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Best Franklin County Grants for Nonprofits in Mississippi

Looking for grants for 501(c)(3) nonprofit organizations working in Franklin County, Mississippi? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.18B

Total funding

$5K

Median grant

9,000+ grants
$3.18B total
$5K median

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8,999 Results based on applied filters

Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $100,000 - US $500,000
This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.
Biology Environmental Contamination & Pollution Neurological Diseases & Disorders +1 more

Limited Competition: Tribal Undergraduate and Graduate Research Training and Leadership Experiences (TURTLE) Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The TURTLE Program aims to empower Tribal Entities by fostering a skilled workforce in biomedical research. It supports undergraduate and graduate students in health research, ensuring they complete their degrees and transition into impactful careers. With phased awards, the program emphasizes effective training and mentoring, inviting eligible organizations to apply. Applications will undergo NIH's peer-review process, ensuring only the most meritorious proposals are funded, ultimately enhancing Tribal health research capabilities.
Education - Higher Education Workforce Preparation & Job Readiness Native American Services +1 more

Limited Competition: Tribal Institutional Review Board Establishment and Enhancement (TIRBEE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.
Epidemiology & Public Health Native American Services Health Disparities & Social Determinants of Health +1 more

Somatic Mosaicism across Human Tissues (SMaHT) Program: Tissue Procurement Center (R24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.
Biology Genetics & Genomics

Somatic Mosaicism across Human Tissues (SMaHT) Program: National Somatic Mosaicism Commons Data Analysis & Organizational Center (UM1 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance understanding of biological processes and disease mechanisms due to somatic mutations in human tissues. Since 2023, it has produced multi-omic datasets from various human tissues. The NIH plans to advance this initiative by establishing the National Somatic Mosaicism Commons Data Analysis & Organizational Center, which will oversee data management, develop analytical tools, and provide training to facilitate research and clinical applications.
Genetics & Genomics Computer Science & Engineering Emerging Technology Development

Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed) (363858)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to uncover biological processes and disease mechanisms influenced by somatic mutations. Since its inception in 2023, it has produced valuable multi-omic datasets from diverse human tissues. The upcoming Stage 2 Genome Characterization Centers will focus on understanding the impact of these mutations in both healthy and clinically significant samples, enhancing our knowledge of somatic mosaicism's role in human health and disease.
Biology Genetics & Genomics

A Year of STEM

American Library Association (ALA)
Association/Society
United States
US $5,000

In collaboration with Cummins Inc., the American Library Association (ALA) invites applications from U.S. public libraries to participate in A Year of STEM, 12 months of curated STEM programming to foster curiosity and STEM-mindedness in early childhood learners across the country. 

Twenty-five libraries will be chosen to participate in A Year of STEM, receiving professional development to prepare them for the project, copies of a newly created A Year of STEM programming guide developed by librarian advisors, a $5,000 programming stipend, four STEM kits (to be delivered quarterly), and support from ALA’s Public Programs Office staff throughout the project implementation period.

STEM / STEAM Education Library Services

The Penn Play Award

LR Penn
Corporate
United States
Unspecified amount

LRPenn.com is home to the novels, plays, and screenplays of LR Penn. His books specializes in Thrillers, Dramatic Comedies, and Film Noir. Thanks to the generous support of our sponsors, grants may be available to nonprofit theater companies in the United States with 501(c)(3) status that are staging productions of plays written by LR Penn.  

Theater

The Role of the Innate Immune System in the Pathogenesis of Type 1 Diabetes

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing Type 1 diabetes research by exploring the innate immune system's role in disease onset. This initiative aims to identify genetic and environmental factors contributing to Type 1 diabetes through multidisciplinary teams. By employing innovative methodologies, the program seeks to determine how immune responses affect pancreatic tissues, potentially leading to early detection and prevention strategies for at-risk individuals.
Genetics & Genomics Diabetes Immune System Diseases

Collaborative Centers in Children’s Environmental Health Research and Translation (P2C Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $750,000
The Collaborative Centers in Children’s Environmental Health Research and Translation program aims to establish a national network of research centers focused on improving children's health through innovative research and public health strategies. By fostering collaboration within the children’s environmental health community, these centers will lead the way in translating scientific findings into actionable practices, ensuring a healthier future for children while addressing emerging environmental threats.
Epidemiology & Public Health Environmental Health Children’s Health & Pediatrics

Immune Drivers of Autoimmune Disease

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Immune Drivers of Autoimmune Disease (IDAD) network, supported by NIAID, aims to uncover early triggers and mechanisms of autoimmunity to prevent disease. Key initiatives include developing predictive tools and biomarkers, fostering preclinical cohorts, and utilizing AI and big data. The network will leverage shared infrastructure for collaborative research, managed by the IDAD Network Coordinating Center, which ensures coordination and resource sharing among awardees. This initiative is crucial for advancing understanding and prevention of autoimmune diseases.
Immune System Diseases Preventative Healthcare Emerging Technology Development

NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) (363939)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $80,000
The NLM Grants for Scholarly Works in Biomedicine and Health (G13) program invites applications to support the creation of book-length manuscripts and scholarly works that are vital for U.S. health professionals and scientists. This initiative aims to foster critical reviews and analytical syntheses that enhance understanding of biomedical and public health challenges, ultimately contributing valuable resources for education, research, and clinical practice.
Health & Medicine Epidemiology & Public Health

LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The LAST MILE program, initiated by the NIAID, aims to enhance the implementation and effectiveness of HIV prevention and treatment strategies through real-world effectiveness trials. By fostering collaborations and focusing on diverse populations, this initiative seeks to translate clinical findings into practical applications. The program supports research across various disciplines, aligning with the NIH's mission to improve HIV/AIDS outcomes and address associated comorbidities. This multifaceted approach promises to bridge the gap between clinical trials and community-based interventions.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +1 more

Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is announcing a funding opportunity to support the Exceptional Longevity Data Management and Coordinating Center (EL DMCC). This initiative aims to enhance the management of large, diverse datasets and facilitate collaborative research across NIA projects. Core functions include data integration, AI/ML infrastructure development, and maintaining the ELITE Portal for secure data access. This NOFO encourages innovative approaches to longevity research, though applications are not currently being solicited.
Biology Genetics & Genomics Emerging Technology Development

Partnerships for Advancing Development of Diagnostics for Infectious Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance the development of diagnostic tests for infectious diseases through strategic partnerships between academia and industry. By fostering collaborations, NIAID seeks to overcome barriers to commercialization, ensuring promising diagnostics reach the market effectively. This initiative aligns with NIH's mission to advance innovative technologies that improve treatment and prevention strategies for infectious diseases, ultimately contributing to public health advancements.
Infectious & Parasitic Diseases Emerging Technology Development Allergies & Allergic Diseases

Mesara Family Foundation Grant

Mesara Family Foundation
Private
United States
Unspecified amount

About

Originally conceived by Dr Bruce Mesara in 1990 as a means to carry on his philanthropic efforts beyond his lifetime, the Mesara Family Foundation was re-envisioned by his two children Amy and Douglas in 2014, and received their 501(c)(3) status from the IRS in 2015. Amy and Douglas sought out the assistance of their cousins to build upon the charitable principals on their parents, aunts and uncles.

The foundation is headquartered in Kalamazoo Michigan.

Mission

The mission of the Mesara Family Foundation is to honor the philanthropic principles of the Mesara and Pauch families by supporting carefully selected organizations that share similar values. Our focus is to provide support toward education, conservation and other causes of special family interest where our funding will make a genuine difference.

Education Environmental Conservation

BJA FY 2026 John R. Justice (JRJ) Formula Grant Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BJA FY 2026 John R. Justice Formula Grant Program offers loan repayment assistance to local and state prosecutors and public defenders who commit to three years of service. Administered by state agencies, this program aims to alleviate the financial burden on legal professionals dedicated to public service. Applications are due by November 10, 2026, providing a crucial opportunity for eligible beneficiaries to secure support for their educational loans.
Crime & Justice Legal Services

Advancing coastal flood protection through public-private partnerships, innovative insurance products, and improved sediment management.

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $2,000,000
The National Oceanic and Atmospheric Administration (NOAA) is inviting proposals for projects that enhance coastal flood protection through public-private partnerships, innovative insurance products, and improved sediment management. This initiative aims to utilize natural infrastructure to bolster flood preparedness and resilience. Funding of up to $2,000,000 is available for selected projects, supporting research teams that collaborate with regional stakeholders. Proposals must be submitted via Grants.gov, ensuring accessibility to critical resources and information.
Habitat & Ecosystem Restoration Climate Change Resilience & Equity Coastal Conservation

OJJDP FY 2026 Second Chance Act Youth Reentry Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The OJJDP FY 2026 Second Chance Act Youth Reentry Program aims to provide critical support for moderate- to high-risk youth transitioning back into their communities after confinement. This funding opportunity encourages collaboration among state agencies, local governments, Tribes, and community organizations to deliver comprehensive reentry services and assist youth in overcoming challenges related to recidivism. Applications are due by November 9, 2026, at 8:59 p.m. ET.
Youth Services Crime & Justice Youth Development & Leadership

OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support aims to fortify a national network of 61 multiagency task forces dedicated to combating child sexual exploitation facilitated by technology. This funding opportunity enhances training, prevention, and outreach efforts while fostering collaboration among law enforcement entities. Applications are due in JustGrants by November 9, 2026, at 8:59 p.m. ET, ensuring timely support for critical initiatives to protect children.
Youth Services Crime & Justice Crime Victim Services +1 more

Strengthening Collaboration Between Tuberculosis Control Programs and Affiliated Partners in the United States.

