Best Large Grants for Nonprofit Organizations in District of Columbia

The Substance Abuse Prevention, Treatment, and Aftercare program aims to combat substance abuse in American Indian and Alaska Native populations. It focuses on enhancing care coordination, expanding culturally competent behavioral health services, and implementing early intervention strategies for at-risk youth. By supporting Tribal and community-led initiatives, the program fosters collaboration among families, youth, and community partners to create effective prevention, treatment, and recovery solutions.

The Municipal Workforce Learning Lab, initiated by the National League of Cities in partnership with the American Institutes for Research, aims to tackle workforce challenges faced by city governments. The program seeks three cities to engage in an 8-month action planning process focused on recruiting, training, and retaining skilled workers. Participants will receive free coaching and technical assistance, helping them enhance their workforce policies and potentially serve as national models for effective local government employment strategies.

The Children and Youth with Special Health Care Needs Research Network aims to enhance the lives of children and youth with special health care needs (CYSHCN) and their families. By establishing a robust research infrastructure, the program will generate evidence-based solutions to foster well-being and community engagement. It focuses on identifying effective interventions and measures that can be integrated into essential services and supports, ultimately helping CYSHCN thrive throughout their lives.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.

The Culpeper Rotary Foundation Scholarship supports residents of Culpeper County pursuing a four-year degree. With a $1,000 award renewable for four years, applicants must demonstrate financial need and maintain a GPA of 2.5 or higher. The Northern Piedmont Community Foundation manages the scholarship application process, emphasizing community involvement. This initiative reflects NPCF's commitment to enhancing educational opportunities in the region, ensuring that local students have the support they need to succeed in their academic pursuits.

The Edith M. Pritchard Scholarship, offered by Nurses Educational Funds Inc., supports nurses pursuing master's or doctoral degrees in nursing education and public health. Applicants must hold a current RN license, maintain a GPA of 3.6, and have at least two semesters of study remaining post-award notification. This scholarship promotes nursing leadership and is funded through donations, reflecting over a century of commitment to nursing education.

The C.V. Glassco Memorial Scholarship Fund honors Mr. Clarence Verbal Glassco, a dedicated community volunteer and veteran. This scholarship supports full-time students pursuing higher education or approved workforce training in Alabama. Funded by the Community Foundation of Northeast Alabama, it covers tuition, housing, and books based on available assets. Applicants are encouraged to seek additional financial resources. This initiative preserves Mr. Glassco's legacy of service and commitment to education.

About Us

We are YOUR Community Foundation! Our mission is to bring people and resources together to strengthen the quality of life, both now and in the future, for the residents of Randolph County.

The Community Foundation of Randolph County, Inc. is here to make our community the very best place to live, work, and raise a family. As a non-political private organization, we are uniquely able to provide grant money for innovative projects that have a major impact on our community.

Donald Forrest Hahn & Wilma Fraley Hahn Memorial Scholarship Fund

Donald Forrest Hahn and Wilma (Fraley) Hahn were high school sweethearts in Hollandsburg, Ohio where they graduated in 1941. Don enrolled at Earlham College, but was drafted into the Army to serve in World War II. He was part of the 3rd Army under the command of General Patton and his unit fought at Normandy Beach on D-Day, in the Battle of the Bulge, and in the battle for the Remagen Bridge. Don received a Silver Star, two Bronze Stars, one with clusters and a purple heart for shrapnel wounds. Don was a member of the Honor Guard for General Patton’s funeral. Wilma obtained her nursing degree from Reid Memorial Hospital. When Don returned from the war in 1946, they married and moved to 298 No. Jackson Street in Winchester where they lived as man and wife for 70 years in that same house. Don passed away on December 24, 2016 and just 30 hours later Wilma died on December 25. Wilma worked as an emergency room nurse from 1946-1949 and then was employed by the Randolph County Hospital from 1950-1968. From 1968 until her retirement in 1986 Wilma was Randolph Central School corporation’s nurse. Don farmed, was a rural route mail carrier, a member of the Lion’s Club and served on the school board for the Randolph Central School Corporation. He was on the board when the new high school was built. Don and Wilma were members of the First United Methodist Church of Winchester for 70 years. Both Don and Wilma were awarded Sagamores of the Wabash. They had three children, Greg, Randy and LeighAnne. Both Don and Wilma valued public school education and held higher education as a priority.

Awarded to a Randolph County, Indiana High School graduate with a financial need. Preference to be given to a student(s) pursuing a degree in Agriculture or Nursing.

The BIE Professional Examination Funding, provided by Native Forward Scholars Fund in partnership with BIE, offers financial assistance to support Native students in taking professional examinations, including Bar Examination funding. This award covers registration fees, preparatory course costs, and other exam-related expenses. Applicants must have graduated within one year and can only receive assistance for one exam. This initiative aims to empower Native scholars and enhance their professional visibility and opportunities.

The Native Forward Community Impact Research Funding supports doctoral candidates conducting research that addresses issues affecting Indian Country. This initiative provides essential financial assistance for data collection, analysis, and research travel, ensuring that Native perspectives are included in academic discourse. By fostering the next generation of Native leaders, this funding aims to empower scholars and enhance community impact through education and advocacy, ultimately preserving and enriching Native cultures.

The Jonathan Sherman Spradling Memorial Scholarship Fund, established in 2023, honors the legacy of Jonathan Sherman Spradling, a dedicated New Mexico resident committed to education and community service. This scholarship provides financial assistance to high school seniors who demonstrate a strong commitment to volunteerism. With a focus on applicants from Valencia County, NM, the fund aims to support students pursuing higher education at accredited institutions while encouraging continued involvement in community service.

