentored by exceptional scientists, from lab heads to PhD students
• Build critical thinking and communication skills necessary for future research careers

What the Program Offers

Beyond meaningful lab work, the program provides:

• A stipend to support summer travel, housing, and living expenses 
• An opportunity for participants to present their research and connect with a national cohort of peers at an end-of-summer research symposium at HHMl’s research campus outside of Washington, DC 
• An engaging virtual seminar series with HHMI scientists as well as professional development sessions focused on relevant skills building

The Stout Foundation Grant supports organizations aligned with the values of its founder, Mr. Stout. Grants are awarded exclusively to entities with 501(c)(3) tax-exempt status and focus on charitable, educational, and scientific purposes. Preference is given to organizations with low overhead costs and those located in areas frequented by Foundation members. The Foundation aims to promote effective use of funds while remaining flexible in its grant-making approach.

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Senior Master Sergeant Texie C. Taylor, USAF Memorial Scholarship

Applicant must be a junior or senior undergraduate or graduate student majoring in physics, chemistry, biology, medicine, nursing (RN), engineering (aerospace, civil, chemical, electrical, mechanical) or mathematics with a minimum 3.0 GPA. This is a one-year scholarship reserved for Cherokee Nation citizens residing within the Cherokee Nation jurisdictional area.