Best Small Grants for Nonprofits in Iowa

The CF Foundation/NIH K-Unfunded Award aims to support exceptional research projects in cystic fibrosis (CF) that have been approved by the NIH but lack funding. This award provides temporary financial assistance of up to $80,000 per year for two years to ensure that promising CF research continues without interruption. The initiative focuses on fostering a new generation of researchers dedicated to advancing CF studies while encouraging the NIH to provide long-term support.

The NIH StrokeNet initiative invites applications for multi-site exploratory and confirmatory clinical trials targeting interventions for stroke prevention, treatment, and recovery. This includes biomarker validation studies and ancillary studies to enhance active research. Successful applicants will collaborate within the NIH StrokeNet framework, with support from the National Coordinating Center and Data Management Center to ensure efficient study implementation and robust statistical analysis. Key deadlines for application submissions span from March 2024 to November 2026.

The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.

The Alzheimer’s Association Clinician Scientist Fellowship for All (AACSFA) aims to support the training of clinician scientists in Alzheimer’s and other dementias. This program encourages applications from individuals in underrepresented groups, emphasizing the value of diverse representation in clinical and scientific fields. The fellowship is designed for professionals with patient contact or diagnostic roles, fostering advancements in dementia research and care.

The Richard A. Shaw Fund Grant honors Richard A. Shaw's legacy by supporting nonprofit organizations focused on history, natural sciences, and outdoor education, as well as animal welfare initiatives, particularly equine therapy. Grants of up to $3,500 are available for public schools and qualifying nonprofits in the Omaha area. This fund aims to nurture an appreciation for history and nature in young minds, ensuring Richard's influence continues in the community.

The NINDS Faculty Development Award aims to enhance diversity in neuroscience research by supporting junior faculty from underrepresented backgrounds. This award provides essential research cost support, protected research time, and mentorship for individuals holding doctoral degrees within their first three years on a faculty tenure track. It specifically encourages research proposals that do not involve independent clinical trials, while allowing participation in trials led by mentors. Key application deadlines span from October 2024 to June 2027.

The AMA Foundation Physicians of Tomorrow Scholarship: Alliance Grassroots provides $10,000 in tuition assistance to medical students entering their final year. With a commitment to supporting diversity in medicine, this scholarship focuses on candidates interested in women's and children's health issues. Open to all medical students, it recognizes volunteerism and research in health-related fields. Since 1950, the AMA Foundation has awarded over $61 million in scholarships, fostering a diverse cohort of future healthcare professionals.

The Friends of Reservoirs: Small Grant program offers annual grants of $2,000 to member organizations of Friends of Reservoirs, with additional product donations bringing the total value over $3,500. This initiative, supported by generous sponsors, aims to enhance reservoir fisheries habitats. Applicants should note a $25 application fee, which contributes directly to the grant fund. This program focuses on fostering community engagement and improving aquatic ecosystems.

The African American Unity Fund Grant, managed by the Omaha Community Foundation, supports initiatives that benefit the African American community in Omaha. Funding prioritizes arts, basic human needs, community development, health, and capacity building. Collaboration among organizations is encouraged, and applicants must align with non-discrimination policies. There are no budget limits, and both new and previous applicants may apply. This initiative seeks impactful solutions tailored to the community's needs.

The LUNGevity Career Development Award supports emerging research leaders focused on lung cancer. It funds innovative projects aimed at enhancing early detection and personalized treatments, including targeted therapies and immunotherapy. With a maximum award of $300,000 over three years, this opportunity is limited to US applicants. The funding is contingent upon annual progress reviews, with the first payment expected after November 1, 2025. This award aims to foster groundbreaking advancements in lung cancer research.

The NIH Research Software Engineer (RSE) Award aims to provide salary support for outstanding Research Software Engineers who play a vital role in creating and sharing biomedical, behavioral, or health-related software and tools. This opportunity encourages RSEs to enhance the development of algorithms and support training for prospective users. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline.

The Spotlight Fund Grants aim to enhance racial equity in K-12 education by providing flexible funding to BIPOC educators. With grants ranging from $500 to $1,000 per educator, these funds are essential for sourcing tools and materials that support diverse student needs. As schools face budget cuts exacerbated by COVID-19, this initiative focuses on proven strategies that foster an inclusive learning environment for students of color, ensuring they have equal opportunities to thrive.

The Jonathan Larson Grants provide essential support to emerging musical theatre artists, helping composers, lyricists, and librettists further their creative endeavors. Established in memory of Jonathan Larson, creator of the iconic musical "Rent," these grants empower artists to create impactful work that resonates with contemporary culture. The program, sustained by the American Theatre Wing and the Larson Family, encourages professional growth and artistic exploration without the limitations of specific projects.

The Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional) aims to enhance cancer treatment by integrating imaging and liquid biopsy assays. This initiative, led by the National Cancer Institute (NCI), encourages grant applications focused on assessing therapy responses and resistance emergence in patients. Key deadlines for submissions span from February 2025 to January 2028, providing ample opportunities for researchers to contribute to this vital area of cancer research.

