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Best Operating Grants for Nonprofits in Iowa

Find the perfect Operating grants for nonprofits in Iowa on Instrumentl. 10,000+ Operating grants for nonprofits in Iowa in the United States.

10,000+

Available grants

$2.56B

Total funding

$5K

Median grant

10,000+ grants
$2.56B total
$5K median

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9,583 Results based on applied filters

TMCity Foundation: Research Grant

TMCity Foundation
Private
United States
US $25,000 - US $250,000
The TMCity Foundation Grant supports innovative research in neurocognitive healthcare, with funding ranging from $25,000 to $250,000. This grant aims to address critical challenges in mental health by fostering cutting-edge research and transformative technologies. Applicants, preferably 501(c)(3) organizations, can submit letters of inquiry on a rolling basis, with a focus on projects based in Southern California and the Greater Boston area. The Foundation is committed to catalyzing advancements in understanding the brain and delivering effective treatments.
Brain Injuries Cognitive Science Neuroscience +3 more

Presbyterian Church (U.S.A.): Undergraduate Scholarships

Presbyterian Mission Agency
Private
United States
Up to US $6,000
The Presbyterian Church (U.S.A.) offers financial support through undergraduate scholarships for up to 100 eligible college students each year. Applicants must be members of PC(USA) pursuing their first associates or bachelor's degree at an accredited institution in the U.S. during the 2025-2026 academic year. This initiative aims to assist students in overcoming financial barriers to education while fostering a commitment to service within their communities.
Academic Scholarship Programs Presbyterianism Black American Services +2 more

Best Buy Teen Tech Center - Mini Tech Skills Workshop Grant

Best Buy Foundation
Private
Alameda County, California, Albemarle County, Virginia +47 more
Up to US $24,999
The Best Buy Teen Tech Center is offering a Mini Tech Skills Workshop Grant to support local and national non-profits in providing STEAM skills workshops for youth aged 13-19. These workshops, which include topics such as coding, filmmaking, and robotics, aim to enhance technical skills and career exploration. Funding can reach up to $24,999, with a focus on hands-on, facilitator-led experiences, and additional programming opportunities may be considered.
After School / Summer Educational Programs Youth Services Workforce Preparation & Job Readiness +2 more

NCAA Postgraduate Scholarship - Fall Sports

National Collegiate Athletic Association
Private
Canada, Puerto Rico +2 more
US $7,000
The NCAA Postgraduate Scholarship for Fall Sports offers up to 126 scholarships annually, valued at $10,000 each, to student-athletes who excel academically and athletically. Eligible candidates must be in their final year of intercollegiate competition and maintain a minimum GPA of 3.20. Scholarships are awarded three times a year, with 21 available for men and 21 for women across various sports. This initiative promotes graduate education and recognizes the achievements of outstanding student-athletes.
Sports & Athletics Equestrian Sports Duathlons & Triathlons +2 more

NEA Federal Rescue Implementation Network Grant

National Education Association Staff Organization
Private
United States
Up to US $100,000
The NEA Federal Rescue Implementation Network Grant provides up to $100,000 per year for two years to state affiliates for hiring a coordinator to implement the American Rescue Plan in support of public education. This funding is specifically for backfilling a position that must remain filled for at least ninety days, ensuring effective oversight of federal recovery initiatives within the affiliate.
Education - K through 12 Teacher Development & Training After School / Summer Educational Programs +3 more

The American Action Fund for Blind Children and Adults Scholarship

National Federation Of The Blind Inc
Private
District of Columbia, Puerto Rico +1 more
US $10,000

About Us

Who We Are

The National Federation of the Blind is the oldest and largest nationwide organization of blind Americans. Founded in 1940 and currently headquartered in Baltimore, the NFB consists of affiliates, chapters, and divisions in all fifty states, Washington, DC, and Puerto Rico.

What We Do

Through our network of blind members, we coordinate many programs, services, and resources to defend the rights of blind Americans, provide information and support to blind children and adults, and build a community that creates a future full of opportunities.

What We Believe

We are the only organization that believes in the full capacity of blind people and has the power to transform our dreams into reality. We believe in blind people because we are blind people—from our democratically elected leaders to our diverse nationwide membership.

Scholarship Program

Thanks to our generous partners, there are thirty $10,000 merit-based scholarships currently available. All scholarships are awarded on the basis of academic excellence, community service, and leadership. The finalists are announced every spring. They then attend our national convention in July when the winners of each individual scholarship are selected. 

The American Action Fund for Blind Children and Adults Scholarship

For more than 100 years the American Action Fund for Blind Children and Adults has strived to improve the lives of blind and Deafblind children and adults. Best known for annually producing and gifting Braille Calendars, sponsoring the free Braille books for blind children program, and administering the Braille Readers are Leaders contest, the American Action Fund leads in promoting Braille literacy. The American Action Fund is proud to award this scholarship to a deserving and talented blind person. 

