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Best Lee County Grants for Nonprofits in Mississippi

Looking for grants for 501(c)(3) nonprofit organizations working in Lee County, Mississippi? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.56B

Total funding

$5K

Median grant

9,000+ grants
$2.56B total
$5K median

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9,137 Results based on applied filters

U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs:

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF State and Regional AI Infrastructure Hubs program seeks to enhance access to computational resources essential for AI-driven scientific exploration. By forming flexible consortia among government, academia, and industry, these hubs aim to foster innovation and workforce development in AI. The initiative aligns with national R&D priorities, emphasizing the critical role of AI in advancing scientific discovery and expanding infrastructure to support this mission across various disciplines.
Artificial Intelligence (AI)

National Foundation for the Centers for Disease Control and Prevention (363484)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $1,250,000
The National Foundation for the Centers for Disease Control and Prevention offers funding to support administrative expenses that bolster CDC's mission. This initiative enhances partnerships to address health threats both domestically and globally. Projects funded through this grant align with CDC's strategic goals, focusing on measurable outcomes such as program support and participation from various CDC Centers and Offices. Importantly, this grant only supports non-research activities.
Epidemiology & Public Health

Domestic Violence Prevention: Forensic Healthcare Services

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Domestic Violence Prevention grant aims to enhance access to forensic healthcare services for American Indian and Alaska Native victims of domestic violence and related issues. By fostering multidisciplinary partnerships, this initiative promotes trauma-informed care and improves victim support across IHS Areas. The focus is on developing comprehensive, culturally sensitive services that ensure timely interventions and coordinated responses to vulnerable populations, thereby enhancing overall victim well-being and safety.
Domestic Violence Crime Victim Services Violence Prevention +1 more

Tribal Epidemiology Centers

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Tribal Epidemiology Centers initiative aims to support currently unserved areas through a new cohort of TEC sites. Funded by the US Dept. of Health & Human Services: Indian Health Service, this program seeks to enhance public health capacity within tribal communities, ensuring access to essential health services and resources. The initiative underscores a commitment to addressing health disparities and promoting wellness among Native populations.
Epidemiology & Public Health Indigenous Health Systems Native American Services +1 more

Public Health Nursing

Indian Health Service
Federal Government
United States
Unspecified amount
The Public Health Nursing initiative aims to enhance the health and wellness of American Indian and Alaska Native men by implementing a culturally sensitive case management model. Through this program, Public Health Nurses will provide preventive health services, facilitate access to care, and encourage healthy lifestyle choices. By promoting early identification and management of health issues, the initiative strives to improve overall community health outcomes through targeted, collaborative interventions.
Epidemiology & Public Health Nursing Native American Services +1 more

National Urban Indian Health Program (Education and Research)

US Dept. of Health & Human Services: Indian Health Service
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The National Urban Indian Health Program aims to enhance behavioral health services for Urban Indian communities by fostering awareness, advocacy, and collaboration across the nation. By providing technical assistance and training to Urban Indian Organizations, the program seeks to improve access to culturally relevant behavioral health care for American Indian and Alaska Native populations residing in urban areas, ultimately leading to better health outcomes and community support.
Health & Medicine Mental Health & Psychiatric Diseases

Partnership with Common Fund Data Ecosystem Resources

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $1,200,000
The NIH Common Fund Data Ecosystem aims to enhance the reusability of biomedical data through collaboration between Common Fund programs and external data resources. This funding opportunity encourages projects that connect various biomedical data ecosystems, including the HEAL Data Ecosystem and the BRAIN Initiative. By fostering partnerships, the initiative seeks to improve the accessibility and interoperability of valuable datasets, ultimately advancing research efforts. Note that clinical trials are excluded from this funding opportunity.
Health & Medicine Biomedical informatics

Domestic Violence Prevention

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Domestic Violence Prevention (DVP) grant from the IHS aims to enhance the capacity of Tribes and Urban Indian Organizations to combat domestic and sexual violence. This initiative promotes culturally appropriate, trauma-informed services, focusing on victim advocacy and collaboration across sectors. It addresses critical issues like human trafficking and child maltreatment, ensuring long-term sustainability through evidence-based practices and data sharing, ultimately improving community health and safety for AI/AN populations.
Domestic Violence Violence Prevention