This funding opportunity invites applications for R01 grants focused on molecular imaging methods to explore cancer inflammation in vivo. It aims to enhance understanding of dynamic interactions between inflammation and cancer through innovative imaging techniques. The initiative encourages collaborations between cancer researchers and imaging scientists to leverage molecular imaging for identifying cellular physiology changes in response to treatment. Deadline dates for applications range from February 2025 to October 2027, emphasizing timely submission for prospective researchers.

The TTP Bridge Program aims to enhance the safety and accessibility of bridges in Tribal communities, addressing the urgent need for infrastructure improvements. With aging bridges affecting economic development and children's transportation, this program allows federally recognized Indian Tribes to apply for funding for planning, construction, and rehabilitation of bridges. By focusing on TTP bridges in poor condition, the initiative seeks to strengthen economic foundations and ensure better connectivity with markets, benefiting both families and communities.

The Minnesota Ovarian Cancer Alliance (MOCA) is offering grants for research focused on the early detection of ovarian cancer. With funding amounts of either $50,000 or $100,000 available, these grants support projects aimed at enhancing prevention strategies. Eligible applicants include U.S.-based researchers outside of Minnesota, and the awards will be distributed in November 2025. This initiative aims to foster innovative approaches to combat ovarian cancer effectively.

The American Heart Association (AHA) is launching the RFP for a Strategically Focused Research Network (SFRN) aimed at enhancing the early detection and delaying the progression of valvular heart disease. This initiative seeks collaborative proposals from researchers to address critical questions and advance understanding in this field. With a maximum budget of $4.4 million and a duration of four years, the AHA plans to award at least three grants based on scientific merit and alignment with its mission.

The Postdoctoral Fellowship Award, offered by the Foundation Fighting Blindness, supports postdoctoral researchers focusing on inherited retinal degenerations and dry age-related macular degeneration. This award provides $80,000 annually for two years, promoting innovative research and professional growth through mentorship. Applicants are expected to take the lead in their application process while receiving substantial guidance from their mentors, fostering collaboration and advancement in the field.

The National MS Society offers annual Research Grants for investigator-initiated proposals addressing key research questions from the Pathways to MS Cures Roadmap. These grants support diverse studies, including clinical and nonclinical research aimed at stopping MS disease activity, restoring function, and preventing new cases. Eligible applicants must hold an M.D. or Ph.D. and demonstrate relevance to the Society's research priorities. This funding opportunity promotes collaboration and focuses on underserved MS populations.

The Hank Riley Zolla Scholarship Fund, administered by the San Antonio Area Foundation, supports students pursuing nursing careers, including neonatal and child care. Eligible applicants must maintain a minimum 2.5 GPA and demonstrate financial need. This renewable scholarship can cover various degree levels, including associate, bachelor's, and vocational certificates. The fund aims to empower future healthcare professionals in the USA, ensuring quality education and community support for generations to come.

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

The Pilot Research Grant, offered by the Society of Interventional Radiology Foundation, supports innovative research in interventional radiology to improve patient care. Grants of up to $35,000 are available for full-time faculty and post-doctorates with relevant degrees in the U.S. and Canada. Applicants must be current SIR members and can submit proposals for preliminary data generation, enhancing their chances for future funding opportunities.

The Radiology Resident Research Grant, funded by The Society of Interventional Radiology Foundation, aims to promote research among residents in accredited clinical radiology training programs in the U.S. and Canada. With a budget of up to $20,000 for 12 months, this grant encourages innovative research projects that advance interventional radiology and improve patient care. Eligible applicants must designate a project advisor and secure a three-month commitment from their residency program, fostering a supportive research environment.

Kickstart Your Project with a Mini-Grant

At H2O for Life, we never want finances to be a barrier to participating in a service project. The H2O for Life Mini-Grants are meant to be a supportive resource for teachers and students who want to kick-start their projects with us. Mini-grants of up to $500 will be awarded to support teachers and students with the necessary funds for their service-learning programs.

Our Mission

H2O for Life offers a service-learning opportunity designed to engage, educate and inspire youth to take action to solve the global water crisis by raising awareness and funds to support implementation of water, sanitation and hygiene education projects for global partner schools.

Since 2007, nearly 1 million students from H2O for Life schools have supported water, sanitation, and hygiene education projects for partner schools in the developing world.

What is H2O for Life doing to address the global water crisis?

H2O for Life’s service-learning opportunities are designed to engage, educate, and inspire youth to become global citizens. Our innovative school-to-school approach helps young people develop a concern for others by taking a major global crisis and scaling it down to a manageable size — one water project in the developing world.

Through the service-learning opportunity we provide, students learn that they can make a tangible difference for the students in their partner school.

The Bar Success Intervention Grant Program, funded by AccessLex Institute, aims to enhance bar exam passage rates for at-risk law students and graduates. With grants ranging from $150,000 to $300,000 for programs lasting 12 to 24 months, the initiative seeks data-driven solutions that are scalable and replicable. Eligible applicants include U.S. nonprofit organizations and law schools. Programs should feature clear goals, measurable objectives, and a robust evaluation plan to ensure effectiveness and sustainability.

The Mary Kay Owens Memorial Fund, managed by the San Antonio Area Foundation, supports high school seniors from Bexar County pursuing education in physical therapy. This fund aims to assist students actively participating in varsity athletics who require financial aid to attend college. Established to make a meaningful impact, the foundation has been providing grants and scholarships since 1964, enhancing the quality of life in the San Antonio community.