Vision Impairment Care & Services Hearing Impairment Care & Services Literacy +3 more

Nancy Talbot Postdoctoral Research Fellowship

The American Occupational Therapy Foundation Inc
Private
United States
US $30,000
The Nancy Talbot Postdoctoral Research Fellowship, established by the American Occupational Therapy Foundation, offers $30,000 for one year to support postdoctoral research in occupational therapy. This fellowship aims to enhance diversity in the field by funding individuals from underrepresented racial and ethnic groups, as identified by the NSF. Eligible candidates must hold an OT degree or relevant doctorate, have a mentor, and conduct research at a U.S. academic institution.
Physical Therapy Occupational Therapy Medical Education & Professional Training +4 more

NRF Foundation: Bright Futures Scholarship

NRF Foundation
Private
United States
Up to US $1,200
The NRF Foundation Bright Futures Scholarship provides a unique opportunity for undergraduate students to attend the 2026 NRF Foundation Student Program in New York City at no cost. This need-based scholarship allows students to explore career paths in the retail industry, meet leading recruiters, and gain insights from industry executives. Eligible students can receive free travel and accommodation for this enriching experience, which takes place from January 8-11, 2026.
Education - Higher Education Workforce Preparation & Job Readiness Academic Scholarship Programs +2 more

PennHOSA Foundation Scholarship

The Foundation for Enhancing Communities
Private
United States
US $2,500
The PennHOSA Foundation Scholarship promotes healthcare careers by providing scholarships to HOSA student members in Pennsylvania. It aims to enhance compassionate care delivery and community needs. Additionally, the Helen Heidelbaugh Aspire Award is given to one student focusing on community service. Eligible applicants must be HOSA members and enrolled in accredited healthcare programs, demonstrating financial need. This scholarship is a one-time award, reinforcing the commitment to future healthcare professionals.
Education - Higher Education Volunteerism & Philanthropy Medical Education & Professional Training +3 more

Multiple Sclerosis (MS) Health Equity Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $3,000 - US $8,000

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS) health equity

Help with healthcare costs for multiple sclerosis (health equity)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

Health Care Access & Delivery Multiple Sclerosis Chronic Illnesses +1 more

Cohort Studies of HIV/AIDS and Substance Use (U01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.
HIV / AIDS Addiction & Substance Use Disorders

Tick-borne Pathogen Award

Bay Area Lyme Foundation
Private
United States
US $150,000
The Tick-borne Pathogen Award, sponsored by Bay Area Lyme Foundation, offers $150,000 to support innovative research on non-Borrelia tick-borne pathogens. This grant aims to attract scientific talent to explore co-infections with Lyme disease and other related infections. Eligible candidates include researchers from academia or the private sector at the post-doctoral level or higher, with a focus on improving diagnostics and therapies for tick-borne diseases. Applications must present a viable proof-of-concept project.
Microbiology Infectious & Parasitic Diseases Lyme Disease +1 more

Boone County Community Foundation Grants: Simple Grant

Boone County Community Foundation, IA
Association/Society
Boone County, Iowa
Up to US $3,000

Boone County Community Foundation

The Boone County Community Foundation was formed in 2005 to coordinate and provide philanthropic support for community betterment projects in Boone County. The foundation is made up of community minded individuals who have the ability to assess community needs, implement asset development, evaluate area grant applications, encourage partnerships and initiate activities to enhance Boone County.

Mission: The Boone County Community Foundation is a charitable foundation created by and for local citizens to improve the quality of life right here in our communities. We are here to help donors make a positive, local impact by offering a variety of giving tools to help people achieve their charitable giving goals and do good work in our communities that lasts forever.

Grants

Each year the foundation makes grant awards to worthwhile projects located in the county that are identified through a community grants application process. Our foundation’s areas of emphasis include: arts & culture, community affairs & development, education, environmental protection, health, historic preservation and human services.

Three types of grants based on grant amount: Simple Grant; Standard Grant and Impact Grant

Simple Grant

$3,000 and under

Environmental Conservation Educational Access & Equity Arts / Culture Access & Participation +4 more

Indigo Oak Fund: Grant for Women & Children's Issues

Vance R and Colleen H Andrus Family Foundation
Private
United States
Unspecified amount
The Indigo Oak Fund, a Colorado-based private foundation, focuses on empowering women and children through various initiatives. By funding organizations that address issues such as domestic abuse, food insecurity, and gender equity, the Fund aims to improve lives and foster lifelong learning. Their mission emphasizes recognizing individual potential and ensuring equal opportunity for all, making a significant impact in communities across Colorado and the Bay Area.
Women & Girl Services Women's Rights & Equality Women's Health +4 more

