Best Large Grants for Nonprofit Organizations in District of Columbia

The Estelle Massey Osborne Scholarship supports exceptional African American nurses pursuing master's degrees. Applicants must have at least two semesters remaining in their program, maintain a minimum GPA of 3.6, and hold a current RN license. This scholarship, provided by Nurses Educational Funds Inc., honors Estelle Massey Osborne, the first African American nurse to earn a master's degree in the U.S. It aims to promote nursing leadership through financial assistance for advanced education.

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Scholarships

At South Dakota Community Foundation (SDCF), we proudly manage more than 350 scholarship funds in partnership with generous donors who are committed to supporting students. These scholarships offer countless opportunities to help ease the financial burden of continuing their education.

Spearfish Volunteer Firefighters' Association Scholarship

To provide financial support to individuals pursuing an education and training in the public safety industry.

The Spearfish Fire Department, established in the late 1880s as a volunteer organization, serves the northern Black Hills in western South Dakota. Its mission is to protect lives and property within the fire protection district and mutual aid area. Additionally, the department advocates for fire safety and provides fire safety education in local schools and the wider community.

The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.

The Alzheimer’s Association's Center for Dementia Respite Innovation Grant (CDRI) supports innovative respite care projects, aiming to improve person-centered dementia care across the U.S. With up to $20 million available over five years, the grant encourages local respite care providers to enhance their services through collaboration and innovative solutions. Recipients will receive training and assistance to ensure their programs are effective and sustainable, addressing the growing need for quality dementia care.

The NMDP Barbara Buchbinder Nurse Research Program Grant supports pediatric BMT nurses conducting research to enhance transplant experiences and outcomes for children. With only 4% of federal funding allocated to childhood cancer, this program, honoring a dedicated nurse, aims to attract new talent to the field. Each selected Buchbinder Scholar receives a $25,000 award to pursue relevant investigations, emphasizing the importance of supportive care in pediatric allogeneic hematopoietic cell transplants.

Carl Hill Memorial Scholarship

Awards:

• One time award of $500.

The Agriculture Risk Management Education Partnerships Competitive Grants Program (ARME) aims to educate agricultural producers on various risk management activities, including crop insurance, debt reduction, and market assessment. Emphasizing farm viability, the program seeks to provide technical assistance and outreach to farmers and ranchers to improve their risk management strategies, as outlined in the Agriculture Risk Protection Act of 2000. This initiative is funded by the USDA's National Institute of Food and Agriculture (NIFA).

The Mentored Quantitative Research Development Award (K25) aims to engage skilled professionals in NIH-relevant research, enhancing their expertise in addressing health-related issues. This award supports individuals with backgrounds in quantitative sciences and engineering, providing them with dedicated time for supervised research and study. Key application deadlines span from June 2024 to February 2027, emphasizing the program's commitment to fostering innovative research in health and disease.

The AIDS Drug Assistance Program (ADAP) Emergency Relief Funds aim to provide essential funding to states and territories. This initiative focuses on preventing, reducing, or eliminating waiting lists for ADAP services, ensuring timely access to necessary medications and support for individuals living with HIV/AIDS. This program addresses critical funding shortfalls, enhancing the healthcare infrastructure and improving health outcomes in affected communities.

The National Institutes of Health is launching a funding opportunity to explore the mechanisms of skin injuries caused by toxic chemicals. This initiative aims to understand the common pathways of injury from various harmful substances, facilitating the discovery of therapeutic targets. Researchers are encouraged to collaborate and apply their expertise in cutaneous wound healing. The goal is to develop broad-spectrum medical countermeasures for mass casualty events involving toxic exposures, enhancing public health safety.

• Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
• Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
• Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
• Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.

The NIHCM Foundation's Local Media Award honors outstanding local journalism that enhances understanding of health care issues in the U.S. It aims to recognize reports that improve health care affordability, accessibility, and quality. A $15,000 prize is awarded to the winner. Eligible entries must be published in 2025 and focus on local markets, offering insights relevant to health plans and policymakers. This award encourages innovative reporting that addresses the complexities of the health care system.

Request for Proposals

Community Care Corps encourages organizations across the country to apply for 18-month grants ($30,000–$200,000) to develop and scale innovative volunteer programs that provide nonmedical assistance to older adults, adults age 18 and older with disabilities and family caregivers.

Projects funded through this initiative will increase the number of community-based volunteer programs available to provide nonmedical assistance while decreasing the number of older adults, adults with disabilities, and family caregivers who need assistance in maintaining independence in the community but are unable to obtain help. In doing so, the initiative will strengthen community-based supports that help people maintain independence, reduce unmet needs, and improve overall well-being.