Urban Indian Health 4-in-1 Program

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Urban Indian Health 4-in-1 Program is designed to enhance the health and well-being of urban Native Americans through targeted initiatives in immunization, health promotion, disease prevention, mental health support, and addressing alcohol and substance abuse issues. Funded by the US Dept. of Health & Human Services, this program aims to improve access to essential health services and foster healthier communities among urban Indian populations.
Indigenous Health Systems Native American Services Indigenous Services +1 more

Youth Regional Treatment Center Aftercare Program

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Youth Regional Treatment Center Aftercare Program aims to support American Indian and Alaska Native youth in maintaining safety, sobriety, and success post-discharge from Youth Regional Treatment Centers. This initiative enhances culturally relevant, community-based aftercare by fostering care coordination, building partnerships, and addressing barriers to improve youth outcomes.
Youth Services Indigenous Health Systems Native American Services +1 more

Urban Indian Health Program - Education & Research

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Urban Indian Health Program - Education & Research collaborates with the US Dept. of Health & Human Services to enhance educational and research opportunities for urban Indian populations. This initiative aims to address health disparities and ensure that urban Indians have access to quality health services and information. By partnering with various urban Indian organizations, the program fosters community engagement and empowers individuals through education and research, ultimately improving health outcomes.
Education Native American Services Indigenous Services +1 more

Suicide Prevention, Intervention, and Postvention

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Suicide Prevention, Intervention, and Postvention program aims to reduce suicide rates among American Indian and Alaska Native populations. By enhancing care coordination and culturally relevant behavioral health services, it targets at-risk youth with early intervention strategies. This initiative emphasizes community engagement and collaboration among families, youth, and partners, fostering a comprehensive approach to prevention and support for those affected by suicide.
Crisis Intervention Suicide Prevention Native American Services +1 more

Tribal Self-Governance - Negotiation

Indian Health Service
Federal Government
United States
Unspecified amount
The Tribal Self-Governance Planning and Negotiation Cooperative Agreements are designed to assist tribes in planning and preparing to manage healthcare services for their members through the Tribal Self Governance Program. The Indian Health Service will provide three awards under this initiative, aiming to empower tribal organizations in their efforts to enhance healthcare delivery and self-determination.
Native American Services Indigenous Sovereignty & Rights Indigenous Services

Tribal Management Development

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Tribal Management Grant program is designed to empower tribes and tribal organizations by enabling them to take over functions and services of the Indian Health Service. Under the Public Law 93-638, this initiative aims to enhance their health management capabilities, fostering self-determination and improved healthcare delivery. The Indian Health Service plans to provide between five and sixteen awards to support this vital development in tribal health management.
Health & Medicine Indigenous Health Systems Native American Services +1 more

Tribal Self-Governance - Planning

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
Unspecified amount
The Tribal Self Governance - Planning program provides essential support for tribes to prepare for managing healthcare services for their communities. Through the Cooperative Agreements, the Indian Health Service aims to empower tribal organizations to take charge of their health needs, facilitating a smoother transition to self-governance in healthcare. This initiative reflects a commitment to enhancing tribal autonomy and improving health outcomes, with three awards available to eligible applicants.
Native American Services Indigenous Sovereignty & Rights Indigenous Services

Healthy Tomorrows Partnership for Children Program (HTPCP) (363533)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $75,000
The Healthy Tomorrows Partnership for Children Program (HTPCP) aims to enhance access to essential preventive clinical and public health services for children through community-driven initiatives. Funded by the US HHS: Health Resources & Services Administration (HRSA), this program focuses on empowering local communities to implement effective strategies that improve children's health outcomes and promote overall well-being. Projects funded under this initiative will play a vital role in ensuring healthier futures for children.
Epidemiology & Public Health Child Welfare Services

Alliance for Innovation on Maternal Health (AIM) Technical Assistance Center (363532)