Rural Maternity and Obstetrics Management Strategies Program (363582)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.
Reproductive Health Women's Health Maternal And Perinatal Health +1 more

Furer-Barag-Wolf Post 126 Jewish War Veterans Scholarship Award

Jewish Community Foundation
Private
United States
Unspecified amount
The Furer-Barag-Wolf Post 126 Jewish War Veterans Scholarship Award supports children or grandchildren of JWV Post 126 members, providing merit-based assistance for college or vocational education. Eligible applicants must reside in specific counties in New Jersey or be related to a JWV member. The scholarship covers tuition, books, and living expenses and is open for reapplication annually. This initiative by the Jewish Community Foundation fosters educational opportunities for deserving students.
Education - Higher Education Military & Veterans Services Academic Scholarship Programs +6 more

Avant Garde Award for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $350,000 - US $700,000
The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.
HIV / AIDS Addiction & Substance Use Disorders

Dr. Carol J. Chrisman Nursing Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Dr. Carol J. Chrisman Nursing Scholarship, offered by the Ashland County Community Foundation, supports registered nurses and nursing students from Ashland County pursuing advanced degrees at Ashland University. This scholarship honors Dr. Chrisman's legacy in nursing and community health, encouraging local nurses to further their education. Eligible applicants include full-time nursing students and those employed in public health within the area, with prior recipients allowed to reapply once.
Education - Higher Education Career / College Preparation Education - High School +3 more

Truist Foundation: Inspire Awards

Truist Foundation Inc
Private
United States
US $10,000 - US $250,000

Truist Foundation

The Truist Foundation is committed to Truist Financial Corporation's (NYSE: TFC) purpose to inspire and build better lives and communities. Established in 2020, the foundation makes strategic investments in nonprofit organizations to help ensure the communities it serves have more opportunities for a better quality of life. The Truist Foundation's grants and activities focus on building career pathways to economic mobility and strengthening small businesses.

Inspire Awards

This year’s Inspire Awards seeks nonprofits supporting the career navigation and workforce development needs of workers across the United States. The challenge seeks applications that help individuals gain the skills, guidance, and support needed to access quality jobs, advance in their careers, and build long-term stability in an evolving world of work.

2026 Truist Foundation Inspire Awards Challenge Question

How are nonprofits providing innovative direct services, training programs, and career navigation supports for adult workers in the age of AI?

Challenge Dimensions

Nonprofit organizations have long been critical advocates and service providers for workers in the United States. Nonprofits provide workers necessary upskilling opportunities, AI literacy training, career navigation support, and wraparound services in conjunction with career pathways programming. All necessary for the modern workforce. Meeting the moment, Truist Foundation and MIT Solve want to hear the ways in which nonprofits headquartered in the Truist operating footprint are providing innovative career pathway programming in the age of AI. Although solutions don’t need to focus on generative AI specifically, teams should demonstrate how their career pathways programming align with the following dimensions:

  • Training and Upskilling Programs – Providing holistic, accessible programming that equips workers with essential skills, industry-validated credentials, and technical literacy for the modern workplace.
  • AI Readiness and Literacy – Offering high-quality training that helps workers understand generative AI and agentic technologies as augmented intelligence tools, helping to build practical skills like effective prompting, domain expertise application, and ethical use.
  • Additional Wraparound Services and Basic Needs Support – Supporting unemployed and underemployed workers on their journey to economic mobility through comprehensive, integrated resources including childcare, transportation support, mentorship, mental health services, benefits navigation, and more.
  • Career Navigation in the AI Economy – Enabling workers to navigate career choices with clarity and confidence by providing accessible information about how AI is reshaping job roles and industries, facilitating informed decisions about high-quality career trajectories that align with individual circumstances, and connecting workers to industry-validated credentials or trainings.

Here are the grants for this challenge

  • First place: $250,000
  • Second place: $150,000
  • Runners-up: $25,000
  • Audience favorite: $75,000

Business Development Financial Literacy Entrepreneurship +4 more

AWWA Scholarships Program - Mueller Water Products Continuing Education Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $5,000
The AWWA Scholarships Program, led by the American Water Works Association, aims to support the future of the water industry by investing in students. The Mueller Water Products Continuing Education Scholarship awards $5,000 to an undergraduate student employed by a water utility, emphasizing the importance of practical experience in education. This scholarship not only aids financial needs but also encourages students to pursue careers in water supply, fostering growth in this vital sector.
Water Resource Management Academic Scholarship Programs

AWWA Scholarship Program - Veolia Water Technologies & Solutions Vernon D. Lucy III Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $5,000
The AWWA Scholarship Program, specifically the Veolia Water Technologies & Solutions Vernon D. Lucy III Scholarship, offers a $5000 award to undergraduate students pursuing careers in the water sector. Established by the American Water Works Association, this scholarship honors the mentorship of Vernon D. Lucy III and aims to support the next generation of water industry professionals. Eligible candidates must demonstrate interest in water-related fields, underscoring AWWA's commitment to fostering future leaders.
Water Resource Management Academic Scholarship Programs

