Best Operating Grants for Nonprofits in Iowa

The Emily Hall Tremaine Exhibition Award, established in 1998, supports innovative, thematic exhibitions that present contemporary art within unconventional frameworks. It fosters creativity by offering funding up to $200,000 for curators partnering with non-profit spaces. The award encourages exploration of critical ideas, emphasizing intellectual quality and public impact. Eligible applicants include established curators and institutions, aiming to promote artistic expression while enhancing community engagement and discourse through diverse projects.

The Richard I. Stessel Waste Management Award, presented annually by the Air & Waste Management Association, honors outstanding achievements in waste management. This prestigious award acknowledges individuals and organizations for their significant contributions to the science and practice of waste management, including technological advancements, waste regulation, and educational excellence. Named after Professor Richard I. Stessel, the award promotes innovative solutions for environmental sustainability, encouraging professionals to serve as role models in the field.

The Antoinette Lierman Medlin Scholarship, administered by the Geological Society of America, supports graduate students in coal science. It offers two awards: $2000 for laboratory research and $1500 for fieldwork. This scholarship aims to recognize and assist students in completing their research projects successfully. Contributions from personal and corporate sponsors help sustain this valuable fund, encouraging commitment to advancing knowledge in energy geology.

The BJA FY 2026 Emmett Till Unsolved Civil Rights Crimes Act Program aims to assist state, local, and tribal law enforcement agencies in investigating and prosecuting civil rights offenses that resulted in death before December 31, 1979. This funding opportunity is part of the DOJ's broader commitment to enhance public safety, protect civil rights, and ensure justice for victims of violent crime. Applications are due on November 20, 2026.

The Solidaire Network's Janisha R. Gabriel Movement Protection Fund supports frontline organizers facing security threats while fostering long-term safety. With $7.9 million allocated, the fund aids groups working towards racial, climate, gender, and reproductive justice. Despite a pause on new applications due to high demand, the fund remains committed to resourcing movement partners and addressing the disproportionate targeting of marginalized leaders amidst rising aggression from right-wing forces.

Across the United States, small and micro businesses (SMBs) play a critical role in driving economic opportunity, job creation, and community prosperity. Yet many entrepreneurs continue to face challenges accessing the training, resources, and support needed to grow and remain competitive in an evolving economy. To help address these needs, Visa Foundation is committing $2M to launch an open-call grant program that will support nonprofit Entrepreneurial Support Organizations (ESOs) that provide direct services to SMBs. Through this program, Visa Foundation aims to strengthen the capacity of high-impact organizations that help small businesses build greater resilience, expand economic opportunity, and contribute to thriving local economies. 

Kickstart Your Project with a Mini-Grant

At H2O for Life, we never want finances to be a barrier to participating in a service project. The H2O for Life Mini-Grants are meant to be a supportive resource for teachers and students who want to kick-start their projects with us. Mini-grants of up to $500 will be awarded to support teachers and students with the necessary funds for their service-learning programs.

Our Mission

H2O for Life offers a service-learning opportunity designed to engage, educate and inspire youth to take action to solve the global water crisis by raising awareness and funds to support implementation of water, sanitation and hygiene education projects for global partner schools.

Since 2007, nearly 1 million students from H2O for Life schools have supported water, sanitation, and hygiene education projects for partner schools in the developing world.

What is H2O for Life doing to address the global water crisis?

H2O for Life’s service-learning opportunities are designed to engage, educate, and inspire youth to become global citizens. Our innovative school-to-school approach helps young people develop a concern for others by taking a major global crisis and scaling it down to a manageable size — one water project in the developing world.

Through the service-learning opportunity we provide, students learn that they can make a tangible difference for the students in their partner school.

The AHRF Birtman Grant provides up to $75,000 for one year of research focused on hearing and balance disorders related to the inner ear. This grant encourages both basic and clinical studies, covering direct costs such as staff salaries and research equipment. Applicants must hold relevant advanced degrees and be affiliated with a U.S. university or hospital. An alternative budget option of $50,000 is available, enhancing eligibility for Regular grants if not awarded the Birtman Grant.

The Genentech Foundation supports innovative projects that address systemic inequities in healthcare. They fund tax-exempt organizations, including public charities and governmental entities, located in the U.S. Grant requests must be submitted at least 60 days before the project start date. Notably, projects must align with Genentech's commitment to advancing health equity and diversity in the medical workforce. Applications for funding will be accepted starting January 2, 2026, after a temporary closure.