Health Resources and Services Administration
Federal Government
American Samoa, Guam +4 more
Up to US $3,000,000
The Alliance for Innovation on Maternal Health (AIM) program aims to enhance maternal health outcomes by providing technical assistance across all U.S. states and territories. This initiative focuses on implementing best practices to improve safety during childbirth, ultimately saving lives. By supporting jurisdictions and birthing facilities involved in AIM, the program seeks to promote quality improvements in maternal health care, ensuring safer births and better health for mothers and infants.
Maternal And Perinatal Health

Foundation of the Federal Bar Association: Pathways to the Profession Grant

Foundation Of The Federal Bar Association
Private
United States
Up to US $10,000

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

  • Promote and support legal research and education;
  • Advance the science of jurisprudence;
  • Facilitate the administration of justice;
  • Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Pathways to the Profession Grant

The Pathways to the Profession Grant Program is designed to support educational, community service, or outreach projects and initiatives that support pathway programs and events that encourage high school, college and law school students, and newer lawyers, particularly those from underrepresented backgrounds, to pursue and succeed in a legal career through educational, networking, mentorship programs and other opportunities. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity) and other organizations to develop and support projects that make a lasting impact on their communities.

Applicants may only receive one (1) Foundation grant per year.

Workforce Preparation & Job Readiness Community Services Civic Leadership Development +2 more

Rett Syndrome (RS) Fund

Patient Advocate Foundation
Private
United States
US $2,200 - US $4,400

About

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Rett Syndrome (RS) Fund

Help with healthcare costs for Rett syndrome.

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. Check your eligibility with our quick and easy tools below. If this fund is open, apply today for an instant approval decision and use your grant funding right away

About the disease

Rett syndrome (RS or RTT) is a rare, genetic neurological disorder that causes a loss of motor and spoken language skills, as well as other physical and neurologic impairments early in life.

Diagnosis codes

F84.2

Neurological Diseases & Disorders

Pulmonary Hypertension Fund

Patient Advocate Foundation
Private
United States
US $4,000 - US $9,500
The Pulmonary Hypertension Fund, supported by the Patient Advocate Foundation, offers financial assistance for patients dealing with pulmonary hypertension. This fund covers essential healthcare costs, including medication copays and health insurance premiums. Patients must meet specific eligibility criteria, such as having a confirmed diagnosis and appropriate health insurance. Since 1996, the foundation has empowered millions to navigate healthcare challenges, ensuring they receive the care they need without financial burden.
Cardiovascular Diseases & Systems Chronic Obstructive Pulmonary Disease

Foundation of the Federal Bar Association: Community Outreach Grant

Foundation Of The Federal Bar Association
Private
United States
Up to US $10,000

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

  • Promote and support legal research and education;
  • Advance the science of jurisprudence;
  • Facilitate the administration of justice;
  • Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Community Outreach Grant

The Community Outreach Grants Program is designed to support projects and initiatives that provide legal services in local communities. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity) and other organizations to develop and support projects that make a lasting impact on their communities.

Applicants may only receive one (1) Foundation grant per year.

Legal Services Law

Primary Biliary Cholangitis (PBC) Fund

Patient Advocate Foundation
Private
United States
US $1,875 - US $2,500
The Primary Biliary Cholangitis (PBC) Fund, established by the Patient Advocate Foundation, offers vital financial assistance to patients managing the costs of treatment for primary biliary cholangitis. This fund covers out-of-pocket healthcare expenses such as medication copays and health insurance premiums, enabling individuals to access necessary treatments. Since its inception, the foundation has empowered millions by providing personalized support and resources, aiming to improve patient care and health outcomes.
Immune System Diseases

Pompe Disease Health Equity Fund

Patient Advocate Foundation
Private
United States
US $4,000 - US $9,500
The Pompe Disease Health Equity Fund, supported by the Patient Advocate Foundation, offers crucial financial assistance to patients diagnosed with Pompe disease. This fund helps cover out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligibility requires a confirmed diagnosis and treatment plan, along with meeting specific income criteria. With a mission to enhance health equity, the fund empowers patients to access necessary care and improve their quality of life.
Musculoskeletal Diseases

Foundation of the Federal Bar Association: Civics Education Grant

Foundation Of The Federal Bar Association
Private
United States
Up to US $10,000

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

  • Promote and support legal research and education;
  • Advance the science of jurisprudence;
  • Facilitate the administration of justice;
  • Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Civics Education Grant

The Civics Grant Program is designed to support projects and initiatives that promote a wider public understanding of democratic principles, the judicial system and the rule of law. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity), and other organizations to develop and support projects in their communities that foster public understanding of the rights and responsibilities of American citizenship, particularly among younger Americans.