Dementia CAReS Grants for American Indian and Alaska Native Communities

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
US $750,000
The Dementia CAReS Grants aim to enhance the lives of American Indian and Alaska Native communities affected by dementia. By providing funding, training, and support, this initiative focuses on developing actionable strategies within Tribal and Urban Indian settings. Key activities include establishing a network of dementia champions and promoting local best practices. The goal is to empower communities to improve dementia care and outcomes through collaborative efforts and innovative approaches.
Indigenous Health Systems Native American Services Indigenous Services +1 more

COPIC Medical Foundation Grants

Copic Medical Foundation
Private
United States
Unspecified amount
The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.
Medical Education & Professional Training Health Information Technology Patient Safety +1 more

The Steven Scott Quinn Scholarship Fund

Stark Community Foundation
Private
United States
More than US $500
The Steven Scott Quinn Scholarship Fund, established by the Stark Community Foundation, aims to support Stark County, Ohio residents pursuing higher education in fields such as culinary arts, hospitality, nursing, nutrition, physical therapy, and occupational therapy. This initiative reflects the Foundation's long-standing commitment to enhancing the community through philanthropy and addressing diverse educational needs since its inception in 1963.
Education - Higher Education Vocational & Trade Education Education - High School +5 more

Walking Classroom Grant Program

Alliance For A Healthier Generation
Private
United States
Unspecified amount in in-kind support
The Walking Classroom Grant Program, offered by the Alliance for a Healthier Generation, enables classroom teachers in public schools to receive donated materials for their students. This innovative program promotes physical activity while maintaining instructional time through engaging podcasts. Ideal for grades 3-8, it enhances cognitive function and retention. Schools with the greatest need, both socioeconomically and academically, are prioritized, ensuring that all students can benefit from this unique educational approach.
Academic Success & Enrichment Education - Middle School Education - Elementary School +2 more

DOE Computational Science Graduate Fellowship: Science & Engineering Track

United States Department of Energy (DOE)
Federal Government
United States
Unspecified amount
The DOE Computational Science Graduate Fellowship (CSGF) supports U.S. citizens and permanent residents pursuing Ph.D. degrees in computational sciences. Established in 1991, it provides a $45,000 annual stipend, full tuition, and a $1,000 professional development allowance over a maximum of four years. The program encourages interdisciplinary research, offering fellows practical experience in DOE laboratories, enhancing their careers in high-performance computing and scientific research across various fields.
Physics Biology Bioengineering +11 more

See, Test & Treat Grant - Multiyear Funding

College Of American Pathologists Foundation
Private
United States
Up to US $50,000
The See, Test & Treat Grant offers vital funding for cancer screening and health education programs targeting medically underserved communities. This pathologist-led initiative aims to reduce healthcare barriers, empower preventive care, and connect patients with local resources. Eligible organizations can apply for up to $50,000 over three years, fostering sustainable health improvements. The program emphasizes same-day results for screenings and culturally appropriate education, ensuring equitable access to essential healthcare services.
Reproductive Health Breast Cancer Reproductive Education +1 more

Operating Grants for Nonprofits in Iowa Highlights

Looking for operating grants for nonprofits in Iowa?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Iowa recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Iowa

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Operating grants for nonprofits in Iowa grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Operating grants for nonprofits in Iowa over $25K in average grant size

37 Operating grants for nonprofits in Iowa over $50K in average grant size

33 Operating grants for nonprofits in Iowa supporting general operating expenses

100+ Operating grants for nonprofits in Iowa supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Health & Medicine

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Iowa?

Most grants are due in the first quarter.

Q1
30.7%
Q2
24.4%
Q3
22.2%
Q4
22.7%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Iowa?

Grants are most commonly $18,750.

$500 $500 Min.
$18,750 $18.8 K Median
$195,866 $195.9 K Average
$3,000,000 $3 M Max.

Average Grant Size

What's the typical amount funded for Iowa?

Grants are most commonly $82,635.

$82,635

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Iowa year over year?

In 2024, funders in Iowa awarded a total of 28,032 grants.

2022 25,336

2023 26,582

2024 28,032

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Iowa given out in Iowa, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Iowa changing over time?

Funding has increased by 9.41%.

2022 $2,079,026,768

2023 $2,108,613,200
1.42%

2024 $2,307,128,111
9.41%

Iowa Counties That Receive the Most Funding

How does grant funding vary by county?

Polk County, Story County, and Johnson County receive the most funding.

County Total Grant Funding in 2024
Polk County $545,560,005
Story County $266,280,101
Johnson County $184,865,698
Linn County $166,016,288
Boone County $155,314,892