The SCICF: Lucas County Grants aim to enhance the quality of life in Lucas County by funding nonprofits and encouraging community contributions. Eligible applicants include 501(c)(3) organizations and government units, focusing on areas such as arts, education, and health. The foundation prioritizes projects that foster societal benefit while avoiding support for existing debts and operational costs. This initiative by the South Central Iowa Community Foundation emphasizes impactful community engagement through strategic funding.

The Technical Assistance and Training Grant Program by the USDA's Rural Utilities Service provides funding for essential technical assistance and training aimed at resolving water and waste management issues. This program supports applicants in preparing loan and grant applications, enhancing the operational efficiency of water systems, and ensuring compliance with best practices in facility management. However, grant funds cannot be used for duplicating existing services or for capital expenditures.

The 1Fur1 Foundation Grant supports U.S.-based 501(c)(3) charities that engage in animal-assisted programs. Eligible organizations can apply for grants ranging from $500 to $7,500 to support Animal Assisted Therapy, Activity, and Service Dog programs. The foundation focuses on charities that align with its mission and does not fund individual requests, for-profit businesses, or initiatives that promote animal cruelty. Applications are reviewed within 90 days.

Jazz Road Tours Grants provide financial support for emerging and mid-career jazz artists to develop tours across communities in the U.S. Grants up to $15,000 facilitate three-to-six site tours, focusing on underserved areas. This program, funded by the Doris Duke Charitable Foundation and the Mellon Foundation, aims to enhance artists' income opportunities while promoting jazz in diverse venues. Applications are encouraged from individual artists, with deadlines throughout 2024 and 2025 for various tour periods.

The Towsley Foundation Grants support initiatives that enhance community welfare and sustainability, focusing on diverse fields such as education, health, and the arts within Michigan. With a commitment to effective philanthropy, the foundation prioritizes projects that demonstrate creativity and strategic impact. Eligible organizations must operate in Michigan and adhere to specific funding guidelines, fostering financial sustainability. Grants are allocated based on project merit and organizational capacity, reinforcing the foundation's mission to improve lives through thoughtful partnerships.

The Simply Organic Giving Fund Grant aims to combat food insecurity in the U.S. and Canada by providing access to nutrient-dense organic food for those in need. Since its inception, the fund has supported various initiatives, including training centers for organic agriculture and community food projects. With a focus on sustainable practices, the grant program seeks to empower communities and improve food access for vulnerable populations, ensuring that healthy, organic options are available to all.

Ignite Your Innovation & Entrepreneurship Ecosystem

Lead the future of innovation at your higher education institution with the Ecosystem Futures Fellowship. This fellowship is an evolution of our Course & Program Grants that focuses on scalable science, technology, engineering, and math (STEM) innovation and entrepreneurship (I&E) ecosystem solutions through the lens of environmental and social sustainability and inclusive innovation. This program offers professional development, immersive learning experiences, and a supportive community of leaders. It enhances the role of faculty and higher education leaders as ecosystem builders in partnership with industry and government.

VentureWell Ecosystem Futures Fellowship

The Ecosystem Futures Fellowship is a one-year program that aims to strengthen campus innovation and entrepreneurship. This fellowship enhances both in-class and out-of-class student engagement and institutional culture by growing ecosystem networks. Teams of two will receive $30,000 in funding—a $10,000 award and $5,000 in travel stipends for each fellow—and 12 months of immersive programming and communities of practice.

The Ecosystem Futures Fellowship is a one-year experience that supports higher education leaders in advancing science, technology, engineering, and math (STEM) innovation and entrepreneurship (I&E) ecosystem growth centered on environmental and social sustainability and inclusive innovation.

What types of projects are eligible?

Projects should focus on STEM I&E ecosystem expansion, addressing significant social, health, or environmental challenges. Your STEM I&E ecosystem growth goals might align well with the fellowship if they are similar to one of the following:

• Building out a degree pathway that incorporates I&E into STEM disciplines
• Creating or revising courses that focus on STEM I&E through a social and environmental sustainability lens—these should be courses that make connections to I&E beyond the course in order to provide more robust I&E opportunities to a diverse population of students (community-engaged learning, internships, industry partnerships, etc.)
• Connecting existing courses to campus and off-campus extracurricular and co-curricular activities
• Designing new extracurricular and co-curricular I&E activities that connect to community partners
• Working with government, industry, or other community collaborators to expand STEM I&E activities on and off campus for students and other campus collaborators
• Working with administration on campus to change policies or systems that hinder STEM I&E activities on campus (promotion and tenure requirements, tech transfer opportunities, IP policies, etc.)
• Breaking down silos on campus in order to grow connections between disciplines and learning opportunities beyond the classroom
• Strengthening research translation and innovation development opportunities that work to solve the world’s most difficult problems

What support is provided besides funding?