The Stem Cell Grants: Travel Award supports students, postdocs, and faculty attending scientific conferences and workshops related to stem cell research. Up to $1,200 is available for each application, with a maximum of two applications per PI lab each calendar year. Priority is given to those presenting at stem cell meetings and workshops. All applications must be submitted at least one week before travel to ensure funding consideration.

The Florence Merriam Bailey Award, presented by the American Ornithological Society, honors outstanding articles published by early career members in AOS journals within the last two years. Awarded annually, it includes a $1,500 cash prize to the lead author. Papers recognized alternate between the journals 'Ornithology' and 'Ornithological Applications'. Nominees must adhere to high ethical standards as outlined in the AOS Code of Conduct.

The Alliance for Innovation on Maternal Health (AIM) Capacity Program aims to enhance the capacity of state, territorial, and Tribal entities in the U.S. to implement and sustain AIM Patient Safety Bundles. By promoting evidence-based maternal safety practices, the program strives to improve the quality of maternity care, enhance maternal health outcomes, and significantly reduce preventable maternal mortality and severe morbidity.

The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.

The Miller Indigenous Economic Development Fellowship, established by the Native Forward Scholars Fund, provides financial assistance to American Indian and Alaska Native doctoral candidates engaged in economic research impacting Native communities. This fellowship supports costs associated with data collection, analysis, and travel. It aims to enhance the representation of Native scholars in economics, addressing the current underrepresentation in the field. Eligible candidates are encouraged to apply to further their research and contribute to their communities.

The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.

The FY26 Pancreatic Cancer Research Program (PCARP) Idea Development Award promotes innovative, high-risk research aimed at significant advancements for pancreatic cancer outcomes. This award supports projects with preliminary data, focusing on impactful discoveries. It features a Partnering Principal Investigator option, enhancing funding for collaborations between experienced mentors and early-career researchers. All applications must align with the FY26 PCARP Focus Areas, ensuring relevance and potential for transformative results in pancreatic cancer research.

The 1954 Project - Luminary Award seeks visionary nonprofit leaders dedicated to advancing educational equity for Black students. Awardees receive $1 million in funding, leadership development, and networking opportunities. The selection prioritizes leaders demonstrating strategic vision, community commitment, adaptability, and collaborative spirit. Applicants must align with one of three impact areas: Innovation in Teaching and Learning, Diversity in Education, or Pathways to Economic Mobility, ensuring their initiatives foster systemic change and uplift marginalized communities.

The FY26 Pancreatic Cancer Research Program (PCARP) Translational Research Partnership Award encourages collaboration among clinicians and scientists to expedite the clinical application of innovative pancreatic cancer research. A minimum of two Principal Investigators is required, with one designated as the Initiating PI. This award supports preliminary data collection and various research methodologies, excluding large-scale clinical trials, to enhance pancreatic cancer understanding and treatment.

The FY26 DoW Pancreatic Cancer Research Program Focused Pilot Award aims to drive innovative and impactful research in pancreatic cancer, enhancing patient quality of life. This award encourages the development of preliminary data to support future clinical or real-world applications. While allowing for clinical research studies, it does not permit clinical trials or preclinical animal studies, ensuring a strong patient-centered approach in its research focus.

The FY2026 Cooperative Agreement for the 988 Suicide & Crisis Lifeline Administrator aims to enhance and manage the 988 Lifeline, connecting individuals in crisis through various communication methods to a network of certified crisis centers. This initiative seeks to link people with vital emergency, behavioral health, and social services, providing essential support to those in need. The program is funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), emphasizing mental health resources and accessibility.

The Implementing Zero Suicide in Health Systems program aims to enhance suicide prevention efforts for adults within health systems. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this initiative employs a comprehensive approach that incorporates all seven elements of the Zero Suicide framework: Lead, Train, Identify, Engage, Treat, Transition, and Improve. This program seeks to create safer health environments and reduce suicide rates effectively.

The SAF National Awards Program recognizes excellence in forestry through various awards, including the Award in Forest Science. This award acknowledges significant research contributions in quantitative, economic, managerial, and social sciences, promoting advancements in forestry. Recipients receive a $1,000 honorarium, a complimentary SAF convention registration, and travel expense support. Established in 1996, this award highlights the importance of innovative research that impacts both national and international forestry practices.

The SAF National Awards Program recognizes excellence in forestry through various awards, including the Barrington Moore Memorial Award in Biological Science. This award honors individuals for significant contributions to biological research that advances forestry practices. It includes a $1,000 honorarium, convention registration, and travel support. The award celebrates leaders in forest ecology, soil science, and other related fields, promoting innovation and collaboration in forestry research.