The Rotary Works Foundation Grant supports charitable projects primarily focused on children, youth, and families, emphasizing active Rotarian involvement. Grants range from $500 to $5,000, awarded prior to events. Eligible applicants include 501(c)(3) or 501(c)(1) organizations. Preference is given to projects engaging Rotarians. The application deadline is the 2nd Wednesday of each month, and all grantees must report outcomes post-project.

The Native Forward CPA Examination Funding provides crucial financial assistance to American Indians and Alaska Natives for covering the costs associated with the CPA examination. This initiative empowers students and professionals to pursue CPA licensure by assisting with application, registration, and exam fees. Eligible applicants can receive support for one section of the exam at a time, ensuring access to essential resources for advancing their careers and contributing positively to their communities.

The Zonta Club of Greater Sandusky High School STEM Scholarship Fund provides financial support to female high school seniors from Erie, Huron, or Ottawa County, Ohio, who plan to pursue a degree in STEM or medical fields at accredited institutions. Established by the Zonta Club, this scholarship aims to empower young women to contribute positively to their communities by facilitating access to higher education opportunities. Since its inception, it has fostered academic growth and leadership among recipients.

The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

The Native Forward Direct Scholarship supports American Indian and Alaska Native students by providing mid-year funding opportunities to alleviate educational costs. With over 50 years of experience, Native Forward has empowered more than 22,000 students from diverse backgrounds. This scholarship recognizes the limited access these students face in higher education and aims to enhance their academic journeys while fostering community engagement and mentorship through a strong alumni network.

The Teresa and David R. Schmidt, M.D. Scholarship Fund, managed by the San Antonio Area Foundation, supports high school seniors pursuing careers in the medical field. Eligible applicants must demonstrate financial need and maintain full-time enrollment at accredited institutions. This renewable scholarship assists with tuition, fees, and books for students from specific Texas counties, fostering community growth and educational opportunities in healthcare since 1964.

About

Mission, Vision & Values

To enhance our community through philanthropy.

We aspire to co-create diverse, meaningful and innovative charitable giving that yields an exponential positive impact within local communities and beyond.

David Bruce Belcher Fund

About the fund

The David Bruce Belcher Scholarship Fund was established for the training of professionals in nursing, special education, and therapy (physical, speech and occupational) as a legacy of David Bruce Belcher and the caregivers who comforted him. This fund reflects David’s rare spirit and bright love in its support of those who seek to advance their nurturing skills in nursing, therapy, and special education.

Cures Within Reach

Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.

Clinical Repurposing Research to Impact US Veterans/Military

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Eligible trials may be conducted at accredited US-based academic, nonprofit and governmental research institutions and/or health systems involved with medical research, including Veterans Administration (VA) health systems and hospitals. 

Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices, nutraceuticals or diagnostics, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in clinical practice as standard of care. Repurposed therapies also may be added to current standard of care to improve patient outcomes and/or quality of life.

Hutsell, Alan Scholarship Fund

For a high school senior from Central Noble, East Noble, Wawasee, West Noble or homeschool (homeschooled student must live in Noble County) who will be pursuing advanced education in emergency services involving fire, police, criminal justice and/or EMS.

Awards Per Year:

• 1 scholarship

Applicant High School:

• Central Noble, East Noble, Homeschooled, Wawasee, West Noble

Colleges:

• Any accredited college or university

Areas of Study:

• Criminal Justice, Emergency Medical Services, Emergency Services, Emergency services involving fire, police, criminal justice and/or EMS.

The U.S. Hillman Prize for Broadcast Journalism, awarded by the Sidney Hillman Foundation, recognizes outstanding journalism that serves the common good. Open to global journalists, the contest honors work accessible to U.S. audiences, with no entry limits per outlet. Winners receive a $5,000 honorarium and a certificate at a ceremony in New York City. This prestigious award highlights impactful stories across various media platforms, emphasizing the importance of journalism in addressing social issues.

Erin Marie Masling Memorial Scholarship

This scholarship encourages students who have the potential and desire to pursue a post-secondary education despite the effects of an ongoing medical condition or illness.

Number and Size of Awards

Number of recipients and award amounts vary; minimum award $500. Award paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters.

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

The Rod's Tire and Service Scholarship Fund, managed by the Central Kansas Community Foundation, offers $2,500 to assist graduating Marion County high school seniors pursuing higher education or vocational training. The foundation, established in 1994, focuses on enhancing community welfare through charitable giving and emphasizes support for students majoring in agricultural fields. This scholarship aims to empower local youth and strengthen the community by investing in their educational futures.

The Breast Cancer Community Education Grants, funded by the Oncology Nursing Foundation through AstraZeneca HealthCare Foundation, aim to enhance breast cancer awareness through nurse-led community education programs. Grants of up to $1,000 are available to ONS Chapters in the U.S., enabling them to implement impactful educational initiatives. Eligible activities must focus on community outreach and education, fostering a broader understanding of breast cancer.

The NCAA Postgraduate Scholarship for Winter Sports awards up to 126 scholarships of $10,000 annually to outstanding student-athletes who excel both academically and athletically. Eligible candidates are in their final year of NCAA competition and must have a minimum GPA of 3.2. The scholarships are available for men and women in various winter sports and are intended for use in accredited graduate programs, emphasizing the importance of academic achievement and community involvement.

The National Park Service (NPS) invites applications for Master Cooperative Agreements from participants in the Cooperative Ecosystem Studies Units (CESU) network across various regions. This initiative fosters collaboration among federal agencies, tribes, academic institutions, and conservation organizations to enhance resource stewardship. With 390 non-federal partners and 15 federal agencies, the CESU network supports interdisciplinary projects addressing diverse environmental and cultural heritage issues. Applications are continually accepted until the announcement's closing date.