Applicants may only receive one (1) Foundation grant per year.

Law Social Justice / Human Rights Civic Engagement & Education +3 more

Pompe Disease Fund

Patient Advocate Foundation
Private
United States
US $4,000 - US $9,500
The Pompe Disease Fund, supported by the Patient Advocate Foundation, offers vital financial assistance to individuals diagnosed with Pompe disease. This fund covers out-of-pocket healthcare costs including medication copays and health insurance premiums. Eligible patients must have a confirmed diagnosis and be receiving treatment or planning to start within 60 days. With over 3.8 million patients helped since its inception, the fund aims to alleviate financial burdens and enhance access to necessary treatments.
Musculoskeletal Diseases

Elaine R. “Boots” Fisher Award

Foundation Of The Federal Bar Association
Private
United States
US $1,000

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

  • Promote and support legal research and education;
  • Advance the science of jurisprudence;
  • Facilitate the administration of justice;
  • Foster improvements in the practice of Federal law

Elaine R. “Boots” Fisher Award

Elaine R. “Boots” Fisher was the wife of former National and Northern District of Ohio Chapter President Stanley M. Fisher. Sadly, in 1989 “Boots” Fisher succumbed to illness. The Elaine R. “Boots” Fisher Award is presented as a memorial to the outstanding and unselfish contributions made by “Boots” Fisher to improve the quality of life and opportunities of all persons. She gave of herself willingly to help others to overcome adversity.

The award is intended to stimulate, encourage and recognize exemplary community, public and charitable service by members of the Federal Bar Association. Nominations should demonstrate:

  • Continuous general or specific contributions to community, charitable or public service;
  • Specific accomplishments for which the nominee is primarily responsible which serve to enhance, promote and encourage community, charitable and/or public service; and
  • Specific personal achievements of the nominee which serve to provide inspiration and hope to others. The charitable contribution made in the name of the recipient reflects the essence of the person in whose honor this award is established.

The charitable contribution made in the name of the recipient reflects the essence of the person in whose honor this award is established. A cash contribution in the amount of $1,000 will be made in the recipient’s name to a charity selected by the recipient. The charity selected must meet the requirements of Section 501(c)(3) of the Internal Revenue Code and contributions to charitable organizations which promote the provision of legal services and the administration of justice are encouraged but not required.

Legal Services Law Community Services

Acute Myeloid Leukemia (AML) Fund Program

Patient Advocate Foundation
Private
American Samoa, Guam +4 more
Up to US $8,600

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Acute Myeloid Leukemia (AML) Fund

Help with healthcare costs for acute myeloid leukemia

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Health Care Access & Delivery Health Disparities & Social Determinants of Health

Lee County Grants for Nonprofits Highlights

Looking for Lee County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Lee County grants recommended for your specific programs in Mississippi.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Mississippi

Average Grant Size

What's the typical amount funded for Mississippi?

Grants are most commonly $94,687.

$94,687

Total Number of Grants

What's the total number of grants in Lee County Grants for Nonprofits year over year?

In 2024, funders in Mississippi awarded a total of 8,599 grants.

2022 7,983

2023 8,165

2024 8,599

Top Grant Focus Areas

Among all the Lee County Grants for Nonprofits given out in Mississippi, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Lee County Grants for Nonprofits changing over time?

Funding has increased by 2.35%.

2022 $634,985,073

2023 $789,259,908
24.30%

2024 $807,768,252
2.35%

Mississippi Counties That Receive the Most Funding

How does grant funding vary by county?

Oktibbeha County, Hinds County, and Lafayette County receive the most funding.

County Total Grant Funding in 2024
Oktibbeha County $274,520,115
Hinds County $230,593,243
Lafayette County $93,085,023
Harrison County $41,719,363
Madison County $39,767,542