• Mentorship from experienced industry experts.
• Access to a resource library and a collaborative network of STEM educators and students.
• Participation in on-campus immersive experiences, communities of practice, and VentureWell’s annual conferences.

History of AHTF

In the beginning, AHTF’s founders recognized that hand therapy was needed and worked; however, research to support that belief was limited.

The American Society of Hand Therapists (ASHT) was founded in 1977. By the 1980’s hand therapy was growing fast and clinical knowledge of hand care lead to remarkable improvements in the treatment of diseased and injured hands. With improvements, however, came the increased need to further substantiate hand therapy practice.

Tri-Alliance Grant Honoring ASHT Founders

Purpose

To fund impactful research in all levels of experimental quantitative research, including systematic reviews, as well as qualitative research. The AHTF has the responsibility of verifying the appropriateness of the proposed research.

Types of Studies

Grant proposals are accepted for research within any domain of hand therapy. Randomized or experimental study designs, including quantitative, mixed methods, or qualitative designs that aim to advance the clinical practice of hand and upper extremity rehabilitation. Ideally, applications should target categories of research identified as part of the current AHTF research priorities.

History of AHTF

In the beginning, AHTF’s founders recognized that hand therapy was needed and worked; however, research to support that belief was limited.

The American Society of Hand Therapists (ASHT) was founded in 1977. By the 1980’s hand therapy was growing fast and clinical knowledge of hand care lead to remarkable improvements in the treatment of diseased and injured hands. With improvements, however, came the increased need to further substantiate hand therapy practice.

Burkhalter New Investigator Grant for Clinical Research in Hand & Upper Limb Rehabilitation

Purpose

In 1993, the AHTF established a grant in honor of Dr. William Burkhalter (1928-1992), a long-time advocate and promoter of hand therapy. The purpose of the award is to support scientific clinical research in the field of hand and upper limb rehabilitation.

Types of Studies

Experimental, non-experimental, pilot studies, quasi-experimental, measurement, or qualitative studies designed to advance the clinical practice of hand and upper extremity rehabilitation in categories identified by the AHTF research priorities will be considered.

History of AHTF

In the beginning, AHTF’s founders recognized that hand therapy was needed and worked; however, research to support that belief was limited.

The American Society of Hand Therapists (ASHT) was founded in 1977. By the 1980’s hand therapy was growing fast and clinical knowledge of hand care lead to remarkable improvements in the treatment of diseased and injured hands. With improvements, however, came the increased need to further substantiate hand therapy practice.

Judy Bell-Krotoski "Grab the Evidence" Grant

Purpose

In 2003, AHTF awarded the first “Grab the Future” Grant. This name was changed in 2005, in response to the growing need to fund basic research science and evidence-based studies in hand and upper limb rehabilitation.

The purpose of the award as designed is to serve as a catalyst for a skilled researcher and/or research team to develop their role as principal investigators and to provide seed money for procurement of larger external funding. 

Types of Studies

Experimental studies, pilot studies, or systematic reviews/meta-analyses which support the evidence of hand and upper extremity rehabilitation in the diagnostic categories identified by the AHTF research priorities or by the specific donor’s research priorities will be considered.

The Parkinson's Foundation offers Community Grants to support impactful programs for people with Parkinson's disease across the U.S. With over $5 million awarded in the last three years, the Foundation aims to enhance health, wellness, and education. Eligible applicants include local non-profits and healthcare facilities focusing on mental health, care partner support, and exercise programs tailored for PD. This initiative promotes diversity, equity, and inclusion in service delivery.

The National Institute of Allergy and Infectious Diseases (NIAID) is launching the Centers for Research on Neglected Infectious Diseases (CReNIDs) to enhance research on neglected infectious diseases (NIDs). This initiative aims to tackle substantial health challenges posed by communicable viral, bacterial, and parasitic infections, especially in endemic regions. By fostering multidisciplinary research and sustainable local capacities, the program seeks to improve health outcomes and mitigate the spread of these diseases, ultimately safeguarding public health in the U.S. and globally.

Iowa Workforce Grant & Incentive Program

This program provides up to $2,000 in grant funding per semester for students enrolled full-time in eligible undergraduate programs of study at an eligible school. Students enrolled part-time can qualify for prorated award amounts.