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The CDC is offering funding to enhance collaboration among tuberculosis control programs and various partners in the U.S. This initiative aims to strengthen relationships with national TB control entities, federal agencies, academia, and community organizations. The goal is to promote health and quality of life by preventing, controlling, and eventually eliminating tuberculosis in the United States, building on previous funding opportunities.
Epidemiology & Public Health Infectious & Parasitic Diseases Preventative Healthcare +1 more

Advanced Rehabilitation Research Training (ARRT) Program - Employment (363964)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program aims to enhance the research capabilities of individuals with advanced degrees, focusing on disability and rehabilitation research related to employment outcomes. Funded by the US HHS Administration for Community Living, this grant offers a 36-month project period, supporting multidisciplinary training for researchers, including those with disabilities, to contribute to high-quality research in the field.
Disability Care & Services Medical Rehabilitation Employment Services +1 more

Advanced Rehabilitation Research Training (ARRT) Program - Health and Function (363965)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the capabilities of individuals with advanced degrees in conducting high-quality research focused on health and function outcomes for people with disabilities. The program offers advanced training opportunities over a 36-month period, specifically targeting rehabilitation researchers, including those with disabilities, to foster multidisciplinary approaches in disability and rehabilitation research.
Medical Rehabilitation Medical Education & Professional Training Disability Rights & Justice

Small Business Innovation Research Program (SBIR) Phase II (363967)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $280,000 - US $287,500
The Small Business Innovation Research Program (SBIR) Phase II aims to enhance technological innovation in the private sector, focusing on improving the lives of individuals with disabilities through research and development. Administered by the US HHS Administration for Community Living, this program supports small businesses in addressing the needs of these individuals. Grants are available for a 24-month project period, allowing projects to expand upon Phase I results to achieve greater commercial application and societal impact.
Disability Care & Services Medical Rehabilitation Emerging Technology Development +1 more

Small Business Innovation Research (SBIR) program, Phase I (363966)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $95,000 - US $100,000
The Small Business Innovation Research (SBIR) program, Phase I, aims to stimulate technological innovation in the private sector, enhancing the role of small businesses in meeting Federal research needs. Specifically, ACL's SBIR program focuses on improving the lives of individuals with disabilities through research and development products. The initiative includes 11 grants with a 6-month project period to assess the feasibility of innovative concepts, contributing to economic and social benefits.
Disability Care & Services Emerging Technology Development Business Development

BJA FY 2026 National Center for Veterans Justice

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $4,000,000
The BJA FY 2026 National Center for Veterans Justice aims to enhance support for veterans in the criminal justice system. By providing specialized training and resources to law enforcement and service providers, the center will address critical gaps in veteran identification and coordination among agencies. This initiative seeks to improve outcomes for veterans experiencing issues like PTSD and military sexual trauma, ultimately strengthening public safety and ensuring effective responses to their unique needs.
Military & Veterans Services Mental Health & Psychiatric Diseases Crime & Justice

BJA FY26 Paul Coverdell Forensic Science Improvement - Formula Grants Program

US Department of Justice: National Institute of Justice (NIJ)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BJA FY26 Paul Coverdell Forensic Science Improvement - Formula Grants Program supports state agencies in enhancing forensic science capabilities. The program aims to improve public safety by funding initiatives that strengthen forensic science and support law enforcement efforts. Eligible applicants can submit their full applications through JustGrants by November 6, 2026. This funding is crucial for addressing ongoing challenges in the justice system, including violent crime and public safety concerns.
Crime & Justice Community / Public Safety

Franklin County Grants for Nonprofits Highlights

Looking for Franklin County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Franklin County grants recommended for your specific programs in Mississippi.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in Mississippi

Average Grant Size

What's the typical amount funded for Mississippi?

Grants are most commonly $94,687.

$94,687

Total Number of Grants

What's the total number of grants in Franklin County Grants for Nonprofits year over year?

In 2024, funders in Mississippi awarded a total of 8,599 grants.

2022 7,983

2023 8,165

2024 8,599

Top Grant Focus Areas

Among all the Franklin County Grants for Nonprofits given out in Mississippi, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Franklin County Grants for Nonprofits changing over time?

Funding has increased by 2.35%.

2022 $634,985,073

2023 $789,259,908
24.30%

2024 $807,768,252
2.35%

Mississippi Counties That Receive the Most Funding

How does grant funding vary by county?

Oktibbeha County, Hinds County, and Lafayette County receive the most funding.

County Total Grant Funding in 2024
Oktibbeha County $274,520,115
Hinds County $230,593,243
Lafayette County $93,085,023
Harrison County $41,719,363
Madison County $39,767,542