Award Amount and Limits

The statutory maximum award is $2,000 per semester for full-time students. However, the maximum award for an academic year may be less depending on the funding available and the number of projected recipients. 

The funded maximum 2026-27 award is $1,125 per semester for full-time students. Recipients can receive up to four full-time grant awards or the part-time equivalent. Part-time students may be eligible for adjusted amounts. Awards are available during the fall and spring semesters.

Workforce Incentive Program

Students who complete their undergraduate degree or teacher preparation program in the same academic year in which they receive a Workforce Grant can qualify for an incentive payment of up to $2,000 if they meet the following requirements:

Within six months of completing the eligible program, begin full-time work in a high-demand job in Iowa AND apply for the incentive payment.  

Directory of high-demand jobs 

The OJJDP FY 2026 Opioid Affected Youth Initiative provides funding to support states and localities in combating violent crime and overdose deaths. This initiative aims to enhance prevention, intervention, and treatment strategies for children, youth, and families impacted by substance use disorders. Collaboration among law enforcement, educational institutions, and community organizations is essential to effectively address the needs of at-risk populations and those already involved in the child welfare and justice systems.

The NIJ FY 2026 Research and Evaluation on Human Trafficking funding opportunity aims to support comprehensive research and evaluation projects. It focuses on preventing human trafficking, assessing the impact of federal policies, and enhancing services for victims. This initiative, led by the National Institute of Justice in partnership with the Office for Victims of Crime, seeks to generate insights that can inform better responses to human trafficking in the U.S.

About The Glaucoma Foundation

The Glaucoma Foundation is dedicated to improving the lives of people with glaucoma. The Foundation works to encourage and support basic and applied research in glaucoma with a goal of preserving and restoring vision. We strive to be an important resource to help patients, their families, and at-risk individuals to manage their glaucoma through education and outreach.

About Research to Prevent Blindness

The mission of Research to Prevent Blindness (RPB) is to preserve and restore vision by supporting research to develop treatments, preventives and cures for all conditions that damage and destroy sight. Since it was founded 60 years ago, in 1960, RPB has channeled more than $383 million into eye research. As a result, RPB has been identified with nearly every major breakthrough in vision research in that time.

The Glaucoma Foundation (TGF) and Research to Prevent Blindness (RPB) partner annually to provide a grant aimed at supporting women and under-represented racial and ethnic minority researchers in the pursuit of glaucoma research.

The TGF (sponsored by Patricia Hill) / RPB Fellowships in Glaucoma provide one-year $10,000 fellowships focused on substantive glaucoma research, including investigation into the etiology, diagnosis and/or treatment of glaucoma, to current ophthalmology fellows with an MD, MD/PhD, PhD or other relevant degree.

The Glaucoma Foundation: Advancing the Treatment of Glaucoma

The Glaucoma Foundation (TGF) is dedicated to accelerating breakthrough glaucoma research and helping move promising discoveries toward patients. By supporting innovative, next-generation research and connecting leading scientists and clinicians, TGF drives progress toward better understanding, diagnosis, and treatment of glaucoma, with the ultimate goal of finding a cure.

Exfoliation Syndrome and Exfoliation Glaucoma, Pressure Independent Mechanisms of Glaucoma, Neuroprotection, and the Genetics of Glaucomas that affect people under the age of 40

The Glaucoma Foundation offers grants to researchers striving to improve the lives of glaucoma patients through novel innovations and scientific advances. The areas of current focus for TGF’s Grant Research program are Exfoliation Syndrome and Exfoliation Glaucoma, Pressure Independent Mechanisms of Glaucoma, Neuroprotection, and Genetics of Glaucomas that affect people under the age of 40 years. Examples of research that may be considered range from basic science to clinical interventions, such as genetics and genomic medicine, disease modeling, assessment of ocular perfusion, artificial intelligence, and clinical research. A priority will be given to novel proposals with a viable study hypothesis leading to impactful results that are fundable at the NIH level. Initial grant funding for one year is for up to $75,000; a grantee is permitted to apply for a grant renewal of up to $75,000. A renewal grant is a one-year grant based on research findings from the initial research.

The Conchologists of America (COA) offers grants up to $2,500 for research on recent or fossil mollusks. This funding is available for projects that explore malacological topics, ensuring that the proposed work is self-contained and capable of addressing specific research questions. While COA encourages applications for amounts less than the maximum, funding is not typically awarded to high school students or for institutional overhead. This initiative supports a wide range of malacological disciplines.